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Tag Content
UUCD2 ID IUUC-Oga-088264
UUCD1 version UUC-OtG-00293
Ensembl Protein ID ENSOGAP00000005878.2
UniProt Accession H0WUH2; H0WUH2_OTOGA
Genbank Protein ID ENSOGAP00000005878
Protein Name Ribosome biogenesis protein WDR12; WD repeat-containing protein 12
Genbank Nucleotide ID AAQR03032627
Gene Name WDR12
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOGAG00000006573.2 ENSOGAT00000006577.2 ENSOGAP00000005878.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.40e-44 148.1 341 376
UBD/Beta-Prp 3.30e-47 161.1 246 412
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWDlrtgv 34
           Ht++vt++++  +    l+sGs D+ +k+WD+r+++
   Q: 341  HTGWVTSVKWspTHeQQLISGSLDNIVKLWDTRSCK 376
           **********9533678**************99876 PP
   

   UBD/Beta-Prp
   S: 83   tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl..ktg 169
           t+++++tl+gh++ + s+ +s   + + s+s+d tirvwd+e+g+  + tl+g++ v nc++++p ++ l+sGs+Dr +rlWd   k g
   Q: 246  TRTPMVTLSGHKEAISSVLWSD-AEEICSASWDHTIRVWDVESGSLKS-TLTGNK-VFNCISYSPLCKRLASGSTDRHIRLWDPrtKDG 331
           678899***************9.99**********************9.***987.99**************************54456 PP
   S: 170  kllrtl.tgghtdsvyslsfdsng.kelvsgsldgtvklwdlq.tgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW 249
           +l+    t+ ht+ v+s++++++  ++l+sgsld+ vklwd +  +  ++ l +h+d v+sv+ + ++ +l+sg++D+ ++ +
   Q: 332  SLVSLSlTS-HTGWVTSVKWSPTHeQQLISGSLDNIVKLWDTRsCKAPLYDLAAHEDKVLSVDWT-DSGLLLSGGADNKLYSY 412
           666644366.************9889*****************54566****************9.***********998765 PP
   
Organism Otolemur garnettii
Functional Description
(View)

Functional Description


     Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
 Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
Protein Sequence
(Fasta)
MAQLQTRFYT DNKKYAIDDV PFSIPAASEI ADLSNIINKL LKDKNDFHKH VEFDFLIKGQ 60
FLRMPLLKHM ELENISSEEV VELEYVEKYT APQPEQCMFH DDWISSIKGA EEWILTGSYD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Oga-088264|E3,WD_repeat;UBD,Beta-Prp|Otolemur garnettii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TGCGGACCAC CCGCCATGGC TCAGCTTCAA ACACGCTTCT ATACTGATAA TAAGAAGTAA 60
GTAAGCGTCT CGCCTTCTAT CCCTTCCCTA GGGTTTTTTT TTCCCCTCTT GAGACAGAGT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Oga-088264|E3,WD_repeat;UBD,Beta-Prp|Otolemur garnettii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR012972--NLE
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR028599--WDR12/Ytm1
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF08154--NLE
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0005654--C:nucleoplasm
GO:0070545--C:PeBoW complex
GO:0030687--C:preribosome, large subunit precursor
GO:0043021--F:ribonucleoprotein complex binding
GO:0008283--P:cell proliferation
GO:0000466--P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000463--P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0007219--P:Notch signaling pathway
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000532 Aegilops tauschii 32.38 2.00e-55 209.00
IUUC-Aml-001997 Ailuropoda melanoleuca 95.37 0.00e+00 743.00
IUUC-Atr-002544 Amborella trichopoda 32.38 2.00e-55 209.00
IUUC-Apl-003981 Anas platyrhynchos 85.37 0.00e+00 640.00
IUUC-Aca-004370 Anolis carolinensis 83.06 0.00e+00 715.00
IUUC-Aly-006455 Arabidopsis lyrata 33.99 2.00e-56 213.00
IUUC-Ath-006669 Arabidopsis thaliana 33.42 8.00e-53 201.00
IUUC-Ago-007864 Ashbya gossypii 29.09 6.00e-37 148.00
IUUC-Acl-008177 Aspergillus clavatus 29.23 5.00e-35 142.00
IUUC-Afl-008617 Aspergillus flavus 27.67 8.00e-34 138.00
IUUC-Afu-008752 Aspergillus fumigatus 27.56 1.00e-32 134.00
IUUC-Ani-009136 Aspergillus nidulans 29.31 3.00e-34 139.00
IUUC-Ang-009701 Aspergillus niger 28.13 3.00e-32 132.00
IUUC-Aor-009884 Aspergillus oryzae 28.16 6.00e-34 138.00
IUUC-Ame-011432 Astyanax mexicanus 75.65 0.00e+00 662.00
IUUC-Bgr-012218 Blumeria graminis 28.37 1.00e-31 130.00
IUUC-Bta-012829 Bos taurus 95.27 0.00e+00 769.00
IUUC-Bci-013953 Botrytis cinerea 28.54 5.00e-34 138.00
IUUC-Bdi-014351 Brachypodium distachyon 35.07 4.00e-54 205.00
IUUC-Bol-016190 Brassica oleracea 33.77 1.00e-52 200.00
IUUC-Bra-017876 Brassica rapa 33.25 6.00e-55 207.00
IUUC-Cel-018569 Caenorhabditis elegans 32.11 3.00e-47 182.00
IUUC-Cja-019468 Callithrix jacchus 95.51 0.00e+00 758.00
IUUC-Cfa-020471 Canis familiaris 94.80 0.00e+00 762.00
IUUC-Cpo-022260 Cavia porcellus 94.56 0.00e+00 750.00
IUUC-Cre-022614 Chlamydomonas reinhardtii 30.71 4.00e-40 158.00
IUUC-Csa-023989 Chlorocebus sabaeus 95.98 0.00e+00 761.00
IUUC-Cho-024426 Choloepus hoffmanni 91.75 7.00e-159 553.00
IUUC-Cin-025789 Ciona intestinalis 44.15 3.00e-97 348.00
IUUC-Cne-027063 Cryptococcus neoformans 24.53 4.00e-22 99.40
IUUC-Dre-027907 Danio rerio 75.65 0.00e+00 671.00
IUUC-Dno-029225 Dasypus novemcinctus 94.80 0.00e+00 768.00
IUUC-Dor-031082 Dipodomys ordii 77.54 1.00e-167 582.00
IUUC-Dse-031308 Dothistroma septosporum 28.05 4.00e-37 149.00
IUUC-Dme-032189 Drosophila melanogaster 41.50 8.00e-93 333.00
IUUC-Ete-032247 Echinops telfairi 87.23 0.00e+00 701.00
IUUC-Eca-034285 Equus caballus 94.80 0.00e+00 766.00
IUUC-Eeu-035322 Erinaceus europaeus 83.42 0.00e+00 637.00
IUUC-Fca-036114 Felis catus 94.56 0.00e+00 764.00
IUUC-Fal-036891 Ficedula albicollis 85.59 3.00e-174 603.00
IUUC-Fox-037965 Fusarium oxysporum 25.37 1.00e-33 137.00
IUUC-Fso-038244 Fusarium solani 25.79 4.00e-33 135.00
IUUC-Gmo-039040 Gadus morhua 74.94 0.00e+00 667.00
IUUC-Gga-040610 Gallus gallus 82.51 0.00e+00 706.00
IUUC-Gac-042117 Gasterosteus aculeatus 73.52 0.00e+00 634.00
IUUC-Gma-043146 Glycine max 35.82 2.00e-63 236.00
IUUC-Ggo-045179 Gorilla gorilla 95.51 0.00e+00 753.00
IUUC-Hsa-046114 Homo sapiens 96.22 0.00e+00 758.00
IUUC-Hvu-047331 Hordeum vulgare 33.16 3.00e-51 195.00
IUUC-Itr-048275 Ictidomys tridecemlineatus 95.04 0.00e+00 767.00
IUUC-Kpa-049304 Komagataella pastoris 29.11 1.00e-41 163.00
IUUC-Lch-050655 Latimeria chalumnae 75.52 3.00e-147 514.00
IUUC-Lpe-051675 Leersia perrieri 34.84 6.00e-57 215.00
IUUC-Loc-052868 Lepisosteus oculatus 80.14 0.00e+00 679.00
IUUC-Lma-053258 Leptosphaeria maculans 26.78 5.00e-33 137.00
IUUC-Laf-053993 Loxodonta africana 94.56 0.00e+00 769.00
IUUC-Mcc-055128 Macaca mulatta 78.49 7.00e-172 596.00
IUUC-Meu-056501 Macropus eugenii 78.28 2.00e-161 561.00
IUUC-Mor-057114 Magnaporthe oryzae 25.11 7.00e-25 108.00
IUUC-Mtr-058367 Medicago truncatula 35.73 4.00e-59 221.00
IUUC-Mla-059107 Melampsora laricipopulina 26.57 3.00e-28 119.00
IUUC-Mga-059745 Meleagris gallopavo 80.47 0.00e+00 680.00
IUUC-Mvi-060362 Microbotryum violaceum 29.93 7.00e-33 135.00
IUUC-Mdo-062257 Monodelphis domestica 85.20 0.00e+00 719.00
IUUC-Mmu-063546 Mus musculus 92.67 0.00e+00 754.00
IUUC-Mac-065540 Musa acuminata 33.49 3.00e-54 206.00
IUUC-Mpu-066284 Mustela putorius furo 95.98 0.00e+00 773.00
IUUC-Mlu-067241 Myotis lucifugus 94.80 0.00e+00 767.00
IUUC-Nfi-068260 Neosartorya fischeri 27.32 5.00e-33 135.00
IUUC-Ncr-068719 Neurospora crassa 25.79 2.00e-25 110.00
IUUC-Nle-068981 Nomascus leucogenys 95.98 0.00e+00 756.00
IUUC-Opr-071218 Ochotona princeps 87.44 0.00e+00 687.00
IUUC-Ont-071646 Oreochromis niloticus 76.14 0.00e+00 661.00
IUUC-Oan-073453 Ornithorhynchus anatinus 87.71 0.00e+00 748.00
IUUC-Ocu-074008 Oryctolagus cuniculus 95.51 0.00e+00 772.00
IUUC-Oba-075712 Oryza barthii 30.53 3.00e-40 159.00
IUUC-Obr-076721 Oryza brachyantha 34.36 2.00e-56 213.00
IUUC-Ogl-077229 Oryza glaberrima 34.37 7.00e-56 211.00
IUUC-Ogu-078977 Oryza glumaepatula 30.53 1.00e-40 160.00
IUUC-Oin-079683 Oryza indica 34.37 4.00e-56 211.00
IUUC-Olo-080291 Oryza longistaminata 30.30 5.00e-27 114.00
IUUC-Ome-081834 Oryza meridionalis 34.61 7.00e-57 214.00
IUUC-Oni-082507 Oryza nivara 33.25 4.00e-52 198.00
IUUC-Opu-083396 Oryza punctata 34.61 9.00e-57 214.00
IUUC-Oru-085220 Oryza rufipogon 33.81 7.00e-52 197.00
IUUC-Osa-085767 Oryza sativa 34.37 4.00e-56 211.00
IUUC-Ola-087420 Oryzias latipes 76.36 0.00e+00 676.00
IUUC-Olu-087740 Ostreococcus lucimarinus 28.54 2.00e-38 152.00
IUUC-Oar-089335 Ovis aries 95.27 0.00e+00 768.00
IUUC-Ptr-091320 Pan troglodytes 96.22 0.00e+00 758.00
IUUC-Pan-092833 Papio anubis 95.51 0.00e+00 756.00
IUUC-Psi-093504 Pelodiscus sinensis 85.34 0.00e+00 707.00
IUUC-Pma-094189 Petromyzon marinus 67.45 2.00e-170 592.00
IUUC-Pno-094929 Phaeosphaeria nodorum 26.17 1.00e-34 140.00
IUUC-Ppa-095429 Physcomitrella patens 34.92 2.00e-64 239.00
IUUC-Pfo-096337 Poecilia formosa 74.47 0.00e+00 666.00
IUUC-Pab-097571 Pongo abelii 96.45 0.00e+00 758.00
IUUC-Pop-099977 Populus trichocarpa 34.62 6.00e-62 231.00
IUUC-Pca-100394 Procavia capensis 89.24 0.00e+00 689.00
IUUC-Ppe-101848 Prunus persica 35.47 4.00e-59 221.00
IUUC-Pva-102921 Pteropus vampyrus 94.33 3.00e-119 421.00
IUUC-Pgr-103637 Puccinia graminis 27.74 1.00e-32 134.00
IUUC-Ptt-103781 Puccinia triticina 27.19 6.00e-33 135.00
IUUC-Pte-104135 Pyrenophora teres 25.83 3.00e-33 137.00
IUUC-Pyt-104609 Pyrenophora triticirepentis 25.93 7.00e-32 131.00
IUUC-Rno-105114 Rattus norvegicus 92.20 0.00e+00 754.00
IUUC-Sce-106401 Saccharomyces cerevisiae 28.95 3.00e-38 152.00
IUUC-Sha-107122 Sarcophilus harrisii 85.16 0.00e+00 687.00
IUUC-Sja-107766 Schizosaccharomyces japonicus 31.78 1.00e-48 187.00
IUUC-Spo-108134 Schizosaccharomyces pombe 29.36 3.00e-39 155.00
IUUC-Ssl-108398 Sclerotinia sclerotiorum 28.50 2.00e-35 143.00
IUUC-Smo-108720 Selaginella moellendorffii 33.10 4.00e-55 208.00
IUUC-Sit-110311 Setaria italica 35.81 9.00e-55 207.00
IUUC-Sly-111178 Solanum lycopersicum 33.33 6.00e-56 211.00
IUUC-Stu-112778 Solanum tuberosum 34.61 1.00e-59 223.00
IUUC-Sar-113596 Sorex araneus 77.54 2.00e-169 588.00
IUUC-Sbi-114193 Sorghum bicolor 34.96 1.00e-55 210.00
IUUC-Sre-115002 Sporisorium reilianum 23.71 4.00e-11 62.80
IUUC-Ssc-116066 Sus scrofa 95.04 0.00e+00 765.00
IUUC-Tgu-117048 Taeniopygia guttata 84.31 0.00e+00 637.00
IUUC-Tsy-119573 Tarsius syrichta 62.92 5.00e-138 483.00
IUUC-Tni-119820 Tetraodon nigroviridis 75.77 0.00e+00 666.00
IUUC-Tca-121605 Theobroma cacao 34.86 2.00e-59 223.00
IUUC-Tre-121947 Trichoderma reesei 26.50 7.00e-33 134.00
IUUC-Tvi-122481 Trichoderma virens 26.71 5.00e-34 138.00
IUUC-Tae-125861 Triticum aestivum 32.62 9.00e-56 210.00
IUUC-Tur-126586 Triticum urartu 33.16 2.00e-53 202.00
IUUC-Tme-126900 Tuber melanosporum 32.39 1.00e-49 190.00
IUUC-Tbe-127736 Tupaia belangeri 73.12 4.00e-147 514.00
IUUC-Ttr-129041 Tursiops truncatus 83.92 0.00e+00 679.00
IUUC-Uma-129628 Ustilago maydis 24.69 1.00e-12 67.80
IUUC-Vpa-130260 Vicugna pacos 95.51 0.00e+00 773.00
IUUC-Vvi-131009 Vitis vinifera 34.29 1.00e-58 220.00
IUUC-Xtr-132083 Xenopus tropicalis 80.38 0.00e+00 690.00
IUUC-Xma-133094 Xiphophorus maculatus 73.76 0.00e+00 659.00
IUUC-Yli-134531 Yarrowia lipolytica 22.73 2.00e-18 87.00
IUUC-Zma-135509 Zea mays 33.10 1.00e-55 210.00
Created Date 25-Jun-2017

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