iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tca-121545

Ensembl Protein ID

EOX97900

UniProt Accession

A0A061DYV6; A0A061DYV6_THECC

Genbank Protein ID

EOX97900.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

CM001880

Gene Name

TCM_006813

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TCM_006813	EOX97900	EOX97900

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.70e-38	128.2	91	127
UBD/Beta-Prp	2.20e-76	257.9	3	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH d ++ ++f ++ + +vs+sdD ti++W++ + ++
   Q: 91   GHLDYIRTVQFhHEhPWIVSASDDQTIRIWNWQSRTC 127
           8**********97779***************987766 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp 104
           t +++++++++ + f+ ++++++++  +g i++wd+++g+l+ ++ +h+++v+ v f+ +++++v+g++D+ ikvw+++   c+ tl gh d++++++f+ 
   Q: 3    TKFETKSNRVKGLSFHAKRPWILASLHSGVIQLWDYRMGTLIDRFDEHDGPVRGVHFHMSQPLFVSGGDDYKIKVWNYKLHRCLFTLLGHLDYIRTVQFHH 103
           67889999********************************************************************************************* PP
   S: 105  sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl..........................ktgkllrtltggh 179
           +  ++vs+s+d+tir+w++++++c++ +l+gh++ v+c+++hp+++l+vs+slD+tvr+Wd+                            +++++   +gh
   Q: 104  EHPWIVSASDDQTIRIWNWQSRTCIS-VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIgslrkktvspaddilrlsqmntdlfgGVDSVVKYVLEGH 203
           **************************.**************************************************88877777777555555555666* PP
   S: 180  tdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdn 278
           ++ v++ +f+++ + +vsg++d++vklw + +++   v+tl+gh +nv++v f+ +++++vs s+D+sir+Wd+++++ l+t+ +++++++  a+ +++ n
   Q: 204  DRGVNWAAFHPTLPLIVSGADDRQVKLWRMNETKAweVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKSIRVWDVTKRTGLQTFRREHDRFWILAA-HPEMN 303
           *******************************887778**********************************************************.66666 PP
   S: 279  vlvlgsedskvniwklkknep 299
            l++g  ds   ++kl++++p
   Q: 304  LLAAG-HDSGMIVFKLERERP 323
           55555.689999999988765 PP

Organism

Theobroma cacao

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MLTKFETKSN RVKGLSFHAK RPWILASLHS GVIQLWDYRM GTLIDRFDEH DGPVRGVHFH 60
MSQPLFVSGG DDYKIKVWNY KLHRCLFTLL GHLDYIRTVQ FHHEHPWIVS ASDDQTIRIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTTTCGTTT GTAATTTTAG ATGCTACATC AGATCTGAGG TAATTTTTTC TTAGTTTCAT 60
GCCCATAACT TCGATCTTCC TTATCTCTAT GCTTGGTTCC CAAATCCAAA TCTCCCTGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011048--Haem_d1
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000201	Aegilops tauschii	78.52	0.00e+00	1947.00
IUUC-Atr-002493	Amborella trichopoda	83.76	0.00e+00	2052.00
IUUC-Aca-005154	Anolis carolinensis	78.43	4.00e-95	339.00
IUUC-Afu-008964	Aspergillus fumigatus	48.30	0.00e+00	1129.00
IUUC-Ani-009379	Aspergillus nidulans	55.73	0.00e+00	988.00
IUUC-Bci-013781	Botrytis cinerea	55.89	0.00e+00	972.00
IUUC-Bdi-014549	Brachypodium distachyon	78.21	0.00e+00	2015.00
IUUC-Cel-018115	Caenorhabditis elegans	55.49	0.00e+00	949.00
IUUC-Csv-025864	Ciona savignyi	59.36	0.00e+00	1004.00
IUUC-Dme-031945	Drosophila melanogaster	61.86	0.00e+00	1049.00
IUUC-Ete-032873	Echinops telfairi	60.88	0.00e+00	1056.00
IUUC-Fox-037738	Fusarium oxysporum	48.10	0.00e+00	1135.00
IUUC-Ggr-039931	Gaeumannomyces graminis	55.89	0.00e+00	970.00
IUUC-Gma-043257	Glycine max	86.43	0.00e+00	2144.00
IUUC-Hvu-047556	Hordeum vulgare	78.95	0.00e+00	2021.00
IUUC-Lpe-051553	Leersia perrieri	78.41	0.00e+00	1926.00
IUUC-Loc-051867	Lepisosteus oculatus	51.05	0.00e+00	827.00
IUUC-Lma-053138	Leptosphaeria maculans	55.60	0.00e+00	983.00
IUUC-Meu-056238	Macropus eugenii	57.61	0.00e+00	785.00
IUUC-Mtr-058248	Medicago truncatula	85.25	0.00e+00	2146.00
IUUC-Mvi-060336	Microbotryum violaceum	60.19	0.00e+00	1073.00
IUUC-Mac-065272	Musa acuminata	73.20	0.00e+00	1818.00
IUUC-Nfi-068270	Neosartorya fischeri	56.21	0.00e+00	979.00
IUUC-Nle-069634	Nomascus leucogenys	66.92	0.00e+00	953.00
IUUC-Oba-074992	Oryza barthii	77.71	0.00e+00	1880.00
IUUC-Obr-076153	Oryza brachyantha	76.03	0.00e+00	1735.00
IUUC-Ogl-077364	Oryza glaberrima	79.51	0.00e+00	2009.00
IUUC-Ogu-078257	Oryza glumaepatula	79.19	0.00e+00	1943.00
IUUC-Oin-079274	Oryza indica	79.34	0.00e+00	2004.00
IUUC-Oni-082874	Oryza nivara	79.43	0.00e+00	2004.00
IUUC-Opu-083885	Oryza punctata	79.51	0.00e+00	2009.00
IUUC-Oru-084274	Oryza rufipogon	79.43	0.00e+00	2006.00
IUUC-Osa-085565	Oryza sativa	79.43	0.00e+00	2006.00
IUUC-Olu-087639	Ostreococcus lucimarinus	62.64	0.00e+00	1567.00
IUUC-Psi-093044	Pelodiscus sinensis	55.61	0.00e+00	904.00
IUUC-Pfo-097493	Poecilia formosa	54.78	0.00e+00	1347.00
IUUC-Pop-099992	Populus trichocarpa	89.50	0.00e+00	2177.00
IUUC-Ptt-103978	Puccinia triticina	52.22	0.00e+00	819.00
IUUC-Pte-104126	Pyrenophora teres	55.15	0.00e+00	936.00
IUUC-Sit-109697	Setaria italica	79.77	0.00e+00	2013.00
IUUC-Sly-111759	Solanum lycopersicum	84.25	0.00e+00	2143.00
IUUC-Sbi-114388	Sorghum bicolor	78.52	0.00e+00	2008.00
IUUC-Tae-123688	Triticum aestivum	78.77	0.00e+00	2020.00
IUUC-Tur-126016	Triticum urartu	77.74	0.00e+00	1867.00
IUUC-Tbe-127882	Tupaia belangeri	69.03	2.00e-128	452.00
IUUC-Vda-129828	Verticillium dahliae	47.57	0.00e+00	1110.00
IUUC-Xma-133138	Xiphophorus maculatus	54.78	0.00e+00	1347.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence