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Tag Content
iUUCD ID IUUC-Ago-007827
Ensembl Protein ID AAS51425
UniProt Accession Q75BS2; SEC13_ASHGO
Genbank Protein ID AAS51425.1
Protein Name Protein transport protein SEC13
Genbank Nucleotide ID AE016816
Gene Name SEC13; ACR199C
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AGOS_ACR199C AAS51425 AAS51425
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.60e-26 89.3 51 83
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf..sd..tllvsGsdDgtikvWD 29
           gH+++v+ +++  +    +l+s+s+Dg++ +W 
   Q: 51   GHEGPVWQVDWahPKfgVILASCSYDGKVLIWK 83
           8***********95554779************8 PP
   
Organism Ashbya gossypii
Functional Description
(View)

Functional Description


     Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. SEC13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity).
 Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. SEC13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity).
Protein Sequence
(Fasta)
MVTITNAHTE LIHDAVLDYY GKRLATCSSD KTIQIFEVDG DSHKLVDSLH GHEGPVWQVD 60
WAHPKFGVIL ASCSYDGKVL IWKEENGRWS QIAAYEVHSA SVNSVKWAPH EYGPLLLCSS 120
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Protein Fasta Sequence


>IUUC-Ago-007827|E3,WD_repeat|Ashbya gossypii
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Nucleotide Sequence
(Fasta)
ATGGTGACGA TTACGAATGC ACATACCGAG CTAATCCACG ATGCGGTTCT CGATTACTAC 60
GGAAAGCGCC TGGCAACATG TTCTTCGGAC AAGACAATCC AGATCTTCGA AGTCGATGGG 120
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Nucleotide Fasta Sequence


>IUUC-Ago-007827|E3,WD_repeat|Ashbya gossypii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0968--Cytoplasmic vesicle
KW-0256--Endoplasmic reticulum
KW-0931--ER-Golgi transport
KW-0472--Membrane
KW-0509--mRNA transport
KW-0906--Nuclear pore complex
KW-0539--Nucleus
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0811--Translocation
KW-0813--Transport
KW-0853--WD repeat
Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0030127--C:COPII vesicle coat
GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0031080--C:nuclear pore outer ring
GO:0035859--C:Seh1-associated complex
GO:0005198--F:structural molecule activity
GO:0090114--P:COPII-coated vesicle budding
GO:0051028--P:mRNA transport
GO:0031081--P:nuclear pore distribution
GO:0043547--P:positive regulation of GTPase activity
GO:1904263--P:positive regulation of TORC1 signaling
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0015031--P:protein transport
GO:0030433--P:ubiquitin-dependent ERAD pathway
KEGG ago:AGOS_ACR199C
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000671 Aegilops tauschii 45.85 7.00e-75 271.00
IUUC-Aml-001832 Ailuropoda melanoleuca 50.33 2.00e-84 303.00
IUUC-Atr-002914 Amborella trichopoda 47.33 9.00e-75 271.00
IUUC-Apl-003992 Anas platyrhynchos 52.05 3.00e-82 296.00
IUUC-Aca-005283 Anolis carolinensis 49.67 6.00e-83 298.00
IUUC-Aly-005654 Arabidopsis lyrata 46.49 1.00e-69 254.00
IUUC-Ath-006810 Arabidopsis thaliana 47.16 4.00e-71 258.00
IUUC-Acl-008205 Aspergillus clavatus 56.77 3.00e-95 339.00
IUUC-Afl-008748 Aspergillus flavus 55.52 9.00e-95 337.00
IUUC-Afu-008791 Aspergillus fumigatus 57.10 3.00e-95 339.00
IUUC-Ani-009152 Aspergillus nidulans 56.73 3.00e-99 352.00
IUUC-Ang-009765 Aspergillus niger 56.73 2.00e-97 346.00
IUUC-Aor-009927 Aspergillus oryzae 55.96 3.00e-93 332.00
IUUC-Ate-010248 Aspergillus terreus 56.09 8.00e-97 344.00
IUUC-Ame-011478 Astyanax mexicanus 49.67 5.00e-83 298.00
IUUC-Bgr-012276 Blumeria graminis 51.16 1.00e-88 317.00
IUUC-Bta-012700 Bos taurus 50.00 5.00e-83 298.00
IUUC-Bci-013722 Botrytis cinerea 52.15 4.00e-91 325.00
IUUC-Bdi-014818 Brachypodium distachyon 46.18 1.00e-74 271.00
IUUC-Bol-015779 Brassica oleracea 46.82 2.00e-69 253.00
IUUC-Bra-016973 Brassica rapa 46.13 8.00e-70 256.00
IUUC-Cel-018479 Caenorhabditis elegans 39.66 8.00e-59 218.00
IUUC-Cja-019956 Callithrix jacchus 50.18 7.00e-77 278.00
IUUC-Cfa-020752 Canis familiaris 50.00 1.00e-83 300.00
IUUC-Cpo-021871 Cavia porcellus 50.00 8.00e-84 301.00
IUUC-Cre-022797 Chlamydomonas reinhardtii 45.30 3.00e-74 269.00
IUUC-Csa-023393 Chlorocebus sabaeus 50.00 2.00e-83 300.00
IUUC-Cho-024786 Choloepus hoffmanni 43.18 2.00e-29 120.00
IUUC-Cin-025332 Ciona intestinalis 48.51 2.00e-80 290.00
IUUC-Csv-025926 Ciona savignyi 49.50 3.00e-80 289.00
IUUC-Cgl-026413 Colletotrichum gloeosporioides 53.24 2.00e-88 316.00
IUUC-Cne-027054 Cryptococcus neoformans 44.72 5.00e-75 271.00
IUUC-Cme-027165 Cyanidioschyzon merolae 33.71 2.00e-44 172.00
IUUC-Dre-027782 Danio rerio 50.00 1.00e-82 297.00
IUUC-Dno-029628 Dasypus novemcinctus 49.34 1.00e-82 298.00
IUUC-Dor-030650 Dipodomys ordii 48.92 1.00e-62 230.00
IUUC-Dse-031206 Dothistroma septosporum 50.65 1.00e-86 310.00
IUUC-Dme-031854 Drosophila melanogaster 50.00 1.00e-75 274.00
IUUC-Ete-032618 Echinops telfairi 33.77 2.00e-41 160.00
IUUC-Eca-033268 Equus caballus 50.33 1.00e-83 300.00
IUUC-Fca-035918 Felis catus 49.67 5.00e-83 298.00
IUUC-Fal-037551 Ficedula albicollis 51.02 2.00e-78 283.00
IUUC-Fox-037763 Fusarium oxysporum 52.96 6.00e-89 318.00
IUUC-Fso-038341 Fusarium solani 51.78 3.00e-87 312.00
IUUC-Gmo-038638 Gadus morhua 50.66 2.00e-84 303.00
IUUC-Ggr-039865 Gaeumannomyces graminis 52.65 2.00e-88 317.00
IUUC-Gga-040193 Gallus gallus 51.32 5.00e-85 305.00
IUUC-Gma-042949 Glycine max 46.13 4.00e-73 265.00
IUUC-Ggo-045252 Gorilla gorilla 49.67 7.00e-83 298.00
IUUC-Hsa-046565 Homo sapiens 49.67 1.00e-82 297.00
IUUC-Hvu-047835 Hordeum vulgare 45.85 1.00e-74 270.00
IUUC-Itr-048587 Ictidomys tridecemlineatus 50.00 2.00e-83 300.00
IUUC-Kpa-049148 Komagataella pastoris 67.46 2.00e-122 429.00
IUUC-Lch-050421 Latimeria chalumnae 50.99 9.00e-84 301.00
IUUC-Lpe-051187 Leersia perrieri 45.03 4.00e-73 268.00
IUUC-Loc-052167 Lepisosteus oculatus 49.34 2.00e-83 300.00
IUUC-Lma-053250 Leptosphaeria maculans 54.18 7.00e-89 317.00
IUUC-Laf-054304 Loxodonta africana 50.00 2.00e-83 299.00
IUUC-Mcc-055519 Macaca mulatta 50.00 3.00e-83 300.00
IUUC-Meu-056439 Macropus eugenii 50.99 1.00e-84 303.00
IUUC-Mor-057241 Magnaporthe oryzae 54.30 7.00e-88 314.00
IUUC-Mpo-057373 Magnaporthe poae 49.32 7.00e-76 274.00
IUUC-Mtr-058412 Medicago truncatula 46.13 2.00e-70 256.00
IUUC-Mla-058966 Melampsora laricipopulina 48.49 7.00e-87 311.00
IUUC-Mga-060066 Meleagris gallopavo 52.05 3.00e-82 296.00
IUUC-Mvi-060290 Microbotryum violaceum 49.85 3.00e-87 315.00
IUUC-Mmr-060717 Microcebus murinus 50.33 4.00e-84 302.00
IUUC-Mdo-062496 Monodelphis domestica 50.66 4.00e-84 302.00
IUUC-Mmu-063490 Mus musculus 49.67 1.00e-83 300.00
IUUC-Mac-064519 Musa acuminata 46.98 1.00e-72 264.00
IUUC-Mpu-066601 Mustela putorius furo 50.00 1.00e-83 300.00
IUUC-Mlu-067501 Myotis lucifugus 49.67 6.00e-83 298.00
IUUC-Nfi-068360 Neosartorya fischeri 55.34 5.00e-76 275.00
IUUC-Ncr-068928 Neurospora crassa 55.12 6.00e-93 331.00
IUUC-Nle-069028 Nomascus leucogenys 49.34 1.00e-82 297.00
IUUC-Opr-070446 Ochotona princeps 50.68 2.00e-80 290.00
IUUC-Ont-071587 Oreochromis niloticus 51.49 3.00e-84 302.00
IUUC-Oan-073211 Ornithorhynchus anatinus 49.34 2.00e-82 296.00
IUUC-Ocu-074306 Oryctolagus cuniculus 49.67 4.00e-81 292.00
IUUC-Oba-075069 Oryza barthii 45.85 6.00e-74 268.00
IUUC-Obr-076667 Oryza brachyantha 46.18 3.00e-75 272.00
IUUC-Ogl-077208 Oryza glaberrima 45.85 6.00e-74 268.00
IUUC-Ogu-078513 Oryza glumaepatula 45.85 6.00e-74 268.00
IUUC-Oin-079094 Oryza indica 45.85 6.00e-74 268.00
IUUC-Olo-080473 Oryza longistaminata 45.85 6.00e-74 268.00
IUUC-Ome-081643 Oryza meridionalis 45.85 6.00e-74 268.00
IUUC-Oni-082589 Oryza nivara 45.85 6.00e-74 268.00
IUUC-Opu-083677 Oryza punctata 45.85 7.00e-74 268.00
IUUC-Oru-084537 Oryza rufipogon 45.85 6.00e-74 268.00
IUUC-Osa-085449 Oryza sativa 45.85 6.00e-74 268.00
IUUC-Ola-087226 Oryzias latipes 50.66 4.00e-84 302.00
IUUC-Olu-087893 Ostreococcus lucimarinus 45.55 6.00e-65 238.00
IUUC-Oga-088837 Otolemur garnettii 50.00 1.00e-83 300.00
IUUC-Oar-089594 Ovis aries 50.66 1.00e-83 300.00
IUUC-Ptr-091132 Pan troglodytes 49.67 5.00e-83 298.00
IUUC-Psi-093568 Pelodiscus sinensis 51.36 3.00e-82 296.00
IUUC-Pma-094756 Petromyzon marinus 52.83 9.00e-32 126.00
IUUC-Pno-094955 Phaeosphaeria nodorum 55.33 4.00e-89 318.00
IUUC-Ppa-095183 Physcomitrella patens 47.78 9.00e-74 267.00
IUUC-Pfo-096063 Poecilia formosa 50.99 3.00e-84 302.00
IUUC-Pab-098674 Pongo abelii 49.34 4.00e-82 295.00
IUUC-Pop-099402 Populus trichocarpa 46.98 5.00e-72 261.00
IUUC-Pca-100824 Procavia capensis 38.54 2.00e-57 214.00
IUUC-Ppe-101278 Prunus persica 47.00 4.00e-71 258.00
IUUC-Pva-103161 Pteropus vampyrus 46.03 4.00e-75 272.00
IUUC-Pgr-103573 Puccinia graminis 50.00 5.00e-89 318.00
IUUC-Ptt-103700 Puccinia triticina 50.96 1.00e-87 314.00
IUUC-Pte-104267 Pyrenophora teres 55.48 9.00e-90 320.00
IUUC-Pyt-104535 Pyrenophora triticirepentis 54.79 7.00e-87 311.00
IUUC-Rno-104833 Rattus norvegicus 49.67 4.00e-83 299.00
IUUC-Sce-106437 Saccharomyces cerevisiae 81.82 4.00e-140 488.00
IUUC-Sha-106611 Sarcophilus harrisii 50.99 1.00e-84 303.00
IUUC-Sja-107654 Schizosaccharomyces japonicus 57.24 7.00e-101 357.00
IUUC-Spo-108362 Schizosaccharomyces pombe 55.89 2.00e-97 346.00
IUUC-Smo-108797 Selaginella moellendorffii 47.51 2.00e-75 273.00
IUUC-Sit-110132 Setaria italica 46.51 5.00e-75 272.00
IUUC-Sly-111852 Solanum lycopersicum 45.82 1.00e-71 260.00
IUUC-Stu-112195 Solanum tuberosum 45.82 1.00e-71 260.00
IUUC-Sbi-114229 Sorghum bicolor 46.84 2.00e-76 276.00
IUUC-Sre-114898 Sporisorium reilianum 46.11 7.00e-89 318.00
IUUC-Ssc-115995 Sus scrofa 56.82 2.00e-43 166.00
IUUC-Tgu-116793 Taeniopygia guttata 50.33 4.00e-80 289.00
IUUC-Tru-117797 Takifugu rubripes 50.00 1.00e-83 300.00
IUUC-Tni-120366 Tetraodon nigroviridis 51.16 1.00e-83 300.00
IUUC-Tca-121242 Theobroma cacao 45.67 9.00e-72 261.00
IUUC-Tre-121899 Trichoderma reesei 51.47 9.00e-89 317.00
IUUC-Tvi-122380 Trichoderma virens 51.96 2.00e-89 319.00
IUUC-Tae-123998 Triticum aestivum 46.51 2.00e-75 273.00
IUUC-Tur-126202 Triticum urartu 46.18 9.00e-75 271.00
IUUC-Tme-127181 Tuber melanosporum 57.32 5.00e-103 365.00
IUUC-Ttr-128448 Tursiops truncatus 49.80 2.00e-66 243.00
IUUC-Uma-129661 Ustilago maydis 46.22 4.00e-89 319.00
IUUC-Vda-129666 Verticillium dahliae 55.63 5.00e-91 325.00
IUUC-Vpa-130318 Vicugna pacos 50.00 3.00e-83 299.00
IUUC-Vvi-130868 Vitis vinifera 46.98 5.00e-73 265.00
IUUC-Xtr-131859 Xenopus tropicalis 49.01 2.00e-81 293.00
IUUC-Xma-133898 Xiphophorus maculatus 50.99 1.00e-84 303.00
IUUC-Yli-134559 Yarrowia lipolytica 66.45 8.00e-119 417.00
Created Date 25-Jun-2017

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