iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074526

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02059942

Gene Name

MUL1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000000628.2	ENSOCUT00000000626.2	ENSOCUP00000000543.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	92.61	0.00e+00	639.00	IUUC-Hsa-046597

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MESGGKPSLG QFILLGTSSV VTAVLYSVYR QKAQVSRELK GAKKIHLGED LKSILSEAPG 60
KCVPYAVIEG AVRSVKETLN SQFVENCKGV IQRLTLQEHK MVWNRTTHLW NDCSKIIHQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGAGCG GGGGGAAGCC CTCGCTGGGC CAGTTCATCC TCCTGGGCAC CAGCTCGGTC 60
GTCACCGCCG TGCTGTACTC GGTGTACCGG CAGAAGGCCC AGGTCTCCCG AGAGCTCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR022170--GIDE
IPR001841--Znf_RING

PROSITE

PS50089--ZF_RING_2

Pfam

PF12483--GIDE

Gene Ontology

GO:0030424--C:axon
GO:0031307--C:integral component of mitochondrial outer membrane
GO:0043025--C:neuronal cell body
GO:0005777--C:peroxisome
GO:0004871--F:signal transducer activity
GO:0019789--F:SUMO transferase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007257--P:activation of JUN kinase activity
GO:0071360--P:cellular response to exogenous dsRNA
GO:0000266--P:mitochondrial fission
GO:0051646--P:mitochondrion localization
GO:0030308--P:negative regulation of cell growth
GO:0071650--P:negative regulation of chemokine (C-C motif) ligand 5 production
GO:0050689--P:negative regulation of defense response to virus by host
GO:0010637--P:negative regulation of mitochondrial fusion
GO:0051898--P:negative regulation of protein kinase B signaling
GO:0060339--P:negative regulation of type I interferon-mediated signaling pathway
GO:1903861--P:positive regulation of dendrite extension
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0090141--P:positive regulation of mitochondrial fission
GO:1904925--P:positive regulation of mitophagy in response to mitochondrial depolarization
GO:0033235--P:positive regulation of protein sumoylation
GO:0031648--P:protein destabilization
GO:0050821--P:protein stabilization
GO:0051881--P:regulation of mitochondrial membrane potential
GO:1901028--P:regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

KEGG

ocu:100350921

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002287	Ailuropoda melanoleuca	91.19	0.00e+00	645.00
IUUC-Atr-002698	Amborella trichopoda	24.53	1.00e-08	54.30
IUUC-Aca-005039	Anolis carolinensis	39.42	2.00e-66	245.00
IUUC-Aly-006181	Arabidopsis lyrata	27.79	2.00e-21	96.70
IUUC-Ath-007438	Arabidopsis thaliana	28.08	2.00e-22	99.80
IUUC-Ame-010671	Astyanax mexicanus	64.20	4.00e-135	473.00
IUUC-Bta-012407	Bos taurus	81.87	1.00e-168	585.00
IUUC-Bdi-014735	Brachypodium distachyon	24.56	3.00e-17	82.40
IUUC-Bol-015493	Brassica oleracea	26.36	7.00e-23	101.00
IUUC-Bra-016933	Brassica rapa	27.36	4.00e-20	92.00
IUUC-Cja-019709	Callithrix jacchus	92.52	0.00e+00	633.00
IUUC-Cfa-020818	Canis familiaris	91.76	0.00e+00	662.00
IUUC-Cpo-022490	Cavia porcellus	91.76	0.00e+00	635.00
IUUC-Csa-023259	Chlorocebus sabaeus	92.61	0.00e+00	689.00
IUUC-Cho-024730	Choloepus hoffmanni	92.90	0.00e+00	684.00
IUUC-Cin-025301	Ciona intestinalis	30.63	3.00e-45	175.00
IUUC-Dre-028644	Danio rerio	64.49	4.00e-137	480.00
IUUC-Dno-028925	Dasypus novemcinctus	90.91	0.00e+00	677.00
IUUC-Dor-030692	Dipodomys ordii	93.18	0.00e+00	650.00
IUUC-Dme-031761	Drosophila melanogaster	30.95	4.00e-33	135.00
IUUC-Ete-032329	Echinops telfairi	80.97	1.00e-153	535.00
IUUC-Eca-034008	Equus caballus	89.20	0.00e+00	665.00
IUUC-Eeu-034895	Erinaceus europaeus	77.24	1.00e-121	429.00
IUUC-Fca-036104	Felis catus	91.19	0.00e+00	659.00
IUUC-Fal-036900	Ficedula albicollis	74.34	9.00e-141	493.00
IUUC-Gmo-039049	Gadus morhua	58.81	5.00e-106	377.00
IUUC-Gga-040254	Gallus gallus	71.31	5.00e-146	510.00
IUUC-Gac-042277	Gasterosteus aculeatus	60.51	4.00e-135	473.00
IUUC-Gma-043979	Glycine max	26.28	6.00e-19	87.80
IUUC-Ggo-045509	Gorilla gorilla	92.61	0.00e+00	689.00
IUUC-Hsa-046597	Homo sapiens	92.61	0.00e+00	689.00
IUUC-Hvu-047335	Hordeum vulgare	26.64	4.00e-20	91.30
IUUC-Itr-048691	Ictidomys tridecemlineatus	93.47	0.00e+00	654.00
IUUC-Lch-050344	Latimeria chalumnae	67.90	8.00e-146	509.00
IUUC-Loc-052376	Lepisosteus oculatus	65.91	2.00e-148	518.00
IUUC-Laf-054414	Loxodonta africana	92.33	0.00e+00	682.00
IUUC-Mcc-054604	Macaca mulatta	92.33	0.00e+00	687.00
IUUC-Meu-056087	Macropus eugenii	84.66	5.00e-173	600.00
IUUC-Mtr-057779	Medicago truncatula	27.03	8.00e-20	90.90
IUUC-Mga-060188	Meleagris gallopavo	73.40	8.00e-145	506.00
IUUC-Mmr-060704	Microcebus murinus	93.47	0.00e+00	689.00
IUUC-Mdo-062842	Monodelphis domestica	84.38	1.00e-165	575.00
IUUC-Mmu-064324	Mus musculus	90.62	0.00e+00	626.00
IUUC-Mpu-065940	Mustela putorius furo	88.92	4.00e-180	623.00
IUUC-Mlu-067028	Myotis lucifugus	91.19	0.00e+00	682.00
IUUC-Nle-069254	Nomascus leucogenys	85.88	0.00e+00	635.00
IUUC-Opr-070827	Ochotona princeps	89.77	0.00e+00	659.00
IUUC-Ont-072008	Oreochromis niloticus	61.93	3.00e-139	488.00
IUUC-Oan-072935	Ornithorhynchus anatinus	80.97	2.00e-171	594.00
IUUC-Obr-076592	Oryza brachyantha	27.11	6.00e-23	101.00
IUUC-Ogl-077732	Oryza glaberrima	27.11	1.00e-22	100.00
IUUC-Oin-080188	Oryza indica	27.11	1.00e-22	100.00
IUUC-Ola-087288	Oryzias latipes	58.81	4.00e-128	450.00
IUUC-Oga-088402	Otolemur garnettii	92.05	0.00e+00	686.00
IUUC-Oar-089851	Ovis aries	93.83	4.00e-90	323.00
IUUC-Ptr-091226	Pan troglodytes	92.33	0.00e+00	687.00
IUUC-Pan-092575	Papio anubis	92.05	0.00e+00	686.00
IUUC-Psi-094062	Pelodiscus sinensis	75.85	6.00e-166	576.00
IUUC-Pma-094501	Petromyzon marinus	37.64	8.00e-45	174.00
IUUC-Ppa-095285	Physcomitrella patens	24.84	9.00e-15	74.30
IUUC-Pfo-096146	Poecilia formosa	58.24	3.00e-123	434.00
IUUC-Pab-098524	Pongo abelii	92.33	0.00e+00	688.00
IUUC-Pop-099864	Populus trichocarpa	28.15	5.00e-20	91.70
IUUC-Pca-100314	Procavia capensis	91.48	0.00e+00	672.00
IUUC-Ppe-101663	Prunus persica	26.06	3.00e-18	85.90
IUUC-Pva-102947	Pteropus vampyrus	91.48	0.00e+00	679.00
IUUC-Rno-105024	Rattus norvegicus	90.34	0.00e+00	635.00
IUUC-Sha-107500	Sarcophilus harrisii	68.25	5.00e-124	436.00
IUUC-Smo-109194	Selaginella moellendorffii	27.46	7.00e-20	91.30
IUUC-Sit-109922	Setaria italica	27.11	2.00e-21	96.70
IUUC-Sly-111826	Solanum lycopersicum	26.95	5.00e-21	95.10
IUUC-Stu-112907	Solanum tuberosum	26.57	6.00e-20	91.30
IUUC-Sar-113522	Sorex araneus	88.78	2.00e-167	581.00
IUUC-Sbi-114536	Sorghum bicolor	27.49	2.00e-24	106.00
IUUC-Ssc-115445	Sus scrofa	92.61	0.00e+00	640.00
IUUC-Tgu-116551	Taeniopygia guttata	72.44	3.00e-136	478.00
IUUC-Tru-118407	Takifugu rubripes	57.95	2.00e-116	411.00
IUUC-Tsy-118794	Tarsius syrichta	90.91	0.00e+00	670.00
IUUC-Tni-120128	Tetraodon nigroviridis	66.53	9.00e-96	342.00
IUUC-Tca-121508	Theobroma cacao	26.80	5.00e-21	95.10
IUUC-Tae-125185	Triticum aestivum	26.39	2.00e-22	99.80
IUUC-Tur-126470	Triticum urartu	26.10	2.00e-22	99.40
IUUC-Tbe-127432	Tupaia belangeri	91.76	0.00e+00	633.00
IUUC-Ttr-128573	Tursiops truncatus	89.77	0.00e+00	647.00
IUUC-Vpa-130583	Vicugna pacos	90.71	1.00e-174	605.00
IUUC-Vvi-131710	Vitis vinifera	27.31	1.00e-18	87.40
IUUC-Xtr-132009	Xenopus tropicalis	63.28	2.00e-138	484.00
IUUC-Xma-134121	Xiphophorus maculatus	58.36	3.00e-128	451.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence