iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ate-010347

Ensembl Protein ID

CADATEAP00005107

UniProt Accession

Q0CM90; Q0CM90_ASPTN

Genbank Protein ID

EAU34263.1

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

CH476600

Gene Name

ATEG_05194

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADATEAG00005107	CADATEAT00005107	CADATEAP00005107

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	5.00e-56	189.5	4	261

Active Site

Position(s)	Description	Evidence
111	Nucleophile	{ECO:0000256\|PIRSR:PIRSR038120-1}
194	Proton donor	{ECO:0000256\|PIRSR:PIRSR038120-1}

Domain Profile

DUB/UCH

   S: 5    vkewleLesdPglftllvedfgvkrdiqveelysLdpenlgly..................qepvegllllFkinekressrksqvtsndlev 79
           + +w ++esd g+ft l+e++gvk+  q+eel sLd ++++++                    pv+g+++lFk+  +   s     t+ +  +
   Q: 4    GGGWSTIESDEGVFTSLIENLGVKDI-QFEELISLDADTIRSLryfpppastvrdtpnlttASPVYGVIFLFKYLRDPAPSS----TTPQDGT 91
           579*********************98.***************9*******************************98877776....2333489 PP
   S: 80   vdediiktiffakqvigNsCatyAllsvllnc....edkl.ldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqd 167
            d ++   +ffa q+i+N+C+t+A+lsv+ln     ++   +d+G++l  +k++t ++ p+ +++al+n++ ++ +hn++ar  ++  ++ + 
   Q: 92   YDTNASTDLFFAAQTIQNACGTQAILSVILNQdtaaSHAPpIDIGSELRSFKDFTTGFPPDLRGEALSNSETIRTAHNAFARASPFVDETTRP 184
           *******************************97776556689*******************************************98887775 PP
   S: 168  edneqytkeafhfvsyvningrlyeldglkpfPldlgkkketeelkdklkvvraflerikllesdeirfnllaivadrrvik 249
           + +   + +++hf++y+++ng lyeldgl+p+P+ +g++  ++  ++ + v++    ri  + ++e rfnl+a+v d r   
   Q: 185  ARD--DDPDVYHFIAYTPVNGTLYELDGLQPYPISHGACDADTFPEKVIGVLQ---RRIARYPEGETRFNLMAVVRDLRARA 261
           554..4889*****************************888777777777776...9*******************987543 PP

Organism

Aspergillus terreus

Protein Sequence
(Fasta)

MADGGGWSTI ESDEGVFTSL IENLGVKDIQ FEELISLDAD TIRSLRYFPP PASTVRDTPN 60
LTTASPVYGV IFLFKYLRDP APSSTTPQDG TYDTNASTDL FFAAQTIQNA CGTQAILSVI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCGACG GAGGCGGCTG GAGCACGATC GAATCAGACG AAGTGAGCTC AAAGCCTCGA 60
CAACCACCTC TAAGCCTACC ACAAAGCTAA CCTAACTTAG GGCGTCTTCA CATCGCTCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR017390--Ubiquitinyl_hydrolase_UCH37

Pfam

PF01088--Peptidase_C12

Gene Ontology

GO:0034399--C:nuclear periphery
GO:0031595--C:nuclear proteasome complex
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000936	Aegilops tauschii	38.26	2.00e-58	217.00
IUUC-Aml-001866	Ailuropoda melanoleuca	36.64	2.00e-55	207.00
IUUC-Atr-002966	Amborella trichopoda	46.01	1.00e-54	205.00
IUUC-Apl-003306	Anas platyrhynchos	33.79	8.00e-48	182.00
IUUC-Aca-004763	Anolis carolinensis	36.80	2.00e-55	207.00
IUUC-Aly-005581	Arabidopsis lyrata	39.71	3.00e-55	206.00
IUUC-Ath-007283	Arabidopsis thaliana	39.42	5.00e-57	212.00
IUUC-Ago-007999	Ashbya gossypii	35.76	1.00e-44	171.00
IUUC-Acl-008231	Aspergillus clavatus	76.88	9.00e-137	477.00
IUUC-Afl-008557	Aspergillus flavus	78.79	3.00e-141	492.00
IUUC-Afu-008988	Aspergillus fumigatus	77.48	9.00e-137	477.00
IUUC-Ani-009420	Aspergillus nidulans	69.44	8.00e-122	427.00
IUUC-Ang-009859	Aspergillus niger	72.78	5.00e-122	428.00
IUUC-Aor-010145	Aspergillus oryzae	78.79	3.00e-141	492.00
IUUC-Ame-010791	Astyanax mexicanus	36.86	2.00e-56	210.00
IUUC-Bgr-012298	Blumeria graminis	55.69	3.00e-97	346.00
IUUC-Bta-013251	Bos taurus	37.05	7.00e-56	208.00
IUUC-Bci-013786	Botrytis cinerea	62.46	8.00e-115	404.00
IUUC-Bdi-014132	Brachypodium distachyon	43.37	5.00e-57	212.00
IUUC-Bol-015611	Brassica oleracea	38.62	1.00e-57	214.00
IUUC-Bra-017769	Brassica rapa	38.62	2.00e-57	214.00
IUUC-Cel-018604	Caenorhabditis elegans	34.12	4.00e-48	183.00
IUUC-Cja-019768	Callithrix jacchus	33.80	4.00e-50	189.00
IUUC-Cfa-020207	Canis familiaris	36.64	2.00e-55	207.00
IUUC-Cpo-021925	Cavia porcellus	34.83	8.00e-50	188.00
IUUC-Cre-022919	Chlamydomonas reinhardtii	44.80	1.00e-53	201.00
IUUC-Csa-023958	Chlorocebus sabaeus	37.35	4.00e-56	209.00
IUUC-Cho-024928	Choloepus hoffmanni	42.86	2.00e-13	68.20
IUUC-Cin-025771	Ciona intestinalis	36.50	4.00e-53	199.00
IUUC-Csv-026149	Ciona savignyi	37.06	5.00e-56	209.00
IUUC-Cgl-026424	Colletotrichum gloeosporioides	48.11	1.00e-80	290.00
IUUC-Cne-026955	Cryptococcus neoformans	35.38	1.00e-47	181.00
IUUC-Cme-027104	Cyanidioschyzon merolae	31.55	6.00e-40	155.00
IUUC-Dre-027409	Danio rerio	37.05	7.00e-56	208.00
IUUC-Dno-028921	Dasypus novemcinctus	36.34	1.00e-54	204.00
IUUC-Dor-030891	Dipodomys ordii	38.51	1.00e-24	106.00
IUUC-Dse-031170	Dothistroma septosporum	57.66	1.00e-102	363.00
IUUC-Dme-031677	Drosophila melanogaster	36.20	2.00e-51	194.00
IUUC-Ete-032646	Echinops telfairi	37.86	1.00e-30	126.00
IUUC-Eca-033776	Equus caballus	38.55	1.00e-48	184.00
IUUC-Eeu-035305	Erinaceus europaeus	45.95	6.00e-24	102.00
IUUC-Fca-035846	Felis catus	33.89	8.00e-51	192.00
IUUC-Fal-037597	Ficedula albicollis	38.55	6.00e-49	185.00
IUUC-Fox-037670	Fusarium oxysporum	56.43	2.00e-89	320.00
IUUC-Fso-038243	Fusarium solani	56.43	1.00e-88	318.00
IUUC-Gmo-038499	Gadus morhua	32.93	1.00e-46	177.00
IUUC-Ggr-039975	Gaeumannomyces graminis	53.67	8.00e-83	298.00
IUUC-Gga-040904	Gallus gallus	36.94	4.00e-56	209.00
IUUC-Gac-042058	Gasterosteus aculeatus	36.56	3.00e-54	203.00
IUUC-Gma-043030	Glycine max	46.93	6.00e-57	212.00
IUUC-Ggo-044699	Gorilla gorilla	41.96	1.00e-53	201.00
IUUC-Hsa-046227	Homo sapiens	36.94	6.00e-56	209.00
IUUC-Hvu-047359	Hordeum vulgare	37.82	3.00e-58	216.00
IUUC-Itr-048989	Ictidomys tridecemlineatus	33.79	1.00e-50	191.00
IUUC-Lch-049829	Latimeria chalumnae	37.16	2.00e-56	210.00
IUUC-Lpe-050899	Leersia perrieri	39.13	1.00e-58	218.00
IUUC-Loc-052264	Lepisosteus oculatus	36.75	4.00e-54	202.00
IUUC-Lma-053110	Leptosphaeria maculans	58.92	1.00e-91	327.00
IUUC-Laf-053639	Loxodonta africana	36.64	2.00e-55	207.00
IUUC-Mcc-055506	Macaca mulatta	37.35	4.00e-56	210.00
IUUC-Meu-056267	Macropus eugenii	32.62	2.00e-34	138.00
IUUC-Mor-057001	Magnaporthe oryzae	52.69	5.00e-85	305.00
IUUC-Mpo-057608	Magnaporthe poae	53.47	5.00e-51	192.00
IUUC-Mtr-057731	Medicago truncatula	46.21	1.00e-60	224.00
IUUC-Mla-059016	Melampsora laricipopulina	41.05	5.00e-43	165.00
IUUC-Mga-060178	Meleagris gallopavo	38.18	3.00e-49	186.00
IUUC-Mvi-060353	Microbotryum violaceum	35.24	5.00e-51	192.00
IUUC-Mmr-060738	Microcebus murinus	36.64	2.00e-55	207.00
IUUC-Mdo-062266	Monodelphis domestica	39.32	1.00e-43	167.00
IUUC-Mmu-063619	Mus musculus	36.64	2.00e-56	210.00
IUUC-Mac-065301	Musa acuminata	42.38	2.00e-63	234.00
IUUC-Mpu-066058	Mustela putorius furo	36.64	2.00e-55	207.00
IUUC-Mlu-067292	Myotis lucifugus	36.45	9.00e-56	208.00
IUUC-Nfi-068275	Neosartorya fischeri	78.38	2.00e-149	520.00
IUUC-Ncr-068713	Neurospora crassa	56.84	3.00e-103	366.00
IUUC-Nle-069013	Nomascus leucogenys	37.35	4.00e-56	209.00
IUUC-Opr-070628	Ochotona princeps	32.96	3.00e-47	180.00
IUUC-Ont-072688	Oreochromis niloticus	36.56	6.00e-55	205.00
IUUC-Oan-073004	Ornithorhynchus anatinus	40.95	8.00e-46	175.00
IUUC-Ocu-074303	Oryctolagus cuniculus	36.64	2.00e-54	204.00
IUUC-Oba-075002	Oryza barthii	37.78	4.00e-59	219.00
IUUC-Obr-076392	Oryza brachyantha	44.64	8.00e-60	222.00
IUUC-Ogl-077271	Oryza glaberrima	37.78	4.00e-59	219.00
IUUC-Ogu-078493	Oryza glumaepatula	45.32	6.00e-60	222.00
IUUC-Oin-080084	Oryza indica	45.32	6.00e-60	222.00
IUUC-Olo-080803	Oryza longistaminata	38.33	2.00e-60	224.00
IUUC-Ome-081146	Oryza meridionalis	38.33	3.00e-60	223.00
IUUC-Oni-082146	Oryza nivara	45.32	6.00e-60	222.00
IUUC-Opu-083633	Oryza punctata	45.32	6.00e-60	222.00
IUUC-Oru-084789	Oryza rufipogon	45.32	6.00e-60	222.00
IUUC-Osa-086196	Oryza sativa	45.32	6.00e-60	222.00
IUUC-Ola-087126	Oryzias latipes	37.16	1.00e-55	208.00
IUUC-Olu-087665	Ostreococcus lucimarinus	38.08	2.00e-52	197.00
IUUC-Oga-089140	Otolemur garnettii	34.17	4.00e-51	193.00
IUUC-Oar-090296	Ovis aries	36.34	8.00e-54	202.00
IUUC-Ptr-090566	Pan troglodytes	36.94	6.00e-56	209.00
IUUC-Pan-092052	Papio anubis	37.35	4.00e-56	209.00
IUUC-Psi-093723	Pelodiscus sinensis	38.55	4.00e-49	186.00
IUUC-Pma-094568	Petromyzon marinus	43.16	2.00e-46	177.00
IUUC-Pno-095120	Phaeosphaeria nodorum	57.72	6.00e-97	345.00
IUUC-Ppa-095761	Physcomitrella patens	44.80	3.00e-56	210.00
IUUC-Pfo-096210	Poecilia formosa	37.16	9.00e-56	208.00
IUUC-Pab-098463	Pongo abelii	36.94	1.00e-55	208.00
IUUC-Pop-099109	Populus trichocarpa	36.91	4.00e-54	202.00
IUUC-Pca-100108	Procavia capensis	40.86	3.00e-50	190.00
IUUC-Ppe-101176	Prunus persica	39.58	5.00e-54	202.00
IUUC-Pva-102629	Pteropus vampyrus	41.57	7.00e-52	195.00
IUUC-Pgr-103419	Puccinia graminis	33.71	4.00e-44	169.00
IUUC-Pte-104207	Pyrenophora teres	55.44	1.00e-50	190.00
IUUC-Pyt-104471	Pyrenophora triticirepentis	58.64	1.00e-97	347.00
IUUC-Rno-105579	Rattus norvegicus	36.18	4.00e-46	176.00
IUUC-Sha-106894	Sarcophilus harrisii	37.68	8.00e-49	185.00
IUUC-Sja-107732	Schizosaccharomyces japonicus	45.78	1.00e-77	281.00
IUUC-Spo-108371	Schizosaccharomyces pombe	46.32	3.00e-77	280.00
IUUC-Ssl-108467	Sclerotinia sclerotiorum	66.41	1.00e-97	347.00
IUUC-Smo-109396	Selaginella moellendorffii	40.29	4.00e-54	202.00
IUUC-Sit-110630	Setaria italica	44.80	4.00e-60	223.00
IUUC-Sly-110972	Solanum lycopersicum	39.16	5.00e-55	206.00
IUUC-Stu-112185	Solanum tuberosum	40.57	2.00e-62	230.00
IUUC-Sar-113294	Sorex araneus	31.84	2.00e-43	167.00
IUUC-Sbi-113951	Sorghum bicolor	46.38	1.00e-60	224.00
IUUC-Ssc-115501	Sus scrofa	35.74	3.00e-50	190.00
IUUC-Tgu-117152	Taeniopygia guttata	38.55	6.00e-49	185.00
IUUC-Tru-118388	Takifugu rubripes	36.25	3.00e-54	203.00
IUUC-Tsy-119109	Tarsius syrichta	36.64	3.00e-55	206.00
IUUC-Tni-120048	Tetraodon nigroviridis	36.86	5.00e-55	206.00
IUUC-Tca-121750	Theobroma cacao	42.51	1.00e-62	231.00
IUUC-Tre-122130	Trichoderma reesei	58.31	3.00e-99	353.00
IUUC-Tvi-122284	Trichoderma virens	58.70	5.00e-92	328.00
IUUC-Tae-124183	Triticum aestivum	43.12	8.00e-56	209.00
IUUC-Tur-126366	Triticum urartu	34.33	2.00e-36	144.00
IUUC-Tme-127187	Tuber melanosporum	56.71	2.00e-105	374.00
IUUC-Tbe-127705	Tupaia belangeri	33.71	4.00e-33	133.00
IUUC-Ttr-128867	Tursiops truncatus	39.73	8.00e-41	159.00
IUUC-Vda-129912	Verticillium dahliae	52.41	2.00e-83	300.00
IUUC-Vpa-130552	Vicugna pacos	39.66	9.00e-45	172.00
IUUC-Vvi-130881	Vitis vinifera	39.71	3.00e-56	210.00
IUUC-Xtr-131934	Xenopus tropicalis	36.86	1.00e-54	204.00
IUUC-Xma-133312	Xiphophorus maculatus	37.16	9.00e-56	208.00
IUUC-Yli-134487	Yarrowia lipolytica	40.73	6.00e-66	242.00
IUUC-Zma-135639	Zea mays	42.09	6.00e-55	206.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence