iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-117824

Ensembl Protein ID

ENSTRUP00000002190.1

UniProt Accession

H2RPX6; H2RPX6_TAKRU

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000000921.1	ENSTRUT00000002198.1	ENSTRUP00000002189.1
ENSTRUG00000000921.1	ENSTRUT00000002199.1	ENSTRUP00000002190.1
ENSTRUG00000000921.1	ENSTRUT00000002200.1	ENSTRUP00000002191.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.60e-33	113.8	227	262
UBD/Beta-Prp	7.20e-56	190.8	286	549

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlrtgv 34
           gHt+++t+la    + tl+++Gs D+ti+vW lrt+ 
   Q: 227  GHTAEITDLAVnyeN-TLIAAGSCDKTIRVWCLRTCA 262
           8*******9998543.*****************9975 PP

UBD/Beta-Prp

   S: 21   dksllatgsrdgtikvwdvttgkllrslsgheae..........vtavkfspdgkilvtgseDrtikvwdls..tgkcvhtlkghedsv 97
           +k++++++++d+t+  w+++  +   ++s+++ +          + + +fsp g +l+tgs+D++i+++ l   +++ ++ l++h+d+v
   Q: 286  SKRYMLSTGTDATLHFWQWDVDSI--KFSDQSHKfterprpgvqTVCSSFSPGGMFLATGSTDNVIRIYYLGsgSPEKISELHEHTDKV 372
           799**************9999888..66666666667888887788889********************665448899*********** PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqclee.................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktg 169
            s++f+ sg+++vsGs+d t+r+w+l+++q  ++                  +s  +  v++v+++  + ++v++ ++  +++W++ tg
   Q: 373  DSIQFCHSGERFVSGSQDGTARIWKLHQRQQWKSillkmsatlpgaelmveEESFSKPKVTMVAWDRHDGMVVTAVNNCLLKVWNSYTG 461
           ********************************99***************9988888889****************************** PP
   S: 170  kllrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriWd 250
           +ll+ l+g h+  v  l+   fds  + ++s+++dg v +wdlq+g+ v+ + +         v + +f+p+++ ++++ s+g + i+ 
   Q: 462  ELLHILKG-HEAEVFVLEphpFDS--RIMLSAGHDGNVYMWDLQRGTRVMHFFNMIegqghGAVFDCKFTPDGQSFACTDSHGHLLIFG 547
           *******9.*********877777..9********************987776654445556777789999999999999999998876 PP
   S: 251  lr 252
             
   Q: 548  FG 549
           55 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

TTDDSMAKNR NISLVESELY YLISRFLTTG PCRRAAEVLI SELEEHQLLP RRLDWLGNEH 60
QRTYEDVVAA NRHITPEHLL RICMQIGPIL DKAVPSCVSG VQTLLGTGKQ SALRTIKDSE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCACGGACG ATTCAATGGC AAAAAATCGG AATATTTCGC TCGTTGAGTC GGGTAAGCTA 60
AGTAAAGCCC ACCGATAGCT GAAATTTGGT CCAGTATCGT TGTCGCCGAT TGATTTGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-010718	Astyanax mexicanus	70.02	0.00e+00	1203.00
IUUC-Cja-019966	Callithrix jacchus	57.45	0.00e+00	1659.00
IUUC-Cre-023003	Chlamydomonas reinhardtii	35.66	5.00e-34	139.00
IUUC-Cho-024690	Choloepus hoffmanni	73.37	1.00e-166	581.00
IUUC-Cin-025553	Ciona intestinalis	37.93	1.00e-108	387.00
IUUC-Itr-047962	Ictidomys tridecemlineatus	59.26	0.00e+00	689.00
IUUC-Loc-052853	Lepisosteus oculatus	65.81	0.00e+00	1784.00
IUUC-Mmu-064075	Mus musculus	56.05	0.00e+00	1675.00
IUUC-Oba-075709	Oryza barthii	30.09	4.00e-59	224.00
IUUC-Ogl-077493	Oryza glaberrima	26.33	2.00e-29	125.00
IUUC-Oru-085195	Oryza rufipogon	30.09	4.00e-59	224.00
IUUC-Pfo-097318	Poecilia formosa	72.82	0.00e+00	2063.00
IUUC-Pop-099185	Populus trichocarpa	31.93	3.00e-70	261.00
IUUC-Ssc-115461	Sus scrofa	52.10	0.00e+00	1405.00
IUUC-Tni-120656	Tetraodon nigroviridis	85.71	0.00e+00	2432.00
IUUC-Vpa-130160	Vicugna pacos	55.22	0.00e+00	1307.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence