iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bol-015880

Ensembl Protein ID

Bo4g059750.1

UniProt Accession

A0A0D3BTM0; A0A0D3BTM0_BRAOL

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bo4g059750	Bo4g059750.1	Bo4g059750.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.80e-168	562.6	472	959

Active Site

Position(s)	Description	Evidence
653	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnvea 92
           YD Qi ++G++ q+kl+ akv+ vG g+lGcE+lKn++l+Gv     g++tv+D+d +e+snl+rqFLfr++++g+ K+ vaa a++ +np+ n+ea
   Q: 472  YDAQISVFGAKFQQKLEDAKVFTVGSGALGCEFLKNMALMGVscgdqGKLTVTDDDIIEKSNLSRQFLFRDWNIGQAKSTVAASAAAAINPKFNIEA 568
           ************************************************************************************************* PP
   S: 93   heesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaeht 186
            ++++ +++e+++   F ++++vVv+aldn+ ar++v+++cl+ ++pl+esgtlG + +++ +i++lte y +s+dpp+k++P+ct+ ++p +++h+
   Q: 569  LQNRVGAETENVFddaFWENLTVVVNALDNVNARLYVDSRCLYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAPMCTVHSFPHNIDHC 665
           ***********99************************************************************************************ PP
   S: 187  iewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikqllksfecdivtksksp 271
           ++wa            + +n +l+   + ++       ++ +++++++ + l +e+ enfe++ ++a+  f+ ++ n +kql+  f+ d  t+ ++p
   Q: 666  LTWArsefegllektpAEVNAYLSSPVEYTNSMMSAGDAQARDTLERIVECLDKEKCENFEDCLTWARLRFEDYFVNRVKQLIYTFPEDAATSTGAP 762
           *********999999977777777777777777777888999999999999999******************************************* PP
   S: 272  fwv.........................................................sfcsnaealqvpekvekdeevvkasap..lylllral 309
           fw+                                                          f++ ++a+ v +  +   ++ +++++  +  l+++l
   Q: 763  FWSapkrfprplqysssdpsllnfitatailraetfgipvpewtkdpkaaaeaidnvivpDFEPRKDAKIVTDEKATTLTTASVDDAavINDLVAKL 859
           *************************************************999999999998888887777666666666666666666877777777 PP
   S: 310  erfekk..kgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsg..kfeplknffl 400
           e+ +++  ++  ++ ++fekddd   ++d+++ +an+ra +++i++ +d+ + k iag+iipaiat +a+  Gl+++E++Kv++g  k e+++n+f 
   Q: 860  EKCRHNlsPDFRMKPIQFEKDDDTnyHMDVIAGLANMRARNYSIPE-VDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKVLDGghKVEAYRNTFA 955
           766654228899999*******************************.***************************************9*********9 PP
   S: 401  fdae 404
           ++a+
   Q: 956  NLAL 959
           9875 PP

Organism

Brassica oleracea

Protein Sequence
(Fasta)

MLHKRASEAS SVANEIVSSD LASPIKRRRI EITDSASENS SIVASGSSSS GGSVVQQRDM 60
AFGNSNRQEI DEDLHSRQLA VYGRETMRRL FASNVLISGM HGLGAEIAKN LILAGVKSVT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTTCACA AGCGAGCTAG TGAAGCGTCA TCTGTTGCTA ACGAGATCGT CAGTTCCGAT 60
TTAGCATCGC CGATTAAGAG ACGCCGCATC GAGATCACTG ATTCCGCGTC TGAGAACTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002684	Amborella trichopoda	77.80	0.00e+00	1651.00
IUUC-Aly-005418	Arabidopsis lyrata	92.15	0.00e+00	2035.00
IUUC-Ath-006992	Arabidopsis thaliana	92.51	0.00e+00	1999.00
IUUC-Bra-017252	Brassica rapa	98.58	0.00e+00	2112.00
IUUC-Ete-033124	Echinops telfairi	39.94	1.00e-128	454.00
IUUC-Gma-043165	Glycine max	84.49	0.00e+00	1824.00
IUUC-Mor-057269	Magnaporthe oryzae	45.57	0.00e+00	854.00
IUUC-Mtr-058572	Medicago truncatula	84.28	0.00e+00	1737.00
IUUC-Opr-070715	Ochotona princeps	35.17	3.00e-150	525.00
IUUC-Obr-076557	Oryza brachyantha	79.10	0.00e+00	1630.00
IUUC-Ogu-078305	Oryza glumaepatula	75.32	0.00e+00	1601.00
IUUC-Olo-081089	Oryza longistaminata	75.42	0.00e+00	1603.00
IUUC-Opu-083301	Oryza punctata	79.19	0.00e+00	1626.00
IUUC-Oru-084469	Oryza rufipogon	75.52	0.00e+00	1605.00
IUUC-Olu-087687	Ostreococcus lucimarinus	58.76	0.00e+00	1142.00
IUUC-Pma-094214	Petromyzon marinus	47.95	2.00e-36	144.00
IUUC-Ppa-095227	Physcomitrella patens	71.84	0.00e+00	1515.00
IUUC-Pop-098934	Populus trichocarpa	81.60	0.00e+00	1755.00
IUUC-Ppe-102012	Prunus persica	80.16	0.00e+00	1751.00
IUUC-Smo-109211	Selaginella moellendorffii	72.33	0.00e+00	1538.00
IUUC-Sly-110914	Solanum lycopersicum	79.35	0.00e+00	1730.00
IUUC-Stu-112001	Solanum tuberosum	78.01	0.00e+00	1683.00
IUUC-Tca-121436	Theobroma cacao	84.37	0.00e+00	1799.00
IUUC-Tae-125113	Triticum aestivum	78.32	0.00e+00	1590.00
IUUC-Vda-129977	Verticillium dahliae	48.06	0.00e+00	811.00
IUUC-Vvi-130857	Vitis vinifera	84.17	0.00e+00	1783.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence