iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-001338

Ensembl Protein ID

ENSAMEP00000014918.1

UniProt Accession

G1M6E8; G1M6E8_AILME

Genbank Protein ID

ENSAMEP00000014918

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

ACTA01010601

Gene Name

ING4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000014135.1	ENSAMET00000015532.1	ENSAMEP00000014918.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	7.40e-10	39.0	196	243

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C++ + +e  ++ C++  C+ ewfH+aC++l+   ++p+ + w+Cp+C++
   Q: 196  TYC-LCHQVSYGE--MIGCDNpdCSiEWFHFACVGLT---TKPRGK-WFCPRCSQ 243
           69*.*******99..********999***********...899996.******97 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MAAGMYLEHY LDSIENLPFE LQRNFQLMRD LDQRTEDLKA EIDKLATEYM SSARSLSSEE 60
KLALLKQIQE AYGKCKEFGD DKVQLAMQTY EMVDKHIRRL DTDLARFEAD LKEKQIESSD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGCGG GGATGTATTT GGAACATTAT CTGGACAGTA AGAGCAGGCT GGAGGAGGGG 60
GTCAGGGGTC ATAGAGTGGC GGGGGGGATC AGGGCTGAGG AGCCGTACGG CCCCGAAGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028647--ING4
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0000123--C:histone acetyltransferase complex
GO:0003713--F:transcription coactivator activity
GO:0008270--F:zinc ion binding
GO:0006915--P:apoptotic process
GO:0007050--P:cell cycle arrest
GO:0006978--P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0006260--P:DNA replication
GO:0043966--P:histone H3 acetylation
GO:0043983--P:histone H4-K12 acetylation
GO:0043981--P:histone H4-K5 acetylation
GO:0043982--P:histone H4-K8 acetylation
GO:0008285--P:negative regulation of cell proliferation
GO:0045926--P:negative regulation of growth
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0043065--P:positive regulation of apoptotic process

KEGG

aml:100477329

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004097	Anas platyrhynchos	90.73	3.00e-117	414.00
IUUC-Aca-004593	Anolis carolinensis	93.17	5.00e-123	433.00
IUUC-Ame-011133	Astyanax mexicanus	79.68	2.00e-116	411.00
IUUC-Bta-012699	Bos taurus	98.79	4.00e-128	450.00
IUUC-Bdi-014504	Brachypodium distachyon	35.60	7.00e-40	157.00
IUUC-Bol-015245	Brassica oleracea	31.45	5.00e-30	124.00
IUUC-Bra-017027	Brassica rapa	31.85	1.00e-30	126.00
IUUC-Cel-018700	Caenorhabditis elegans	47.27	9.00e-08	52.80
IUUC-Cja-019988	Callithrix jacchus	96.39	3.00e-119	420.00
IUUC-Cfa-021282	Canis familiaris	96.39	3.00e-119	420.00
IUUC-Cpo-022011	Cavia porcellus	96.39	1.00e-129	454.00
IUUC-Cre-022920	Chlamydomonas reinhardtii	31.35	6.00e-29	120.00
IUUC-Csa-023203	Chlorocebus sabaeus	96.39	3.00e-119	420.00
IUUC-Cin-025479	Ciona intestinalis	62.87	2.00e-80	291.00
IUUC-Csv-026288	Ciona savignyi	55.43	4.00e-75	274.00
IUUC-Dre-028264	Danio rerio	79.28	7.00e-115	405.00
IUUC-Dno-029766	Dasypus novemcinctus	93.55	7.00e-113	399.00
IUUC-Dor-031136	Dipodomys ordii	81.78	9.00e-98	349.00
IUUC-Dme-032200	Drosophila melanogaster	74.19	2.00e-40	159.00
IUUC-Eca-033565	Equus caballus	96.39	1.00e-129	454.00
IUUC-Eeu-034948	Erinaceus europaeus	80.89	2.00e-100	357.00
IUUC-Fca-036368	Felis catus	96.79	9.00e-120	422.00
IUUC-Fal-037120	Ficedula albicollis	90.32	5.00e-116	409.00
IUUC-Gmo-038982	Gadus morhua	81.20	1.00e-114	405.00
IUUC-Gga-040771	Gallus gallus	93.17	5.00e-123	433.00
IUUC-Gac-042184	Gasterosteus aculeatus	80.89	2.00e-111	394.00
IUUC-Gma-044339	Glycine max	29.48	9.00e-34	136.00
IUUC-Ggo-045559	Gorilla gorilla	96.39	3.00e-119	420.00
IUUC-Hsa-046852	Homo sapiens	96.39	3.00e-119	420.00
IUUC-Hvu-047046	Hordeum vulgare	35.71	7.00e-37	147.00
IUUC-Itr-047978	Ictidomys tridecemlineatus	95.98	3.00e-129	453.00
IUUC-Kpa-049229	Komagataella pastoris	59.18	1.00e-16	79.30
IUUC-Lpe-050822	Leersia perrieri	34.80	2.00e-38	152.00
IUUC-Laf-054057	Loxodonta africana	96.79	9.00e-120	422.00
IUUC-Mcc-055212	Macaca mulatta	91.63	9.00e-115	405.00
IUUC-Meu-056511	Macropus eugenii	93.22	3.00e-120	424.00
IUUC-Mga-059967	Meleagris gallopavo	91.09	8.00e-117	412.00
IUUC-Mmr-060843	Microcebus murinus	98.39	4.00e-127	446.00
IUUC-Mdo-062357	Monodelphis domestica	95.98	7.00e-129	452.00
IUUC-Mmu-064093	Mus musculus	96.39	1.00e-129	454.00
IUUC-Mac-064625	Musa acuminata	35.27	2.00e-37	148.00
IUUC-Mpu-066923	Mustela putorius furo	83.13	8.00e-97	345.00
IUUC-Mlu-067754	Myotis lucifugus	88.89	2.00e-117	414.00
IUUC-Nle-069062	Nomascus leucogenys	96.39	3.00e-119	420.00
IUUC-Opr-070207	Ochotona princeps	89.41	1.00e-110	391.00
IUUC-Ont-072446	Oreochromis niloticus	81.60	3.00e-113	400.00
IUUC-Ocu-074235	Oryctolagus cuniculus	96.39	3.00e-119	420.00
IUUC-Obr-076266	Oryza brachyantha	34.80	7.00e-38	150.00
IUUC-Oin-079049	Oryza indica	33.47	2.00e-36	145.00
IUUC-Ome-081291	Oryza meridionalis	35.46	5.00e-37	147.00
IUUC-Oni-082218	Oryza nivara	33.47	2.00e-36	145.00
IUUC-Opu-084171	Oryza punctata	35.25	5.00e-37	147.00
IUUC-Osa-085563	Oryza sativa	35.46	5.00e-37	147.00
IUUC-Ola-086429	Oryzias latipes	77.20	6.00e-105	373.00
IUUC-Olu-087851	Ostreococcus lucimarinus	34.16	3.00e-20	91.30
IUUC-Oga-089123	Otolemur garnettii	96.79	9.00e-120	422.00
IUUC-Oar-089524	Ovis aries	98.79	4.00e-128	450.00
IUUC-Ptr-090908	Pan troglodytes	95.98	1.00e-118	419.00
IUUC-Pan-092837	Papio anubis	99.60	6.00e-128	449.00
IUUC-Psi-093828	Pelodiscus sinensis	93.13	2.00e-112	397.00
IUUC-Ppa-096009	Physcomitrella patens	33.98	9.00e-34	136.00
IUUC-Pfo-096617	Poecilia formosa	81.20	2.00e-113	401.00
IUUC-Pab-097978	Pongo abelii	95.76	1.00e-108	385.00
IUUC-Pop-099415	Populus trichocarpa	73.68	2.00e-26	112.00
IUUC-Pca-100475	Procavia capensis	65.86	2.00e-84	304.00
IUUC-Ppe-101441	Prunus persica	32.94	1.00e-36	146.00
IUUC-Pva-102325	Pteropus vampyrus	96.39	1.00e-129	454.00
IUUC-Rno-105178	Rattus norvegicus	98.39	6.00e-137	479.00
IUUC-Sha-106773	Sarcophilus harrisii	95.98	6.00e-129	453.00
IUUC-Smo-109441	Selaginella moellendorffii	32.16	2.00e-39	154.00
IUUC-Sit-109827	Setaria italica	35.60	1.00e-36	146.00
IUUC-Sly-111750	Solanum lycopersicum	34.66	4.00e-36	144.00
IUUC-Stu-112250	Solanum tuberosum	34.66	4.00e-36	144.00
IUUC-Sbi-114826	Sorghum bicolor	36.00	2.00e-37	149.00
IUUC-Sre-115124	Sporisorium reilianum	58.21	2.00e-22	100.00
IUUC-Ssc-115797	Sus scrofa	89.84	7.00e-104	369.00
IUUC-Tgu-117270	Taeniopygia guttata	93.17	5.00e-123	433.00
IUUC-Tru-118253	Takifugu rubripes	80.88	3.00e-114	404.00
IUUC-Tca-121597	Theobroma cacao	69.84	3.00e-28	118.00
IUUC-Tae-123043	Triticum aestivum	35.04	4.00e-38	151.00
IUUC-Tbe-127558	Tupaia belangeri	100.00	2.00e-128	451.00
IUUC-Ttr-128300	Tursiops truncatus	100.00	1.00e-65	242.00
IUUC-Uma-129581	Ustilago maydis	57.63	3.00e-21	97.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence