iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Opu-083863

Ensembl Protein ID

OPUNC07G25650.1

UniProt Accession

A0A0E0LQ45; A0A0E0LQ45_ORYPU

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
OPUNC07G25650	OPUNC07G25650.1	OPUNC07G25650.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	2.00e-168	561.8	443	930

Active Site

Position(s)	Description	Evidence
624	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvn 89
           YD Qi ++G++ q+kl++++ ++vG g+lGcE+lKnL+l+Gv     g++t++D+d +e+snl+rqFLfr++++g+ K+ vaa+a+  +n +  
   Q: 443  YDAQISVFGSKLQKKLEETNTFVVGSGALGCEFLKNLALMGVscsakGKLTITDDDVIEKSNLSRQFLFRDWNIGQAKSTVAAAAASAINHNLC 536
           ********************************************************************************************** PP
   S: 90   veaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketp 180
           ++a +++ ++++e+++   F + +dvV++aldn+ ar++++ +cl+ ++ l+esgtlG + +++ +i++lte y +s+dpp+k++P+ct+ ++p
   Q: 537  IDALQNRACPDTENVFhdtFWEGLDVVINALDNVNARMYMDMRCLYFQKALLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAPMCTVHSFP 630
           **************8899999999********************************************************************** PP
   S: 181  naaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikqllksfec 262
            +++h+++wa              +n +l++ a+      k   ++ ++ + +v++ l +e+   fe++i++a+ +f+ +++n +kql+  f+ 
   Q: 631  HNIDHCLTWArsefegllektpGEVNSFLSNPAQYAASMRKAGDAQARDLLVRVSECLGKERCGLFEDCIRWARLKFEDYFSNRVKQLTFTFPE 724
           ****************9999998889999999999999999999999*********************************************** PP
   S: 263  divtkskspfwv.........................................................sfcsna.ealqvpekvekdeevvka 298
           d  t+ ++pfw+                                                         +f++ +  ++ ++ek+++   ++ +
   Q: 725  DAATSTGAPFWSapkrfprplqfsvadpshihfimsasilraesfgiaipdwtkniskladavskvavpEFEPKKgVSIVTDEKATSLSSASVD 818
           *****************************************************98776666666655553322221233334444444444333 PP
   S: 299  sap.lylllralerfekk..kgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKv 387
           +a+ +  ll++le+ +k+  +g +++ ++fekddd   ++dl+  +an+ra +++i++ +d+ + k iag+iipaiat +a+  Gl+++E++Kv
   Q: 819  DASvIDDLLAKLEECAKRlpPGFQMKPIQFEKDDDTnfHMDLISGFANMRARNYSIPE-VDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKV 911
           3338888999999999875589************************************.*********************************** PP
   S: 388  vsg..kfeplknfflfdae 404
           + g  + e ++n+f ++a+
   Q: 912  IAGghPIEDYRNTFANLAL 930
           ***99999******99875 PP

Organism

Oryza punctata

Protein Sequence
(Fasta)

MLPTTNKRAA GPEEDDDRAA DPKKAKIAQN GSTNGVAVPE IDEDLHSRQL AVYGRETMRR 60
LFASHVLVSG LNGLGAEIAK NLALAGVKSV TLHDVNNVEM WDLSANFFLS ENDIGKNRAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTCCGTGAC CTCGCGAAAG GGCGGTAGCA AGAGGAGGGT ATAAATAGCC GAGGGCAAAG 60
CCCTCTCTCG ATCATCAGCA CCGCCGCCGC CTCCTCTGCA CTGCAGCTTC TTCTCTTCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000144	Aegilops tauschii	88.29	0.00e+00	1818.00
IUUC-Ago-007873	Ashbya gossypii	46.19	0.00e+00	837.00
IUUC-Bdi-014009	Brachypodium distachyon	84.70	0.00e+00	1754.00
IUUC-Cho-024682	Choloepus hoffmanni	37.29	1.00e-102	367.00
IUUC-Hvu-047191	Hordeum vulgare	88.29	0.00e+00	1821.00
IUUC-Lpe-051299	Leersia perrieri	93.51	0.00e+00	1982.00
IUUC-Mvi-060437	Microbotryum violaceum	43.34	0.00e+00	811.00
IUUC-Oan-073268	Ornithorhynchus anatinus	41.82	0.00e+00	635.00
IUUC-Oba-075934	Oryza barthii	95.23	0.00e+00	2011.00
IUUC-Obr-076244	Oryza brachyantha	92.79	0.00e+00	1907.00
IUUC-Ogl-077762	Oryza glaberrima	95.23	0.00e+00	2009.00
IUUC-Ogu-078305	Oryza glumaepatula	95.13	0.00e+00	2011.00
IUUC-Oin-080154	Oryza indica	95.32	0.00e+00	2009.00
IUUC-Olo-081089	Oryza longistaminata	95.71	0.00e+00	2019.00
IUUC-Oni-082447	Oryza nivara	95.23	0.00e+00	2010.00
IUUC-Oru-084469	Oryza rufipogon	95.42	0.00e+00	2014.00
IUUC-Osa-085625	Oryza sativa	95.23	0.00e+00	2008.00
IUUC-Pma-094214	Petromyzon marinus	44.19	6.00e-34	135.00
IUUC-Sit-110294	Setaria italica	87.12	0.00e+00	1901.00
IUUC-Sbi-114774	Sorghum bicolor	87.12	0.00e+00	1892.00
IUUC-Tae-125676	Triticum aestivum	85.58	0.00e+00	1861.00
IUUC-Tur-126011	Triticum urartu	85.48	0.00e+00	1790.00
IUUC-Vpa-130716	Vicugna pacos	39.30	0.00e+00	671.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence