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Basic Information Integrated Annotations

Tag Content
iUUCD ID IUUC-Mmu-064010
Ensembl Protein ID ENSMUSP00000084794.3
UniProt Accession Q8C9B9; A2AJ47; A2AJ48; B2RS46; Q05C59; Q3ZTP5; Q3ZTP6; Q4V9W1; Q6ZQD7; Q80V34; Q8BMD0; Q8BRG2; Q8CHR5; Q9WV00; DIDO1_MOUSE
Genbank Protein ID CAB48401.1; AAR84049.1; AAR84050.1; BAC97927.1; BAC28053.1; BAC31270.1; BAC32141.1; CAM27684.1; CAM27685.1; CAM27686.1; CAM27687.1; AAH29110.1; AAH44755.1; AAH96662.1; AAI38713.1; AAI38714.1
Protein Name Death-inducer obliterator 1; Death-associated transcription factor 1
Genbank Nucleotide ID AJ238332; AY425951; AY425952; AK129117; AK032843; AK042474; AK044919; AL732560; AL732560; AL732560; AL732560; BC029110; BC044755; BC096662; BC138712; BC138713
Gene Name Dido1; Datf1; Dio1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000038914.15 ENSMUST00000087517.9 ENSMUSP00000084794.3
ENSMUSG00000038914.15 ENSMUST00000103057.7 ENSMUSP00000099346.1
ENSMUSG00000038914.15 ENSMUST00000103055.7 ENSMUSP00000099344.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemicroRNATRANSFACRepTar
RAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
Mentha
Protein 3D Structure
PDBMMDB
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
Phospho.ELMUniProtPHOSIDAmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 2.60e-08 35.0 267 317
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClkls...veeelpnsekwiCpkCr 52
    +C +C++++++ + +++C++C+ewfH +C+++s +n e++iCp+C+
   Q: 267 YC-ICRQPHNN-RFMICCDRCEEWFHGDCVGISearGRLLERNGEDYICPNCT 317
    89.*******5.58999999*************7654444567777******6 PP
   

Organism Mus musculus
Functional Description
(View)

Functional Description



     Required for early embryonic stem cell development (By similarity). Putative transcription factor, weakly pro-apoptotic when overexpressed.
Required for early embryonic stem cell development (By similarity). Putative transcription factor, weakly pro-apoptotic when overexpressed.
Protein Sequence
(Fasta)
MDDKGHLSNE EAPKAIKPTS KEFRKTWGFR RTTIAKREGA GDTEVDPSEQ QPQQHNLSLR 60
RSGRQPKRTE RVEEFLTTVR RRGKKNVPVS LEDSSEPTSS TVTDVETASE GSVESSSEIR 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Mmu-064010|E3,PHD|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CGCTTTTGCG CAAGATGGCT GCTGCGGGGG CATTCGCGTA CTGAGTGCTA GCGCGGGGAT 60
GGAGACGTGT AGACTGAGTT CGAAACGAAG GTCCCAGCTC TTTTCTTGTT TTTGTGTGTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Mmu-064010|E3,PHD|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0025--Alternative splicing
KW-0053--Apoptosis
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0903--Direct protein sequencing
KW-0479--Metal-binding
KW-0488--Methylation
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR033082--DIDO1
IPR012921--SPOC_C
IPR003618--TFIIS_cen_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51321--TFIIS_CENTRAL
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00628--PHD
PF07744--SPOC
PF07500--TFIIS_M

SMART

SM00249--PHD
SM00510--TFS2M

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0005819--C:spindle
GO:0003723--F:RNA binding
GO:0008270--F:zinc ion binding
GO:0097190--P:apoptotic signaling pathway
GO:0006351--P:transcription, DNA-templated

KEGG mmu:23856
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001202 Ailuropoda melanoleuca 71.56 0.00e+00 1702.00
IUUC-Apl-003835 Anas platyrhynchos 64.90 5.00e-166 578.00
IUUC-Aca-004562 Anolis carolinensis 52.32 0.00e+00 1677.00
IUUC-Ani-009326 Aspergillus nidulans 53.57 5.00e-14 73.20
IUUC-Bta-013233 Bos taurus 66.78 0.00e+00 2128.00
IUUC-Cja-019811 Callithrix jacchus 72.23 0.00e+00 649.00
IUUC-Cfa-021034 Canis familiaris 75.40 0.00e+00 1563.00
IUUC-Cpo-021803 Cavia porcellus 73.93 0.00e+00 2602.00
IUUC-Csa-023686 Chlorocebus sabaeus 71.07 0.00e+00 2331.00
IUUC-Csv-026099 Ciona savignyi 65.45 2.00e-23 102.00
IUUC-Cgl-026411 Colletotrichum gloeosporioides 55.56 5.00e-15 75.50
IUUC-Dre-028475 Danio rerio 45.15 2.00e-60 226.00
IUUC-Dno-029513 Dasypus novemcinctus 74.29 0.00e+00 1492.00
IUUC-Dor-030833 Dipodomys ordii 70.63 0.00e+00 2105.00
IUUC-Dse-031262 Dothistroma septosporum 55.77 8.00e-15 75.90
IUUC-Ete-032750 Echinops telfairi 61.01 0.00e+00 818.00
IUUC-Fal-036812 Ficedula albicollis 55.21 0.00e+00 1768.00
IUUC-Fox-037812 Fusarium oxysporum 47.06 1.00e-12 67.80
IUUC-Fso-038446 Fusarium solani 50.00 1.00e-13 70.90
IUUC-Ggr-039960 Gaeumannomyces graminis 50.00 2.00e-13 70.90
IUUC-Gga-040620 Gallus gallus 64.04 1.00e-162 566.00
IUUC-Gac-041527 Gasterosteus aculeatus 42.71 0.00e+00 763.00
IUUC-Ggo-044747 Gorilla gorilla 71.71 0.00e+00 2424.00
IUUC-Hsa-046225 Homo sapiens 71.85 0.00e+00 2407.00
IUUC-Itr-048422 Ictidomys tridecemlineatus 77.60 0.00e+00 2790.00
IUUC-Kpa-049206 Komagataella pastoris 27.97 2.00e-08 54.30
IUUC-Lch-050039 Latimeria chalumnae 55.90 0.00e+00 773.00
IUUC-Laf-053940 Loxodonta africana 67.49 0.00e+00 2220.00
IUUC-Mcc-055809 Macaca mulatta 71.21 0.00e+00 2358.00
IUUC-Mor-057044 Magnaporthe oryzae 50.00 5.00e-13 69.30
IUUC-Mpo-057588 Magnaporthe poae 50.00 2.00e-13 70.50
IUUC-Mga-060017 Meleagris gallopavo 57.95 0.00e+00 1826.00
IUUC-Mmr-061055 Microcebus murinus 72.54 0.00e+00 2369.00
IUUC-Mdo-062683 Monodelphis domestica 68.20 0.00e+00 1465.00
IUUC-Mac-064704 Musa acuminata 57.58 7.00e-10 58.50
IUUC-Mpu-066844 Mustela putorius furo 73.25 0.00e+00 1555.00
IUUC-Mlu-067160 Myotis lucifugus 68.03 0.00e+00 2335.00
IUUC-Nle-070068 Nomascus leucogenys 71.53 0.00e+00 2429.00
IUUC-Ont-072366 Oreochromis niloticus 42.40 2.00e-148 521.00
IUUC-Oan-072746 Ornithorhynchus anatinus 67.48 0.00e+00 1251.00
IUUC-Ocu-074336 Oryctolagus cuniculus 67.98 0.00e+00 1509.00
IUUC-Ogl-076925 Oryza glaberrima 31.68 3.00e-11 62.40
IUUC-Ola-086406 Oryzias latipes 40.38 3.00e-138 487.00
IUUC-Oga-088506 Otolemur garnettii 71.30 0.00e+00 2518.00
IUUC-Ptr-091448 Pan troglodytes 71.38 0.00e+00 2347.00
IUUC-Pan-092481 Papio anubis 76.57 0.00e+00 1595.00
IUUC-Psi-092995 Pelodiscus sinensis 57.21 0.00e+00 1550.00
IUUC-Pab-098673 Pongo abelii 71.76 0.00e+00 2398.00
IUUC-Rno-105243 Rattus norvegicus 91.78 0.00e+00 3400.00
IUUC-Sha-107260 Sarcophilus harrisii 70.38 0.00e+00 1542.00
IUUC-Sja-107904 Schizosaccharomyces japonicus 33.13 1.00e-15 78.60
IUUC-Stu-112199 Solanum tuberosum 38.89 4.00e-12 65.90
IUUC-Tgu-117059 Taeniopygia guttata 54.65 0.00e+00 1763.00
IUUC-Tru-117650 Takifugu rubripes 47.19 2.00e-129 457.00
IUUC-Tre-122185 Trichoderma reesei 60.78 1.00e-15 77.40
IUUC-Tvi-122269 Trichoderma virens 58.82 5.00e-15 75.50
IUUC-Ttr-129315 Tursiops truncatus 68.16 0.00e+00 1538.00
IUUC-Vpa-130265 Vicugna pacos 76.54 4.00e-99 356.00
IUUC-Xma-133754 Xiphophorus maculatus 42.77 3.00e-137 484.00
Created Date 25-Jun-2017

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