iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nfi-068424

Ensembl Protein ID

CADNFIAP00006442

UniProt Accession

A1DE24; ATG18_NEOFI

Genbank Protein ID

EAW17631.1

Protein Name

Autophagy-related protein 18

Genbank Nucleotide ID

DS027696

Gene Name

NFIA_075610; atg18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADNFIAG00006609	CADNFIAT00006609	CADNFIAP00006442

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-07	31.1	186	223

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgt.ikvWDlrtgvll 36
           H ++  c+ + sd tll+++sd gt i+v+++ +g++l
   Q: 186  HRSPLACITLnSDgTLLATASDKGTiIRVFSVPDGHKL 223
           999********999***********999****999876 PP

Organism

Neosartorya fischeri

Functional Description
(View)

The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Necessary for proper vacuole morphology. Plays an important role in osmotically-induced vacuole fragmentation. Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy. Involved in correct atg9 trafficking to the pre-autophagosomal structure. Might also be involved in premeiotic DNA replication (By similarity).

Protein Sequence
(Fasta)

MAMNFVTFNQ DYSYLAVATS KGFRIFTTDP FAKSYETKEG NIAIIEMLFS TSLVALILSP 60
RRLQITNTKR QSTICELTFP TTVLAVKLNR KRLVIVLEDQ IYLYDIQTMK LLYTIQTSPN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAATGA ACTTCGTGAC CTTCAACCAA GACTACAGCT ATCTGGCTGT TGGTAAGCGC 60
CCCTTGGAAC TCTTCAGGCG CATGCGCACG CTCTAAGGCT CTGTATTCCC TCCATCAGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0072--Autophagy
KW-0181--Complete proteome
KW-0967--Endosome
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0926--Vacuole
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

SMART

SM00320--WD40

Gene Ontology

GO:0010008--C:endosome membrane
GO:0000329--C:fungal-type vacuole membrane
GO:0005794--C:Golgi apparatus
GO:0034045--C:pre-autophagosomal structure membrane
GO:0016236--P:macroautophagy
GO:0015031--P:protein transport

KEGG

nfi:NFIA_075610

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000966	Aegilops tauschii	31.38	5.00e-48	183.00
IUUC-Aml-001842	Ailuropoda melanoleuca	44.71	3.00e-56	211.00
IUUC-Atr-002710	Amborella trichopoda	32.24	1.00e-43	169.00
IUUC-Apl-003390	Anas platyrhynchos	44.31	3.00e-57	214.00
IUUC-Aca-004975	Anolis carolinensis	44.53	2.00e-60	225.00
IUUC-Ago-007948	Ashbya gossypii	42.15	1.00e-70	259.00
IUUC-Acl-008148	Aspergillus clavatus	90.41	0.00e+00	721.00
IUUC-Afl-008562	Aspergillus flavus	85.75	0.00e+00	663.00
IUUC-Afu-008936	Aspergillus fumigatus	97.25	0.00e+00	783.00
IUUC-Ani-009254	Aspergillus nidulans	86.95	0.00e+00	721.00
IUUC-Ang-009798	Aspergillus niger	86.99	0.00e+00	669.00
IUUC-Aor-010066	Aspergillus oryzae	85.75	0.00e+00	663.00
IUUC-Ate-010266	Aspergillus terreus	89.86	0.00e+00	698.00
IUUC-Ame-010727	Astyanax mexicanus	45.28	3.00e-61	227.00
IUUC-Bta-012655	Bos taurus	44.53	2.00e-60	224.00
IUUC-Bci-013627	Botrytis cinerea	63.06	3.00e-135	473.00
IUUC-Bdi-014739	Brachypodium distachyon	30.68	1.00e-47	182.00
IUUC-Cel-018503	Caenorhabditis elegans	30.57	5.00e-48	183.00
IUUC-Cja-018829	Callithrix jacchus	44.27	9.00e-55	206.00
IUUC-Cfa-020858	Canis familiaris	41.46	9.00e-57	212.00
IUUC-Cpo-022235	Cavia porcellus	44.11	2.00e-59	221.00
IUUC-Cre-022613	Chlamydomonas reinhardtii	34.07	2.00e-40	158.00
IUUC-Csa-023963	Chlorocebus sabaeus	43.48	6.00e-56	209.00
IUUC-Cho-024328	Choloepus hoffmanni	46.46	8.00e-55	206.00
IUUC-Cin-025343	Ciona intestinalis	42.96	6.00e-53	199.00
IUUC-Csv-025920	Ciona savignyi	36.02	2.00e-65	240.00
IUUC-Cgl-026425	Colletotrichum gloeosporioides	70.59	2.00e-55	207.00
IUUC-Cne-026947	Cryptococcus neoformans	51.06	3.00e-101	360.00
IUUC-Dre-027490	Danio rerio	45.11	3.00e-61	227.00
IUUC-Dno-030057	Dasypus novemcinctus	44.71	2.00e-57	214.00
IUUC-Dor-030472	Dipodomys ordii	44.12	3.00e-54	204.00
IUUC-Dse-031215	Dothistroma septosporum	50.58	3.00e-119	419.00
IUUC-Ete-032362	Echinops telfairi	40.94	8.00e-50	189.00
IUUC-Eca-034362	Equus caballus	44.31	2.00e-57	214.00
IUUC-Fca-036230	Felis catus	44.49	5.00e-57	213.00
IUUC-Fal-036782	Ficedula albicollis	43.63	5.00e-57	213.00
IUUC-Fox-037797	Fusarium oxysporum	71.04	5.00e-98	349.00
IUUC-Fso-038174	Fusarium solani	70.27	8.00e-97	345.00
IUUC-Gmo-039706	Gadus morhua	33.09	1.00e-55	208.00
IUUC-Ggr-040113	Gaeumannomyces graminis	71.15	4.00e-104	369.00
IUUC-Gga-040690	Gallus gallus	44.53	1.00e-60	225.00
IUUC-Gac-041360	Gasterosteus aculeatus	44.91	5.00e-61	226.00
IUUC-Gma-043876	Glycine max	44.15	2.00e-56	211.00
IUUC-Hsa-046782	Homo sapiens	43.87	3.00e-56	210.00
IUUC-Itr-048693	Ictidomys tridecemlineatus	43.87	2.00e-56	211.00
IUUC-Kpa-049378	Komagataella pastoris	48.40	1.00e-74	272.00
IUUC-Lch-050413	Latimeria chalumnae	39.86	2.00e-54	204.00
IUUC-Lpe-051205	Leersia perrieri	31.67	7.00e-48	182.00
IUUC-Lma-052948	Leptosphaeria maculans	62.74	1.00e-151	527.00
IUUC-Laf-054007	Loxodonta africana	44.15	2.00e-60	224.00
IUUC-Meu-056020	Macropus eugenii	30.45	1.00e-30	125.00
IUUC-Mor-057125	Magnaporthe oryzae	55.75	3.00e-136	476.00
IUUC-Mtr-058536	Medicago truncatula	31.43	1.00e-46	178.00
IUUC-Mga-059795	Meleagris gallopavo	44.31	3.00e-57	213.00
IUUC-Mvi-060219	Microbotryum violaceum	49.65	3.00e-102	363.00
IUUC-Mmr-061096	Microcebus murinus	42.05	6.00e-58	216.00
IUUC-Mdo-062881	Monodelphis domestica	44.15	6.00e-60	222.00
IUUC-Mmu-063787	Mus musculus	44.53	1.00e-60	225.00
IUUC-Mac-064838	Musa acuminata	30.98	4.00e-48	183.00
IUUC-Mpu-066019	Mustela putorius furo	42.86	2.00e-57	214.00
IUUC-Mlu-068016	Myotis lucifugus	44.53	1.00e-60	225.00
IUUC-Ncr-068833	Neurospora crassa	57.08	3.00e-132	463.00
IUUC-Opr-070933	Ochotona princeps	47.06	3.00e-39	154.00
IUUC-Ont-072495	Oreochromis niloticus	45.66	2.00e-61	228.00
IUUC-Oan-073084	Ornithorhynchus anatinus	46.02	2.00e-54	204.00
IUUC-Ocu-074689	Oryctolagus cuniculus	44.49	5.00e-60	223.00
IUUC-Oba-075827	Oryza barthii	31.67	6.00e-48	182.00
IUUC-Ogl-077630	Oryza glaberrima	31.67	6.00e-48	182.00
IUUC-Ogu-078089	Oryza glumaepatula	39.47	6.00e-40	156.00
IUUC-Oin-079071	Oryza indica	39.47	8.00e-40	155.00
IUUC-Oni-083063	Oryza nivara	39.47	6.00e-40	156.00
IUUC-Oru-084845	Oryza rufipogon	39.47	7.00e-40	155.00
IUUC-Osa-086113	Oryza sativa	39.47	6.00e-40	156.00
IUUC-Oga-088894	Otolemur garnettii	43.87	2.00e-56	211.00
IUUC-Oar-089850	Ovis aries	43.92	3.00e-57	213.00
IUUC-Ptr-090456	Pan troglodytes	43.87	2.00e-56	211.00
IUUC-Pan-092111	Papio anubis	44.11	1.00e-59	222.00
IUUC-Psi-094095	Pelodiscus sinensis	44.31	2.00e-57	214.00
IUUC-Pno-095015	Phaeosphaeria nodorum	62.62	1.00e-141	494.00
IUUC-Ppa-095480	Physcomitrella patens	30.98	3.00e-43	167.00
IUUC-Pfo-096987	Poecilia formosa	45.28	3.00e-61	227.00
IUUC-Pab-097754	Pongo abelii	43.87	4.00e-56	210.00
IUUC-Ppe-101799	Prunus persica	31.63	2.00e-41	161.00
IUUC-Pva-103047	Pteropus vampyrus	41.70	3.00e-57	214.00
IUUC-Pte-104139	Pyrenophora teres	61.56	9.00e-141	491.00
IUUC-Pyt-104488	Pyrenophora triticirepentis	60.52	6.00e-141	492.00
IUUC-Rno-105990	Rattus norvegicus	44.53	1.00e-60	225.00
IUUC-Sce-106327	Saccharomyces cerevisiae	35.86	4.00e-79	286.00
IUUC-Sha-106581	Sarcophilus harrisii	43.53	2.00e-56	211.00
IUUC-Sja-107913	Schizosaccharomyces japonicus	38.70	2.00e-76	277.00
IUUC-Spo-108068	Schizosaccharomyces pombe	52.19	8.00e-69	252.00
IUUC-Ssl-108418	Sclerotinia sclerotiorum	62.35	1.00e-143	501.00
IUUC-Smo-109446	Selaginella moellendorffii	33.02	8.00e-51	192.00
IUUC-Sly-111030	Solanum lycopersicum	29.59	9.00e-46	176.00
IUUC-Sre-115219	Sporisorium reilianum	50.11	2.00e-104	370.00
IUUC-Ssc-116360	Sus scrofa	44.53	3.00e-60	223.00
IUUC-Tgu-116951	Taeniopygia guttata	44.31	3.00e-57	214.00
IUUC-Tru-117889	Takifugu rubripes	42.50	5.00e-58	216.00
IUUC-Tsy-119533	Tarsius syrichta	32.50	9.00e-18	81.60
IUUC-Tre-121895	Trichoderma reesei	57.67	3.00e-135	473.00
IUUC-Tvi-122311	Trichoderma virens	57.08	1.00e-137	481.00
IUUC-Tae-124901	Triticum aestivum	31.38	6.00e-48	182.00
IUUC-Uma-129438	Ustilago maydis	49.89	3.00e-95	340.00
IUUC-Vda-129782	Verticillium dahliae	53.78	7.00e-92	328.00
IUUC-Vvi-131674	Vitis vinifera	31.04	7.00e-48	182.00
IUUC-Xma-133370	Xiphophorus maculatus	45.28	3.00e-61	227.00
IUUC-Yli-134337	Yarrowia lipolytica	48.96	6.00e-99	352.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence