iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Ath-007669

UUCD1 version

UUC-ArT-01641

Ensembl Protein ID

AT3G24515.3

UniProt Accession

Q941B6; Q9LV54; UBC37_ARATH

Genbank Protein ID

AAY44876.1; BAB02001.1; AEE76912.1; AAK96485.1; AAL31249.1

Protein Name

Probable ubiquitin-conjugating enzyme E2 37; E2 ubiquitin-conjugating enzyme 37; Ubiquitin carrier protein 37

Genbank Nucleotide ID

DQ027050; AB020746; CP002686; AY052292; AY061922

Gene Name

UBC37; At3g24515; MOB24.7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT3G24515	AT3G24515.3	AT3G24515.3
AT3G24515	AT3G24515.1	AT3G24515.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	5.10e-36	124.4	68	182

Active Site

Position(s)	Description	Evidence
99	Glycyl thioester intermediate	{ECO:0000255\|PROSITE-ProRule:PRU00388, ECO:0000255\|PROSITE-ProRule:PRU10133}

Domain Profile

E2/UBC

   S: 26   dltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk..eeekWspalsvesvllsiqsllaepnpesplnee 121
           d++++  +i+Gpedt+Y++g+F+l+i++pe+YPf+PP v+f t+i+hPn++++G++Cl+il+  ++ +W+p l++++vl+s+  ll+epnp+++l  e
   Q: 68   DIHDFFPEIEGPEDTVYANGIFNLKIQIPERYPFQPPIVSFATPIYHPNIDNSGRICLDILNlpPKGAWQPSLNISTVLTSMRLLLSEPNPDDGLMCE 165
           57778889*****************************************************98899******************************** PP
   S: 122  aaellkknreeykkkvr 138
           +++++k nr++++ k+r
   Q: 166  VSREYKYNRQTFDYKAR 182
           ************99887 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.

Protein Sequence
(Fasta)

MAQAARLSLR MQKELKLLLS DPPHGASFPH LSSAANGSGD FSTFSTIDAR QLFFISSFFN 60
FQIQICFDIH DFFPEIEGPE DTVYANGIFN LKIQIPERYP FQPPIVSFAT PIYHPNIDNS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCTTCCCCC GCCAGTGCCA ATCACTGCAA AATCCCTTTT GCCCCCAATT GTTTTTCAGA 60
AAGCTGTGAA GACGAAGAAG TTTCTGAATC AATGGCTCAA GCAGCGAGAT TAAGCCTGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0006974--P:cellular response to DNA damage stimulus
GO:0000209--P:protein polyubiquitination

KEGG

ath:AT3G24515

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000366	Aegilops tauschii	60.41	1.00e-62	233.00
IUUC-Aml-001392	Ailuropoda melanoleuca	62.10	9.00e-46	175.00
IUUC-Atr-003069	Amborella trichopoda	48.97	9.00e-60	223.00
IUUC-Apl-003914	Anas platyrhynchos	65.29	5.00e-47	179.00
IUUC-Aca-004381	Anolis carolinensis	44.72	2.00e-45	174.00
IUUC-Aly-006059	Arabidopsis lyrata	81.60	0.00e+00	651.00
IUUC-Ame-011372	Astyanax mexicanus	45.59	1.00e-44	171.00
IUUC-Bta-012479	Bos taurus	57.94	4.00e-44	169.00
IUUC-Bdi-014043	Brachypodium distachyon	64.97	9.00e-69	254.00
IUUC-Bol-016011	Brassica oleracea	68.28	8.00e-143	499.00
IUUC-Bra-017419	Brassica rapa	65.13	5.00e-133	466.00
IUUC-Cja-019773	Callithrix jacchus	60.48	1.00e-44	171.00
IUUC-Cfa-020043	Canis familiaris	59.84	3.00e-45	173.00
IUUC-Cpo-021481	Cavia porcellus	58.87	1.00e-43	168.00
IUUC-Csa-024083	Chlorocebus sabaeus	55.33	2.00e-44	171.00
IUUC-Cho-024386	Choloepus hoffmanni	60.48	4.00e-44	170.00
IUUC-Cin-025419	Ciona intestinalis	56.52	9.00e-40	155.00
IUUC-Csv-026224	Ciona savignyi	44.51	9.00e-42	162.00
IUUC-Cme-027179	Cyanidioschyzon merolae	53.04	2.00e-33	134.00
IUUC-Dre-028800	Danio rerio	45.45	6.00e-44	169.00
IUUC-Dno-029833	Dasypus novemcinctus	60.48	3.00e-44	170.00
IUUC-Ete-032625	Echinops telfairi	60.33	7.00e-39	152.00
IUUC-Eca-033821	Equus caballus	60.66	8.00e-44	168.00
IUUC-Eeu-034578	Erinaceus europaeus	67.02	1.00e-37	147.00
IUUC-Fca-036398	Felis catus	46.99	2.00e-45	174.00
IUUC-Fal-037564	Ficedula albicollis	50.56	1.00e-47	181.00
IUUC-Gmo-039142	Gadus morhua	63.48	6.00e-43	165.00
IUUC-Gga-041054	Gallus gallus	66.96	4.00e-46	176.00
IUUC-Gac-041370	Gasterosteus aculeatus	62.61	2.00e-41	160.00
IUUC-Ggo-045370	Gorilla gorilla	59.68	8.00e-44	169.00
IUUC-Hsa-046513	Homo sapiens	60.48	2.00e-44	170.00
IUUC-Hvu-047694	Hordeum vulgare	62.44	8.00e-66	244.00
IUUC-Itr-049076	Ictidomys tridecemlineatus	54.86	4.00e-45	173.00
IUUC-Lch-050484	Latimeria chalumnae	55.48	1.00e-43	168.00
IUUC-Lpe-051409	Leersia perrieri	57.46	8.00e-38	150.00
IUUC-Loc-051967	Lepisosteus oculatus	46.70	3.00e-44	170.00
IUUC-Laf-053377	Loxodonta africana	62.10	3.00e-45	173.00
IUUC-Mcc-055453	Macaca mulatta	55.33	2.00e-44	171.00
IUUC-Meu-056745	Macropus eugenii	62.70	9.00e-46	175.00
IUUC-Mga-059729	Meleagris gallopavo	65.22	6.00e-46	176.00
IUUC-Mmr-060581	Microcebus murinus	62.10	6.00e-45	172.00
IUUC-Mdo-062434	Monodelphis domestica	48.33	7.00e-45	174.00
IUUC-Mmu-064379	Mus musculus	61.29	2.00e-44	171.00
IUUC-Mac-064647	Musa acuminata	58.65	2.00e-58	217.00
IUUC-Mpu-066713	Mustela putorius furo	64.96	2.00e-45	174.00
IUUC-Mlu-067525	Myotis lucifugus	44.20	4.00e-42	162.00
IUUC-Nle-069757	Nomascus leucogenys	60.48	3.00e-44	170.00
IUUC-Opr-070756	Ochotona princeps	61.74	3.00e-43	167.00
IUUC-Ont-071956	Oreochromis niloticus	45.99	2.00e-44	170.00
IUUC-Oan-072745	Ornithorhynchus anatinus	62.31	3.00e-44	170.00
IUUC-Ocu-074423	Oryctolagus cuniculus	61.48	6.00e-44	169.00
IUUC-Oba-075569	Oryza barthii	63.45	7.00e-68	250.00
IUUC-Obr-076131	Oryza brachyantha	62.44	2.00e-66	246.00
IUUC-Ogl-077132	Oryza glaberrima	63.45	7.00e-68	250.00
IUUC-Ogu-078880	Oryza glumaepatula	63.45	5.00e-68	251.00
IUUC-Oin-079748	Oryza indica	63.45	5.00e-68	251.00
IUUC-Olo-080501	Oryza longistaminata	64.47	4.00e-70	258.00
IUUC-Ome-081248	Oryza meridionalis	63.45	9.00e-68	250.00
IUUC-Oni-083033	Oryza nivara	63.45	5.00e-68	251.00
IUUC-Opu-083664	Oryza punctata	63.45	8.00e-68	250.00
IUUC-Oru-084580	Oryza rufipogon	63.45	5.00e-68	251.00
IUUC-Osa-085721	Oryza sativa	63.45	5.00e-68	251.00
IUUC-Ola-087559	Oryzias latipes	60.16	2.00e-44	171.00
IUUC-Oga-088420	Otolemur garnettii	61.29	8.00e-45	172.00
IUUC-Oar-090082	Ovis aries	55.91	2.00e-41	160.00
IUUC-Ptr-091134	Pan troglodytes	60.48	3.00e-44	170.00
IUUC-Pan-091735	Papio anubis	55.33	2.00e-44	171.00
IUUC-Psi-094064	Pelodiscus sinensis	61.98	2.00e-45	174.00
IUUC-Pma-094609	Petromyzon marinus	61.74	5.00e-42	162.00
IUUC-Ppa-095553	Physcomitrella patens	49.73	2.00e-50	192.00
IUUC-Pfo-096710	Poecilia formosa	61.16	8.00e-43	166.00
IUUC-Pab-098126	Pongo abelii	60.48	2.00e-44	170.00
IUUC-Pop-099108	Populus trichocarpa	68.50	9.00e-75	273.00
IUUC-Pca-100338	Procavia capensis	63.11	2.00e-45	174.00
IUUC-Ppe-101239	Prunus persica	54.11	3.00e-66	245.00
IUUC-Pva-102756	Pteropus vampyrus	67.00	1.00e-39	154.00
IUUC-Rno-105211	Rattus norvegicus	63.56	4.00e-44	170.00
IUUC-Sha-106969	Sarcophilus harrisii	55.56	6.00e-34	136.00
IUUC-Smo-109052	Selaginella moellendorffii	50.00	2.00e-41	160.00
IUUC-Sit-110464	Setaria italica	64.47	8.00e-65	240.00
IUUC-Sly-110971	Solanum lycopersicum	66.14	2.00e-65	242.00
IUUC-Stu-112126	Solanum tuberosum	66.14	2.00e-66	246.00
IUUC-Sar-113633	Sorex araneus	53.90	2.00e-45	174.00
IUUC-Sbi-114875	Sorghum bicolor	64.97	8.00e-69	254.00
IUUC-Ssc-116375	Sus scrofa	60.00	2.00e-42	164.00
IUUC-Tgu-117292	Taeniopygia guttata	50.26	5.00e-47	179.00
IUUC-Tru-118157	Takifugu rubripes	65.31	9.00e-37	145.00
IUUC-Tsy-119260	Tarsius syrichta	60.32	4.00e-45	173.00
IUUC-Tni-120162	Tetraodon nigroviridis	59.06	1.00e-42	164.00
IUUC-Tca-121255	Theobroma cacao	65.67	4.00e-61	228.00
IUUC-Tae-123184	Triticum aestivum	60.41	1.00e-62	233.00
IUUC-Tbe-127296	Tupaia belangeri	60.66	5.00e-44	169.00
IUUC-Ttr-128443	Tursiops truncatus	59.02	2.00e-43	167.00
IUUC-Vpa-130689	Vicugna pacos	52.74	1.00e-43	168.00
IUUC-Vvi-130925	Vitis vinifera	63.41	1.00e-69	254.00
IUUC-Xma-133779	Xiphophorus maculatus	61.98	3.00e-43	167.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence