iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Zm00001d005127	Zm00001d005127_T014	Zm00001d005127_T014
Zm00001d005127	Zm00001d005127_T003	Zm00001d005127_T003
Zm00001d005127	Zm00001d005127_T021	Zm00001d005127_T021
Zm00001d005127	Zm00001d005127_T008	Zm00001d005127_T008
Zm00001d005127	Zm00001d005127_T012	Zm00001d005127_T012
Zm00001d005127	Zm00001d005127_T004	Zm00001d005127_T004
Zm00001d005127	Zm00001d005127_T016	Zm00001d005127_T016
Zm00001d005127	Zm00001d005127_T002	Zm00001d005127_T002

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.20e-116	391.8	3375	3714
UBD/Alpha-Helix/UBA	6.90e-08	34.4	1281	1320

Active Site

Position(s)	Description	Evidence
3682	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlld 89
            +dlk rl v+f+gEeg+d+gG+tre+++lls+ ++++ + lf ++ ++++t+qpnp+s ++ +ehl++F+f+Gr+++kal+dg+lld
   Q: 3375 TQDLKGRLTVQFQGEEGIDAGGLTREWYQLLSRVIFDKGTLLF-TTVGNNATFQPNPNSDFQ-TEHLSYFKFVGRVVAKALFDGQLLD 3460
           589************************************9999.566688999*******96.5************************ PP
   S: 90   lplsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfs..vseei.....lgetkeeeLkpgGenipVtneNk 170
           +++++sfyk++lg k++++d+e++dp++y++lk+++en   d+++l   ltfs  ++ee+       e++++eLkpgG+ni+Vt+e k
   Q: 3461 VHFTRSFYKHILGAKVTYHDIEAIDPDYYRNLKWMLEN---DVSDL-PYLTFSmdPDEEKhilyeKTEVTDYELKPGGRNIRVTEETK 3544
           ************************************99...67776.44444422666658895445566778*************** PP
   S: 171  eeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefss 258
           +eYv+lv+e++l++ i+ q++ f eGf+e++p +l+slF+ +elelli+G +eid++dlk++t+y  gy++ sp+iqwFwev+++fs+
   Q: 3545 QEYVDLVAEHILTTAIRPQINGFLEGFTELVPRDLISLFNDKELELLISGLPEIDLDDLKANTEY-IGYSAASPVIQWFWEVVRAFSK 3631
           *****************************************************************.55******************** PP
   S: 259  eerkafLqFvTgssrlPlgGfaelk....prlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFel 335
           e+ +++LqFvTg+s++Pl+Gf++l+    p++f+i k ++s+ rlPs++TCfn+L+LPeY+ske+l+e+Ll+Ai+e+ +gF++
   Q: 3632 EDMARLLQFVTGTSKVPLEGFKALQgisgPQRFQIYKaYGSPGRLPSAHTCFNQLDLPEYTSKEQLEERLLLAIHEAsEGFGF 3714
           *************************************999*************************************9***85 PP

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
           de++++ +veMGF+r +a + Lr+   n++e+A+++L+++
   Q: 1281 DESAIATIVEMGFSRARAEESLRSVrTNSVEMATDWLFNH 1320
           79**********************99************97 PP

Organism

Zea mays

Protein Sequence
(Fasta)

MKLKRRRAVE VPPSIKSFIN SVTTVPLEDV ELPLKDFAWE FDKGDFHHWL DLFNHFDSFF 60
ESYIKSRKDL HLEDNFLDVD PPFPREALLQ ILRVSKLILE NCTNRHFSSF FEQHLSALLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCGTGTAG CAACTAGCAA CACCTCTTCT CCTTTTACTT CGCCTCGCCT CGCCATAACG 60
ACACGCGCAT CTCCCTACCT CGATACGATT CTTCGTCTTC TCTTCCCCGC GATCGCGCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR025527--DUF4414
IPR010309--E3_Ub_ligase_DUF908
IPR010314--E3_Ub_ligase_DUF913
IPR000569--HECT_dom
IPR015940--UBA
IPR009060--UBA-like

PROSITE

PS50237--HECT
PS50030--UBA

Pfam

PF14377--DUF4414
PF06012--DUF908
PF06025--DUF913
PF00632--HECT
PF00627--UBA

SMART

SM00119--HECTc
SM00165--UBA

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-003044	Amborella trichopoda	53.25	0.00e+00	1926.00
IUUC-Aly-006083	Arabidopsis lyrata	50.12	0.00e+00	2002.00
IUUC-Ath-007160	Arabidopsis thaliana	50.04	0.00e+00	2041.00
IUUC-Bra-016637	Brassica rapa	51.12	0.00e+00	1708.00
IUUC-Ggr-039946	Gaeumannomyces graminis	39.76	1.00e-134	476.00
IUUC-Gga-040309	Gallus gallus	57.05	4.00e-97	347.00
IUUC-Gma-044247	Glycine max	55.53	0.00e+00	3374.00
IUUC-Kpa-049228	Komagataella pastoris	38.83	5.00e-126	446.00
IUUC-Lpe-050915	Leersia perrieri	74.66	0.00e+00	5022.00
IUUC-Mtr-058088	Medicago truncatula	53.24	0.00e+00	1989.00
IUUC-Mac-065557	Musa acuminata	54.72	0.00e+00	1528.00
IUUC-Opr-070443	Ochotona princeps	45.04	5.00e-95	342.00
IUUC-Oba-075252	Oryza barthii	74.79	0.00e+00	5022.00
IUUC-Obr-076762	Oryza brachyantha	75.22	0.00e+00	5027.00
IUUC-Ogl-077590	Oryza glaberrima	76.31	0.00e+00	1709.00
IUUC-Ogu-077981	Oryza glumaepatula	73.74	0.00e+00	4949.00
IUUC-Oin-079663	Oryza indica	72.86	0.00e+00	4712.00
IUUC-Olo-080326	Oryza longistaminata	74.93	0.00e+00	5024.00
IUUC-Ome-081289	Oryza meridionalis	82.35	0.00e+00	1360.00
IUUC-Oni-082342	Oryza nivara	74.85	0.00e+00	5058.00
IUUC-Opu-083428	Oryza punctata	75.40	0.00e+00	5019.00
IUUC-Oru-084559	Oryza rufipogon	74.77	0.00e+00	5019.00
IUUC-Osa-086200	Oryza sativa	75.35	0.00e+00	1869.00
IUUC-Ptr-091629	Pan troglodytes	45.29	5.00e-95	342.00
IUUC-Pma-094364	Petromyzon marinus	43.38	2.00e-89	322.00
IUUC-Ppa-095834	Physcomitrella patens	45.36	0.00e+00	1526.00
IUUC-Pop-099520	Populus trichocarpa	55.69	0.00e+00	3462.00
IUUC-Ppe-102109	Prunus persica	56.73	0.00e+00	3536.00
IUUC-Ssl-108514	Sclerotinia sclerotiorum	43.46	6.00e-95	341.00
IUUC-Smo-109428	Selaginella moellendorffii	44.05	0.00e+00	2432.00
IUUC-Sit-110149	Setaria italica	85.74	0.00e+00	5679.00
IUUC-Sly-111285	Solanum lycopersicum	52.78	0.00e+00	2186.00
IUUC-Stu-112501	Solanum tuberosum	66.31	6.00e-120	423.00
IUUC-Sbi-113794	Sorghum bicolor	88.72	0.00e+00	5195.00
IUUC-Tsy-118806	Tarsius syrichta	44.53	1.00e-92	334.00
IUUC-Tca-121646	Theobroma cacao	56.01	0.00e+00	3475.00
IUUC-Tbe-127408	Tupaia belangeri	42.82	3.00e-85	310.00
IUUC-Vda-129886	Verticillium dahliae	39.34	1.00e-132	469.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence