iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037469

Ensembl Protein ID

ENSFALP00000011090.1

UniProt Accession

U3K7T6; U3K7T6_FICAL

Genbank Protein ID

ENSFALP00000011090

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01021662

Gene Name

WDR61

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000010627.1	ENSFALT00000011135.1	ENSFALP00000011090.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.20e-44	145.8	230	268
UBD/Beta-Prp	8.80e-76	254.6	12	303

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH ++v  +af +d t++vs+s D+++kvWD  t ++++
   Q: 230  GHGSWVLNVAFcPDdTHFVSSSSDKSVKVWDAGTRTCVH 268
           8***********777****************88877776 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkf....spdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvh 88
           +++h++ i +v++     ++++ +++gs d+ +kvw++ ++kl   ++l+gh+ +v +v++s++g i +++s D++i++wdl+tgk++ 
   Q: 12   EQAHDDAIWSVAWgknkNDGSETVISGSLDDLVKVWKWNDEKLdlQWTLEGHQLGVVSVDISHTGAIAASSSLDAHIRLWDLDTGKQIK 100
           5677788888999888677889********************9999******************************************* PP
   S: 89   tlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltg 177
           ++ +   +++sl+fsp++++l++Gsh+  ++++ +etg++ +  l+ + +++ +++++pdg++l+sG+ D++++++d++tgkll+tl+g
   Q: 101  SIDAGPVDAWSLAFSPDSQYLATGSHVGKVNIFGVETGKKEY-SLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEG 188
           ******************************************.*********************************************9 PP
   S: 178  ghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnss 266
            h  +++sl+f+++++ lv++s+dg++k++d+q+ +   tl gh ++v+ v+f+p+d+++vs ssD+s+++Wd  ++++++t+  h+++
   Q: 189  -HAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHGSWVLNVAFCPDDTHFVSSSSDKSVKVWDAGTRTCVHTFFDHQDQ 276
           .**************************************************************************************** PP
   S: 267  visvavlsfgdnvlvlgsedskvniwkl 294
           v+ v++ + +++++v++++d++++i+++
   Q: 277  VWGVKY-NGSGSKIVSVGDDQEIHIYDC 303
           ******.999****************97 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MTTQYGILFK QEQAHDDAIW SVAWGKNKND GSETVISGSL DDLVKVWKWN DEKLDLQWTL 60
EGHQLGVVSV DISHTGAIAA SSSLDAHIRL WDLDTGKQIK SIDAGPVDAW SLAFSPDSQY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACCACAC AGGTAATTAA AAACACAGCG TTAGCTAAGC TGACTGCTAG CTTGAGGTGT 60
GTATGTATAT ATATAGGCTG CTCATGTGTA ATATTAATTA TTTTTTCTTT TTAGTACGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016593--C:Cdc73/Paf1 complex
GO:0005829--C:cytosol
GO:0055087--C:Ski complex
GO:0035327--C:transcriptionally active chromatin
GO:0080182--P:histone H3-K4 trimethylation
GO:0045638--P:negative regulation of myeloid cell differentiation
GO:0051571--P:positive regulation of histone H3-K4 methylation
GO:2001162--P:positive regulation of histone H3-K79 methylation
GO:0032968--P:positive regulation of transcription elongation from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000774	Aegilops tauschii	34.13	5.00e-47	181.00
IUUC-Aml-002245	Ailuropoda melanoleuca	92.79	5.00e-159	553.00
IUUC-Atr-003142	Amborella trichopoda	50.93	1.00e-37	149.00
IUUC-Apl-003179	Anas platyrhynchos	96.39	2.00e-164	571.00
IUUC-Aca-004880	Anolis carolinensis	91.80	2.00e-162	563.00
IUUC-Aly-005956	Arabidopsis lyrata	38.98	8.00e-58	216.00
IUUC-Ath-007230	Arabidopsis thaliana	38.14	2.00e-52	198.00
IUUC-Acl-008297	Aspergillus clavatus	29.03	5.00e-25	108.00
IUUC-Ame-011511	Astyanax mexicanus	85.99	1.00e-152	531.00
IUUC-Bgr-012189	Blumeria graminis	31.90	3.00e-30	125.00
IUUC-Bta-012936	Bos taurus	93.11	3.00e-159	553.00
IUUC-Bdi-015020	Brachypodium distachyon	38.19	9.00e-47	180.00
IUUC-Bol-015927	Brassica oleracea	38.78	2.00e-58	218.00
IUUC-Bra-017323	Brassica rapa	38.98	4.00e-58	218.00
IUUC-Cja-019961	Callithrix jacchus	93.11	2.00e-159	554.00
IUUC-Cfa-020862	Canis familiaris	93.11	5.00e-159	552.00
IUUC-Cpo-021356	Cavia porcellus	92.72	4.00e-157	546.00
IUUC-Cre-022602	Chlamydomonas reinhardtii	41.91	3.00e-58	218.00
IUUC-Csa-024067	Chlorocebus sabaeus	92.79	5.00e-159	553.00
IUUC-Cho-024421	Choloepus hoffmanni	80.30	1.00e-80	291.00
IUUC-Cin-025261	Ciona intestinalis	64.26	3.00e-117	414.00
IUUC-Cgl-026446	Colletotrichum gloeosporioides	28.62	3.00e-29	122.00
IUUC-Cne-026846	Cryptococcus neoformans	28.25	4.00e-23	101.00
IUUC-Dre-027706	Danio rerio	66.56	4.00e-113	400.00
IUUC-Dno-029084	Dasypus novemcinctus	92.18	2.00e-157	547.00
IUUC-Dor-030353	Dipodomys ordii	78.62	2.00e-116	411.00
IUUC-Dse-031348	Dothistroma septosporum	31.22	3.00e-26	112.00
IUUC-Dme-031836	Drosophila melanogaster	51.08	2.00e-87	315.00
IUUC-Ete-032261	Echinops telfairi	90.16	3.00e-153	533.00
IUUC-Eca-034231	Equus caballus	84.92	3.00e-143	500.00
IUUC-Eeu-034828	Erinaceus europaeus	91.75	8.00e-148	515.00
IUUC-Fca-036569	Felis catus	93.11	1.00e-158	551.00
IUUC-Fox-038047	Fusarium oxysporum	34.12	6.00e-30	124.00
IUUC-Gmo-039579	Gadus morhua	84.92	8.00e-149	519.00
IUUC-Gga-040808	Gallus gallus	98.63	2.00e-160	557.00
IUUC-Gac-042100	Gasterosteus aculeatus	87.87	4.00e-153	533.00
IUUC-Gma-044408	Glycine max	40.94	4.00e-61	228.00
IUUC-Ggo-045227	Gorilla gorilla	93.11	2.00e-159	554.00
IUUC-Hsa-045839	Homo sapiens	93.11	2.00e-159	554.00
IUUC-Hvu-047591	Hordeum vulgare	38.06	3.00e-49	188.00
IUUC-Itr-048741	Ictidomys tridecemlineatus	92.79	4.00e-159	553.00
IUUC-Lch-049549	Latimeria chalumnae	84.26	3.00e-148	516.00
IUUC-Lpe-050746	Leersia perrieri	38.91	7.00e-48	184.00
IUUC-Loc-052540	Lepisosteus oculatus	88.20	5.00e-152	529.00
IUUC-Lma-052992	Leptosphaeria maculans	29.25	1.00e-27	116.00
IUUC-Laf-053907	Loxodonta africana	92.79	4.00e-159	553.00
IUUC-Mcc-055828	Macaca mulatta	87.08	3.00e-155	540.00
IUUC-Meu-056075	Macropus eugenii	95.29	2.00e-135	474.00
IUUC-Mor-056971	Magnaporthe oryzae	31.39	3.00e-24	105.00
IUUC-Mtr-057728	Medicago truncatula	41.35	6.00e-59	220.00
IUUC-Mga-059872	Meleagris gallopavo	98.69	6.00e-169	585.00
IUUC-Mvi-060564	Microbotryum violaceum	31.88	3.00e-31	128.00
IUUC-Mmr-060985	Microcebus murinus	93.49	4.00e-152	530.00
IUUC-Mdo-062758	Monodelphis domestica	90.79	1.00e-158	551.00
IUUC-Mmu-063580	Mus musculus	90.49	3.00e-156	543.00
IUUC-Mac-064880	Musa acuminata	40.84	3.00e-59	221.00
IUUC-Mpu-066577	Mustela putorius furo	92.46	5.00e-158	549.00
IUUC-Nle-069573	Nomascus leucogenys	93.11	2.00e-159	554.00
IUUC-Opr-070216	Ochotona princeps	92.36	2.00e-156	544.00
IUUC-Ont-071981	Oreochromis niloticus	87.21	9.00e-154	535.00
IUUC-Oan-073223	Ornithorhynchus anatinus	95.96	1.00e-109	387.00
IUUC-Ocu-074199	Oryctolagus cuniculus	79.34	1.00e-130	458.00
IUUC-Oba-075255	Oryza barthii	40.77	1.00e-41	162.00
IUUC-Obr-076168	Oryza brachyantha	46.58	6.00e-35	140.00
IUUC-Ogl-077777	Oryza glaberrima	38.71	1.00e-48	186.00
IUUC-Ogu-078780	Oryza glumaepatula	38.71	1.00e-48	186.00
IUUC-Oin-079228	Oryza indica	38.71	2.00e-51	195.00
IUUC-Olo-080617	Oryza longistaminata	45.07	1.00e-28	118.00
IUUC-Ome-081421	Oryza meridionalis	38.71	8.00e-48	183.00
IUUC-Oni-082997	Oryza nivara	38.71	2.00e-51	195.00
IUUC-Opu-083931	Oryza punctata	39.03	1.00e-48	186.00
IUUC-Oru-084645	Oryza rufipogon	38.71	1.00e-48	186.00
IUUC-Osa-085842	Oryza sativa	38.71	2.00e-51	195.00
IUUC-Ola-086696	Oryzias latipes	87.54	4.00e-150	523.00
IUUC-Olu-087643	Ostreococcus lucimarinus	39.91	4.00e-41	160.00
IUUC-Oga-088272	Otolemur garnettii	92.43	7.00e-157	545.00
IUUC-Oar-089416	Ovis aries	93.11	3.00e-159	553.00
IUUC-Ptr-090944	Pan troglodytes	93.11	2.00e-159	554.00
IUUC-Pan-091861	Papio anubis	93.11	2.00e-159	554.00
IUUC-Psi-093750	Pelodiscus sinensis	97.05	5.00e-166	576.00
IUUC-Pma-094608	Petromyzon marinus	81.61	4.00e-138	483.00
IUUC-Pno-094832	Phaeosphaeria nodorum	37.36	2.00e-26	112.00
IUUC-Ppa-095737	Physcomitrella patens	40.06	1.00e-57	216.00
IUUC-Pfo-096479	Poecilia formosa	88.52	9.00e-147	512.00
IUUC-Pab-098179	Pongo abelii	93.11	2.00e-159	554.00
IUUC-Pop-099532	Populus trichocarpa	41.26	2.00e-57	215.00
IUUC-Pca-100664	Procavia capensis	72.46	3.00e-100	357.00
IUUC-Ppe-102056	Prunus persica	39.94	2.00e-58	218.00
IUUC-Pva-102859	Pteropus vampyrus	92.79	4.00e-158	550.00
IUUC-Pte-104236	Pyrenophora teres	36.81	9.00e-26	110.00
IUUC-Rno-105826	Rattus norvegicus	90.16	1.00e-155	541.00
IUUC-Sha-106660	Sarcophilus harrisii	92.69	1.00e-151	528.00
IUUC-Sja-107800	Schizosaccharomyces japonicus	33.55	4.00e-36	144.00
IUUC-Spo-108244	Schizosaccharomyces pombe	31.25	2.00e-34	139.00
IUUC-Smo-109234	Selaginella moellendorffii	43.14	2.00e-62	232.00
IUUC-Sit-110048	Setaria italica	37.46	2.00e-40	159.00
IUUC-Sly-111618	Solanum lycopersicum	39.10	3.00e-53	201.00
IUUC-Stu-112543	Solanum tuberosum	38.78	6.00e-56	210.00
IUUC-Sar-113743	Sorex araneus	73.11	4.00e-122	430.00
IUUC-Sbi-114309	Sorghum bicolor	39.52	5.00e-42	164.00
IUUC-Ssc-115560	Sus scrofa	87.87	2.00e-147	514.00
IUUC-Tgu-117300	Taeniopygia guttata	99.67	2.00e-170	590.00
IUUC-Tru-117933	Takifugu rubripes	87.54	2.00e-153	534.00
IUUC-Tsy-119574	Tarsius syrichta	81.97	7.00e-135	472.00
IUUC-Tni-120191	Tetraodon nigroviridis	89.03	5.00e-115	406.00
IUUC-Tca-120983	Theobroma cacao	41.10	1.00e-59	223.00
IUUC-Tae-124056	Triticum aestivum	37.10	3.00e-49	188.00
IUUC-Tur-126711	Triticum urartu	36.98	7.00e-48	183.00
IUUC-Tme-127066	Tuber melanosporum	33.83	1.00e-34	140.00
IUUC-Tbe-127802	Tupaia belangeri	93.11	1.00e-158	551.00
IUUC-Ttr-128861	Tursiops truncatus	89.68	3.00e-52	197.00
IUUC-Vda-129720	Verticillium dahliae	29.27	2.00e-23	102.00
IUUC-Vpa-130618	Vicugna pacos	89.07	7.00e-127	445.00
IUUC-Vvi-130981	Vitis vinifera	41.03	1.00e-57	216.00
IUUC-Xtr-132460	Xenopus tropicalis	88.52	4.00e-151	526.00
IUUC-Xma-134154	Xiphophorus maculatus	88.52	8.00e-147	512.00
IUUC-Yli-134554	Yarrowia lipolytica	29.89	1.00e-22	100.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence