iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067028

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02027833

Gene Name

MUL1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000002796.2	ENSMLUT00000002791.2	ENSMLUP00000002541.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	92.90	0.00e+00	683.00	IUUC-Hsa-046597

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MENGGRPSLG QFILLGTSSV VTAVLYSVYR QKAQVAQELK GAKRIHLGED LKSILSEAPG 60
KCVPYAVIEG AVRSVKETLN SQFVENCKGV IQRLTLQEHK MVWNRTTHLW NDYSKIIHQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGAACG GAGGGCGGCC CTCGCTGGGC CAGTTCATCC TCCTGGGCAC CAGCTCCGTC 60
GTCACCGCCG TCCTGTACTC CGTGTACCGG CAGAAGGCCC AGGTCGCCCA AGAGCTCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR022170--GIDE
IPR001841--Znf_RING

PROSITE

PS50089--ZF_RING_2

Pfam

PF12483--GIDE

Gene Ontology

GO:0030424--C:axon
GO:0031307--C:integral component of mitochondrial outer membrane
GO:0043025--C:neuronal cell body
GO:0005777--C:peroxisome
GO:0004871--F:signal transducer activity
GO:0019789--F:SUMO transferase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007257--P:activation of JUN kinase activity
GO:0071360--P:cellular response to exogenous dsRNA
GO:0000266--P:mitochondrial fission
GO:0051646--P:mitochondrion localization
GO:0030308--P:negative regulation of cell growth
GO:0071650--P:negative regulation of chemokine (C-C motif) ligand 5 production
GO:0050689--P:negative regulation of defense response to virus by host
GO:0010637--P:negative regulation of mitochondrial fusion
GO:0051898--P:negative regulation of protein kinase B signaling
GO:0060339--P:negative regulation of type I interferon-mediated signaling pathway
GO:1903861--P:positive regulation of dendrite extension
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0090141--P:positive regulation of mitochondrial fission
GO:1904925--P:positive regulation of mitophagy in response to mitochondrial depolarization
GO:0033235--P:positive regulation of protein sumoylation
GO:0031648--P:protein destabilization
GO:0050821--P:protein stabilization
GO:0051881--P:regulation of mitochondrial membrane potential
GO:1901028--P:regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000342	Aegilops tauschii	25.82	2.00e-14	74.70
IUUC-Aml-002287	Ailuropoda melanoleuca	92.61	0.00e+00	655.00
IUUC-Atr-002698	Amborella trichopoda	23.74	2.00e-09	57.00
IUUC-Aca-005039	Anolis carolinensis	40.29	2.00e-66	245.00
IUUC-Aly-006181	Arabidopsis lyrata	28.41	3.00e-22	99.40
IUUC-Ath-007438	Arabidopsis thaliana	28.37	3.00e-23	102.00
IUUC-Ame-010671	Astyanax mexicanus	61.93	1.00e-130	459.00
IUUC-Bta-012407	Bos taurus	82.44	2.00e-168	584.00
IUUC-Bdi-014735	Brachypodium distachyon	26.45	1.00e-18	87.40
IUUC-Bol-015493	Brassica oleracea	26.93	1.00e-24	106.00
IUUC-Bra-016933	Brassica rapa	27.11	2.00e-21	96.70
IUUC-Cja-019709	Callithrix jacchus	92.21	1.00e-180	624.00
IUUC-Cfa-020818	Canis familiaris	94.32	0.00e+00	674.00
IUUC-Cpo-022490	Cavia porcellus	90.91	0.00e+00	634.00
IUUC-Csa-023259	Chlorocebus sabaeus	92.90	0.00e+00	683.00
IUUC-Cho-024730	Choloepus hoffmanni	92.05	0.00e+00	676.00
IUUC-Cin-025301	Ciona intestinalis	30.63	2.00e-47	183.00
IUUC-Dre-028644	Danio rerio	61.36	1.00e-130	459.00
IUUC-Dno-028925	Dasypus novemcinctus	90.34	0.00e+00	676.00
IUUC-Dor-030692	Dipodomys ordii	92.05	0.00e+00	650.00
IUUC-Dme-031761	Drosophila melanogaster	30.65	1.00e-33	137.00
IUUC-Ete-032329	Echinops telfairi	81.53	1.00e-156	545.00
IUUC-Eca-034008	Equus caballus	89.77	0.00e+00	666.00
IUUC-Eeu-034895	Erinaceus europaeus	75.64	1.00e-121	429.00
IUUC-Fca-036104	Felis catus	93.47	0.00e+00	666.00
IUUC-Fal-036900	Ficedula albicollis	71.72	2.00e-139	488.00
IUUC-Gmo-039049	Gadus morhua	57.95	1.00e-106	379.00
IUUC-Gga-040254	Gallus gallus	70.17	5.00e-145	507.00
IUUC-Gac-042277	Gasterosteus aculeatus	59.38	3.00e-134	471.00
IUUC-Gma-043979	Glycine max	26.89	9.00e-21	94.00
IUUC-Ggo-045509	Gorilla gorilla	92.90	0.00e+00	683.00
IUUC-Hsa-046597	Homo sapiens	92.90	0.00e+00	683.00
IUUC-Hvu-047335	Hordeum vulgare	26.64	2.00e-20	92.40
IUUC-Itr-048691	Ictidomys tridecemlineatus	92.05	0.00e+00	648.00
IUUC-Lch-050344	Latimeria chalumnae	66.76	4.00e-145	507.00
IUUC-Lpe-051343	Leersia perrieri	28.96	3.00e-15	75.90
IUUC-Loc-052376	Lepisosteus oculatus	66.48	2.00e-149	521.00
IUUC-Laf-054414	Loxodonta africana	92.90	0.00e+00	687.00
IUUC-Mcc-054604	Macaca mulatta	93.18	0.00e+00	685.00
IUUC-Meu-056087	Macropus eugenii	84.38	3.00e-172	597.00
IUUC-Mtr-057779	Medicago truncatula	26.76	2.00e-20	93.20
IUUC-Mga-060188	Meleagris gallopavo	71.79	5.00e-144	503.00
IUUC-Mmr-060704	Microcebus murinus	92.90	0.00e+00	686.00
IUUC-Mdo-062842	Monodelphis domestica	83.81	3.00e-165	573.00
IUUC-Mmu-064324	Mus musculus	90.06	0.00e+00	632.00
IUUC-Mac-064976	Musa acuminata	37.04	2.00e-07	51.20
IUUC-Mpu-065940	Mustela putorius furo	89.77	0.00e+00	627.00
IUUC-Nle-069254	Nomascus leucogenys	86.16	0.00e+00	628.00
IUUC-Opr-070827	Ochotona princeps	86.93	0.00e+00	652.00
IUUC-Ont-072008	Oreochromis niloticus	60.23	9.00e-137	479.00
IUUC-Oan-072935	Ornithorhynchus anatinus	80.40	4.00e-170	590.00
IUUC-Ocu-074526	Oryctolagus cuniculus	91.19	0.00e+00	637.00
IUUC-Oba-075954	Oryza barthii	28.96	3.00e-15	75.90
IUUC-Obr-076592	Oryza brachyantha	27.54	5.00e-24	105.00
IUUC-Ogl-077732	Oryza glaberrima	27.91	7.00e-24	104.00
IUUC-Ogu-078565	Oryza glumaepatula	28.96	2.00e-15	75.90
IUUC-Oin-080188	Oryza indica	27.91	7.00e-24	104.00
IUUC-Olo-080705	Oryza longistaminata	25.42	1.00e-13	71.60
IUUC-Ome-081154	Oryza meridionalis	28.85	3.00e-15	76.30
IUUC-Oni-082201	Oryza nivara	28.96	3.00e-15	75.90
IUUC-Opu-083497	Oryza punctata	28.96	2.00e-15	76.30
IUUC-Oru-084332	Oryza rufipogon	28.96	3.00e-15	75.90
IUUC-Osa-086059	Oryza sativa	28.85	1.00e-15	77.00
IUUC-Ola-087288	Oryzias latipes	57.95	2.00e-127	448.00
IUUC-Oga-088402	Otolemur garnettii	92.61	0.00e+00	682.00
IUUC-Oar-089851	Ovis aries	94.44	2.00e-89	321.00
IUUC-Ptr-091226	Pan troglodytes	92.61	0.00e+00	682.00
IUUC-Pan-092575	Papio anubis	92.90	0.00e+00	684.00
IUUC-Psi-094062	Pelodiscus sinensis	76.70	1.00e-165	575.00
IUUC-Pma-094501	Petromyzon marinus	37.54	1.00e-44	173.00
IUUC-Ppa-095285	Physcomitrella patens	24.53	7.00e-15	74.70
IUUC-Pfo-096146	Poecilia formosa	57.95	2.00e-123	434.00
IUUC-Pab-098524	Pongo abelii	92.61	0.00e+00	681.00
IUUC-Pop-099864	Populus trichocarpa	26.69	2.00e-19	90.10
IUUC-Pca-100314	Procavia capensis	91.48	0.00e+00	675.00
IUUC-Ppe-101663	Prunus persica	26.81	2.00e-19	90.10
IUUC-Pva-102947	Pteropus vampyrus	94.89	0.00e+00	696.00
IUUC-Rno-105024	Rattus norvegicus	90.91	0.00e+00	640.00
IUUC-Sha-107500	Sarcophilus harrisii	68.55	1.00e-123	436.00
IUUC-Smo-109194	Selaginella moellendorffii	27.35	1.00e-20	93.60
IUUC-Sit-109922	Setaria italica	25.95	3.00e-21	95.90
IUUC-Sly-111826	Solanum lycopersicum	27.33	2.00e-21	96.70
IUUC-Stu-112907	Solanum tuberosum	27.25	1.00e-20	94.00
IUUC-Sar-113522	Sorex araneus	89.42	3.00e-166	577.00
IUUC-Sbi-114536	Sorghum bicolor	27.62	4.00e-24	105.00
IUUC-Ssc-115445	Sus scrofa	93.47	0.00e+00	639.00
IUUC-Tgu-116551	Taeniopygia guttata	71.59	3.00e-136	478.00
IUUC-Tru-118407	Takifugu rubripes	57.10	9.00e-118	416.00
IUUC-Tsy-118794	Tarsius syrichta	89.49	0.00e+00	655.00
IUUC-Tni-120128	Tetraodon nigroviridis	63.14	1.00e-92	332.00
IUUC-Tca-121508	Theobroma cacao	27.09	3.00e-22	99.00
IUUC-Tae-125185	Triticum aestivum	26.98	8.00e-24	104.00
IUUC-Tur-126470	Triticum urartu	26.69	1.00e-23	103.00
IUUC-Tbe-127432	Tupaia belangeri	91.76	0.00e+00	633.00
IUUC-Ttr-128573	Tursiops truncatus	90.62	0.00e+00	649.00
IUUC-Vpa-130583	Vicugna pacos	92.31	1.00e-174	605.00
IUUC-Vvi-131710	Vitis vinifera	26.64	1.00e-18	87.40
IUUC-Xtr-132009	Xenopus tropicalis	61.86	2.00e-136	478.00
IUUC-Xma-134121	Xiphophorus maculatus	58.07	5.00e-128	450.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence