iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011816

Ensembl Protein ID

ENSAMXP00000021233.1

UniProt Accession

W5LN21; W5LN21_ASTMX

Genbank Protein ID

ENSAMXP00000021233

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

APWO01078497

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000020619.1	ENSAMXT00000021233.1	ENSAMXP00000021233.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.10e-17	61.8	86	142

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           ++++lydy+a ++d+Lt++kG++ ++i  ++++++W+++ + ++gk+G +P+n+v+ ++
   Q: 86   LFIALYDYDARTEDDLTFQKGEKFHII--NNTEGDWWEARSLDTGKSGYIPSNYVAPVD 142
           5789***********************..8999**********************9987 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MGCACCKLRK TSKPSAVSIA NSCGAEDRVQ VDNRYIPDPV PNSGAGLIPN YNDFPNTGPG 60
AFSSSSFPSN VSQPRSTAIT GGGVTLFIAL YDYDARTEDD LTFQKGEKFH IINNTEGDWW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTTATTGCA CACTCTTTGT TTTGCACACT TCTGTCTGTG TGTCCCGGGC AGGGAGGGCA 60
GTGATGGGGA GAGAGTGGGG GGGGGGGGGG GGGGGGGGGT AGCTGGTGCA GTGTGCGCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0048246--P:macrophage chemotaxis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004483	Anolis carolinensis	80.51	0.00e+00	885.00
IUUC-Bdi-014324	Brachypodium distachyon	36.14	2.00e-23	104.00
IUUC-Cel-018594	Caenorhabditis elegans	55.92	5.00e-147	514.00
IUUC-Dre-028216	Danio rerio	88.91	0.00e+00	979.00
IUUC-Fal-036786	Ficedula albicollis	84.34	0.00e+00	866.00
IUUC-Gga-040762	Gallus gallus	79.12	0.00e+00	874.00
IUUC-Gac-041918	Gasterosteus aculeatus	84.50	0.00e+00	910.00
IUUC-Loc-052620	Lepisosteus oculatus	83.15	0.00e+00	914.00
IUUC-Oba-075994	Oryza barthii	34.16	5.00e-21	96.70
IUUC-Ogl-077331	Oryza glaberrima	34.65	7.00e-24	105.00
IUUC-Ogu-078962	Oryza glumaepatula	34.65	8.00e-24	105.00
IUUC-Oin-079172	Oryza indica	34.65	7.00e-24	105.00
IUUC-Olo-080286	Oryza longistaminata	34.65	7.00e-24	105.00
IUUC-Ome-081400	Oryza meridionalis	34.65	7.00e-24	105.00
IUUC-Oni-082734	Oryza nivara	34.65	2.00e-23	104.00
IUUC-Oru-084741	Oryza rufipogon	34.65	7.00e-24	105.00
IUUC-Osa-085779	Oryza sativa	34.62	6.00e-24	106.00
IUUC-Ola-086657	Oryzias latipes	86.94	0.00e+00	915.00
IUUC-Tru-117916	Takifugu rubripes	92.31	0.00e+00	884.00
IUUC-Tni-120886	Tetraodon nigroviridis	82.66	0.00e+00	922.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence