iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-090959

UUCD1 version

UUC-PaT-00443

Ensembl Protein ID

ENSPTRP00000022033.3

UniProt Accession

H2QJC9; H2QJC9_PANTR

Genbank Protein ID

JAA03576.1; JAA28469.1; JAA37033.1

Protein Name

BRCA1 associated RING domain 1

Genbank Nucleotide ID

AACZ03019594; GABD01004631; GABE01007706

Gene Name

BARD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000012888.3	ENSPTRT00000023895.3	ENSPTRP00000022033.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	33.80	4.00e-23	107.00	IUUC-Ath-006986
E3 activity/RING/RING	99.49	0.00e+00	1484.00	IUUC-Hsa-045826

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MPDNRQPRNR QPRIRSGNEP RSAPAMEPDG RGAWAHSRAA LDRLEKLLRC SRCTNILREP 60
VCLGGCEHIF CSNCVSDCIG TGCPVCYTPA WIQDLKINRQ LDSMIQLCSK LRNLLHDNEL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTCTGGCGG CCCGCCGTCC CAGACGCGGG AAGAGCTTGG CCGGTTTCGA GTCGCTGGCC 60
TGCAGCTTCC CGGTGGTTTC CCGAGGCCTC CTTGCTTCCC GCTCTCCGAG GAGCCTTTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0040--ANK repeat
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR033097--BARD1
IPR001357--BRCT_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS50172--BRCT
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF12796--Ank_2

PRINTS

PR01415--ANKYRIN

SMART

SM00248--ANK
SM00292--BRCT

Gene Ontology

GO:0070531--C:BRCA1-A complex
GO:0031436--C:BRCA1-BARD1 complex
GO:0016607--C:nuclear speck
GO:0000932--C:P-body
GO:0003723--F:RNA binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0043066--P:negative regulation of apoptotic process
GO:0046826--P:negative regulation of protein export from nucleus
GO:0043065--P:positive regulation of apoptotic process
GO:0085020--P:protein K6-linked ubiquitination
GO:0042325--P:regulation of phosphorylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000225	Aegilops tauschii	36.05	5.00e-20	93.20
IUUC-Aml-002346	Ailuropoda melanoleuca	82.95	0.00e+00	1145.00
IUUC-Atr-002625	Amborella trichopoda	34.71	1.00e-20	95.90
IUUC-Apl-004108	Anas platyrhynchos	51.52	0.00e+00	636.00
IUUC-Aca-005387	Anolis carolinensis	48.02	0.00e+00	680.00
IUUC-Ath-006986	Arabidopsis thaliana	37.50	2.00e-23	105.00
IUUC-Ame-011716	Astyanax mexicanus	54.55	3.00e-61	230.00
IUUC-Bta-013417	Bos taurus	83.05	0.00e+00	1175.00
IUUC-Bdi-014760	Brachypodium distachyon	32.88	4.00e-22	100.00
IUUC-Bol-016476	Brassica oleracea	37.75	1.00e-20	95.10
IUUC-Bra-017176	Brassica rapa	36.47	1.00e-23	105.00
IUUC-Cel-018312	Caenorhabditis elegans	26.30	2.00e-13	70.90
IUUC-Cja-019415	Callithrix jacchus	91.40	0.00e+00	1412.00
IUUC-Cfa-020351	Canis familiaris	82.08	0.00e+00	1051.00
IUUC-Cpo-021746	Cavia porcellus	74.45	0.00e+00	1085.00
IUUC-Csa-023450	Chlorocebus sabaeus	95.37	0.00e+00	1388.00
IUUC-Csv-025987	Ciona savignyi	37.43	5.00e-56	211.00
IUUC-Dno-029038	Dasypus novemcinctus	71.14	0.00e+00	990.00
IUUC-Dor-030826	Dipodomys ordii	74.55	0.00e+00	988.00
IUUC-Ete-033061	Echinops telfairi	71.81	0.00e+00	1017.00
IUUC-Eca-033710	Equus caballus	82.91	0.00e+00	859.00
IUUC-Eeu-035266	Erinaceus europaeus	66.45	0.00e+00	692.00
IUUC-Fca-035414	Felis catus	83.89	0.00e+00	1227.00
IUUC-Fal-037357	Ficedula albicollis	50.34	0.00e+00	685.00
IUUC-Gga-040255	Gallus gallus	53.63	0.00e+00	701.00
IUUC-Gma-044372	Glycine max	37.77	8.00e-21	96.70
IUUC-Ggo-045300	Gorilla gorilla	98.84	0.00e+00	1506.00
IUUC-Hsa-045826	Homo sapiens	99.49	0.00e+00	1484.00
IUUC-Itr-048456	Ictidomys tridecemlineatus	82.47	0.00e+00	1165.00
IUUC-Lch-050674	Latimeria chalumnae	48.09	1.00e-171	596.00
IUUC-Lpe-050895	Leersia perrieri	36.73	2.00e-20	95.10
IUUC-Laf-054591	Loxodonta africana	81.29	0.00e+00	1170.00
IUUC-Mcc-055017	Macaca mulatta	90.09	0.00e+00	1297.00
IUUC-Mtr-058400	Medicago truncatula	40.24	4.00e-25	110.00
IUUC-Mga-059484	Meleagris gallopavo	50.93	0.00e+00	655.00
IUUC-Mmr-061544	Microcebus murinus	83.91	0.00e+00	1264.00
IUUC-Mdo-062408	Monodelphis domestica	59.93	0.00e+00	832.00
IUUC-Mmu-064203	Mus musculus	70.25	0.00e+00	1021.00
IUUC-Mac-065131	Musa acuminata	28.96	2.00e-19	91.70
IUUC-Mpu-066899	Mustela putorius furo	81.81	0.00e+00	1142.00
IUUC-Mlu-067781	Myotis lucifugus	77.99	0.00e+00	1061.00
IUUC-Ncr-068884	Neurospora crassa	32.94	2.00e-06	48.10
IUUC-Nle-069031	Nomascus leucogenys	97.55	0.00e+00	1489.00
IUUC-Opr-070889	Ochotona princeps	72.78	0.00e+00	641.00
IUUC-Ont-072557	Oreochromis niloticus	51.10	2.00e-111	396.00
IUUC-Ocu-074785	Oryctolagus cuniculus	78.84	0.00e+00	1142.00
IUUC-Oba-075953	Oryza barthii	37.93	6.00e-20	92.40
IUUC-Obr-076308	Oryza brachyantha	38.78	2.00e-21	98.20
IUUC-Ogl-076938	Oryza glaberrima	37.93	6.00e-20	92.40
IUUC-Ogu-078659	Oryza glumaepatula	40.35	4.00e-16	80.50
IUUC-Oin-079086	Oryza indica	40.35	3.00e-16	80.50
IUUC-Olo-080264	Oryza longistaminata	40.35	3.00e-16	81.30
IUUC-Ome-081445	Oryza meridionalis	30.32	1.00e-16	82.40
IUUC-Oni-082364	Oryza nivara	37.93	6.00e-20	92.40
IUUC-Opu-083700	Oryza punctata	38.10	7.00e-21	96.30
IUUC-Oru-085093	Oryza rufipogon	40.35	3.00e-16	80.90
IUUC-Osa-085434	Oryza sativa	37.93	6.00e-20	92.40
IUUC-Olu-087823	Ostreococcus lucimarinus	37.10	4.00e-18	83.20
IUUC-Oga-088383	Otolemur garnettii	75.10	0.00e+00	995.00
IUUC-Oar-089357	Ovis aries	82.54	0.00e+00	1257.00
IUUC-Pan-092160	Papio anubis	94.85	0.00e+00	1402.00
IUUC-Psi-093036	Pelodiscus sinensis	52.70	3.00e-179	621.00
IUUC-Pab-098198	Pongo abelii	95.88	0.00e+00	1371.00
IUUC-Pop-099956	Populus trichocarpa	37.84	2.00e-22	101.00
IUUC-Ppe-101676	Prunus persica	45.45	1.00e-21	99.00
IUUC-Pva-102243	Pteropus vampyrus	84.61	0.00e+00	1239.00
IUUC-Rno-104832	Rattus norvegicus	68.78	0.00e+00	952.00
IUUC-Sha-107601	Sarcophilus harrisii	59.08	0.00e+00	791.00
IUUC-Sit-110609	Setaria italica	34.69	8.00e-19	89.40
IUUC-Sly-111863	Solanum lycopersicum	29.82	1.00e-20	95.10
IUUC-Stu-112154	Solanum tuberosum	30.74	9.00e-20	92.40
IUUC-Sar-113493	Sorex araneus	67.65	5.00e-73	268.00
IUUC-Sbi-114470	Sorghum bicolor	36.73	2.00e-20	94.40
IUUC-Ssc-115611	Sus scrofa	81.19	0.00e+00	1217.00
IUUC-Tgu-116812	Taeniopygia guttata	51.76	0.00e+00	725.00
IUUC-Tru-117996	Takifugu rubripes	37.23	2.00e-122	433.00
IUUC-Tsy-119446	Tarsius syrichta	68.23	0.00e+00	972.00
IUUC-Tni-120842	Tetraodon nigroviridis	39.01	2.00e-135	476.00
IUUC-Tca-121417	Theobroma cacao	38.51	2.00e-22	100.00
IUUC-Tae-124838	Triticum aestivum	30.17	9.00e-21	95.90
IUUC-Tur-126725	Triticum urartu	30.17	5.00e-21	96.70
IUUC-Tbe-127550	Tupaia belangeri	71.58	0.00e+00	992.00
IUUC-Ttr-128364	Tursiops truncatus	82.92	0.00e+00	1123.00
IUUC-Vpa-130659	Vicugna pacos	80.22	0.00e+00	996.00
IUUC-Vvi-131586	Vitis vinifera	31.17	1.00e-11	66.60
IUUC-Xtr-131846	Xenopus tropicalis	46.50	0.00e+00	630.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence