iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-007080

UUCD1 version

UUC-ArT-00119

Ensembl Protein ID

AT5G14420.3

UniProt Accession

Q9LY87; RGLG2_ARATH

Genbank Protein ID

AAZ14078.1; CAB87781.1; AED92028.1; AED92029.1; AED92030.1; AED92031.1; AAM20448.1; AAN15568.1

Protein Name

E3 ubiquitin-protein ligase RGLG2; RING domain ligase 2

Genbank Nucleotide ID

DQ086862; AL163817; CP002688; CP002688; CP002688; CP002688; AY099597; BT000249

Gene Name

RGLG2; At5g14420; F18O22.210

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT5G14420	AT5G14420.3	AT5G14420.3

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
Protein-protein Interaction
PINA	HINT	Mentha
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/RING	RING	15644464; 20113438; 17586653

Classification

Family	E-value	Score	Start	End
E3 activity/RING/RING	3.4	9.2	425	458

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCl+ +kd     +CgH+ + +C              ++CP+Cr
   Q: 425  CPICLSNPKD-MA-FGCGHQTCCEC----------GPDLQMCPICR 458
           ********99.44.69*********..........9999******8 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates the formation of 'Lys-63'-linked ubiquitin chains. Regulates apical dominance by acting on the auxin transport proteins abundance (PubMed:17586653). Mediates ubiquitination and subsequent proteasomal degradation of ERF053 in response to drought stress. Acts as a negative regulator of drought stress response (PubMed:22095047).

Protein Sequence
(Fasta)

MGTGNSKENW RQSSFRSTSA SSASPSSSSW ASQQSYPQYG AESYNYPPPP SYAQPPEYTQ 60
PPPPLYSTQP YSAPSYSAPP SQSYGSDNKK RLERKYSKIS DDYSSLEQVT EALARAGLES 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTACCAACC TTCGATTTTA AAGAGCGGTG AGATAATTCA ACATCTGTCA AAGATAAAGC 60
TTTCACCTTT TCTTAACGAA TTAGGTATAG GTAAATTGCA TCTTCTAATA ATGTCAGAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0938--Abscisic acid signaling pathway
KW-1003--Cell membrane
KW-0181--Complete proteome
KW-0449--Lipoprotein
KW-0472--Membrane
KW-0479--Metal-binding
KW-0519--Myristate
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0346--Stress response
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR010734--Copine
IPR002035--VWF_A
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF07002--Copine

SMART

SM00327--VWA

Gene Ontology

GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0009738--P:abscisic acid-activated signaling pathway
GO:0009850--P:auxin metabolic process
GO:0009690--P:cytokinin metabolic process
GO:0080148--P:negative regulation of response to water deprivation

KEGG

ath:AT5G14420

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001090	Aegilops tauschii	73.33	3.00e-150	523.00
IUUC-Atr-003148	Amborella trichopoda	70.54	4.00e-144	503.00
IUUC-Apl-003690	Anas platyrhynchos	31.91	2.00e-26	113.00
IUUC-Aca-005177	Anolis carolinensis	32.74	2.00e-27	116.00
IUUC-Aly-006212	Arabidopsis lyrata	95.32	0.00e+00	728.00
IUUC-Ame-011404	Astyanax mexicanus	29.97	5.00e-27	114.00
IUUC-Bta-013305	Bos taurus	31.42	6.00e-26	111.00
IUUC-Bdi-014521	Brachypodium distachyon	71.73	9.00e-158	549.00
IUUC-Bol-016568	Brassica oleracea	82.69	0.00e+00	734.00
IUUC-Bra-017730	Brassica rapa	91.10	0.00e+00	709.00
IUUC-Cel-018357	Caenorhabditis elegans	49.24	1.00e-66	250.00
IUUC-Cja-019806	Callithrix jacchus	29.87	2.00e-28	119.00
IUUC-Cpo-022547	Cavia porcellus	28.75	2.00e-27	117.00
IUUC-Cre-022882	Chlamydomonas reinhardtii	60.66	2.00e-92	331.00
IUUC-Csa-023455	Chlorocebus sabaeus	30.46	2.00e-28	119.00
IUUC-Cgl-026474	Colletotrichum gloeosporioides	30.36	7.60e-02	32.30
IUUC-Dre-027464	Danio rerio	32.03	2.00e-28	120.00
IUUC-Dor-030419	Dipodomys ordii	33.61	2.00e-26	112.00
IUUC-Ete-032325	Echinops telfairi	30.45	2.00e-23	103.00
IUUC-Eca-033239	Equus caballus	33.20	2.00e-26	113.00
IUUC-Eeu-034962	Erinaceus europaeus	34.96	3.00e-25	108.00
IUUC-Fal-036712	Ficedula albicollis	32.97	5.00e-26	111.00
IUUC-Gmo-038771	Gadus morhua	33.20	2.00e-27	116.00
IUUC-Gga-040253	Gallus gallus	30.29	9.00e-27	114.00
IUUC-Gac-042313	Gasterosteus aculeatus	31.85	1.00e-27	117.00
IUUC-Gma-042812	Glycine max	74.93	4.00e-168	583.00
IUUC-Ggo-045589	Gorilla gorilla	29.87	2.00e-28	119.00
IUUC-Hsa-046724	Homo sapiens	29.64	6.00e-28	118.00
IUUC-Hvu-047606	Hordeum vulgare	72.28	1.00e-161	561.00
IUUC-Itr-048186	Ictidomys tridecemlineatus	33.61	5.00e-26	112.00
IUUC-Lpe-051660	Leersia perrieri	71.00	1.00e-162	565.00
IUUC-Loc-052575	Lepisosteus oculatus	32.92	7.00e-28	117.00
IUUC-Mcc-055340	Macaca mulatta	30.46	1.00e-28	120.00
IUUC-Meu-056737	Macropus eugenii	34.02	1.00e-26	114.00
IUUC-Mtr-058065	Medicago truncatula	72.41	2.00e-167	581.00
IUUC-Mga-059862	Meleagris gallopavo	31.02	5.00e-27	115.00
IUUC-Mmr-061707	Microcebus murinus	30.42	1.00e-29	123.00
IUUC-Mdo-061966	Monodelphis domestica	31.17	3.00e-26	112.00
IUUC-Mmu-064072	Mus musculus	30.10	8.00e-27	114.00
IUUC-Mac-065151	Musa acuminata	69.82	8.00e-162	562.00
IUUC-Mlu-067845	Myotis lucifugus	32.92	8.00e-26	110.00
IUUC-Nle-069867	Nomascus leucogenys	30.10	4.00e-29	122.00
IUUC-Opr-070639	Ochotona princeps	33.20	4.00e-25	108.00
IUUC-Ont-071452	Oreochromis niloticus	32.92	3.00e-27	115.00
IUUC-Oan-073203	Ornithorhynchus anatinus	31.28	6.00e-26	111.00
IUUC-Oba-075802	Oryza barthii	71.79	1.00e-158	552.00
IUUC-Obr-076544	Oryza brachyantha	72.18	7.00e-158	549.00
IUUC-Ogl-077517	Oryza glaberrima	71.79	1.00e-158	552.00
IUUC-Ogu-078399	Oryza glumaepatula	71.79	9.00e-159	552.00
IUUC-Oin-079126	Oryza indica	71.79	1.00e-158	552.00
IUUC-Olo-080405	Oryza longistaminata	70.57	1.00e-142	498.00
IUUC-Ome-081659	Oryza meridionalis	67.74	6.00e-157	546.00
IUUC-Oni-082524	Oryza nivara	71.79	1.00e-158	552.00
IUUC-Opu-083235	Oryza punctata	70.88	1.00e-156	545.00
IUUC-Oru-084447	Oryza rufipogon	71.13	1.00e-156	545.00
IUUC-Osa-085497	Oryza sativa	71.79	1.00e-158	552.00
IUUC-Ola-087558	Oryzias latipes	33.33	3.00e-28	118.00
IUUC-Oar-089901	Ovis aries	33.61	5.00e-26	112.00
IUUC-Ptr-090898	Pan troglodytes	29.87	4.00e-29	121.00
IUUC-Pan-092519	Papio anubis	30.46	4.00e-28	120.00
IUUC-Psi-093065	Pelodiscus sinensis	31.02	4.00e-26	112.00
IUUC-Ppa-095320	Physcomitrella patens	56.55	7.00e-127	446.00
IUUC-Pab-098607	Pongo abelii	32.79	2.00e-25	110.00
IUUC-Pop-099752	Populus trichocarpa	73.56	3.00e-164	570.00
IUUC-Pca-100224	Procavia capensis	32.52	4.00e-24	105.00
IUUC-Ppe-101655	Prunus persica	73.06	1.00e-173	601.00
IUUC-Pva-102684	Pteropus vampyrus	33.61	8.00e-26	111.00
IUUC-Pgr-103353	Puccinia graminis	24.63	8.00e-03	33.50
IUUC-Rno-104855	Rattus norvegicus	30.77	5.00e-26	112.00
IUUC-Sha-106541	Sarcophilus harrisii	34.02	1.00e-26	113.00
IUUC-Smo-109395	Selaginella moellendorffii	58.65	7.00e-134	469.00
IUUC-Sit-110666	Setaria italica	70.68	4.00e-155	540.00
IUUC-Sly-111212	Solanum lycopersicum	74.61	6.00e-168	582.00
IUUC-Stu-111981	Solanum tuberosum	71.81	6.00e-169	586.00
IUUC-Sar-113010	Sorex araneus	34.96	3.00e-24	105.00
IUUC-Sbi-114268	Sorghum bicolor	71.92	2.00e-160	557.00
IUUC-Tgu-117459	Taeniopygia guttata	34.84	2.00e-27	116.00
IUUC-Tni-119926	Tetraodon nigroviridis	32.21	1.00e-29	124.00
IUUC-Tca-121637	Theobroma cacao	74.37	9.00e-170	589.00
IUUC-Tae-124799	Triticum aestivum	72.18	1.00e-158	552.00
IUUC-Tur-126194	Triticum urartu	70.14	1.00e-136	479.00
IUUC-Tbe-127814	Tupaia belangeri	31.05	1.00e-23	103.00
IUUC-Ttr-128480	Tursiops truncatus	33.61	2.00e-26	113.00
IUUC-Vpa-130269	Vicugna pacos	30.86	3.00e-25	109.00
IUUC-Vvi-131538	Vitis vinifera	78.03	0.00e+00	629.00
IUUC-Xtr-132921	Xenopus tropicalis	33.45	6.00e-28	118.00
IUUC-Xma-133656	Xiphophorus maculatus	34.01	1.00e-27	117.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence