iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Ath-007187

Ensembl Protein ID

AT5G37890.1

UniProt Accession

Q9FKD7; SINL7_ARATH

Genbank Protein ID

BAB09035.1; AED94244.1; AAL62428.1; AAM48041.1

Protein Name

E3 ubiquitin-protein ligase SINA-like 7; RING-type E3 ubiquitin transferase SINA-like 7; Seven in absentia-like protein 7

Genbank Nucleotide ID

AB012241; CP002688; AY072436; AY114722

Gene Name

At5g37890; K18L3.9

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT5G37890	AT5G37890.1	AT5G37890.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	PINA	HINT	Mentha
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/RING	RING	24015288

Organism

Arabidopsis thaliana

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It probably triggers the ubiquitin-mediated degradation of different substrates.

Protein Sequence
(Fasta)

MVGAAILESP GEGIGSNSIL SQKRQLSSSD AAKRDAKKRS TMLMDLEILD CPICYEAFTI 60
PIFQCDNGHL ACSSCCPKLN NKCPACTSPV GHNRCRAMES VLESILIPCP NAKLGCKKNV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TATAGTTTGT GCCATTGTCT CCTTTCTCTG TAAAACCATC CATCAATGAA CAAAATCAAC 60
TAAATTCTCT ATTTGCCTCT CTCAGTTTTC GAGAAGACTA AAAGCGAATT TAGGGTTTAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR001370--BIR_rpt
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina

Gene Ontology

GO:0005634--C:nucleus
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0009411--P:response to UV
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ath:AT5G37890

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-005653	Arabidopsis lyrata	76.30	4.00e-126	443.00
IUUC-Ang-009779	Aspergillus niger	30.71	7.00e-08	51.20
IUUC-Bci-013939	Botrytis cinerea	36.96	6.00e-03	34.70
IUUC-Bdi-014026	Brachypodium distachyon	31.64	8.00e-30	123.00
IUUC-Bol-016089	Brassica oleracea	63.82	2.00e-92	331.00
IUUC-Bra-016844	Brassica rapa	61.92	5.00e-93	333.00
IUUC-Hvu-047394	Hordeum vulgare	34.33	1.00e-29	122.00
IUUC-Mtr-058360	Medicago truncatula	34.82	2.00e-35	141.00
IUUC-Oan-072802	Ornithorhynchus anatinus	32.00	1.00e-04	40.80
IUUC-Opu-083398	Oryza punctata	34.01	1.00e-27	117.00
IUUC-Ptt-103895	Puccinia triticina	24.49	1.80e-01	29.30
IUUC-Ssl-108572	Sclerotinia sclerotiorum	36.96	4.00e-03	34.70
IUUC-Tae-124152	Triticum aestivum	30.71	2.00e-32	132.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence