iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033897

UUCD1 version

UUC-EqC-00242

Ensembl Protein ID

ENSECAP00000013364.1

UniProt Accession

F6TT77; F6TT77_HORSE

Protein Name

Uncharacterized protein

Gene Name

TBL1Y

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000015324.1	ENSECAT00000016550.1	ENSECAP00000013364.1
ENSECAG00000015324.1	ENSECAT00000016645.1	ENSECAP00000013450.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.20e-54	177.5	453	491
UBD/Beta-Prp	2.80e-64	217.3	330	525

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           H+++v+++af +d ++l+sGs D+ +++W++ +g l++s
   Q: 453  HQEPVYSVAFsPDgKYLASGSFDKCVHIWNTQSGSLVHS 491
           9**********999******************9999875 PP

UBD/Beta-Prp

   S: 21   dksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..... 104
           +++ +a+ s+d +i v ++     +++++gh++ev+a+k++p+g +l+++s+D+t+k+w++++ +cvh l++h+++++++++sp     
   Q: 330  NNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDTCVHDLQAHSKEIYTIKWSPtgpat 418
           55667777777777777777777788888888888888888888888888888888888888888888888888888887777766655 PP
   S: 105  ....sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfd 189
               s+  l+s+s d+t+r+wd+e g c++ tl++h++ v +v+++pdg++l+sGs D++v +W+ ++g+l++  +g  t+ +  + ++
   Q: 419  snpnSNIMLASASFDSTVRLWDVERGVCIH-TLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGSLVHSYRG--TGGIFEVCWN 504
           555333567888888888888888888888.8888888888888888888888888888888888888888888877..8888888888 PP
   S: 190  sngkelvsgsldgtvklwdlq 210
             g  + + + dg+v + dl+
   Q: 505  ARGDKVGASASDGSVCVLDLR 525
           888888888888888777765 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MSITSDEVNF LVYRYLQESG FSHSAFTFGI ESHISQSNIN GTLVPPAALI SILQKGLQYV 60
EAEISINEDG TVFDGRPIES LSLIDAVMPD VVQTRQQAFR EKLAQQQASA AAAAAAAATT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTTCCCCGT TTCTCACCAG GCGGCTCCTG GCAGACGCTT TGTGATTTCT CTGATTGGAT 60
GCTGGGGAGC CCACTGTTCC AAAGGTCCAC ACATGAAGTC ACCATAAAGG TAAGCGCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08513--LisH
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00667--LisH
SM00320--WD40

Gene Ontology

GO:0000118--C:histone deacetylase complex
GO:0005667--C:transcription factor complex
GO:0003682--F:chromatin binding
GO:0003714--F:transcription corepressor activity
GO:0044212--F:transcription regulatory region DNA binding
GO:0045444--P:fat cell differentiation
GO:0016575--P:histone deacetylation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0043627--P:response to estrogen
GO:0048545--P:response to steroid hormone

KEGG

ecb:100054115

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001450	Ailuropoda melanoleuca	93.73	0.00e+00	999.00
IUUC-Atr-002514	Amborella trichopoda	64.01	2.00e-142	498.00
IUUC-Apl-003232	Anas platyrhynchos	97.15	0.00e+00	1003.00
IUUC-Aca-005035	Anolis carolinensis	95.07	0.00e+00	1005.00
IUUC-Aly-005622	Arabidopsis lyrata	55.58	5.00e-119	421.00
IUUC-Ath-007137	Arabidopsis thaliana	58.95	3.00e-120	425.00
IUUC-Ago-007869	Ashbya gossypii	27.68	8.00e-33	134.00
IUUC-Ame-011601	Astyanax mexicanus	83.27	0.00e+00	867.00
IUUC-Bta-013202	Bos taurus	97.35	0.00e+00	1016.00
IUUC-Bdi-014315	Brachypodium distachyon	60.92	3.00e-134	471.00
IUUC-Bol-016277	Brassica oleracea	56.70	2.00e-125	442.00
IUUC-Bra-016944	Brassica rapa	57.07	6.00e-125	441.00
IUUC-Cja-019281	Callithrix jacchus	92.59	0.00e+00	985.00
IUUC-Cfa-020929	Canis familiaris	98.10	0.00e+00	1014.00
IUUC-Cpo-022080	Cavia porcellus	83.52	0.00e+00	853.00
IUUC-Cre-022979	Chlamydomonas reinhardtii	61.43	1.00e-131	462.00
IUUC-Csa-023943	Chlorocebus sabaeus	94.11	0.00e+00	982.00
IUUC-Cin-025704	Ciona intestinalis	72.91	0.00e+00	798.00
IUUC-Csv-026257	Ciona savignyi	70.07	0.00e+00	761.00
IUUC-Cne-026946	Cryptococcus neoformans	38.01	1.00e-30	128.00
IUUC-Cme-027258	Cyanidioschyzon merolae	39.08	1.00e-104	373.00
IUUC-Dre-028075	Danio rerio	85.17	0.00e+00	877.00
IUUC-Dno-028926	Dasypus novemcinctus	95.45	0.00e+00	995.00
IUUC-Dor-030732	Dipodomys ordii	90.93	0.00e+00	686.00
IUUC-Dme-031939	Drosophila melanogaster	81.74	3.00e-176	611.00
IUUC-Ete-032822	Echinops telfairi	84.41	0.00e+00	846.00
IUUC-Eeu-034952	Erinaceus europaeus	79.16	0.00e+00	759.00
IUUC-Fca-036462	Felis catus	96.77	0.00e+00	1012.00
IUUC-Fal-037388	Ficedula albicollis	97.15	0.00e+00	1014.00
IUUC-Gmo-038870	Gadus morhua	83.08	0.00e+00	885.00
IUUC-Gga-040671	Gallus gallus	97.15	0.00e+00	1014.00
IUUC-Gac-041851	Gasterosteus aculeatus	89.92	0.00e+00	937.00
IUUC-Gma-044208	Glycine max	47.73	2.00e-152	532.00
IUUC-Ggo-045373	Gorilla gorilla	94.69	0.00e+00	993.00
IUUC-Hsa-045841	Homo sapiens	95.06	0.00e+00	998.00
IUUC-Itr-048236	Ictidomys tridecemlineatus	99.73	0.00e+00	783.00
IUUC-Kpa-049338	Komagataella pastoris	28.00	1.00e-31	130.00
IUUC-Lch-050535	Latimeria chalumnae	91.63	0.00e+00	981.00
IUUC-Lpe-051084	Leersia perrieri	61.81	4.00e-134	471.00
IUUC-Loc-052030	Lepisosteus oculatus	88.43	0.00e+00	904.00
IUUC-Laf-054071	Loxodonta africana	96.79	0.00e+00	1013.00
IUUC-Mcc-055233	Macaca mulatta	92.10	0.00e+00	967.00
IUUC-Meu-056563	Macropus eugenii	91.18	4.00e-129	454.00
IUUC-Mtr-058624	Medicago truncatula	59.89	2.00e-126	445.00
IUUC-Mga-059895	Meleagris gallopavo	96.96	0.00e+00	1014.00
IUUC-Mvi-060557	Microbotryum violaceum	37.04	4.00e-70	259.00
IUUC-Mmr-061286	Microcebus murinus	97.55	0.00e+00	1020.00
IUUC-Mdo-062078	Monodelphis domestica	88.05	0.00e+00	890.00
IUUC-Mmu-063447	Mus musculus	97.53	0.00e+00	1010.00
IUUC-Mac-065508	Musa acuminata	61.05	2.00e-91	329.00
IUUC-Mpu-066741	Mustela putorius furo	87.86	0.00e+00	885.00
IUUC-Mlu-068152	Myotis lucifugus	88.24	0.00e+00	884.00
IUUC-Nle-069151	Nomascus leucogenys	93.92	0.00e+00	989.00
IUUC-Opr-070277	Ochotona princeps	78.27	0.00e+00	746.00
IUUC-Ont-072252	Oreochromis niloticus	89.92	0.00e+00	961.00
IUUC-Oan-073562	Ornithorhynchus anatinus	97.34	0.00e+00	1016.00
IUUC-Ocu-074280	Oryctolagus cuniculus	85.93	0.00e+00	891.00
IUUC-Oba-075618	Oryza barthii	48.47	1.00e-143	503.00
IUUC-Obr-076718	Oryza brachyantha	61.39	3.00e-135	475.00
IUUC-Ogl-077302	Oryza glaberrima	50.63	1.00e-155	542.00
IUUC-Ogu-078718	Oryza glumaepatula	50.63	2.00e-155	542.00
IUUC-Oin-079515	Oryza indica	44.34	4.00e-94	339.00
IUUC-Olo-080427	Oryza longistaminata	62.18	1.00e-129	456.00
IUUC-Ome-081696	Oryza meridionalis	49.55	2.00e-150	525.00
IUUC-Oni-082137	Oryza nivara	50.63	2.00e-155	542.00
IUUC-Opu-083505	Oryza punctata	48.11	6.00e-143	500.00
IUUC-Oru-085276	Oryza rufipogon	50.63	6.00e-156	543.00
IUUC-Osa-085791	Oryza sativa	50.63	2.00e-155	542.00
IUUC-Ola-087365	Oryzias latipes	84.79	0.00e+00	898.00
IUUC-Olu-087589	Ostreococcus lucimarinus	51.64	3.00e-155	541.00
IUUC-Oga-088357	Otolemur garnettii	84.25	0.00e+00	833.00
IUUC-Oar-089506	Ovis aries	95.25	0.00e+00	1011.00
IUUC-Ptr-090793	Pan troglodytes	92.40	0.00e+00	957.00
IUUC-Pan-091909	Papio anubis	93.76	0.00e+00	992.00
IUUC-Psi-093358	Pelodiscus sinensis	91.22	0.00e+00	962.00
IUUC-Pma-094105	Petromyzon marinus	62.95	9.00e-100	356.00
IUUC-Ppa-095868	Physcomitrella patens	66.02	3.00e-139	488.00
IUUC-Pfo-097214	Poecilia formosa	88.59	0.00e+00	929.00
IUUC-Pab-098317	Pongo abelii	94.77	0.00e+00	976.00
IUUC-Pop-098989	Populus trichocarpa	57.64	7.00e-129	453.00
IUUC-Pca-100256	Procavia capensis	87.93	0.00e+00	874.00
IUUC-Ppe-101572	Prunus persica	63.69	9.00e-128	450.00
IUUC-Pva-102616	Pteropus vampyrus	87.86	0.00e+00	878.00
IUUC-Rno-105857	Rattus norvegicus	97.53	0.00e+00	1010.00
IUUC-Sce-106132	Saccharomyces cerevisiae	24.48	9.00e-40	157.00
IUUC-Sha-107326	Sarcophilus harrisii	95.25	0.00e+00	1021.00
IUUC-Smo-109301	Selaginella moellendorffii	63.22	3.00e-141	494.00
IUUC-Sit-110710	Setaria italica	61.89	6.00e-140	491.00
IUUC-Sly-111042	Solanum lycopersicum	50.09	2.00e-149	522.00
IUUC-Stu-112786	Solanum tuberosum	48.31	3.00e-141	494.00
IUUC-Sar-112971	Sorex araneus	81.64	0.00e+00	812.00
IUUC-Sbi-114420	Sorghum bicolor	61.39	6.00e-140	490.00
IUUC-Sre-115175	Sporisorium reilianum	40.07	2.00e-56	214.00
IUUC-Ssc-115646	Sus scrofa	98.68	0.00e+00	1024.00
IUUC-Tgu-116898	Taeniopygia guttata	97.34	0.00e+00	1005.00
IUUC-Tru-117862	Takifugu rubripes	89.92	0.00e+00	948.00
IUUC-Tsy-119424	Tarsius syrichta	73.08	0.00e+00	674.00
IUUC-Tni-119656	Tetraodon nigroviridis	90.68	0.00e+00	948.00
IUUC-Tca-121739	Theobroma cacao	54.04	4.00e-124	438.00
IUUC-Tae-125368	Triticum aestivum	50.36	3.00e-155	541.00
IUUC-Tur-126856	Triticum urartu	42.65	3.00e-75	275.00
IUUC-Tme-127126	Tuber melanosporum	37.28	4.00e-56	212.00
IUUC-Tbe-127665	Tupaia belangeri	74.90	0.00e+00	762.00
IUUC-Ttr-128826	Tursiops truncatus	97.52	0.00e+00	927.00
IUUC-Uma-129469	Ustilago maydis	43.53	2.00e-58	220.00
IUUC-Vpa-130768	Vicugna pacos	88.12	0.00e+00	872.00
IUUC-Vvi-131193	Vitis vinifera	56.89	4.00e-129	455.00
IUUC-Xtr-132842	Xenopus tropicalis	86.15	0.00e+00	853.00
IUUC-Xma-133591	Xiphophorus maculatus	88.40	0.00e+00	927.00
IUUC-Yli-134648	Yarrowia lipolytica	29.62	8.00e-42	165.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence