iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-096267

Ensembl Protein ID

ENSPFOP00000013939.2

UniProt Accession

A0A087Y7D6; A0A087Y7D6_POEFO

Genbank Protein ID

ENSPFOP00000013939

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AYCK01015502

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000013439.2	ENSPFOT00000013958.2	ENSPFOP00000013939.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.60e-98	330.1	1679	2058

Active Site

Position(s)	Description	Evidence
2025	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 6    kkrlevefvgEegldlgGvtreflallskelqnpdlglf........lysendketlqpnpdsglknp................... 65
           ++ le+++++E g++l G+t+ef+al+s+elq++dlgl+                  + n++     +                   
   Q: 1679 RAMLEIQYENEVGTGL-GPTQEFYALVSQELQRADLGLWrgeeitlaN--------PKGNQEGT---Kymfnsrglfavpfgrttkp 1753
           56899***********.**********************555444331........22222211...12233356666679999999 PP
   S: 66   ....ehlklFeflGrllgkalqdgrlldlplsksfyklllgk..klsledleevdpelykslkeikenaes................ 130
               +    F+flG+l++ka++d rlldlpl  +fyk +l++  ++s +dl ++dp ++ks++ +++   +                
   Q: 1754 ahiaKIKMKFRFLGKLMAKAIMDFRLLDLPLGLPFYKWMLRHetSISSHDLMNIDPSVAKSIQHLEDIIRQkkrleqdrsqtretlq 1840
           ***999999*********************************334666******************998334455556666677775 PP
   S: 131  ...........dieelgldltfsvseei.....lgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfnevi 201
                      ++e+            +     l+   + eLk gG+++pVt+ N+eeY +lvv ++l+eg+ +q+++freGf++v+
   Q: 1841 qaleslnmngcSVED------------LgldftLPGFPNIELKKGGKDVPVTIYNLEEYLRLVVYWTLNEGVSRQFDSFREGFESVF 1915
           444444444444444............34455578999************************************************* PP
   S: 202  plellslFteeelellicGe..eeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprl 286
           pl++l++F +eel++l+cG+  e++dv++l + ++ ++gyt+ds+ai++++evl++f++e+++ fLqFvTgs+rlP+gGf++l+p l
   Q: 1916 PLHHLQYFYPEELDQLLCGSksETWDVKTLMECCRPDHGYTHDSRAIRFLFEVLSSFDAEQQRLFLQFVTGSPRLPVGGFRSLNPPL 2002
           *******************98889*************************************************************** PP
   S: 287  fvirk.....dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFels 336
           +++rk     ++ dd lPs++TC+nyLkLP+Yss ei++ekLl+A +e+ ++F+ls
   Q: 2003 TIVRKtfestENPDDFLPSVMTCVNYLKLPDYSSIEIMREKLLIAAREGqQSFHLS 2058
           ********988888***************************************985 PP

Organism

Poecilia formosa

Protein Sequence
(Fasta)

MSNRPNSNPG GSLRRSQRNT AAAQPQDHTA AGRLQSEQVK HKPNSPPESR RPNSKAPKAT 60
ASSATGQSRG HSSRRSGLNL SVASLVLQDD SQAAGTSEQE RPGHQSKSEG TRGLKRSDAP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAAGCTGATG TCGAAAATCA CGGTTATCTA GTTCCACAGC GGATGAATAA CGCGGATGTA 60
TATTGCAGTT GTAGGCCGCT CAGCTGATAC GAAGCTAGCA GGGGTAGAGA GAGAAAAGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000569--HECT_dom
IPR004170--WWE-dom
IPR018123--WWE-dom_subgr

PROSITE

PS50237--HECT
PS50918--WWE

Pfam

PF00632--HECT
PF02825--WWE

SMART

SM00119--HECTc
SM00678--WWE

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000750	Aegilops tauschii	38.52	3.00e-128	454.00
IUUC-Aml-001502	Ailuropoda melanoleuca	81.99	0.00e+00	3065.00
IUUC-Atr-002821	Amborella trichopoda	37.45	1.00e-118	422.00
IUUC-Apl-003531	Anas platyrhynchos	80.38	0.00e+00	2966.00
IUUC-Aly-005962	Arabidopsis lyrata	38.74	4.00e-117	417.00
IUUC-Ath-006636	Arabidopsis thaliana	38.74	2.00e-117	418.00
IUUC-Ago-007875	Ashbya gossypii	36.65	3.00e-83	304.00
IUUC-Acl-008242	Aspergillus clavatus	37.03	1.00e-119	425.00
IUUC-Afl-008736	Aspergillus flavus	40.00	3.00e-116	414.00
IUUC-Afu-008812	Aspergillus fumigatus	37.37	2.00e-120	427.00
IUUC-Ani-009407	Aspergillus nidulans	37.15	8.00e-114	406.00
IUUC-Ang-009763	Aspergillus niger	40.15	4.00e-109	390.00
IUUC-Aor-009941	Aspergillus oryzae	31.64	7.00e-120	426.00
IUUC-Ate-010459	Aspergillus terreus	34.23	2.00e-90	328.00
IUUC-Ame-011761	Astyanax mexicanus	92.50	0.00e+00	3142.00
IUUC-Bgr-012265	Blumeria graminis	36.31	2.00e-106	381.00
IUUC-Bta-013070	Bos taurus	80.25	0.00e+00	3017.00
IUUC-Bci-013890	Botrytis cinerea	40.12	1.00e-104	375.00
IUUC-Bdi-014046	Brachypodium distachyon	37.90	1.00e-122	435.00
IUUC-Bol-015942	Brassica oleracea	43.65	3.00e-115	410.00
IUUC-Bra-016849	Brassica rapa	43.65	1.00e-114	409.00
IUUC-Cja-019046	Callithrix jacchus	86.69	0.00e+00	2969.00
IUUC-Cfa-020521	Canis familiaris	80.59	0.00e+00	2966.00
IUUC-Cpo-021639	Cavia porcellus	78.93	0.00e+00	2979.00
IUUC-Cre-022767	Chlamydomonas reinhardtii	39.50	1.00e-89	323.00
IUUC-Csa-023231	Chlorocebus sabaeus	88.28	0.00e+00	3042.00
IUUC-Cho-024380	Choloepus hoffmanni	80.65	0.00e+00	1911.00
IUUC-Cin-025482	Ciona intestinalis	50.28	2.00e-158	551.00
IUUC-Csv-026121	Ciona savignyi	47.92	0.00e+00	1538.00
IUUC-Cgl-026716	Colletotrichum gloeosporioides	35.04	1.00e-109	392.00
IUUC-Cne-026857	Cryptococcus neoformans	40.42	3.00e-95	344.00
IUUC-Cme-027226	Cyanidioschyzon merolae	35.32	5.00e-75	277.00
IUUC-Dre-028174	Danio rerio	93.28	0.00e+00	3199.00
IUUC-Dor-030939	Dipodomys ordii	83.67	0.00e+00	1265.00
IUUC-Dse-031444	Dothistroma septosporum	39.92	2.00e-109	391.00
IUUC-Dme-032162	Drosophila melanogaster	58.50	0.00e+00	717.00
IUUC-Ete-032345	Echinops telfairi	79.65	0.00e+00	2053.00
IUUC-Eca-033229	Equus caballus	81.80	0.00e+00	3021.00
IUUC-Eeu-035205	Erinaceus europaeus	71.37	0.00e+00	2557.00
IUUC-Fca-036444	Felis catus	80.41	0.00e+00	3042.00
IUUC-Fal-037131	Ficedula albicollis	83.00	0.00e+00	3142.00
IUUC-Fox-038035	Fusarium oxysporum	35.76	5.00e-109	388.00
IUUC-Fso-038320	Fusarium solani	36.17	9.00e-110	392.00
IUUC-Gmo-039497	Gadus morhua	88.25	0.00e+00	3304.00
IUUC-Ggr-040057	Gaeumannomyces graminis	35.05	3.00e-106	381.00
IUUC-Gga-041021	Gallus gallus	83.54	0.00e+00	3151.00
IUUC-Gac-042474	Gasterosteus aculeatus	90.40	0.00e+00	3388.00
IUUC-Gma-043060	Glycine max	38.68	1.00e-121	432.00
IUUC-Ggo-044855	Gorilla gorilla	86.64	0.00e+00	2967.00
IUUC-Hsa-046147	Homo sapiens	85.41	0.00e+00	2967.00
IUUC-Hvu-047775	Hordeum vulgare	38.66	2.00e-126	447.00
IUUC-Itr-048131	Ictidomys tridecemlineatus	88.02	0.00e+00	3026.00
IUUC-Kpa-049098	Komagataella pastoris	36.90	5.00e-84	306.00
IUUC-Lch-049818	Latimeria chalumnae	86.80	0.00e+00	2932.00
IUUC-Lpe-051017	Leersia perrieri	37.71	4.00e-119	423.00
IUUC-Loc-051777	Lepisosteus oculatus	87.94	0.00e+00	3330.00
IUUC-Lma-052990	Leptosphaeria maculans	36.93	5.00e-116	413.00
IUUC-Laf-053727	Loxodonta africana	81.61	0.00e+00	3042.00
IUUC-Mcc-055799	Macaca mulatta	88.58	0.00e+00	2965.00
IUUC-Meu-056065	Macropus eugenii	82.69	0.00e+00	1903.00
IUUC-Mor-057054	Magnaporthe oryzae	39.13	3.00e-104	374.00
IUUC-Mpo-057417	Magnaporthe poae	39.39	1.00e-106	382.00
IUUC-Mtr-057849	Medicago truncatula	36.78	4.00e-114	407.00
IUUC-Mla-058870	Melampsora laricipopulina	41.70	6.00e-109	389.00
IUUC-Mga-059580	Meleagris gallopavo	81.40	0.00e+00	2631.00
IUUC-Mvi-060507	Microbotryum violaceum	39.45	1.00e-114	409.00
IUUC-Mmr-060816	Microcebus murinus	83.16	0.00e+00	3129.00
IUUC-Mdo-062866	Monodelphis domestica	80.82	0.00e+00	2910.00
IUUC-Mmu-063906	Mus musculus	81.90	0.00e+00	3078.00
IUUC-Mac-064675	Musa acuminata	38.03	2.00e-111	397.00
IUUC-Mpu-066199	Mustela putorius furo	81.75	0.00e+00	3021.00
IUUC-Mlu-067110	Myotis lucifugus	81.85	0.00e+00	3043.00
IUUC-Nfi-068482	Neosartorya fischeri	37.12	2.00e-119	424.00
IUUC-Ncr-068906	Neurospora crassa	38.68	8.00e-107	383.00
IUUC-Nle-069410	Nomascus leucogenys	86.51	0.00e+00	2957.00
IUUC-Opr-070401	Ochotona princeps	75.08	0.00e+00	1724.00
IUUC-Ont-072100	Oreochromis niloticus	95.09	0.00e+00	3544.00
IUUC-Oan-073121	Ornithorhynchus anatinus	83.11	0.00e+00	3185.00
IUUC-Ocu-074623	Oryctolagus cuniculus	80.64	0.00e+00	3003.00
IUUC-Oba-075380	Oryza barthii	31.32	1.00e-114	408.00
IUUC-Obr-076915	Oryza brachyantha	36.97	1.00e-119	425.00
IUUC-Ogl-077055	Oryza glaberrima	38.18	9.00e-120	426.00
IUUC-Ogu-078892	Oryza glumaepatula	30.99	4.00e-114	406.00
IUUC-Oin-079256	Oryza indica	37.85	9.00e-119	422.00
IUUC-Olo-080343	Oryza longistaminata	37.85	1.00e-118	422.00
IUUC-Ome-081422	Oryza meridionalis	37.85	2.00e-118	421.00
IUUC-Oni-083047	Oryza nivara	31.32	2.00e-115	411.00
IUUC-Opu-083641	Oryza punctata	39.49	3.00e-108	387.00
IUUC-Oru-084439	Oryza rufipogon	31.21	2.00e-114	407.00
IUUC-Osa-085972	Oryza sativa	37.75	4.00e-118	419.00
IUUC-Ola-087173	Oryzias latipes	91.37	0.00e+00	3439.00
IUUC-Olu-087871	Ostreococcus lucimarinus	37.07	7.00e-88	318.00
IUUC-Oga-087908	Otolemur garnettii	81.38	0.00e+00	3070.00
IUUC-Oar-090277	Ovis aries	81.27	0.00e+00	3083.00
IUUC-Ptr-091543	Pan troglodytes	85.46	0.00e+00	2969.00
IUUC-Pan-092243	Papio anubis	88.52	0.00e+00	2963.00
IUUC-Psi-093150	Pelodiscus sinensis	82.45	0.00e+00	3134.00
IUUC-Pno-094891	Phaeosphaeria nodorum	42.26	6.00e-115	410.00
IUUC-Ppa-095181	Physcomitrella patens	42.14	7.00e-107	381.00
IUUC-Pab-098072	Pongo abelii	86.79	0.00e+00	2966.00
IUUC-Pop-099190	Populus trichocarpa	37.71	1.00e-116	415.00
IUUC-Pca-100311	Procavia capensis	76.10	0.00e+00	2735.00
IUUC-Ppe-101284	Prunus persica	37.57	7.00e-116	413.00
IUUC-Pva-102215	Pteropus vampyrus	81.01	0.00e+00	1034.00
IUUC-Pgr-103694	Puccinia graminis	40.12	6.00e-107	383.00
IUUC-Ptt-103916	Puccinia triticina	39.53	5.00e-103	370.00
IUUC-Pte-104346	Pyrenophora teres	41.87	2.00e-113	404.00
IUUC-Pyt-104508	Pyrenophora triticirepentis	41.87	6.00e-113	403.00
IUUC-Rno-105315	Rattus norvegicus	88.35	0.00e+00	2942.00
IUUC-Sce-106273	Saccharomyces cerevisiae	35.04	4.00e-70	260.00
IUUC-Sha-106835	Sarcophilus harrisii	81.99	0.00e+00	3187.00
IUUC-Sja-107943	Schizosaccharomyces japonicus	39.52	8.00e-98	352.00
IUUC-Spo-108081	Schizosaccharomyces pombe	39.76	8.00e-97	349.00
IUUC-Ssl-108560	Sclerotinia sclerotiorum	40.12	9.00e-109	389.00
IUUC-Smo-109590	Selaginella moellendorffii	42.91	3.00e-112	400.00
IUUC-Sit-109757	Setaria italica	37.77	3.00e-123	437.00
IUUC-Sly-111469	Solanum lycopersicum	38.99	5.00e-122	433.00
IUUC-Stu-112896	Solanum tuberosum	37.23	8.00e-106	378.00
IUUC-Sar-113224	Sorex araneus	68.28	0.00e+00	1480.00
IUUC-Sbi-114313	Sorghum bicolor	38.14	6.00e-125	442.00
IUUC-Sre-114993	Sporisorium reilianum	33.00	1.00e-100	362.00
IUUC-Ssc-115535	Sus scrofa	78.45	0.00e+00	2949.00
IUUC-Tgu-117493	Taeniopygia guttata	80.64	0.00e+00	2378.00
IUUC-Tru-118669	Takifugu rubripes	90.06	0.00e+00	3325.00
IUUC-Tsy-119373	Tarsius syrichta	81.41	0.00e+00	1645.00
IUUC-Tni-120049	Tetraodon nigroviridis	83.30	0.00e+00	922.00
IUUC-Tca-121779	Theobroma cacao	38.40	3.00e-115	410.00
IUUC-Tre-122195	Trichoderma reesei	35.81	1.00e-105	379.00
IUUC-Tvi-122650	Trichoderma virens	35.79	2.00e-107	385.00
IUUC-Tae-123580	Triticum aestivum	38.58	4.00e-126	446.00
IUUC-Tur-126295	Triticum urartu	38.52	1.00e-127	452.00
IUUC-Tme-126964	Tuber melanosporum	40.67	4.00e-108	387.00
IUUC-Tbe-128149	Tupaia belangeri	74.70	0.00e+00	1134.00
IUUC-Ttr-128165	Tursiops truncatus	84.30	0.00e+00	2751.00
IUUC-Uma-129365	Ustilago maydis	34.99	2.00e-87	318.00
IUUC-Vda-129725	Verticillium dahliae	41.12	3.00e-108	387.00
IUUC-Vpa-130678	Vicugna pacos	84.92	0.00e+00	2402.00
IUUC-Vvi-131147	Vitis vinifera	38.69	3.00e-121	430.00
IUUC-Xtr-132636	Xenopus tropicalis	79.93	0.00e+00	2969.00
IUUC-Xma-133458	Xiphophorus maculatus	99.61	0.00e+00	3689.00
IUUC-Yli-134481	Yarrowia lipolytica	38.89	1.00e-98	355.00
IUUC-Zma-135782	Zea mays	37.70	2.00e-118	421.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence