iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

EL5.1; EL5; Os02g0559800; LOC_Os02g35329; P0435E12.16; EL5.2; EL5; Os02g0560200; LOC_Os02g35347; P0435E12.20; EL5.3; EL5; Os02g0560600; LOC_Os02g35365; P0435E12.24; EL5.4; EL5; Os02g0561000; LOC_Os02g35383; P0435E12.28; EL5.5; EL5; Os02g0561400; LOC_Os02g35401; P0435E12.32; EL5.6; EL5; Os02g0561800; LOC_Os02g35429; P0435E12.37

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
OS02G0559800	OS02T0559800-01	OS02T0559800-01

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/RING	RING	17559513; 17056617

Classification

Family	E-value	Score	Start	End
E3 activity/RING/RING	3.10e-08	34.9	134	176

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdg..plvlp.CgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+Cl +++dg   ++lp CgH fha+C+ +w         + +CPlCr
   Q: 134  CAVCLAELEDGeeARFLPrCGHGFHAECVDMW------LGSHSTCPLCR 176
           ********66555777777*************......**********8 PP

Organism

Oryza sativa

Functional Description
(View)

Functions as a E3 ubiquitin-protein ligase in cooperation with the E2 ubiquitin conjugating enzymes UBC5A and UBC5B. Involved in root development. Required for the maintenance of cell viability after the initiation of root primordial formation. May mediate the degradation of cytotoxic proteins produced in root cells after the actions of auxin, cytokinin and jasmonic acid. Mediates 'Lys-48'-linked polyubiquitination of MBP in vitro.

Protein Sequence
(Fasta)

MVRGVEQGGP AMDESSSSSS PSPVSAPAGQ AAMTAGGIAT VAAVLIVFAA LTLAFVLLQC 60
YCDERRRAVT TTSTSGRGRR PRPRRRSGSG GDGGTGGGVD PEVLRSLPVT VYSRSTAAAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTCACATAT GCATGTGACG GTCGATTATT ATGGTGCGGG GTGTCGAGCA GGGCGGCCCC 60
GCCATGGACG AGTCTTCGTC GTCGTCGTCG CCGTCGCCGG TGTCCGCGCC TGCAGGGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0002--3D-structure
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005886--C:plasma membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0051301--P:cell division
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0016567--P:protein ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0048364--P:root development

KEGG

osa:107276747; osa:107276748; osa:107276749; osa:107276750; osa:107276751; osa:4329685

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000503	Aegilops tauschii	49.31	1.00e-35	142.00
IUUC-Bdi-014557	Brachypodium distachyon	42.86	4.00e-36	144.00
IUUC-Hvu-047609	Hordeum vulgare	48.03	1.00e-41	162.00
IUUC-Lpe-051726	Leersia perrieri	55.91	1.00e-51	195.00
IUUC-Obr-076042	Oryza brachyantha	71.43	2.00e-42	164.00
IUUC-Ogl-077858	Oryza glaberrima	96.95	2.00e-78	284.00
IUUC-Ogu-078181	Oryza glumaepatula	90.62	7.00e-72	263.00
IUUC-Oin-079371	Oryza indica	65.38	2.00e-19	88.20
IUUC-Ome-081378	Oryza meridionalis	90.17	5.00e-61	226.00
IUUC-Oni-083072	Oryza nivara	93.69	7.00e-69	252.00
IUUC-Opu-083718	Oryza punctata	72.45	5.00e-44	169.00
IUUC-Oru-084619	Oryza rufipogon	100.00	2.00e-73	268.00
IUUC-Sit-109797	Setaria italica	58.82	3.00e-27	114.00
IUUC-Sbi-114599	Sorghum bicolor	52.75	4.00e-41	160.00
IUUC-Tae-124919	Triticum aestivum	53.88	3.00e-44	170.00
IUUC-Tur-126867	Triticum urartu	57.80	1.00e-40	157.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence