iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Yli-134362

Ensembl Protein ID

CAG79134

UniProt Accession

Q6C709; PRP46_YARLI

Genbank Protein ID

CAG79134.2

Protein Name

Pre-mRNA-splicing factor PRP46; Pre-mRNA-processing protein 46

Genbank Nucleotide ID

CR382131

Gene Name

PRP46; YALI0E04697g

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
YALI0_E04697g	CAG79134	CAG79134

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.50e-37	122.9	130	166
UBD/Beta-Prp	6.60e-60	201.2	131	421

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH+++v++++  ++   +++Gs D+tik+WDl tg+l
   Q: 130  GHQGWVRSVCVePEnQWFATGSADKTIKIWDLATGKL 166
           8***********88799****************9986 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdkl 109
           h++ +++v++ p+++++atgs+d+tik+wd+ tgkl  +l gh  +v+a+  sp+ +++ +g+eD+++k wdl+t+k v++++gh + v+sl+++p+ d+l
   Q: 131  HQGWVRSVCVEPENQWFATGSADKTIKIWDLATGKLRLTLTGHIMGVRALGVSPRHPYMFSGGEDKMVKCWDLETNKVVRHYHGHLSAVYSLDIHPTLDVL 231
           6667888********************************************************************************************** PP
   S: 110  vsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlq 210
           vs+++d ++rvwd++t+  +  +lsgh++++n v+++ ++  ++++s+D+tvrlW+l+ gk ++tlt  h++sv+ l+++++ + + ++s +++ k w + 
   Q: 232  VSAGRDAVARVWDIRTRDPVV-VLSGHKSTINRVKFQASEPQVITASADETVRLWNLQAGKTMTTLTH-HKKSVRGLTLHPEEFTFSTASANSS-KQWKCP 329
           *********************.*********************************************9.*****************99999988.9***** PP
   S: 211  tgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhn........ssvisvavlsfgdnvlvlgsedskvniwklkk 296
           +g+ v  + ++++ ++ + +  +d+ + sg++ gsi ++d ++g + +++q           + +  ++ ++ ++  l+++++d+++++w  k 
   Q: 330  EGDLVLNYDDQNAIINTLSVN-QDNVMFSGGDNGSIGFYDWKTGHMFQSTQSIPipgsieseNGIFDSS-FDKTGLRLITCEADKSIKMWREKP 421
           ********************9.9*****************99998888888766776666533333333.48888999************8765 PP

Organism

Yarrowia lipolytica

Functional Description
(View)

Involved in pre-mRNA splicing and required for cell cycle progression at G2/M.

Protein Sequence
(Fasta)

MPVAKDLFPE YGTLATGENE PSRNIRRAQK LREFQNLELP PYLAKQVAAK MAEKGLAVEA 60
TGGVAVQRIA GGSQSGQKAL MGASSSALTK HTPSASQPTT HDSLTNLGAN LTQSKPAWHA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCTGTCG CCAAAGACCT GTTTCCAGAG TATGGTACTC TCGCGACCGG CGAAAATGAA 60
CCCTCTCGAA ATATCCGACG TGCTCAAAAA CTCAGGGAGT TCCAGAACCT CGAACTTCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0507--mRNA processing
KW-0508--mRNA splicing
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0747--Spliceosome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0071014--C:post-mRNA release spliceosomal complex
GO:0071011--C:precatalytic spliceosome
GO:0000974--C:Prp19 complex
GO:0045292--P:mRNA cis splicing, via spliceosome
GO:0000398--P:mRNA splicing, via spliceosome

KEGG

yli:YALI0E04697g

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000084	Aegilops tauschii	53.39	3.00e-113	399.00
IUUC-Aml-001605	Ailuropoda melanoleuca	58.84	3.00e-121	426.00
IUUC-Atr-002757	Amborella trichopoda	58.93	9.00e-116	408.00
IUUC-Apl-003198	Anas platyrhynchos	59.15	2.00e-121	427.00
IUUC-Aca-004683	Anolis carolinensis	59.45	2.00e-122	430.00
IUUC-Aly-005775	Arabidopsis lyrata	53.33	2.00e-120	423.00
IUUC-Ath-007460	Arabidopsis thaliana	54.05	7.00e-121	425.00
IUUC-Ago-007884	Ashbya gossypii	49.75	1.00e-119	420.00
IUUC-Acl-008153	Aspergillus clavatus	63.88	3.00e-127	446.00
IUUC-Afl-008384	Aspergillus flavus	55.50	2.00e-129	453.00
IUUC-Afu-009045	Aspergillus fumigatus	63.28	3.00e-126	442.00
IUUC-Ani-009229	Aspergillus nidulans	60.43	1.00e-125	441.00
IUUC-Ang-009812	Aspergillus niger	67.95	7.00e-124	434.00
IUUC-Aor-010059	Aspergillus oryzae	55.50	2.00e-129	453.00
IUUC-Ate-010351	Aspergillus terreus	65.85	1.00e-135	474.00
IUUC-Ame-011613	Astyanax mexicanus	37.91	2.00e-66	244.00
IUUC-Bgr-012042	Blumeria graminis	54.91	2.00e-142	496.00
IUUC-Bta-012406	Bos taurus	58.84	3.00e-121	426.00
IUUC-Bci-013760	Botrytis cinerea	65.62	1.00e-137	480.00
IUUC-Bdi-014776	Brachypodium distachyon	58.07	2.00e-116	410.00
IUUC-Bol-016189	Brassica oleracea	60.25	1.00e-120	424.00
IUUC-Bra-018044	Brassica rapa	60.25	8.00e-121	424.00
IUUC-Cel-018651	Caenorhabditis elegans	62.77	3.00e-126	443.00
IUUC-Cja-019974	Callithrix jacchus	52.08	9.00e-123	431.00
IUUC-Cfa-021085	Canis familiaris	58.84	2.00e-121	426.00
IUUC-Cpo-021458	Cavia porcellus	59.15	7.00e-122	428.00
IUUC-Cre-022880	Chlamydomonas reinhardtii	59.01	3.00e-121	426.00
IUUC-Csa-023883	Chlorocebus sabaeus	51.83	1.00e-122	431.00
IUUC-Cho-024623	Choloepus hoffmanni	58.90	8.00e-119	418.00
IUUC-Cin-025190	Ciona intestinalis	59.08	1.00e-123	434.00
IUUC-Csv-026367	Ciona savignyi	59.08	7.00e-123	431.00
IUUC-Cgl-026499	Colletotrichum gloeosporioides	57.83	1.00e-137	481.00
IUUC-Cne-027069	Cryptococcus neoformans	51.67	4.00e-121	426.00
IUUC-Cme-027233	Cyanidioschyzon merolae	28.83	7.00e-34	135.00
IUUC-Dre-028260	Danio rerio	53.90	2.00e-125	440.00
IUUC-Dno-029112	Dasypus novemcinctus	59.15	1.00e-121	428.00
IUUC-Dor-031118	Dipodomys ordii	52.88	2.00e-122	429.00
IUUC-Dse-031493	Dothistroma septosporum	53.08	4.00e-127	446.00
IUUC-Dme-032138	Drosophila melanogaster	56.52	3.00e-117	413.00
IUUC-Ete-032411	Echinops telfairi	50.14	9.00e-100	355.00
IUUC-Eca-033521	Equus caballus	51.12	7.00e-122	428.00
IUUC-Eeu-035249	Erinaceus europaeus	50.61	8.00e-96	342.00
IUUC-Fca-036358	Felis catus	58.84	2.00e-121	427.00
IUUC-Fal-036933	Ficedula albicollis	59.15	1.00e-121	427.00
IUUC-Fox-037713	Fusarium oxysporum	58.92	6.00e-138	481.00
IUUC-Fso-038380	Fusarium solani	64.88	4.00e-135	472.00
IUUC-Gmo-039133	Gadus morhua	53.85	1.00e-125	441.00
IUUC-Ggr-039915	Gaeumannomyces graminis	64.83	7.00e-126	442.00
IUUC-Gga-041176	Gallus gallus	59.15	2.00e-121	426.00
IUUC-Gac-042344	Gasterosteus aculeatus	52.55	4.00e-122	429.00
IUUC-Gma-043328	Glycine max	48.97	1.00e-116	410.00
IUUC-Ggo-044478	Gorilla gorilla	51.83	3.00e-122	430.00
IUUC-Hsa-046037	Homo sapiens	51.83	5.00e-122	429.00
IUUC-Hvu-047349	Hordeum vulgare	58.39	6.00e-117	412.00
IUUC-Itr-048390	Ictidomys tridecemlineatus	51.71	2.00e-122	430.00
IUUC-Kpa-049343	Komagataella pastoris	61.92	3.00e-131	459.00
IUUC-Lch-049830	Latimeria chalumnae	52.36	1.00e-123	434.00
IUUC-Lpe-051442	Leersia perrieri	57.45	2.00e-116	410.00
IUUC-Loc-051794	Lepisosteus oculatus	54.12	7.00e-121	425.00
IUUC-Lma-053137	Leptosphaeria maculans	57.38	1.00e-130	457.00
IUUC-Laf-053471	Loxodonta africana	59.15	8.00e-122	428.00
IUUC-Mcc-055627	Macaca mulatta	51.83	1.00e-122	431.00
IUUC-Meu-056148	Macropus eugenii	57.32	4.00e-118	416.00
IUUC-Mor-056960	Magnaporthe oryzae	64.62	1.00e-132	464.00
IUUC-Mtr-057816	Medicago truncatula	58.07	8.00e-117	411.00
IUUC-Mla-059031	Melampsora laricipopulina	63.52	2.00e-119	420.00
IUUC-Mga-059337	Meleagris gallopavo	59.15	3.00e-121	426.00
IUUC-Mvi-060217	Microbotryum violaceum	59.64	8.00e-121	425.00
IUUC-Mmr-061018	Microcebus murinus	51.46	3.00e-122	429.00
IUUC-Mdo-062863	Monodelphis domestica	59.32	2.00e-120	424.00
IUUC-Mmu-063988	Mus musculus	48.04	9.00e-122	428.00
IUUC-Mac-064459	Musa acuminata	57.05	2.00e-112	397.00
IUUC-Mpu-066559	Mustela putorius furo	58.84	3.00e-121	426.00
IUUC-Mlu-067361	Myotis lucifugus	59.15	1.00e-121	427.00
IUUC-Nfi-068492	Neosartorya fischeri	63.58	2.00e-126	443.00
IUUC-Ncr-068808	Neurospora crassa	61.45	3.00e-135	473.00
IUUC-Nle-069875	Nomascus leucogenys	51.83	3.00e-122	430.00
IUUC-Opr-070462	Ochotona princeps	58.65	2.00e-96	344.00
IUUC-Ont-071365	Oreochromis niloticus	53.40	1.00e-124	437.00
IUUC-Oan-072708	Ornithorhynchus anatinus	59.15	9.00e-122	428.00
IUUC-Ocu-074594	Oryctolagus cuniculus	59.15	1.00e-121	427.00
IUUC-Oba-075570	Oryza barthii	57.45	4.00e-116	409.00
IUUC-Obr-076366	Oryza brachyantha	59.46	3.00e-84	302.00
IUUC-Ogl-077153	Oryza glaberrima	57.63	1.00e-115	407.00
IUUC-Ogu-078540	Oryza glumaepatula	57.45	4.00e-116	409.00
IUUC-Oin-079612	Oryza indica	56.57	5.00e-114	402.00
IUUC-Olo-081077	Oryza longistaminata	56.57	5.00e-114	402.00
IUUC-Ome-081236	Oryza meridionalis	56.27	7.00e-114	402.00
IUUC-Oni-082499	Oryza nivara	57.45	4.00e-116	409.00
IUUC-Opu-083499	Oryza punctata	56.57	4.00e-114	402.00
IUUC-Oru-084276	Oryza rufipogon	57.45	4.00e-116	409.00
IUUC-Osa-085849	Oryza sativa	57.45	4.00e-116	409.00
IUUC-Ola-086655	Oryzias latipes	53.06	2.00e-123	433.00
IUUC-Olu-087637	Ostreococcus lucimarinus	54.57	3.00e-119	419.00
IUUC-Oga-087934	Otolemur garnettii	51.83	9.00e-123	431.00
IUUC-Oar-090185	Ovis aries	58.84	3.00e-121	426.00
IUUC-Ptr-091198	Pan troglodytes	51.83	3.00e-122	430.00
IUUC-Pan-092622	Papio anubis	51.83	1.00e-122	431.00
IUUC-Psi-093320	Pelodiscus sinensis	59.15	1.00e-121	427.00
IUUC-Pma-094638	Petromyzon marinus	52.61	1.00e-123	434.00
IUUC-Pno-094826	Phaeosphaeria nodorum	52.69	3.00e-112	396.00
IUUC-Ppa-095783	Physcomitrella patens	60.26	9.00e-116	408.00
IUUC-Pfo-096894	Poecilia formosa	53.64	4.00e-124	436.00
IUUC-Pab-098020	Pongo abelii	51.83	2.00e-122	430.00
IUUC-Pop-099180	Populus trichocarpa	58.01	4.00e-112	396.00
IUUC-Pca-100909	Procavia capensis	62.02	1.00e-99	354.00
IUUC-Ppe-101346	Prunus persica	48.67	1.00e-118	417.00
IUUC-Pva-102167	Pteropus vampyrus	51.83	6.00e-101	358.00
IUUC-Pgr-103516	Puccinia graminis	62.87	8.00e-119	418.00
IUUC-Ptt-103738	Puccinia triticina	52.40	1.00e-119	421.00
IUUC-Pte-104352	Pyrenophora teres	59.62	7.00e-136	475.00
IUUC-Pyt-104632	Pyrenophora triticirepentis	59.89	1.00e-136	478.00
IUUC-Rno-105291	Rattus norvegicus	47.51	1.00e-121	428.00
IUUC-Sce-106204	Saccharomyces cerevisiae	54.36	3.00e-117	413.00
IUUC-Sha-106943	Sarcophilus harrisii	58.20	2.00e-117	414.00
IUUC-Sja-107659	Schizosaccharomyces japonicus	66.57	2.00e-129	454.00
IUUC-Spo-108049	Schizosaccharomyces pombe	54.44	9.00e-133	464.00
IUUC-Smo-109043	Selaginella moellendorffii	59.32	3.00e-119	419.00
IUUC-Sit-110431	Setaria italica	58.07	2.00e-116	410.00
IUUC-Sly-111391	Solanum lycopersicum	58.01	4.00e-111	392.00
IUUC-Stu-112364	Solanum tuberosum	52.79	4.00e-92	328.00
IUUC-Sar-113450	Sorex araneus	59.15	4.00e-121	426.00
IUUC-Sbi-113829	Sorghum bicolor	47.23	2.00e-115	407.00
IUUC-Sre-115153	Sporisorium reilianum	58.90	4.00e-114	402.00
IUUC-Ssc-116274	Sus scrofa	59.15	1.00e-121	428.00
IUUC-Tgu-117417	Taeniopygia guttata	59.15	1.00e-121	427.00
IUUC-Tru-117615	Takifugu rubripes	52.10	2.00e-117	414.00
IUUC-Tsy-119480	Tarsius syrichta	59.15	1.00e-121	427.00
IUUC-Tni-119847	Tetraodon nigroviridis	52.35	1.00e-123	434.00
IUUC-Tca-121287	Theobroma cacao	47.71	2.00e-117	413.00
IUUC-Tre-122010	Trichoderma reesei	64.88	1.00e-135	474.00
IUUC-Tvi-122475	Trichoderma virens	62.32	1.00e-134	471.00
IUUC-Tae-124243	Triticum aestivum	57.62	1.00e-116	411.00
IUUC-Tur-126116	Triticum urartu	47.52	7.00e-85	305.00
IUUC-Tme-126992	Tuber melanosporum	63.91	2.00e-134	470.00
IUUC-Tbe-127803	Tupaia belangeri	63.16	2.00e-97	347.00
IUUC-Ttr-128933	Tursiops truncatus	59.15	1.00e-121	427.00
IUUC-Uma-129447	Ustilago maydis	57.93	3.00e-115	406.00
IUUC-Vda-129780	Verticillium dahliae	64.55	5.00e-137	479.00
IUUC-Vpa-130557	Vicugna pacos	39.39	2.00e-38	151.00
IUUC-Vvi-130918	Vitis vinifera	57.37	1.00e-111	394.00
IUUC-Xtr-132409	Xenopus tropicalis	58.54	2.00e-120	423.00
IUUC-Xma-133420	Xiphophorus maculatus	53.40	3.00e-124	436.00
IUUC-Zma-135804	Zea mays	55.96	4.00e-113	399.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence