iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003773

Ensembl Protein ID

ENSAPLP00000003421.1

UniProt Accession

U3I850; U3I850_ANAPL

Genbank Protein ID

ENSAPLP00000003421

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01126099

Gene Name

USP48

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000003841.1	ENSAPLT00000004022.1	ENSAPLP00000003421.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.40e-73	247.7	4	334
ULD/UDP/UBQ/UBQ_Other	5.50e-11	41.9	868	926

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenp........kepkgellkslqklfeelwkskkkavsprellkalkkea 81
           +Gl+Nlg+tCY+N  LQ+ +   elr++l    +++++e           + + ++++++lq lf+ l++sk+++++p+ ++kal+   
   Q: 4    VGLTNLGATCYVNTFLQMWFLNLELRQALYL-CPSTCSEHTAgegvpkdkDYEPQTICEHLQYLFALLQNSKRRYIDPSGFVKALG--- 88
           6*****************************9.66666655445555555467778******************************9... PP
   S: 82   eefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfl 170
             +++ +qqDaqEf + +++ le++l                       +++k+   ++++++ F g++   ++c++c+++s+  ++f+
   Q: 89   --LDTGQQQDAQEFSKLFMSLLEDTL-----------------------SKQKNPDVRNIVQKQFCGEYAYVTVCNQCGRESKLVSKFY 152
           ..78899*******************.......................457889999******************************* PP
   S: 171  dlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleL 259
           +l+l+++g++     +l+dc+ +f kee+leg+n+y+ce+c++kq+a++k++l +lP +L l+L+Rf f++++++++k+n+++ f + L
   Q: 153  ELELNIQGHK-----QLTDCITEFLKEEKLEGDNRYFCETCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNTYIGFSELL 236
           **********.....9**********************************************************************99* PP
   S: 260  dlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetg................... 327
           d++pf+++++      + YeL+av++H G s+ sGHY+a+vk+ + + W++f+D+ +++++ ++ +   +                   
   Q: 237  DMEPFMEQKSG----VYVYELSAVLIHRGvSAYSGHYIAHVKDPQTGeWYKFNDEDIEKMEGKKLQLGIEedlaepsksqtrkpkcgkg 321
           *******9543....69**************************55555************9999998665999**************** PP
   S: 328  ....staYvlfYk 336
               ++aY+l+Y+
   Q: 322  thcsRNAYMLVYR 334
           ************8 PP

ULD/UDP/UBQ/UBQ_Other

   S: 17   vnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglkdgstihllekks 74
           v+   t +eLK +i +++++ p +q+L ++GkiL +d  tL+++g+ ++s+i+l  +++
   Q: 868  VSANQTLKELKIQIMHAFSVAPFDQNLSIDGKILsDDTATLGSLGVIPESVILLKADEP 926
           88899************************************************988775 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

NAFVGLTNLG ATCYVNTFLQ MWFLNLELRQ ALYLCPSTCS EHTAGEGVPK DKDYEPQTIC 60
EHLQYLFALL QNSKRRYIDP SGFVKALGLD TGQQQDAQEF SKLFMSLLED TLSKQKNPDV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AACGCGTTCG TGGGCTTAAC GAACCTCGGC GCCACGTGCT ACGTGAACAC TTTCTTGCAG 60
ATGTGGTTTC TCAACTTGGA GCTCCGGCAG GCCCTCTACT TGTGTCCCAG TACCTGCAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR033841--USP48
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS50053--UBIQUITIN_2
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

SMART

SM00695--DUSP

Gene Ontology

GO:0005829--C:cytosol
GO:0005739--C:mitochondrion
GO:0005654--C:nucleoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000130	Aegilops tauschii	28.98	5.00e-78	286.00
IUUC-Aml-001357	Ailuropoda melanoleuca	87.54	0.00e+00	1682.00
IUUC-Atr-002976	Amborella trichopoda	26.79	2.00e-75	277.00
IUUC-Aca-004466	Anolis carolinensis	84.73	0.00e+00	829.00
IUUC-Aly-006249	Arabidopsis lyrata	30.77	7.00e-67	248.00
IUUC-Ath-006700	Arabidopsis thaliana	28.16	7.00e-76	278.00
IUUC-Ame-011554	Astyanax mexicanus	67.01	0.00e+00	1281.00
IUUC-Bta-012573	Bos taurus	87.36	0.00e+00	1682.00
IUUC-Bdi-014149	Brachypodium distachyon	33.70	1.00e-79	291.00
IUUC-Bol-016289	Brassica oleracea	30.30	4.00e-78	286.00
IUUC-Bra-017205	Brassica rapa	29.46	6.00e-70	258.00
IUUC-Cel-018662	Caenorhabditis elegans	29.83	1.00e-28	122.00
IUUC-Cja-019991	Callithrix jacchus	86.58	0.00e+00	1681.00
IUUC-Cfa-020294	Canis familiaris	87.75	0.00e+00	1710.00
IUUC-Cpo-021706	Cavia porcellus	86.18	0.00e+00	1673.00
IUUC-Cre-022636	Chlamydomonas reinhardtii	33.07	7.00e-42	167.00
IUUC-Csa-023931	Chlorocebus sabaeus	87.54	0.00e+00	1693.00
IUUC-Cho-024566	Choloepus hoffmanni	89.89	5.00e-144	504.00
IUUC-Cin-025307	Ciona intestinalis	53.95	1.00e-60	225.00
IUUC-Csv-026006	Ciona savignyi	36.66	1.00e-133	470.00
IUUC-Cne-027065	Cryptococcus neoformans	27.03	9.00e-63	235.00
IUUC-Dre-027624	Danio rerio	68.14	0.00e+00	1332.00
IUUC-Dno-029633	Dasypus novemcinctus	87.78	0.00e+00	1188.00
IUUC-Dor-030809	Dipodomys ordii	65.31	0.00e+00	913.00
IUUC-Ete-032818	Echinops telfairi	82.83	0.00e+00	786.00
IUUC-Eca-033692	Equus caballus	88.17	0.00e+00	1704.00
IUUC-Eeu-035185	Erinaceus europaeus	66.85	0.00e+00	698.00
IUUC-Fca-035676	Felis catus	87.43	0.00e+00	1706.00
IUUC-Fal-036913	Ficedula albicollis	95.39	0.00e+00	1827.00
IUUC-Gmo-038532	Gadus morhua	63.73	0.00e+00	1236.00
IUUC-Gga-041041	Gallus gallus	96.65	0.00e+00	1842.00
IUUC-Gac-042570	Gasterosteus aculeatus	65.40	0.00e+00	1283.00
IUUC-Gma-044136	Glycine max	30.88	9.00e-89	321.00
IUUC-Ggo-045367	Gorilla gorilla	83.09	0.00e+00	1570.00
IUUC-Hsa-046019	Homo sapiens	87.64	0.00e+00	1693.00
IUUC-Hvu-047303	Hordeum vulgare	35.23	4.00e-62	231.00
IUUC-Itr-048319	Ictidomys tridecemlineatus	85.52	0.00e+00	1668.00
IUUC-Lch-049989	Latimeria chalumnae	75.65	0.00e+00	1473.00
IUUC-Lpe-051612	Leersia perrieri	34.53	1.00e-77	284.00
IUUC-Loc-052756	Lepisosteus oculatus	69.51	0.00e+00	1375.00
IUUC-Laf-054043	Loxodonta africana	86.33	0.00e+00	1684.00
IUUC-Mcc-054986	Macaca mulatta	86.08	0.00e+00	1674.00
IUUC-Meu-056228	Macropus eugenii	73.01	0.00e+00	805.00
IUUC-Mtr-058610	Medicago truncatula	30.83	1.00e-78	288.00
IUUC-Mga-059896	Meleagris gallopavo	95.62	0.00e+00	1816.00
IUUC-Mvi-060269	Microbotryum violaceum	39.00	1.00e-57	218.00
IUUC-Mmr-060887	Microcebus murinus	87.54	0.00e+00	1689.00
IUUC-Mdo-062506	Monodelphis domestica	88.27	0.00e+00	1711.00
IUUC-Mmu-063642	Mus musculus	83.56	0.00e+00	1641.00
IUUC-Mac-064896	Musa acuminata	32.98	1.00e-76	281.00
IUUC-Mpu-066194	Mustela putorius furo	87.75	0.00e+00	1690.00
IUUC-Mlu-067233	Myotis lucifugus	87.03	0.00e+00	1682.00
IUUC-Nle-069052	Nomascus leucogenys	86.45	0.00e+00	1678.00
IUUC-Opr-070890	Ochotona princeps	86.06	0.00e+00	968.00
IUUC-Ont-071450	Oreochromis niloticus	63.89	0.00e+00	1231.00
IUUC-Oan-073252	Ornithorhynchus anatinus	86.59	0.00e+00	1010.00
IUUC-Ocu-073796	Oryctolagus cuniculus	87.38	0.00e+00	1597.00
IUUC-Oba-075563	Oryza barthii	34.51	1.00e-79	291.00
IUUC-Obr-076394	Oryza brachyantha	33.81	7.00e-79	288.00
IUUC-Ogl-077339	Oryza glaberrima	45.16	1.00e-39	155.00
IUUC-Ogu-079007	Oryza glumaepatula	36.71	6.00e-74	272.00
IUUC-Oin-079997	Oryza indica	34.51	7.00e-80	291.00
IUUC-Olo-080364	Oryza longistaminata	34.51	1.00e-79	291.00
IUUC-Ome-081165	Oryza meridionalis	35.98	5.00e-74	272.00
IUUC-Oni-083026	Oryza nivara	34.51	7.00e-80	292.00
IUUC-Opu-083284	Oryza punctata	37.73	1.00e-74	274.00
IUUC-Oru-084797	Oryza rufipogon	34.51	9.00e-80	291.00
IUUC-Osa-086221	Oryza sativa	45.16	1.00e-39	155.00
IUUC-Ola-086568	Oryzias latipes	66.10	0.00e+00	1294.00
IUUC-Oga-088687	Otolemur garnettii	86.26	0.00e+00	1675.00
IUUC-Oar-090345	Ovis aries	87.47	0.00e+00	1686.00
IUUC-Ptr-090734	Pan troglodytes	87.75	0.00e+00	1695.00
IUUC-Pan-091704	Papio anubis	84.24	0.00e+00	1608.00
IUUC-Psi-092937	Pelodiscus sinensis	93.57	0.00e+00	1731.00
IUUC-Ppa-095808	Physcomitrella patens	28.97	3.00e-66	247.00
IUUC-Pab-098129	Pongo abelii	87.75	0.00e+00	1696.00
IUUC-Pop-099494	Populus trichocarpa	33.27	7.00e-76	278.00
IUUC-Pca-100647	Procavia capensis	91.43	5.00e-136	478.00
IUUC-Ppe-102091	Prunus persica	29.55	3.00e-77	283.00
IUUC-Pva-102719	Pteropus vampyrus	87.54	0.00e+00	1682.00
IUUC-Rno-105363	Rattus norvegicus	85.45	0.00e+00	1666.00
IUUC-Sha-107620	Sarcophilus harrisii	85.64	0.00e+00	1672.00
IUUC-Smo-109487	Selaginella moellendorffii	27.96	2.00e-78	287.00
IUUC-Sit-110683	Setaria italica	30.48	1.00e-78	288.00
IUUC-Sly-111377	Solanum lycopersicum	32.75	3.00e-74	273.00
IUUC-Stu-111969	Solanum tuberosum	33.76	5.00e-65	241.00
IUUC-Sar-113099	Sorex araneus	87.58	0.00e+00	1592.00
IUUC-Sbi-113833	Sorghum bicolor	43.34	2.00e-56	212.00
IUUC-Ssc-115279	Sus scrofa	80.50	0.00e+00	1201.00
IUUC-Tgu-117519	Taeniopygia guttata	91.98	0.00e+00	1739.00
IUUC-Tru-117651	Takifugu rubripes	65.86	0.00e+00	1282.00
IUUC-Tsy-119201	Tarsius syrichta	85.03	0.00e+00	1583.00
IUUC-Tni-120840	Tetraodon nigroviridis	67.11	0.00e+00	1301.00
IUUC-Tca-121674	Theobroma cacao	28.76	2.00e-82	300.00
IUUC-Tae-125247	Triticum aestivum	29.08	3.00e-78	287.00
IUUC-Tur-126599	Triticum urartu	29.37	4.00e-77	283.00
IUUC-Tbe-127782	Tupaia belangeri	76.58	0.00e+00	1404.00
IUUC-Ttr-128312	Tursiops truncatus	86.39	0.00e+00	1660.00
IUUC-Vpa-130348	Vicugna pacos	87.54	0.00e+00	1688.00
IUUC-Vvi-131353	Vitis vinifera	33.62	2.00e-80	293.00
IUUC-Xtr-132172	Xenopus tropicalis	69.76	0.00e+00	1254.00
IUUC-Xma-133263	Xiphophorus maculatus	66.70	0.00e+00	1253.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence