iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-007471

UUCD1 version

UUC-ArT-01448

Ensembl Protein ID

AT2G35930.1

UniProt Accession

Q84TG3; Q9SJ57; PUB23_ARATH

Genbank Protein ID

AAD21464.1; AEC09178.1; AAO64764.1; BAE99354.1

Protein Name

E3 ubiquitin-protein ligase PUB23; Plant U-box protein 23; RING-type E3 ubiquitin transferase PUB23; U-box domain-containing protein 23

Genbank Nucleotide ID

AC007017; CP002685; BT005829; AK227343

Gene Name

PUB23; At2g35930; F11F19.16

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT2G35930	AT2G35930.1	AT2G35930.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
Protein-protein Interaction
PINA	HINT
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/U-box	U-box	19826220

Classification

Family	E-value	Score	Start	End
E3 activity/RING/U-box	2.00e-34	118.3	11	84
E3 activity/RING/RING	0.062	14.7	18	56

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 1    evpeeflCpIslelMrdPvvlpsGitydrssIekwlasggk.tcPvtrqplteedlvPnltlrrliqawceens 73
           e+p++flCpIsle+M+dPv++++Gitydr sIekwl  g+k +cPvt+q +t+ dl+Pn+tlrrliq+wc  n+
   Q: 11   EIPPFFLCPISLEIMKDPVIVSTGITYDRDSIEKWLFAGKKnSCPVTKQDITDADLTPNHTLRRLIQSWCTLNA 84
           69**********************************888888****************************9876 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPl 44
           C+i le +kd p++++ g ++ +d ++kw     ++ k+ +CP+
   Q: 18   CPISLEIMKD-PVIVSTGITYDRDSIEKW----LFAGKKNSCPV 56
           **********.999***************....99********8 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

E3 ubiquitin-protein ligase that negatively regulates water stress response. May control in coordination with PUB23 a drought signaling pathway by ubiquitinating cytosolic RPN12a. Acts as negative regulator of the immunity triggered by the pathogen-associated molecular patterns (PAMPs), in association with PUB22 and PUB24.

Protein Sequence
(Fasta)

MSGGIMDEEI EIPPFFLCPI SLEIMKDPVI VSTGITYDRD SIEKWLFAGK KNSCPVTKQD 60
ITDADLTPNH TLRRLIQSWC TLNASYGVER IPTPRPPICK SEIEKLIRDS ASSHENQVKC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TATTTTCCGT GTTTTGACTT TTTTAATAAT TGTGAATTTT TGACATCTCC TTTATATTTA 60
AACCCAACCT CCTTTCTCTC TTCCTCCTAA CTTATTCAAA CCAATTCACA TCTTCCCAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0611--Plant defense
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0832--Ubl conjugation
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR003613--Ubox_domain
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51698--U_BOX

Pfam

PF04564--U-box

SMART

SM00504--Ubox

Gene Ontology

GO:0005829--C:cytosol
GO:0004842--F:ubiquitin-protein transferase activity
GO:0006952--P:defense response
GO:0051865--P:protein autoubiquitination
GO:0016567--P:protein ubiquitination
GO:0010200--P:response to chitin
GO:0009414--P:response to water deprivation

KEGG

ath:AT2G35930

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000639	Aegilops tauschii	46.82	9.00e-84	303.00
IUUC-Atr-002430	Amborella trichopoda	44.83	2.00e-99	355.00
IUUC-Aly-006194	Arabidopsis lyrata	96.56	0.00e+00	750.00
IUUC-Bdi-014627	Brachypodium distachyon	43.98	7.00e-86	310.00
IUUC-Bol-015782	Brassica oleracea	90.91	0.00e+00	712.00
IUUC-Bra-016841	Brassica rapa	90.51	0.00e+00	716.00
IUUC-Hvu-047293	Hordeum vulgare	45.99	2.00e-84	305.00
IUUC-Lpe-051695	Leersia perrieri	41.12	7.00e-67	247.00
IUUC-Mac-065005	Musa acuminata	45.37	6.00e-96	343.00
IUUC-Oba-075095	Oryza barthii	43.90	7.00e-74	270.00
IUUC-Obr-076623	Oryza brachyantha	41.32	8.00e-48	182.00
IUUC-Ogl-077664	Oryza glaberrima	45.79	4.00e-77	280.00
IUUC-Ome-081839	Oryza meridionalis	45.83	3.00e-85	307.00
IUUC-Opu-084067	Oryza punctata	46.23	2.00e-93	335.00
IUUC-Ppa-095659	Physcomitrella patens	33.33	3.00e-60	225.00
IUUC-Ppe-102059	Prunus persica	56.62	1.00e-141	495.00
IUUC-Sit-110734	Setaria italica	42.25	1.00e-81	296.00
IUUC-Sly-111579	Solanum lycopersicum	54.85	4.00e-121	427.00
IUUC-Sbi-114243	Sorghum bicolor	46.15	5.00e-86	310.00
IUUC-Tca-121107	Theobroma cacao	61.93	8.00e-150	522.00
IUUC-Tae-124810	Triticum aestivum	44.34	7.00e-93	333.00
IUUC-Uma-129650	Ustilago maydis	37.50	6.50e-02	30.80
IUUC-Vvi-131052	Vitis vinifera	57.69	1.00e-137	481.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence