iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033393

UUCD1 version

UUC-EqC-00853

Ensembl Protein ID

ENSECAP00000000598.1

UniProt Accession

F7DN02; F7DN02_HORSE

Protein Name

Uncharacterized protein

Gene Name

BIRC2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000000609.1	ENSECAT00000000750.1	ENSECAP00000000598.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	93.16	0.00e+00	1089.00	IUUC-Hsa-045769

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Equus caballus

Protein Sequence
(Fasta)

MEDSTILSSW TVGNKQKMKY DFSCELYRMS TYSTFPTGVP VSERSLARAG FYYTGVNDKV 60
KCFCCGLMLD NWKQGDNPIE KHKQLYPSCS FIQNLVSVTS LESTSKNTSS PMRNSFTHSL 120

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Nucleotide Sequence
(Fasta)

ATGGAAGATA GCACAATCTT GTCAAGTTGG ACAGTCGGCA ACAAACAAAA AATGAAATAT 60
GACTTTTCAT GTGAACTCTA CAGAATGTCT ACATATTCAA CTTTCCCCAC CGGTGTTCCT 120

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Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR028795--C-IAP1
IPR001315--CARD
IPR011029--DEATH-like_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01282--BIR_REPEAT_1
PS50143--BIR_REPEAT_2
PS50209--CARD
PS50089--ZF_RING_2

Pfam

PF00653--BIR
PF00619--CARD

SMART

SM00238--BIR
SM00114--CARD
SM00184--RING

Gene Ontology

GO:0035631--C:CD40 receptor complex
GO:0005737--C:cytoplasm
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005634--C:nucleus
GO:0043027--F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0003713--F:transcription coactivator activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0071356--P:cellular response to tumor necrosis factor
GO:1990001--P:inhibition of cysteine-type endopeptidase activity involved in apoptotic process
GO:0070266--P:necroptotic process
GO:0060546--P:negative regulation of necroptotic process
GO:1902443--P:negative regulation of ripoptosome assembly involved in necroptotic process
GO:0001890--P:placenta development
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:1902524--P:positive regulation of protein K48-linked ubiquitination
GO:1902523--P:positive regulation of protein K63-linked ubiquitination
GO:1902527--P:positive regulation of protein monoubiquitination
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0051726--P:regulation of cell cycle
GO:0045595--P:regulation of cell differentiation
GO:0050727--P:regulation of inflammatory response
GO:1901222--P:regulation of NIK/NF-kappaB signaling
GO:2000377--P:regulation of reactive oxygen species metabolic process
GO:0034121--P:regulation of toll-like receptor signaling pathway

KEGG

ecb:100061273

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002369	Ailuropoda melanoleuca	91.68	0.00e+00	1100.00
IUUC-Apl-003549	Anas platyrhynchos	71.88	0.00e+00	863.00
IUUC-Aca-004515	Anolis carolinensis	69.44	0.00e+00	801.00
IUUC-Aly-006460	Arabidopsis lyrata	37.04	2.00e-09	56.20
IUUC-Acl-008330	Aspergillus clavatus	30.68	2.00e-13	71.20
IUUC-Afl-008648	Aspergillus flavus	32.76	1.00e-14	75.10
IUUC-Ani-009424	Aspergillus nidulans	30.46	4.00e-13	70.10
IUUC-Ang-009667	Aspergillus niger	30.67	6.00e-12	66.20
IUUC-Ame-011877	Astyanax mexicanus	56.72	0.00e+00	667.00
IUUC-Bta-012450	Bos taurus	91.86	0.00e+00	1016.00
IUUC-Bol-015478	Brassica oleracea	31.90	8.00e-10	61.60
IUUC-Bra-017001	Brassica rapa	32.76	4.00e-10	62.80
IUUC-Cja-018895	Callithrix jacchus	92.17	0.00e+00	1058.00
IUUC-Cfa-020419	Canis familiaris	91.99	0.00e+00	1097.00
IUUC-Cpo-022048	Cavia porcellus	89.82	0.00e+00	1047.00
IUUC-Cho-024277	Choloepus hoffmanni	89.65	0.00e+00	1023.00
IUUC-Cin-025521	Ciona intestinalis	31.32	4.00e-76	279.00
IUUC-Csv-026182	Ciona savignyi	30.13	4.00e-68	252.00
IUUC-Cne-027029	Cryptococcus neoformans	30.23	8.00e-12	65.50
IUUC-Dre-028647	Danio rerio	57.21	0.00e+00	655.00
IUUC-Dor-030796	Dipodomys ordii	74.13	4.00e-100	358.00
IUUC-Eeu-035114	Erinaceus europaeus	87.81	0.00e+00	1001.00
IUUC-Fca-036034	Felis catus	90.98	0.00e+00	1061.00
IUUC-Fal-037656	Ficedula albicollis	70.72	0.00e+00	853.00
IUUC-Gmo-038477	Gadus morhua	56.11	0.00e+00	630.00
IUUC-Gga-040601	Gallus gallus	72.37	0.00e+00	874.00
IUUC-Gac-041467	Gasterosteus aculeatus	57.89	0.00e+00	639.00
IUUC-Gma-043487	Glycine max	43.48	1.00e-07	54.70
IUUC-Ggo-044857	Gorilla gorilla	92.82	0.00e+00	1070.00
IUUC-Hsa-045769	Homo sapiens	93.16	0.00e+00	1074.00
IUUC-Itr-048441	Ictidomys tridecemlineatus	92.01	0.00e+00	1086.00
IUUC-Lch-050259	Latimeria chalumnae	62.33	0.00e+00	729.00
IUUC-Loc-052169	Lepisosteus oculatus	55.61	9.00e-171	593.00
IUUC-Laf-053449	Loxodonta africana	90.68	0.00e+00	1041.00
IUUC-Meu-056241	Macropus eugenii	69.68	0.00e+00	726.00
IUUC-Mtr-058211	Medicago truncatula	34.91	5.00e-09	59.30
IUUC-Mga-059947	Meleagris gallopavo	72.04	0.00e+00	871.00
IUUC-Mvi-060388	Microbotryum violaceum	24.50	1.00e-06	48.10
IUUC-Mdo-062352	Monodelphis domestica	80.50	0.00e+00	927.00
IUUC-Mmu-064340	Mus musculus	85.02	0.00e+00	989.00
IUUC-Mac-065489	Musa acuminata	38.78	1.00e-08	53.50
IUUC-Mpu-065890	Mustela putorius furo	90.54	0.00e+00	1018.00
IUUC-Mlu-068077	Myotis lucifugus	93.18	0.00e+00	1117.00
IUUC-Nfi-068591	Neosartorya fischeri	32.30	6.00e-13	69.70
IUUC-Nle-070081	Nomascus leucogenys	91.99	0.00e+00	1072.00
IUUC-Opr-070561	Ochotona princeps	85.98	0.00e+00	983.00
IUUC-Ont-071776	Oreochromis niloticus	55.97	0.00e+00	650.00
IUUC-Oan-073604	Ornithorhynchus anatinus	77.48	0.00e+00	899.00
IUUC-Ocu-073963	Oryctolagus cuniculus	91.49	0.00e+00	1060.00
IUUC-Ogu-078452	Oryza glumaepatula	47.73	2.00e-07	50.10
IUUC-Ome-081435	Oryza meridionalis	45.65	2.00e-06	46.60
IUUC-Oni-082044	Oryza nivara	43.64	1.00e-09	58.20
IUUC-Opu-084085	Oryza punctata	41.67	9.00e-07	47.80
IUUC-Oru-085060	Oryza rufipogon	46.51	6.00e-07	48.90
IUUC-Ola-086446	Oryzias latipes	54.25	3.00e-177	615.00
IUUC-Oga-087976	Otolemur garnettii	92.32	0.00e+00	1078.00
IUUC-Oar-090097	Ovis aries	93.37	0.00e+00	1120.00
IUUC-Ptr-091137	Pan troglodytes	92.99	0.00e+00	1073.00
IUUC-Pan-092673	Papio anubis	94.49	0.00e+00	1089.00
IUUC-Psi-092992	Pelodiscus sinensis	73.27	0.00e+00	858.00
IUUC-Pfo-096790	Poecilia formosa	56.54	4.00e-180	624.00
IUUC-Pab-098734	Pongo abelii	93.49	0.00e+00	1076.00
IUUC-Pop-098944	Populus trichocarpa	42.59	4.00e-10	58.90
IUUC-Pca-100708	Procavia capensis	73.58	2.00e-178	618.00
IUUC-Ppe-101533	Prunus persica	45.65	6.00e-08	55.50
IUUC-Pva-102788	Pteropus vampyrus	94.66	0.00e+00	1093.00
IUUC-Rno-105026	Rattus norvegicus	81.30	0.00e+00	960.00
IUUC-Sja-107720	Schizosaccharomyces japonicus	32.89	6.00e-15	76.60
IUUC-Ssc-115804	Sus scrofa	91.51	0.00e+00	1067.00
IUUC-Tgu-116931	Taeniopygia guttata	71.22	0.00e+00	866.00
IUUC-Tru-117620	Takifugu rubripes	55.43	0.00e+00	629.00
IUUC-Tsy-118958	Tarsius syrichta	65.44	0.00e+00	683.00
IUUC-Tni-119683	Tetraodon nigroviridis	55.57	0.00e+00	629.00
IUUC-Tbe-127523	Tupaia belangeri	92.32	0.00e+00	1092.00
IUUC-Ttr-128954	Tursiops truncatus	91.99	0.00e+00	1066.00
IUUC-Vpa-130441	Vicugna pacos	92.99	0.00e+00	1086.00
IUUC-Xma-132984	Xiphophorus maculatus	56.09	0.00e+00	633.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence