iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tni-120903

UUCD1 version

UUC-TeN-00458

Ensembl Protein ID

ENSTNIP00000005102.1

UniProt Accession

H3CA30; H3CA30_TETNG

Protein Name

Katanin p80 WD40 repeat-containing subunit B1; p80 katanin

Gene Name

katnb1; KATNB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000002551.1	ENSTNIT00000005248.1	ENSTNIP00000005102.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.10e-47	156.6	145	180
UBD/Beta-Prp	1.20e-60	205.4	12	257

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           gH+  v++laf +d + l+s+sdDgt+k+WDl +g+
   Q: 145  GHSQAVRSLAFsPDgKWLASASDDGTVKLWDLMQGK 180
           8***********999*****************9887 PP

UBD/Beta-Prp

   S: 44   llrslsgheaevtavkfspdgk.ilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee 131
            l++++ h+++v+++ + +++  +l+tg+ D  +++w +s+  c+++l gh++ v +++f+ s d +v+Gs+   irvwd+e  + ++ 
   Q: 12   RLQKFEAHSSTVSCLALGKSSGrLLATGGHDCRVNLWAVSKANCIMSLPGHKSPVECVQFNTSEDQIVTGSQSGSIRVWDMEAAKIVR- 99
           37899***********9665555*****************************************************************. PP
   S: 132  tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlng 220
           +l+gh+++++++++hp++  l+sGs D+ ++lWd ++   + + tg h ++v+sl+f+++gk l+s+s+dgtvklwdl +g+++ ++++
   Q: 100  MLTGHKSSISSLAFHPFQGFLASGSMDTNIKLWDFRRRGHVFRYTG-HSQAVRSLAFSPDGKWLASASDDGTVKLWDLMQGKTITEFTA 187
           *********************************************9.****************************************** PP
   S: 221  htdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvni 291
           ht+ v++v+f pn+ +l+sgssD+s+++Wdl++ +++++l++ ++ v+ + ++s+++  l++g+ d ++++
   Q: 188  HTAAVNVVQFNPNEYLLASGSSDRSVKLWDLEKFKMIGSLEGNATPVSRCICFSPDGDCLYSGATD-CLRV 257
           ***************************************************************998.5555 PP

Organism

Tetraodon nigroviridis

Functional Description
(View)

Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.

Protein Sequence
(Fasta)

MAAANTTKIS WRLQKFEAHS STVSCLALGK SSGRLLATGG HDCRVNLWAV SKANCIMSLP 60
GHKSPVECVQ FNTSEDQIVT GSQSGSIRVW DMEAAKIVRM LTGHKSSISS LAFHPFQGFL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCGCCG CAAACACCAC CAAGATTTCA TGGCGTCTGC GTGAGTCCGT TTCCTGCTGA 60
CACGTGCAAC TGTACACGAA TGCAGCGGTA ACCGTGTCCC CGCCTGTGTC ACCTGACAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-0498--Mitosis
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR026962--Katanin_bsu1
IPR028021--Katanin_C-terminal
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13925--Katanin_con80
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005813--C:centrosome
GO:0008352--C:katanin complex
GO:0005874--C:microtubule
GO:0000922--C:spindle pole
GO:0051301--P:cell division
GO:0051013--P:microtubule severing
GO:0030901--P:midbrain development
GO:0007067--P:mitotic nuclear division

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000954	Aegilops tauschii	44.85	8.00e-76	279.00
IUUC-Aml-002187	Ailuropoda melanoleuca	55.94	0.00e+00	709.00
IUUC-Atr-002899	Amborella trichopoda	49.49	5.00e-89	322.00
IUUC-Apl-003305	Anas platyrhynchos	59.13	0.00e+00	759.00
IUUC-Aca-004635	Anolis carolinensis	60.09	0.00e+00	729.00
IUUC-Aly-005711	Arabidopsis lyrata	49.34	9.00e-92	331.00
IUUC-Ath-007323	Arabidopsis thaliana	45.26	5.00e-92	332.00
IUUC-Ame-010870	Astyanax mexicanus	58.75	1.00e-101	362.00
IUUC-Bta-012527	Bos taurus	60.03	0.00e+00	758.00
IUUC-Bdi-014652	Brachypodium distachyon	47.85	2.00e-93	337.00
IUUC-Bol-016374	Brassica oleracea	48.34	8.00e-91	328.00
IUUC-Bra-017390	Brassica rapa	46.30	6.00e-91	328.00
IUUC-Cja-019706	Callithrix jacchus	61.00	0.00e+00	719.00
IUUC-Cfa-020139	Canis familiaris	50.35	8.00e-131	460.00
IUUC-Cpo-021710	Cavia porcellus	59.73	0.00e+00	740.00
IUUC-Cre-022746	Chlamydomonas reinhardtii	40.86	6.00e-67	248.00
IUUC-Csa-023546	Chlorocebus sabaeus	60.15	0.00e+00	694.00
IUUC-Cin-025156	Ciona intestinalis	37.37	1.00e-132	466.00
IUUC-Csv-025962	Ciona savignyi	42.71	2.00e-74	272.00
IUUC-Dre-028215	Danio rerio	61.64	0.00e+00	848.00
IUUC-Dno-029314	Dasypus novemcinctus	59.73	0.00e+00	729.00
IUUC-Dor-030482	Dipodomys ordii	60.96	0.00e+00	758.00
IUUC-Dme-032188	Drosophila melanogaster	36.20	9.00e-61	228.00
IUUC-Ete-032871	Echinops telfairi	32.58	6.00e-33	134.00
IUUC-Eca-034143	Equus caballus	60.90	0.00e+00	740.00
IUUC-Fca-035924	Felis catus	60.63	0.00e+00	748.00
IUUC-Fal-037387	Ficedula albicollis	60.57	0.00e+00	778.00
IUUC-Gmo-038692	Gadus morhua	66.03	3.00e-159	555.00
IUUC-Gga-040597	Gallus gallus	61.43	0.00e+00	796.00
IUUC-Gac-042004	Gasterosteus aculeatus	76.51	0.00e+00	1042.00
IUUC-Gma-044134	Glycine max	48.17	4.00e-90	325.00
IUUC-Ggo-044761	Gorilla gorilla	60.76	0.00e+00	715.00
IUUC-Hsa-045698	Homo sapiens	60.76	0.00e+00	731.00
IUUC-Hvu-047649	Hordeum vulgare	48.84	9.00e-92	331.00
IUUC-Itr-048697	Ictidomys tridecemlineatus	61.72	0.00e+00	732.00
IUUC-Lch-049674	Latimeria chalumnae	57.51	0.00e+00	787.00
IUUC-Lpe-051554	Leersia perrieri	49.83	4.00e-92	332.00
IUUC-Loc-052623	Lepisosteus oculatus	65.46	0.00e+00	873.00
IUUC-Laf-054587	Loxodonta africana	60.82	0.00e+00	769.00
IUUC-Mcc-055851	Macaca mulatta	60.76	0.00e+00	715.00
IUUC-Meu-056704	Macropus eugenii	61.77	0.00e+00	801.00
IUUC-Mtr-058053	Medicago truncatula	49.67	1.00e-93	337.00
IUUC-Mga-059608	Meleagris gallopavo	60.94	0.00e+00	786.00
IUUC-Mmr-061154	Microcebus murinus	61.67	0.00e+00	744.00
IUUC-Mdo-062365	Monodelphis domestica	59.49	0.00e+00	741.00
IUUC-Mmu-063754	Mus musculus	61.26	0.00e+00	739.00
IUUC-Mac-065100	Musa acuminata	49.15	6.00e-89	322.00
IUUC-Mpu-066245	Mustela putorius furo	59.88	0.00e+00	731.00
IUUC-Mlu-067692	Myotis lucifugus	60.63	0.00e+00	743.00
IUUC-Nle-070051	Nomascus leucogenys	61.31	0.00e+00	724.00
IUUC-Opr-070855	Ochotona princeps	60.15	0.00e+00	745.00
IUUC-Ont-071883	Oreochromis niloticus	71.21	0.00e+00	985.00
IUUC-Oan-073293	Ornithorhynchus anatinus	62.02	0.00e+00	700.00
IUUC-Ocu-074644	Oryctolagus cuniculus	61.63	0.00e+00	750.00
IUUC-Oba-075448	Oryza barthii	46.97	7.00e-92	332.00
IUUC-Obr-076385	Oryza brachyantha	49.50	2.00e-91	330.00
IUUC-Ogl-077427	Oryza glaberrima	49.83	7.00e-92	332.00
IUUC-Ogu-079022	Oryza glumaepatula	44.58	9.00e-84	305.00
IUUC-Oin-079811	Oryza indica	49.66	2.00e-89	323.00
IUUC-Olo-080245	Oryza longistaminata	49.66	3.00e-89	323.00
IUUC-Ome-081239	Oryza meridionalis	49.83	2.00e-89	323.00
IUUC-Oni-082640	Oryza nivara	46.97	7.00e-92	332.00
IUUC-Opu-083748	Oryza punctata	49.83	6.00e-92	332.00
IUUC-Oru-084609	Oryza rufipogon	46.97	7.00e-92	332.00
IUUC-Osa-085801	Oryza sativa	45.28	6.00e-85	308.00
IUUC-Ola-087483	Oryzias latipes	65.90	0.00e+00	758.00
IUUC-Oga-087964	Otolemur garnettii	61.18	0.00e+00	755.00
IUUC-Oar-089483	Ovis aries	59.79	0.00e+00	727.00
IUUC-Ptr-091387	Pan troglodytes	60.76	0.00e+00	731.00
IUUC-Pan-092623	Papio anubis	60.76	0.00e+00	715.00
IUUC-Psi-093830	Pelodiscus sinensis	60.90	0.00e+00	780.00
IUUC-Pma-094135	Petromyzon marinus	43.36	7.00e-37	146.00
IUUC-Ppa-095379	Physcomitrella patens	50.17	9.00e-86	311.00
IUUC-Pfo-096755	Poecilia formosa	70.66	0.00e+00	981.00
IUUC-Pab-097564	Pongo abelii	60.49	4.00e-180	624.00
IUUC-Pop-099149	Populus trichocarpa	50.00	1.00e-93	337.00
IUUC-Pca-100357	Procavia capensis	70.95	2.00e-87	316.00
IUUC-Ppe-101237	Prunus persica	50.33	3.00e-93	336.00
IUUC-Pva-102397	Pteropus vampyrus	58.83	0.00e+00	694.00
IUUC-Rno-105349	Rattus norvegicus	62.08	0.00e+00	763.00
IUUC-Sja-107934	Schizosaccharomyces japonicus	32.35	2.00e-32	134.00
IUUC-Smo-109379	Selaginella moellendorffii	49.66	7.00e-87	315.00
IUUC-Sit-110360	Setaria italica	46.63	2.00e-92	333.00
IUUC-Sly-111307	Solanum lycopersicum	49.67	2.00e-88	320.00
IUUC-Stu-112462	Solanum tuberosum	49.32	2.00e-85	309.00
IUUC-Sar-112953	Sorex araneus	54.15	2.00e-69	256.00
IUUC-Sbi-114389	Sorghum bicolor	43.65	3.00e-83	303.00
IUUC-Ssc-115949	Sus scrofa	57.50	1.00e-156	546.00
IUUC-Tgu-117461	Taeniopygia guttata	60.06	0.00e+00	788.00
IUUC-Tru-117865	Takifugu rubripes	83.81	0.00e+00	1179.00
IUUC-Tsy-119036	Tarsius syrichta	66.14	3.00e-45	175.00
IUUC-Tca-121185	Theobroma cacao	47.63	3.00e-91	330.00
IUUC-Tae-125307	Triticum aestivum	49.50	2.00e-92	333.00
IUUC-Tur-126181	Triticum urartu	44.55	2.00e-82	300.00
IUUC-Tbe-127518	Tupaia belangeri	49.01	1.00e-111	396.00
IUUC-Ttr-128172	Tursiops truncatus	61.20	0.00e+00	740.00
IUUC-Vvi-131489	Vitis vinifera	50.00	1.00e-93	337.00
IUUC-Xtr-132915	Xenopus tropicalis	59.25	0.00e+00	767.00
IUUC-Xma-134133	Xiphophorus maculatus	70.66	0.00e+00	971.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence