• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Tag Content
iUUCD ID IUUC-Yli-134485
Ensembl Protein ID CAG81587
UniProt Accession Q6CDH0; NACA_YARLI
Genbank Protein ID CAG81587.1
Protein Name Nascent polypeptide-associated complex subunit alpha; Alpha-NAC
Genbank Nucleotide ID CR382129
Gene Name EGD2; YALI0C00605g
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
YALI0_C00605g CAG81587 CAG81587
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
UBD/Alpha-Helix/UBA 36.56 2.00e-18 87.00 IUUC-Sce-106371
UBD/Alpha-Helix/UBA 34.92 5.00e-19 88.60 IUUC-Spo-108121
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Yarrowia lipolytica
Functional Description
(View)

Functional Description


     Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
 Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
Protein Sequence
(Fasta)
MSAENKIEEI TEDQVPQIEE NSTIVIKKEE KAARALISKL NLQKVEGITR VVLKRTRQHI 60
FVIANPEVYK TPTGNSYVVF GEAQHEDMQA TARAAQIAAA QAQQAAAETG SVSEAAAAGE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Yli-134485|UBD,UBA|Yarrowia lipolytica
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGTGAGTACA AACAACGCAG AAAACCGCAA TTGAGCAGAA AACGACGAGA TATCGACAGA 60
TCATGGCTTG TTCAGATCGC TTGCTTCCCG TGGCTACACC ATAGCTCGCT AATTCGTTCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Yli-134485|UBD,UBA|Yarrowia lipolytica
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
Interpro

IPR016641--EGD2/NACA
IPR002715--Nas_poly-pep-assoc_cplx_dom
PROSITE

PS51151--NAC_AB
Pfam

PF01849--NAC
SMART

SM01407--NAC
Gene Ontology

GO:0005854--C:nascent polypeptide-associated complex
GO:0005634--C:nucleus
GO:0070300--F:phosphatidic acid binding
GO:0080025--F:phosphatidylinositol-3,5-bisphosphate binding
GO:0032266--F:phosphatidylinositol-3-phosphate binding
GO:0070273--F:phosphatidylinositol-4-phosphate binding
GO:0051083--P:'de novo' cotranslational protein folding
GO:0006620--P:posttranslational protein targeting to membrane
KEGG yli:YALI0C00605g
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-001167 Aegilops tauschii 31.65 3.00e-17 79.70
IUUC-Aml-002185 Ailuropoda melanoleuca 36.09 1.00e-20 94.40
IUUC-Atr-002586 Amborella trichopoda 58.54 2.00e-08 50.10
IUUC-Apl-003190 Anas platyrhynchos 41.27 2.00e-12 63.20
IUUC-Aca-005265 Anolis carolinensis 47.54 3.00e-15 73.20
IUUC-Aly-006488 Arabidopsis lyrata 36.48 3.00e-19 86.30
IUUC-Ath-007378 Arabidopsis thaliana 46.94 2.00e-11 60.10
IUUC-Ago-007936 Ashbya gossypii 39.27 1.00e-24 103.00
IUUC-Acl-008036 Aspergillus clavatus 35.58 5.00e-15 72.00
IUUC-Afl-008462 Aspergillus flavus 36.19 6.00e-16 75.10
IUUC-Afu-008832 Aspergillus fumigatus 49.15 3.00e-14 69.30
IUUC-Ani-009246 Aspergillus nidulans 35.85 9.00e-16 74.70
IUUC-Ang-009808 Aspergillus niger 44.44 1.00e-14 70.50
IUUC-Aor-009972 Aspergillus oryzae 36.19 6.00e-16 75.10
IUUC-Ame-011674 Astyanax mexicanus 47.54 3.00e-15 72.80
IUUC-Bgr-012162 Blumeria graminis 57.38 1.00e-16 77.40
IUUC-Bta-012508 Bos taurus 47.54 3.00e-15 73.20
IUUC-Bci-013643 Botrytis cinerea 52.11 6.00e-18 81.60
IUUC-Bdi-014874 Brachypodium distachyon 29.56 2.00e-15 73.20
IUUC-Bol-015132 Brassica oleracea 35.62 6.00e-19 85.10
IUUC-Bra-017540 Brassica rapa 44.00 4.00e-11 59.30
IUUC-Cel-018111 Caenorhabditis elegans 44.26 2.00e-14 70.10
IUUC-Cja-019846 Callithrix jacchus 35.48 2.00e-20 93.60
IUUC-Cfa-020429 Canis familiaris 47.54 2.00e-15 73.20
IUUC-Cpo-021659 Cavia porcellus 33.73 1.00e-20 93.60
IUUC-Cre-022679 Chlamydomonas reinhardtii 40.98 1.00e-13 67.00
IUUC-Csa-023260 Chlorocebus sabaeus 37.28 3.00e-20 92.40
IUUC-Cho-024869 Choloepus hoffmanni 62.86 6.00e-08 48.50
IUUC-Cin-025166 Ciona intestinalis 34.71 3.00e-19 86.30
IUUC-Csv-026284 Ciona savignyi 46.15 2.00e-12 62.40
IUUC-Cgl-026520 Colletotrichum gloeosporioides 55.88 1.00e-17 80.50
IUUC-Cne-026920 Cryptococcus neoformans 46.67 8.00e-14 68.20
IUUC-Cme-027301 Cyanidioschyzon merolae 43.86 1.00e-11 60.80
IUUC-Dre-027840 Danio rerio 36.09 5.00e-21 92.00
IUUC-Dno-029367 Dasypus novemcinctus 31.02 9.00e-19 88.20
IUUC-Dor-030962 Dipodomys ordii 47.54 2.00e-15 73.20
IUUC-Dme-032061 Drosophila melanogaster 45.76 3.00e-14 69.70
IUUC-Ete-033075 Echinops telfairi 37.50 3.00e-18 85.10
IUUC-Eca-034049 Equus caballus 45.90 2.00e-14 70.50
IUUC-Eeu-034673 Erinaceus europaeus 47.54 3.00e-15 73.20
IUUC-Fca-035429 Felis catus 36.09 2.00e-21 96.70
IUUC-Fal-037006 Ficedula albicollis 47.54 3.00e-15 73.20
IUUC-Fox-037704 Fusarium oxysporum 50.00 4.00e-18 82.40
IUUC-Fso-038247 Fusarium solani 52.05 2.00e-17 80.10
IUUC-Gmo-039002 Gadus morhua 44.26 7.00e-14 68.60
IUUC-Ggr-039888 Gaeumannomyces graminis 54.41 2.00e-16 76.30
IUUC-Gga-040237 Gallus gallus 47.54 3.00e-15 72.80
IUUC-Gac-041800 Gasterosteus aculeatus 47.54 7.00e-15 73.20
IUUC-Gma-043275 Glycine max 40.98 2.00e-13 67.00
IUUC-Ggo-045163 Gorilla gorilla 34.32 9.00e-24 101.00
IUUC-Hsa-045795 Homo sapiens 47.54 2.00e-14 74.30
IUUC-Hvu-047376 Hordeum vulgare 31.65 1.00e-17 80.90
IUUC-Itr-048152 Ictidomys tridecemlineatus 47.54 3.00e-15 73.20
IUUC-Kpa-049166 Komagataella pastoris 44.74 4.00e-29 119.00
IUUC-Lch-050076 Latimeria chalumnae 47.54 3.00e-15 73.20
IUUC-Lpe-051258 Leersia perrieri 32.08 1.00e-16 77.80
IUUC-Loc-052292 Lepisosteus oculatus 47.54 3.00e-15 72.80
IUUC-Lma-053293 Leptosphaeria maculans 49.25 2.00e-16 76.60
IUUC-Laf-054393 Loxodonta africana 44.26 9.00e-15 71.20
IUUC-Mcc-054632 Macaca mulatta 47.54 2.00e-14 73.90
IUUC-Meu-056242 Macropus eugenii 47.54 3.00e-15 72.80
IUUC-Mor-057099 Magnaporthe oryzae 55.88 1.00e-16 77.40
IUUC-Mpo-057543 Magnaporthe poae 52.38 2.00e-12 63.20
IUUC-Mtr-058769 Medicago truncatula 33.96 2.00e-15 73.20
IUUC-Mla-059166 Melampsora laricipopulina 33.33 1.00e-19 87.00
IUUC-Mga-059406 Meleagris gallopavo 47.54 4.00e-15 72.80
IUUC-Mvi-060390 Microbotryum violaceum 32.74 2.00e-18 83.20
IUUC-Mmr-061475 Microcebus murinus 33.85 6.00e-21 94.70
IUUC-Mdo-062077 Monodelphis domestica 47.54 4.00e-15 74.70
IUUC-Mmu-063984 Mus musculus 47.54 1.00e-14 74.30
IUUC-Mac-065175 Musa acuminata 32.08 8.00e-19 84.70
IUUC-Mpu-066751 Mustela putorius furo 35.29 6.00e-21 95.10
IUUC-Mlu-068234 Myotis lucifugus 47.54 3.00e-15 73.20
IUUC-Nfi-068541 Neosartorya fischeri 49.15 3.00e-14 69.30
IUUC-Ncr-068830 Neurospora crassa 55.38 4.00e-18 82.40
IUUC-Nle-069126 Nomascus leucogenys 47.54 3.00e-15 72.80
IUUC-Opr-070742 Ochotona princeps 47.54 4.00e-15 72.80
IUUC-Ont-071828 Oreochromis niloticus 47.54 3.00e-15 73.20
IUUC-Oan-073462 Ornithorhynchus anatinus 47.54 1.00e-14 74.30
IUUC-Ocu-074890 Oryctolagus cuniculus 33.72 1.00e-19 90.90
IUUC-Oba-075995 Oryza barthii 32.08 4.00e-19 85.90
IUUC-Obr-076073 Oryza brachyantha 32.08 3.00e-19 86.30
IUUC-Ogl-077445 Oryza glaberrima 32.08 4.00e-19 85.90
IUUC-Ogu-078606 Oryza glumaepatula 32.08 4.00e-19 85.90
IUUC-Oin-079287 Oryza indica 32.08 4.00e-19 85.90
IUUC-Olo-080686 Oryza longistaminata 26.82 8.00e-14 68.20
IUUC-Ome-081567 Oryza meridionalis 29.19 3.00e-17 79.00
IUUC-Oni-082873 Oryza nivara 32.08 4.00e-19 85.90
IUUC-Opu-083488 Oryza punctata 29.56 1.00e-16 77.80
IUUC-Oru-084592 Oryza rufipogon 32.08 4.00e-19 85.90
IUUC-Osa-086102 Oryza sativa 32.08 4.00e-19 85.50
IUUC-Ola-087531 Oryzias latipes 47.54 4.00e-15 72.40
IUUC-Olu-087895 Ostreococcus lucimarinus 40.38 4.00e-11 58.20
IUUC-Oga-088239 Otolemur garnettii 47.54 3.00e-15 73.20
IUUC-Oar-090371 Ovis aries 36.09 3.00e-20 92.40
IUUC-Ptr-090481 Pan troglodytes 36.05 4.00e-18 85.50
IUUC-Pan-092210 Papio anubis 37.28 3.00e-20 92.80
IUUC-Psi-093588 Pelodiscus sinensis 47.54 3.00e-15 73.20
IUUC-Pma-094702 Petromyzon marinus 47.54 4.00e-15 72.80
IUUC-Pno-094927 Phaeosphaeria nodorum 47.76 5.00e-16 75.50
IUUC-Ppa-095389 Physcomitrella patens 41.38 2.00e-12 63.50
IUUC-Pfo-096744 Poecilia formosa 47.54 4.00e-15 72.80
IUUC-Pab-098044 Pongo abelii 47.54 3.00e-15 73.20
IUUC-Pop-099384 Populus trichocarpa 30.59 6.00e-20 88.20
IUUC-Pca-100355 Procavia capensis 30.37 6.00e-19 88.20
IUUC-Ppe-101786 Prunus persica 31.45 2.00e-19 86.30
IUUC-Pva-102494 Pteropus vampyrus 47.54 3.00e-15 73.20
IUUC-Pgr-103303 Puccinia graminis 48.81 2.00e-17 80.50
IUUC-Ptt-103748 Puccinia triticina 61.36 1.00e-12 64.30
IUUC-Pte-104368 Pyrenophora teres 47.76 4.00e-16 75.50
IUUC-Pyt-104542 Pyrenophora triticirepentis 47.76 2.00e-16 76.60
IUUC-Rno-105387 Rattus norvegicus 47.54 2.00e-14 74.30
IUUC-Sce-106371 Saccharomyces cerevisiae 34.41 4.00e-19 85.10
IUUC-Sha-107189 Sarcophilus harrisii 47.54 3.00e-15 73.20
IUUC-Sja-107942 Schizosaccharomyces japonicus 43.18 2.00e-14 69.70
IUUC-Spo-108121 Schizosaccharomyces pombe 39.39 6.00e-19 84.70
IUUC-Ssl-108595 Sclerotinia sclerotiorum 56.92 4.00e-18 82.40
IUUC-Smo-108783 Selaginella moellendorffii 40.38 3.00e-11 59.70
IUUC-Sit-110180 Setaria italica 31.45 5.00e-18 82.00
IUUC-Sly-110957 Solanum lycopersicum 30.19 3.00e-17 79.30
IUUC-Stu-112873 Solanum tuberosum 28.93 7.00e-16 74.70
IUUC-Sar-113668 Sorex araneus 62.86 5.00e-08 48.90
IUUC-Sbi-114328 Sorghum bicolor 30.82 2.00e-17 80.10
IUUC-Sre-115220 Sporisorium reilianum 40.86 4.00e-15 72.40
IUUC-Ssc-116119 Sus scrofa 47.54 3.00e-15 73.20
IUUC-Tgu-116528 Taeniopygia guttata 47.54 2.00e-15 73.20
IUUC-Tru-117538 Takifugu rubripes 47.54 2.00e-15 73.20
IUUC-Tsy-118855 Tarsius syrichta 62.86 1.00e-07 47.80
IUUC-Tni-120134 Tetraodon nigroviridis 47.54 4.00e-15 72.80
IUUC-Tca-121524 Theobroma cacao 32.08 2.00e-19 86.70
IUUC-Tre-121915 Trichoderma reesei 53.42 4.00e-17 79.30
IUUC-Tvi-122411 Trichoderma virens 55.38 5.00e-16 75.50
IUUC-Tae-124851 Triticum aestivum 31.65 2.00e-17 80.10
IUUC-Tur-126821 Triticum urartu 31.65 2.00e-17 79.70
IUUC-Tme-126875 Tuber melanosporum 50.82 2.00e-15 73.20
IUUC-Tbe-127759 Tupaia belangeri 44.23 6.00e-11 58.50
IUUC-Ttr-129124 Tursiops truncatus 34.62 1.00e-20 94.00
IUUC-Uma-129551 Ustilago maydis 41.46 5.00e-16 75.10
IUUC-Vda-129992 Verticillium dahliae 55.22 9.00e-19 84.30
IUUC-Vpa-130096 Vicugna pacos 45.90 3.00e-13 66.20
IUUC-Vvi-130940 Vitis vinifera 33.33 6.00e-16 75.10
IUUC-Xtr-132454 Xenopus tropicalis 47.54 4.00e-15 72.80
IUUC-Xma-133842 Xiphophorus maculatus 47.54 2.00e-15 73.60
IUUC-Zma-135748 Zea mays 42.00 1.00e-11 60.80
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved