iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-007127

UUCD1 version

UUC-ArT-01530

Ensembl Protein ID

AT5G48170.1

UniProt Accession

Q9LUB6; SNE_ARATH

Genbank Protein ID

BAA96997.1; AED95628.1; AAS65942.1; AAS88781.1

Protein Name

F-box protein SNE; Protein SNEEZY; Sleepy protein 2

Genbank Nucleotide ID

AB023039; CP002688; BT011771; BT012391

Gene Name

SNE; SLY2; At5g48170; MIF21.6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT5G48170	AT5G48170.1	AT5G48170.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	PINA	HINT	Mentha
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 adaptor/Cullin RING/SCF/F-box	F-box	21163960; 15308775

Classification

Family	E-value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	2.50e-05	25.2	32	70

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 108  eeilveilklldkeellraarvcrrwqelasqkalwktv 146
           +++lveil++ld+++l++aa+vcr w+ +a+++++w+++
   Q: 32   HDVLVEILRRLDGSSLCSAACVCRLWSAVARNDSIWEEL 70
           689****************************9****986 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Essential component of a SCF-type E3 ligase complex that positively regulates the gibberellin signaling pathway. Upon gibberellin treatment, such complex probably mediates the ubiquitination and subsequent degradation of DELLA proteins (GAI, RGA and RGL2), some repressors of the gibberellin pathway, leading to activate the pathway. Can partially complement the absence of GID2/SLY1.

Protein Sequence
(Fasta)

MSSEKRVGMV EKSNNKRQRV NQVPVFSIND HHDVLVEILR RLDGSSLCSA ACVCRLWSAV 60
ARNDSIWEEL CFRQVSPRPS LSLRSVVSAL GGYRCLYFLC IRPVLARLPK LLWTRDQLQL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAACATTAAA TTTTTATTCT TTTTACAGAT TGAATAAAAC ATCACTCCTC CTCTCTCTCT 60
GCTTCTCACT TACACACAAT ATACACACAT ATAAATATAG AGTTATATGT GCCCGTGTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0939--Gibberellin signaling pathway
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR001810--F-box_dom

Pfam

PF12937--F-box-like

SMART

SM00256--FBOX

Gene Ontology

GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0009740--P:gibberellic acid mediated signaling pathway
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0009937--P:regulation of gibberellic acid mediated signaling pathway
GO:0048831--P:regulation of shoot system development

KEGG

ath:AT5G48170

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002846	Amborella trichopoda	38.56	7.00e-25	105.00
IUUC-Apl-003195	Anas platyrhynchos	41.46	5.00e-04	36.20
IUUC-Aca-004788	Anolis carolinensis	39.02	8.00e-04	35.00
IUUC-Aly-005539	Arabidopsis lyrata	95.48	1.00e-83	300.00
IUUC-Bdi-014290	Brachypodium distachyon	60.38	2.00e-15	74.30
IUUC-Bol-015233	Brassica oleracea	93.55	1.00e-82	297.00
IUUC-Bra-017984	Brassica rapa	94.84	3.00e-84	302.00
IUUC-Cin-025781	Ciona intestinalis	34.04	3.00e-04	39.70
IUUC-Dor-030194	Dipodomys ordii	37.18	3.00e-05	40.40
IUUC-Gac-041831	Gasterosteus aculeatus	41.46	3.00e-04	37.00
IUUC-Gma-043632	Glycine max	57.86	3.00e-38	149.00
IUUC-Lpe-050816	Leersia perrieri	44.08	2.00e-06	45.10
IUUC-Loc-052597	Lepisosteus oculatus	41.46	9.00e-05	38.90
IUUC-Laf-054453	Loxodonta africana	48.78	2.00e-05	40.80
IUUC-Mtr-057946	Medicago truncatula	57.25	5.00e-33	132.00
IUUC-Ont-071264	Oreochromis niloticus	26.09	1.00e-03	37.40
IUUC-Ogl-077474	Oryza glaberrima	50.00	4.00e-07	46.60
IUUC-Ogu-079029	Oryza glumaepatula	50.00	4.00e-07	46.60
IUUC-Oin-080121	Oryza indica	50.00	4.00e-07	46.60
IUUC-Ome-081968	Oryza meridionalis	65.31	2.00e-05	39.30
IUUC-Oni-082552	Oryza nivara	50.00	4.00e-07	46.60
IUUC-Opu-083746	Oryza punctata	50.35	2.00e-09	54.70
IUUC-Oru-084658	Oryza rufipogon	50.00	4.00e-07	46.60
IUUC-Osa-086295	Oryza sativa	50.00	4.00e-07	46.60
IUUC-Olu-087621	Ostreococcus lucimarinus	31.34	3.00e-04	40.40
IUUC-Pop-099566	Populus trichocarpa	61.81	3.00e-36	143.00
IUUC-Pca-100414	Procavia capensis	41.46	7.00e-04	35.40
IUUC-Ppe-102106	Prunus persica	62.10	1.00e-33	134.00
IUUC-Sly-111364	Solanum lycopersicum	57.72	4.00e-34	136.00
IUUC-Stu-112502	Solanum tuberosum	57.72	4.00e-34	136.00
IUUC-Sbi-114231	Sorghum bicolor	65.31	3.00e-05	41.20
IUUC-Tae-124891	Triticum aestivum	62.26	2.00e-15	74.70
IUUC-Vvi-130926	Vitis vinifera	56.49	9.00e-36	142.00
IUUC-Xma-133035	Xiphophorus maculatus	32.39	2.00e-04	38.90

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence