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Tag Content
UUCD2 ID IUUC-Cfa-021189
UUCD1 version UUC-CaF-00453
Ensembl Protein ID ENSCAFP00000027368.3
UniProt Accession E2RMN1; E2RMN1_CANLF
Genbank Protein ID ENSCAFP00000027368
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAEX03026836
Gene Name CUL4B
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCAFG00000018537.3 ENSCAFT00000029435.3 ENSCAFP00000027368.3
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/Cullin 1.00e-220 734.9 288 883
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/Cullin
   S: 1    klreavkkilrqesvkkeyeelytavynlclskvgaklYkklkevleefi.kqvkkkveesedeq.lLktynreWekfreqlkvlrkif 87
           kl+eav++i++++s+k+++eely+av+nlc++k++a+lYk+l++++e++i +q+++ +e+s d+  +Lk++ ++W+++++q+ ++r+if
   Q: 288  KLKEAVEAIQNSTSIKYNLEELYQAVENLCSYKISANLYKQLRQICEDHIkAQIHQFREDSLDSVlFLKKIDKCWQNHCRQMIMIRSIF 376
           589***********************************************99************************************* PP
   S: 88   ayldrtyvkkskkvsevrkLaldlwrkeived..ikkrllelllklieaeRkgeavdrrllsgvveslveLslnklaiykesFEakfle 174
           ++ldrtyv +++++ ++++++l+l+r +i++d  +++++++ +l lie+eR+gea+dr+ll+++ ++l++L     +iy++sFE++fle
   Q: 377  LFLDRTYVLQNSMLPSIWDMGLELFRAHIISDqkVQNKTIDGILLLIERERNGEAIDRSLLRSLLSMLSDL-----QIYQDSFEQRFLE 460
           ********************************9**********************************9998.....9************ PP
   S: 175  atqefykaesaeflqenevdeYlkkvearlneeeeraaryleestetkLlevvekeliakhlesll.aelvallrdkktedlsrmykLl 262
           +t+++y+ae ++++qe+ev eYl++v++rl+ee +r+ +yl+++t+++L+++vek+l+ +hl+++l ++l++ll++++ +dls++y+L+
   Q: 461  ETNRLYAAEGQKLMQEREVPEYLHHVNKRLEEEADRLITYLDQTTQKSLIATVEKQLLGEHLTAILqKGLNNLLDENRIQDLSLLYQLF 549
           ****************************************************************9989********************* PP
   S: 263  srvlngleellkeleshikeqgkaaltaeekekdpkkyVerllelknklqklvseaFnndakFlkaldkafetfvnknsvlkaaksp.E 350
           srv+ g++ ll+++ ++ik  g+++++++ek+k+   +V++ll++k+k++++++ +F +++kF++a+++afetf+nk+     +++p E
   Q: 550  SRVRGGVQVLLQQWIEYIKAFGSTIVINPEKDKT---MVQELLDFKDKVDHIIDICFLKNEKFINAMKEAFETFINKR-----PNKPaE 630
           **********************************...*****************************************.....66666* PP
   S: 351  llAryiDqlLrksskglteeeleaqldkvllvfkyisekdvFekyYkkhLakRLlsgksasseaEesviekLkeecgaeftskLerMfq 439
           l+A+y+D++Lr+++k++t+eele++ldk++++f++i +kdvFe++Ykk+LakRLl+gksas +aE+s+++kLk+ecga+ftskLe+Mf+
   Q: 631  LIAKYVDSKLRAGNKEATDEELEKMLDKIMIIFRFIYGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFK 719
           ***************************************************************************************** PP
   S: 440  dlkvSedlnrqFkeekenteesesvelsvlvLsagaWptasetekvsLPaelektiekfeefYlekhsgRkLqWqhtlgraelkaelkk 528
           d+++S+d+++qFk+ ++n++   ++el+v++L++g+Wpt+  +e v+LP+e+ k++e+f++fYl khsgRkLqWq tlg++ lkae+k+
   Q: 720  DMELSKDIMIQFKQYMQNQNVPGNIELTVNILTMGYWPTYVPME-VHLPPEMVKLQEIFKTFYLGKHSGRKLQWQSTLGHCVLKAEFKE 807
           ******************************************99.******************************************** PP
   S: 529  gkyelqVstfQmavLLafnnsekvsveelkkatelpeeeLrrtlqsLvsskkqvlkkepeskeieeedlfsvNqef 604
           gk+elqVs fQ++vLL+fn+ e++s+ee+k+at++++ eLrrtlqsL+++k++vl k+p++k+ie++d+f++N++f
   Q: 808  GKKELQVSLFQTLVLLMFNEGEEFSLEEIKQATGIEDGELRRTLQSLACGKARVLAKNPKGKDIEDGDKFICNDDF 883
           **************************************************************************98 PP
   
Organism Canis familiaris
Protein Sequence
(Fasta)
MSQPSESGNG RDDAAISEDN DTFLNNACRR NIFRILLNKQ YLLYGRKIPP VDDKSSVSLS 60
ICPQTSPCSE MSEDDSKPST LENPRDQKRE KGFSSPNPSA AAAAQEVRSA TDGNTSTTPP 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cfa-021189|E3,Cullin|Canis familiaris
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TCCTCCAAAG ATGGACCATG TCACAGCCCT CTGAATCAGG GAATGGAAGA GATGATGCAG 60
CCATCTCAGA AGATAATGGT GAGTAAATAA ACTAGTAAAA GTCAAATGAG GTGAGGTATC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cfa-021189|E3,Cullin|Canis familiaris
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom
PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2
Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8
SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8
Gene Ontology

GO:0031465--C:Cul4B-RING E3 ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005654--C:nucleoplasm
GO:0003684--F:damaged DNA binding
GO:0031625--F:ubiquitin protein ligase binding
GO:0006974--P:cellular response to DNA damage stimulus
GO:0035518--P:histone H2A monoubiquitination
GO:1900087--P:positive regulation of G1/S transition of mitotic cell cycle
GO:0045732--P:positive regulation of protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0070914--P:UV-damage excision repair
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000285 Aegilops tauschii 57.61 0.00e+00 828.00
IUUC-Aml-002062 Ailuropoda melanoleuca 99.55 0.00e+00 1715.00
IUUC-Atr-002727 Amborella trichopoda 58.21 0.00e+00 807.00
IUUC-Apl-004157 Anas platyrhynchos 88.69 0.00e+00 1518.00
IUUC-Aca-004430 Anolis carolinensis 92.41 0.00e+00 1458.00
IUUC-Aly-006547 Arabidopsis lyrata 59.12 0.00e+00 814.00
IUUC-Ath-006748 Arabidopsis thaliana 57.22 0.00e+00 808.00
IUUC-Acl-008359 Aspergillus clavatus 36.07 8.00e-125 441.00
IUUC-Afl-008567 Aspergillus flavus 37.98 4.00e-136 479.00
IUUC-Afu-008833 Aspergillus fumigatus 38.04 1.00e-131 464.00
IUUC-Ani-009373 Aspergillus nidulans 39.14 7.00e-138 484.00
IUUC-Ang-009622 Aspergillus niger 39.31 2.00e-134 473.00
IUUC-Aor-010241 Aspergillus oryzae 37.77 8.00e-132 464.00
IUUC-Ate-010251 Aspergillus terreus 39.03 1.00e-138 487.00
IUUC-Ame-011580 Astyanax mexicanus 84.46 0.00e+00 1426.00
IUUC-Bgr-012219 Blumeria graminis 37.04 2.00e-116 413.00
IUUC-Bta-013244 Bos taurus 97.98 0.00e+00 1665.00
IUUC-Bci-013744 Botrytis cinerea 40.08 7.00e-129 454.00
IUUC-Bdi-014223 Brachypodium distachyon 55.60 0.00e+00 825.00
IUUC-Bol-016036 Brassica oleracea 58.34 0.00e+00 833.00
IUUC-Bra-017794 Brassica rapa 58.43 0.00e+00 833.00
IUUC-Cja-019180 Callithrix jacchus 99.44 0.00e+00 1702.00
IUUC-Cpo-021928 Cavia porcellus 98.88 0.00e+00 1677.00
IUUC-Cre-022739 Chlamydomonas reinhardtii 46.35 2.00e-175 609.00
IUUC-Csa-023831 Chlorocebus sabaeus 99.55 0.00e+00 1703.00
IUUC-Cho-024959 Choloepus hoffmanni 96.45 0.00e+00 1027.00
IUUC-Cgl-026761 Colletotrichum gloeosporioides 39.97 4.00e-127 449.00
IUUC-Dre-027916 Danio rerio 89.03 0.00e+00 1421.00
IUUC-Dno-029483 Dasypus novemcinctus 89.57 0.00e+00 1536.00
IUUC-Dse-031159 Dothistroma septosporum 36.40 1.00e-123 437.00
IUUC-Dme-031652 Drosophila melanogaster 64.71 0.00e+00 942.00
IUUC-Ete-032775 Echinops telfairi 87.19 0.00e+00 1386.00
IUUC-Eca-033952 Equus caballus 96.87 0.00e+00 1655.00
IUUC-Eeu-034767 Erinaceus europaeus 92.95 0.00e+00 1508.00
IUUC-Fca-036211 Felis catus 98.47 0.00e+00 1519.00
IUUC-Fal-037248 Ficedula albicollis 89.57 0.00e+00 1519.00
IUUC-Fox-037854 Fusarium oxysporum 38.90 2.00e-123 437.00
IUUC-Fso-038138 Fusarium solani 39.00 5.00e-127 448.00
IUUC-Gmo-038754 Gadus morhua 88.62 0.00e+00 1405.00
IUUC-Ggr-040003 Gaeumannomyces graminis 36.68 3.00e-106 379.00
IUUC-Gga-041002 Gallus gallus 90.12 0.00e+00 1533.00
IUUC-Gac-041555 Gasterosteus aculeatus 85.58 0.00e+00 1400.00
IUUC-Gma-043960 Glycine max 59.66 0.00e+00 843.00
IUUC-Ggo-045468 Gorilla gorilla 99.19 0.00e+00 1640.00
IUUC-Hsa-046848 Homo sapiens 99.22 0.00e+00 1704.00
IUUC-Itr-048365 Ictidomys tridecemlineatus 98.54 0.00e+00 1672.00
IUUC-Lch-049858 Latimeria chalumnae 85.97 0.00e+00 1496.00
IUUC-Lpe-051446 Leersia perrieri 56.61 0.00e+00 821.00
IUUC-Loc-052415 Lepisosteus oculatus 87.12 0.00e+00 1438.00
IUUC-Lma-053080 Leptosphaeria maculans 36.85 2.00e-135 476.00
IUUC-Laf-053701 Loxodonta africana 98.43 0.00e+00 1688.00
IUUC-Mcc-055538 Macaca mulatta 97.53 0.00e+00 1657.00
IUUC-Mor-057102 Magnaporthe oryzae 36.59 9.00e-119 421.00
IUUC-Mpo-057342 Magnaporthe poae 37.62 1.00e-103 370.00
IUUC-Mtr-058660 Medicago truncatula 57.83 0.00e+00 832.00
IUUC-Mla-058936 Melampsora laricipopulina 39.46 2.00e-114 406.00
IUUC-Mga-059754 Meleagris gallopavo 90.03 0.00e+00 1524.00
IUUC-Mvi-060455 Microbotryum violaceum 41.96 5.00e-146 511.00
IUUC-Mmr-060870 Microcebus murinus 98.54 0.00e+00 1691.00
IUUC-Mdo-062015 Monodelphis domestica 91.95 0.00e+00 1482.00
IUUC-Mmu-063751 Mus musculus 96.80 0.00e+00 1620.00
IUUC-Mac-064443 Musa acuminata 57.38 0.00e+00 841.00
IUUC-Mpu-065903 Mustela putorius furo 99.55 0.00e+00 1719.00
IUUC-Mlu-068213 Myotis lucifugus 98.32 0.00e+00 1691.00
IUUC-Nfi-068363 Neosartorya fischeri 38.51 6.00e-134 471.00
IUUC-Ncr-068950 Neurospora crassa 35.99 6.00e-119 422.00
IUUC-Nle-069480 Nomascus leucogenys 99.55 0.00e+00 1703.00
IUUC-Opr-071164 Ochotona princeps 92.01 0.00e+00 647.00
IUUC-Ont-071562 Oreochromis niloticus 81.83 0.00e+00 1260.00
IUUC-Oan-073607 Ornithorhynchus anatinus 94.51 0.00e+00 1489.00
IUUC-Ocu-074446 Oryctolagus cuniculus 99.55 0.00e+00 1712.00
IUUC-Oba-075198 Oryza barthii 56.89 0.00e+00 825.00
IUUC-Obr-076095 Oryza brachyantha 56.89 0.00e+00 827.00
IUUC-Ogl-077032 Oryza glaberrima 56.89 0.00e+00 824.00
IUUC-Ogu-078051 Oryza glumaepatula 57.32 0.00e+00 826.00
IUUC-Oin-079399 Oryza indica 52.62 0.00e+00 726.00
IUUC-Olo-080988 Oryza longistaminata 56.05 0.00e+00 816.00
IUUC-Ome-081600 Oryza meridionalis 56.05 0.00e+00 816.00
IUUC-Oni-082623 Oryza nivara 56.19 0.00e+00 818.00
IUUC-Opu-083762 Oryza punctata 55.93 0.00e+00 817.00
IUUC-Oru-084499 Oryza rufipogon 56.89 0.00e+00 825.00
IUUC-Ola-087157 Oryzias latipes 81.77 0.00e+00 1408.00
IUUC-Olu-087650 Ostreococcus lucimarinus 48.29 0.00e+00 627.00
IUUC-Oga-088416 Otolemur garnettii 96.64 0.00e+00 1610.00
IUUC-Oar-090230 Ovis aries 94.82 0.00e+00 1724.00
IUUC-Ptr-091153 Pan troglodytes 99.64 0.00e+00 1658.00
IUUC-Pan-091729 Papio anubis 99.55 0.00e+00 1703.00
IUUC-Psi-093773 Pelodiscus sinensis 94.29 0.00e+00 1505.00
IUUC-Pma-094678 Petromyzon marinus 85.22 0.00e+00 1060.00
IUUC-Pno-094946 Phaeosphaeria nodorum 35.62 7.00e-113 401.00
IUUC-Ppa-095688 Physcomitrella patens 59.52 0.00e+00 882.00
IUUC-Pfo-096828 Poecilia formosa 89.12 0.00e+00 1421.00
IUUC-Pab-097816 Pongo abelii 91.39 0.00e+00 1524.00
IUUC-Pca-100858 Procavia capensis 78.41 0.00e+00 1256.00
IUUC-Ppe-101142 Prunus persica 59.81 0.00e+00 848.00
IUUC-Pva-102995 Pteropus vampyrus 92.24 0.00e+00 1582.00
IUUC-Pgr-103334 Puccinia graminis 37.41 1.00e-105 378.00
IUUC-Ptt-103903 Puccinia triticina 41.16 2.00e-97 350.00
IUUC-Pte-104167 Pyrenophora teres 36.91 6.00e-135 475.00
IUUC-Pyt-104736 Pyrenophora triticirepentis 36.84 1.00e-133 470.00
IUUC-Rno-106119 Rattus norvegicus 97.49 0.00e+00 1634.00
IUUC-Sha-106958 Sarcophilus harrisii 87.60 0.00e+00 1493.00
IUUC-Sja-107940 Schizosaccharomyces japonicus 34.24 6.00e-112 398.00
IUUC-Spo-108109 Schizosaccharomyces pombe 34.32 2.00e-111 397.00
IUUC-Ssl-108537 Sclerotinia sclerotiorum 39.44 1.00e-128 453.00
IUUC-Smo-108872 Selaginella moellendorffii 60.00 0.00e+00 908.00
IUUC-Sit-110626 Setaria italica 57.89 0.00e+00 827.00
IUUC-Sly-111497 Solanum lycopersicum 60.08 0.00e+00 852.00
IUUC-Sar-113581 Sorex araneus 85.58 0.00e+00 1049.00
IUUC-Sbi-113931 Sorghum bicolor 57.89 0.00e+00 827.00
IUUC-Sre-114943 Sporisorium reilianum 39.19 3.00e-129 456.00
IUUC-Tgu-116462 Taeniopygia guttata 89.24 0.00e+00 1510.00
IUUC-Tru-118299 Takifugu rubripes 88.61 0.00e+00 1418.00
IUUC-Tsy-119517 Tarsius syrichta 100.00 0.00e+00 726.00
IUUC-Tni-120811 Tetraodon nigroviridis 87.22 0.00e+00 1391.00
IUUC-Tca-121626 Theobroma cacao 59.55 0.00e+00 843.00
IUUC-Tae-123442 Triticum aestivum 57.61 0.00e+00 828.00
IUUC-Tur-126032 Triticum urartu 57.61 0.00e+00 825.00
IUUC-Tme-127162 Tuber melanosporum 41.32 1.00e-140 493.00
IUUC-Tbe-127658 Tupaia belangeri 95.98 0.00e+00 1602.00
IUUC-Ttr-129112 Tursiops truncatus 90.26 0.00e+00 1505.00
IUUC-Vda-129701 Verticillium dahliae 39.26 5.00e-135 475.00
IUUC-Vpa-130217 Vicugna pacos 90.16 0.00e+00 1507.00
IUUC-Vvi-131133 Vitis vinifera 59.61 0.00e+00 853.00
IUUC-Xtr-132724 Xenopus tropicalis 91.76 0.00e+00 1458.00
IUUC-Xma-134149 Xiphophorus maculatus 89.36 0.00e+00 1434.00
Created Date 25-Jun-2017

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