iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mtr-058422

Ensembl Protein ID

AES68881

UniProt Accession

A8W462; A8W462_MEDTR

Genbank Protein ID

ABW70161.1; AES68881.1

Protein Name

E3 ubiquitin-protein ligase

Genbank Nucleotide ID

EU189947; CM001219

Gene Name

MTR_3g017590

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MTR_3g017590	AES68881	AES68881

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	34.38	4.00e-40	161.00	IUUC-Dme-031700

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Medicago truncatula

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

MTSSNPFFDD IRSRPGVDPP QTEESTEIPE LVNDPIQTVV KPNGTVSSSV RELLECPVCL 60
NAMYPPIHQC SNGHTLCSGC KPRVHDRCPT CRHELGNIRC LALEKVAASL ELPCKYQGFG 120

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Nucleotide Sequence
(Fasta)

CTTTTCTCAT TTGTATTTTC TCGAGAAAAT CTCTCTCTTA CTTACTCTCT CCTCTTAGTT 60
TGAATTCTTG TTCCACTTTG CAGACGCGCA CAAATGAAGG GTCTTCTCTA CTTTCTTATT 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina

Gene Ontology

GO:0005634--C:nucleus
GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

mtr:MTR_3g017590

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-003118	Amborella trichopoda	81.31	7.00e-152	528.00
IUUC-Dme-031700	Drosophila melanogaster	34.94	2.00e-37	148.00
IUUC-Gma-042926	Glycine max	89.80	1.00e-169	587.00
IUUC-Opr-070341	Ochotona princeps	26.58	3.00e-12	64.70
IUUC-Oan-073701	Ornithorhynchus anatinus	24.83	3.00e-12	64.70
IUUC-Oba-075789	Oryza barthii	83.44	9.00e-156	541.00
IUUC-Obr-076037	Oryza brachyantha	83.44	2.00e-154	538.00
IUUC-Ogl-077148	Oryza glaberrima	83.44	9.00e-156	541.00
IUUC-Ogu-078042	Oryza glumaepatula	83.44	8.00e-156	542.00
IUUC-Oin-079325	Oryza indica	83.44	2.00e-155	540.00
IUUC-Olo-080244	Oryza longistaminata	83.44	5.00e-156	543.00
IUUC-Oni-082163	Oryza nivara	83.44	9.00e-156	541.00
IUUC-Oru-084833	Oryza rufipogon	83.44	2.00e-155	540.00
IUUC-Osa-085316	Oryza sativa	83.44	2.00e-155	540.00
IUUC-Oga-088114	Otolemur garnettii	36.90	1.00e-42	166.00
IUUC-Pva-103132	Pteropus vampyrus	25.16	7.00e-11	60.50
IUUC-Sit-110245	Setaria italica	82.45	1.00e-151	528.00
IUUC-Stu-112474	Solanum tuberosum	85.57	1.00e-159	555.00
IUUC-Sbi-114035	Sorghum bicolor	82.78	8.00e-153	531.00
IUUC-Tru-118250	Takifugu rubripes	34.64	2.00e-41	161.00
IUUC-Tsy-119548	Tarsius syrichta	31.48	4.00e-09	53.90
IUUC-Tca-121228	Theobroma cacao	87.21	8.00e-163	565.00
IUUC-Tur-126049	Triticum urartu	80.92	2.00e-149	520.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence