iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ppa-095390

Ensembl Protein ID

PP1S11_79V6.1

UniProt Accession

A9RIE1; A9RIE1_PHYPA

Genbank Protein ID

EDQ81177.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

DS544900

Gene Name

PHYPADRAFT_175161

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PP1S11_79V6	PP1S11_79V6.1	PP1S11_79V6.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.00e-37	124.8	91	127
UBD/Beta-Prp	8.60e-76	255.7	3	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH d ++ ++f ++ + +vs+sdD ti++W++ + ++
   Q: 91   GHLDYIRTVQFhHEnPWIVSASDDQTIRIWNWQSRTC 127
           8**********95569***************987766 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvls 99
           t +++++++++ + f+p +++++++  +g i++wd+++g+l+ ++ +h+++v+ v f+++++++v+g++D+ ikvw+++ + c+ tl gh d++++
   Q: 3    TKFETKSNRVKGLSFHPRRPWILASLHSGIIQLWDYRMGTLIDRFDEHDGPVRGVHFHKSQPLFVSGGDDYKIKVWNYKMRRCLFTLLGHLDYIRT 98
           67889999**************************************************************************************** PP
   S: 100  lsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl..........................ktg 169
           ++f+ ++ ++vs+s+d+tir+w++++++c++ +l+gh++ v+c+++h +++l+vs+slD+tvr+Wd+                            +
   Q: 99   VQFHHENPWIVSASDDQTIRIWNWQSRTCIS-VLTGHNHYVMCASFHIKEDLVVSASLDQTVRVWDIgalrkksvapavdmlrltqmntdlfgGGD 193
           *******************************.**************************************************77777777776444 PP
   S: 170  kllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlh 263
           ++++   +gh++ v++ sf+++ + +vsg++d++vklw +  ++   v+tl+gh +nv++v f+ +++++vs s+D+sir+Wd+ +++ ++t+ ++
   Q: 194  SVVKYVLEGHDRGVNWASFHPSLPLIVSGADDRQVKLWRMNDTKAweVDTLRGHVNNVSCVMFHARQDIIVSNSEDKSIRVWDMSKRTGVQTFRRE 289
           444444555********************************777668************************************************* PP
   S: 264  nssvisvavlsfgdnvlvlgsedskvniwklkknep 299
           +++++  ++ +++ n l++g  ds   ++kl++++p
   Q: 290  QDRFWILSA-HPEMNLLAAG-HDSGMIVFKLERERP 323
           *********.6666655555.689999999988765 PP

Organism

Physcomitrella patens

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MLTKFETKSN RVKGLSFHPR RPWILASLHS GIIQLWDYRM GTLIDRFDEH DGPVRGVHFH 60
KSQPLFVSGG DDYKIKVWNY KMRRCLFTLL GHLDYIRTVQ FHHENPWIVS ASDDQTIRIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTGACTA AGTTCGAGAC GAAGAGTAAT AGGGTGAAGG GGCTCAGCTT TCACCCGCGG 60
CGGCCATGGA TCCTGGCCAG TTTGCACAGC GGTATCATTC AGCTGTGGGA CTACCGAATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011048--Haem_d1
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

KEGG

ppp:PHYPADRAFT_175161

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000064	Aegilops tauschii	68.49	0.00e+00	1718.00
IUUC-Aca-005154	Anolis carolinensis	78.71	3.00e-95	340.00
IUUC-Acl-008027	Aspergillus clavatus	49.51	0.00e+00	1175.00
IUUC-Dre-027421	Danio rerio	57.21	0.00e+00	1412.00
IUUC-Lpe-051316	Leersia perrieri	70.07	0.00e+00	1738.00
IUUC-Lma-053138	Leptosphaeria maculans	49.52	0.00e+00	1170.00
IUUC-Oba-075761	Oryza barthii	68.82	0.00e+00	1731.00
IUUC-Ogl-077364	Oryza glaberrima	69.01	0.00e+00	1740.00
IUUC-Ogu-078257	Oryza glumaepatula	68.76	0.00e+00	1687.00
IUUC-Oin-079274	Oryza indica	68.93	0.00e+00	1741.00
IUUC-Oni-082874	Oryza nivara	69.01	0.00e+00	1740.00
IUUC-Opu-083885	Oryza punctata	69.66	0.00e+00	1742.00
IUUC-Oru-084274	Oryza rufipogon	68.93	0.00e+00	1738.00
IUUC-Osa-085565	Oryza sativa	68.93	0.00e+00	1738.00
IUUC-Sce-106464	Saccharomyces cerevisiae	43.56	0.00e+00	972.00
IUUC-Tae-123611	Triticum aestivum	68.58	0.00e+00	1721.00
IUUC-Tur-126754	Triticum urartu	67.70	0.00e+00	1697.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence