iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003305

Ensembl Protein ID

ENSAPLP00000003200.1

UniProt Accession

U3I7H9; U3I7H9_ANAPL

Genbank Protein ID

ENSAPLP00000003200

Protein Name

Katanin p80 WD40 repeat-containing subunit B1; p80 katanin

Genbank Nucleotide ID

ADON01075981

Gene Name

KATNB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000003613.1	ENSAPLT00000003799.1	ENSAPLP00000003200.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.50e-43	143.9	145	180
UBD/Beta-Prp	6.60e-62	209.1	15	229

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           gHt  v+cl+f +d + l+s++dD+t+k+WDl  g+
   Q: 145  GHTQAVRCLRFsPDgKWLASAADDHTVKLWDLAAGK 180
           8***********999****************98775 PP

UBD/Beta-Prp

   S: 47   slsgheaevtavkfspdgk.ilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetls 134
           ++  h++ v+++ + +++  +l+tg++D  +++w+++++ c+++l+gh++ + sl+++ + + +v+Gs+   irvwdle  + l+ tl 
   Q: 15   EITAHSSNVSSLVLAKSSGrLLATGGDDCRVNIWSVNKPNCIMSLTGHTSPIESLQININEELIVAGSQSGSIRVWDLEAAKILR-TLF 102
           5667888898887765544499**************************************************************9.*** PP
   S: 135  ghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtd 223
           gh++ ++++ +hp+g+ ++sGslD+ ++lWd++++ ++ + +g ht++v++l f+++gk l+s+++d tvklwdl +g+++ +++gh  
   Q: 103  GHKANICSLDFHPFGSFVASGSLDTNIKLWDVRRKGCVFRYKG-HTQAVRCLRFSPDGKWLASAADDHTVKLWDLAAGKMMFEFTGHGG 190
           *****************************************99.********************************************* PP
   S: 224  nvksvrfspnderlvsgssDgsiriWdlrsgdllktlql 262
           +v++v+f+pn+ +l+sgssD+++r+Wdl++ +++++++ 
   Q: 191  PVNVVEFHPNEYLLASGSSDRTVRFWDLEKFQVVSCIEE 229
           *****************************9999998876 PP

Organism

Anas platyrhynchos

Functional Description
(View)

Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.

Protein Sequence
(Fasta)

QKLLPKTLVD FKAEEITAHS SNVSSLVLAK SSGRLLATGG DDCRVNIWSV NKPNCIMSLT 60
GHTSPIESLQ ININEELIVA GSQSGSIRVW DLEAAKILRT LFGHKANICS LDFHPFGSFV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGAAGCTCC TGCCAAAAAC TTTGGTGGAT TTTAAAGTCC ATTATAAAAA TAGATATCTA 60
TGCAAAAATG CTCTTTTGGC TTCTCTTTTG TCCCCAACAT TGTTTCCATA TGAGAAGGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-0498--Mitosis
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR026962--Katanin_bsu1
IPR028021--Katanin_C-terminal
IPR023302--Pept_S9A_N
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13925--Katanin_con80
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030424--C:axon
GO:0005813--C:centrosome
GO:0005829--C:cytosol
GO:0008352--C:katanin complex
GO:0005874--C:microtubule
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0000922--C:spindle pole
GO:0008568--F:microtubule-severing ATPase activity
GO:0051301--P:cell division
GO:0051013--P:microtubule severing
GO:0007067--P:mitotic nuclear division
GO:0007026--P:negative regulation of microtubule depolymerization
GO:0031117--P:positive regulation of microtubule depolymerization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000954	Aegilops tauschii	46.58	7.00e-84	305.00
IUUC-Aml-002187	Ailuropoda melanoleuca	76.27	0.00e+00	951.00
IUUC-Atr-002899	Amborella trichopoda	54.61	6.00e-103	368.00
IUUC-Aca-004635	Anolis carolinensis	80.41	0.00e+00	1014.00
IUUC-Aly-005711	Arabidopsis lyrata	51.86	3.00e-100	359.00
IUUC-Ath-007606	Arabidopsis thaliana	51.86	2.00e-100	359.00
IUUC-Ame-010870	Astyanax mexicanus	57.66	2.00e-101	361.00
IUUC-Bta-012527	Bos taurus	77.26	0.00e+00	1008.00
IUUC-Bdi-014652	Brachypodium distachyon	51.53	1.00e-100	360.00
IUUC-Bol-015242	Brassica oleracea	50.17	3.00e-98	352.00
IUUC-Bra-017390	Brassica rapa	50.51	1.00e-98	353.00
IUUC-Cja-019706	Callithrix jacchus	75.95	0.00e+00	930.00
IUUC-Cfa-020139	Canis familiaris	62.35	0.00e+00	632.00
IUUC-Cpo-021710	Cavia porcellus	77.13	0.00e+00	993.00
IUUC-Cre-022746	Chlamydomonas reinhardtii	39.33	4.00e-68	252.00
IUUC-Csa-023546	Chlorocebus sabaeus	77.71	0.00e+00	910.00
IUUC-Cin-025156	Ciona intestinalis	39.31	3.00e-148	518.00
IUUC-Csv-025962	Ciona savignyi	46.69	3.00e-83	301.00
IUUC-Dre-028215	Danio rerio	60.85	0.00e+00	845.00
IUUC-Dno-029314	Dasypus novemcinctus	76.54	0.00e+00	950.00
IUUC-Dor-030482	Dipodomys ordii	76.68	0.00e+00	1016.00
IUUC-Dme-032188	Drosophila melanogaster	38.61	8.00e-60	224.00
IUUC-Eca-034143	Equus caballus	76.24	0.00e+00	988.00
IUUC-Fca-035924	Felis catus	76.24	0.00e+00	963.00
IUUC-Fal-037387	Ficedula albicollis	84.55	0.00e+00	1109.00
IUUC-Gmo-038692	Gadus morhua	63.81	4.00e-150	524.00
IUUC-Gga-040597	Gallus gallus	84.96	0.00e+00	1156.00
IUUC-Gac-042004	Gasterosteus aculeatus	65.93	8.00e-162	563.00
IUUC-Gma-044134	Glycine max	52.20	1.00e-98	353.00
IUUC-Ggo-044761	Gorilla gorilla	77.71	0.00e+00	937.00
IUUC-Hsa-045698	Homo sapiens	78.30	0.00e+00	958.00
IUUC-Hvu-047649	Hordeum vulgare	50.85	8.00e-100	358.00
IUUC-Itr-048697	Ictidomys tridecemlineatus	77.13	0.00e+00	969.00
IUUC-Lch-049674	Latimeria chalumnae	69.96	0.00e+00	643.00
IUUC-Lpe-051554	Leersia perrieri	52.20	3.00e-102	365.00
IUUC-Loc-052623	Lepisosteus oculatus	66.91	0.00e+00	902.00
IUUC-Laf-054587	Loxodonta africana	76.82	0.00e+00	995.00
IUUC-Mcc-055851	Macaca mulatta	77.71	0.00e+00	937.00
IUUC-Meu-056704	Macropus eugenii	78.69	0.00e+00	1072.00
IUUC-Mtr-058053	Medicago truncatula	51.86	1.00e-101	363.00
IUUC-Mga-059608	Meleagris gallopavo	85.38	0.00e+00	1160.00
IUUC-Mmr-061154	Microcebus murinus	76.24	0.00e+00	954.00
IUUC-Mdo-062365	Monodelphis domestica	74.49	0.00e+00	1004.00
IUUC-Mmu-063754	Mus musculus	77.29	0.00e+00	976.00
IUUC-Mac-064439	Musa acuminata	48.93	5.00e-100	358.00
IUUC-Mpu-066245	Mustela putorius furo	79.57	0.00e+00	645.00
IUUC-Mlu-067692	Myotis lucifugus	77.42	0.00e+00	987.00
IUUC-Nle-070051	Nomascus leucogenys	76.43	0.00e+00	929.00
IUUC-Opr-070855	Ochotona princeps	76.09	0.00e+00	972.00
IUUC-Ont-071883	Oreochromis niloticus	60.20	0.00e+00	835.00
IUUC-Oan-073293	Ornithorhynchus anatinus	77.26	0.00e+00	934.00
IUUC-Ocu-074644	Oryctolagus cuniculus	77.11	0.00e+00	987.00
IUUC-Oba-075448	Oryza barthii	52.29	2.00e-103	369.00
IUUC-Obr-076385	Oryza brachyantha	51.53	1.00e-101	363.00
IUUC-Ogl-077427	Oryza glaberrima	52.54	7.00e-103	368.00
IUUC-Ogu-078062	Oryza glumaepatula	47.96	3.00e-93	336.00
IUUC-Oin-079811	Oryza indica	51.32	1.00e-102	367.00
IUUC-Olo-080245	Oryza longistaminata	51.32	1.00e-102	367.00
IUUC-Ome-081239	Oryza meridionalis	52.92	2.00e-101	363.00
IUUC-Oni-082640	Oryza nivara	52.29	2.00e-103	369.00
IUUC-Opu-083748	Oryza punctata	52.20	3.00e-102	365.00
IUUC-Oru-084609	Oryza rufipogon	52.29	2.00e-103	369.00
IUUC-Osa-085801	Oryza sativa	47.12	3.00e-93	335.00
IUUC-Ola-087483	Oryzias latipes	54.16	7.00e-180	623.00
IUUC-Oga-087964	Otolemur garnettii	77.15	0.00e+00	1003.00
IUUC-Oar-089483	Ovis aries	75.95	0.00e+00	956.00
IUUC-Ptr-091387	Pan troglodytes	78.45	0.00e+00	960.00
IUUC-Pan-092623	Papio anubis	77.71	0.00e+00	937.00
IUUC-Psi-093830	Pelodiscus sinensis	84.09	0.00e+00	1112.00
IUUC-Pma-094135	Petromyzon marinus	41.28	6.00e-39	153.00
IUUC-Ppa-095379	Physcomitrella patens	54.42	2.00e-97	350.00
IUUC-Pfo-096755	Poecilia formosa	56.47	0.00e+00	810.00
IUUC-Pab-097564	Pongo abelii	75.25	0.00e+00	810.00
IUUC-Pop-099149	Populus trichocarpa	53.22	9.00e-104	370.00
IUUC-Pca-100357	Procavia capensis	85.78	4.00e-107	381.00
IUUC-Ppe-101237	Prunus persica	52.54	1.00e-101	364.00
IUUC-Pva-102397	Pteropus vampyrus	73.61	0.00e+00	918.00
IUUC-Rno-105349	Rattus norvegicus	77.26	0.00e+00	1017.00
IUUC-Smo-109409	Selaginella moellendorffii	53.38	5.00e-101	361.00
IUUC-Sit-110360	Setaria italica	52.54	2.00e-102	366.00
IUUC-Sly-111307	Solanum lycopersicum	52.54	2.00e-98	353.00
IUUC-Stu-112462	Solanum tuberosum	53.08	1.00e-97	349.00
IUUC-Sar-112953	Sorex araneus	71.49	4.00e-94	338.00
IUUC-Sbi-114389	Sorghum bicolor	46.10	1.00e-91	330.00
IUUC-Ssc-115949	Sus scrofa	75.77	0.00e+00	746.00
IUUC-Tgu-117461	Taeniopygia guttata	85.03	0.00e+00	1134.00
IUUC-Tru-117865	Takifugu rubripes	60.11	0.00e+00	808.00
IUUC-Tsy-119036	Tarsius syrichta	57.50	1.00e-60	226.00
IUUC-Tni-120903	Tetraodon nigroviridis	65.25	6.00e-151	527.00
IUUC-Tca-121185	Theobroma cacao	52.20	7.00e-101	362.00
IUUC-Tae-125307	Triticum aestivum	50.00	1.00e-100	360.00
IUUC-Tur-126181	Triticum urartu	46.62	4.00e-92	332.00
IUUC-Tbe-127518	Tupaia belangeri	63.66	2.00e-153	535.00
IUUC-Ttr-128172	Tursiops truncatus	76.69	0.00e+00	975.00
IUUC-Vvi-131489	Vitis vinifera	53.56	2.00e-103	370.00
IUUC-Xtr-132915	Xenopus tropicalis	69.30	0.00e+00	954.00
IUUC-Xma-134133	Xiphophorus maculatus	56.47	0.00e+00	804.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence