iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mac-065520

Ensembl Protein ID

GSMUA_Achr2P07570_001

UniProt Accession

M0S5Z8; M0S5Z8_MUSAM

Protein Name

Eukaryotic translation initiation factor 3 subunit I

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GSMUA_Achr2G07570_001	GSMUA_Achr2T07570_001	GSMUA_Achr2P07570_001

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.20e-25	87.6	45	83
UBD/Beta-Prp	1.20e-54	186.4	4	245

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH++ v+c++   d  +l++Gs D ++k+W++ tg +l 
   Q: 45   GHNGAVWCCDVsRDsMRLITGSADQSVKLWNVQTGAQLY 83
           8***********77799*****************98875 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgheds 96
           h+ ++t +k+ ++++ll++  +d+  +vw +++g  l ++ gh+++v++++ s+d+  l+tgs D+ +k+w+++tg ++++++  ++ 
   Q: 4    HERPLTFLKYNREGDLLFSCAKDHNPTVWFADNGERLGTYRGHNGAVWCCDVSRDSMRLITGSADQSVKLWNVQTGAQLYSFN-FDSP 90
           45566666666666666666666666666666666666666666666666666666666666666666666666666666666.6666 PP
   S: 97   vlslsfspsgdklvsGshdrtirvwdletgqclee..........................tlsghdgvvncvvvhpdgnllvsGslD 158
           ++s++fs  gdkl++ + d                                          t +g +g +n + + p ++ ++s++ D
   Q: 91   ARSVDFSV-GDKLAVITTD---------------PfmglpstiqvkriardpneqssesvlTIKGPQGRINRAIWGPLNKTIISAGED 162
           66666666.5555555555...............04444444444444445666666668899999********************** PP
   S: 159  rtvrlWdlktgkllrtl...tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsg 240
            +vr+Wd +tg+ll++    t gh++ v+sls + +g ++++gsld++ klwd +t + ++t+   + +v+  + sp  +++v g
   Q: 163  AVVRVWDTETGQLLKESdkeT-GHQKTVTSLSKSADGSHFLTGSLDKSAKLWDARTLTLIKTYVTER-PVNACAISPLLDHVVIG 245
           *****************9955.5***********************************999998654.55555555555555555 PP

Organism

Musa acuminata

Functional Description
(View)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Protein Sequence
(Fasta)

MKGHERPLTF LKYNREGDLL FSCAKDHNPT VWFADNGERL GTYRGHNGAV WCCDVSRDSM 60
RLITGSADQS VKLWNVQTGA QLYSFNFDSP ARSVDFSVGD KLAVITTDPF MGLPSTIQVK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGGGCC ATGAAAGGCC ATTGACGTTC CTCAAGTACA ACCGGGAGGG GGATCTGCTC 60
TTCTCCTGCG CCAAGGATCA CAACCCCACC GTCTGGTTCG CCGACAATGG CGAGAGGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027525--eIF3i
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016282--C:eukaryotic 43S preinitiation complex
GO:0033290--C:eukaryotic 48S preinitiation complex
GO:0005852--C:eukaryotic translation initiation factor 3 complex
GO:0003743--F:translation initiation factor activity
GO:0001731--P:formation of translation preinitiation complex
GO:0006446--P:regulation of translational initiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000115	Aegilops tauschii	88.33	1.00e-58	219.00
IUUC-Aml-001321	Ailuropoda melanoleuca	48.14	1.00e-87	315.00
IUUC-Atr-002468	Amborella trichopoda	86.14	7.00e-104	369.00
IUUC-Apl-003841	Anas platyrhynchos	48.14	1.00e-88	318.00
IUUC-Aca-005123	Anolis carolinensis	46.73	1.00e-88	319.00
IUUC-Aly-005473	Arabidopsis lyrata	75.54	8.00e-150	522.00
IUUC-Ath-007094	Arabidopsis thaliana	74.92	2.00e-149	521.00
IUUC-Ago-008000	Ashbya gossypii	45.15	2.00e-74	272.00
IUUC-Acl-008098	Aspergillus clavatus	45.37	2.00e-77	281.00
IUUC-Afl-008494	Aspergillus flavus	45.91	1.00e-80	292.00
IUUC-Afu-009080	Aspergillus fumigatus	44.75	2.00e-77	281.00
IUUC-Ani-009230	Aspergillus nidulans	47.50	8.00e-81	293.00
IUUC-Aor-010114	Aspergillus oryzae	45.91	1.00e-80	292.00
IUUC-Ate-010285	Aspergillus terreus	46.88	4.00e-80	290.00
IUUC-Ame-011534	Astyanax mexicanus	47.53	4.00e-90	323.00
IUUC-Bgr-012121	Blumeria graminis	44.03	1.00e-75	275.00
IUUC-Bta-013143	Bos taurus	48.14	1.00e-87	315.00
IUUC-Bci-013950	Botrytis cinerea	46.23	8.00e-82	296.00
IUUC-Bdi-015019	Brachypodium distachyon	80.06	7.00e-158	549.00
IUUC-Bol-015709	Brassica oleracea	77.54	4.00e-154	537.00
IUUC-Bra-017760	Brassica rapa	77.54	3.00e-155	541.00
IUUC-Cel-018226	Caenorhabditis elegans	41.38	6.00e-70	256.00
IUUC-Cja-019741	Callithrix jacchus	47.83	2.00e-87	315.00
IUUC-Cfa-021204	Canis familiaris	47.83	2.00e-87	315.00
IUUC-Cpo-021661	Cavia porcellus	47.83	2.00e-87	315.00
IUUC-Cre-022952	Chlamydomonas reinhardtii	50.78	5.00e-100	356.00
IUUC-Csa-024038	Chlorocebus sabaeus	47.83	2.00e-87	315.00
IUUC-Cin-025597	Ciona intestinalis	46.42	6.00e-84	303.00
IUUC-Cgl-026583	Colletotrichum gloeosporioides	44.69	1.00e-76	278.00
IUUC-Cne-026838	Cryptococcus neoformans	43.52	2.00e-80	291.00
IUUC-Cme-027304	Cyanidioschyzon merolae	52.35	9.00e-88	316.00
IUUC-Dre-028567	Danio rerio	47.20	3.00e-90	324.00
IUUC-Dno-029171	Dasypus novemcinctus	48.14	6.00e-87	314.00
IUUC-Dor-030257	Dipodomys ordii	37.04	4.00e-26	111.00
IUUC-Dse-031191	Dothistroma septosporum	45.68	1.00e-77	282.00
IUUC-Dme-031879	Drosophila melanogaster	49.06	2.00e-90	325.00
IUUC-Ete-032336	Echinops telfairi	41.01	2.00e-44	171.00
IUUC-Eca-033259	Equus caballus	47.83	3.00e-87	314.00
IUUC-Eeu-035153	Erinaceus europaeus	43.80	4.00e-27	114.00
IUUC-Fca-036489	Felis catus	47.83	3.00e-87	314.00
IUUC-Fal-037485	Ficedula albicollis	47.83	2.00e-88	318.00
IUUC-Fox-037860	Fusarium oxysporum	45.28	1.00e-77	282.00
IUUC-Fso-038188	Fusarium solani	45.60	5.00e-77	280.00
IUUC-Gmo-039311	Gadus morhua	47.83	5.00e-89	320.00
IUUC-Ggr-040045	Gaeumannomyces graminis	45.60	4.00e-78	283.00
IUUC-Gga-040645	Gallus gallus	46.97	1.00e-86	312.00
IUUC-Gac-042086	Gasterosteus aculeatus	47.52	9.00e-88	315.00
IUUC-Gma-043246	Glycine max	88.16	1.00e-173	600.00
IUUC-Ggo-045578	Gorilla gorilla	47.83	2.00e-87	315.00
IUUC-Hsa-046734	Homo sapiens	47.83	2.00e-87	315.00
IUUC-Hvu-047553	Hordeum vulgare	80.69	2.00e-158	551.00
IUUC-Itr-048467	Ictidomys tridecemlineatus	47.83	3.00e-87	314.00
IUUC-Kpa-049325	Komagataella pastoris	46.08	3.00e-79	287.00
IUUC-Lch-049620	Latimeria chalumnae	48.82	4.00e-80	290.00
IUUC-Lpe-051338	Leersia perrieri	81.37	5.00e-151	526.00
IUUC-Loc-052094	Lepisosteus oculatus	43.34	6.00e-76	276.00
IUUC-Lma-053047	Leptosphaeria maculans	47.48	3.00e-82	297.00
IUUC-Laf-053801	Loxodonta africana	48.44	2.00e-87	315.00
IUUC-Mcc-055498	Macaca mulatta	42.55	5.00e-69	253.00
IUUC-Meu-056729	Macropus eugenii	44.27	6.00e-78	283.00
IUUC-Mor-057025	Magnaporthe oryzae	45.45	2.00e-76	278.00
IUUC-Mpo-057511	Magnaporthe poae	46.39	9.00e-78	283.00
IUUC-Mtr-058051	Medicago truncatula	86.60	9.00e-172	595.00
IUUC-Mla-059061	Melampsora laricipopulina	44.55	3.00e-77	281.00
IUUC-Mga-059229	Meleagris gallopavo	47.53	3.00e-86	310.00
IUUC-Mvi-060399	Microbotryum violaceum	43.81	9.00e-78	283.00
IUUC-Mmr-060764	Microcebus murinus	48.14	5.00e-88	317.00
IUUC-Mdo-062088	Monodelphis domestica	47.68	1.00e-87	315.00
IUUC-Mmu-064304	Mus musculus	47.83	1.00e-87	315.00
IUUC-Mpu-066340	Mustela putorius furo	47.83	3.00e-87	314.00
IUUC-Mlu-067111	Myotis lucifugus	48.14	9.00e-88	316.00
IUUC-Nfi-068478	Neosartorya fischeri	44.75	4.00e-78	284.00
IUUC-Ncr-068820	Neurospora crassa	46.86	2.00e-78	285.00
IUUC-Nle-069903	Nomascus leucogenys	47.83	1.00e-87	315.00
IUUC-Opr-070221	Ochotona princeps	46.89	1.00e-84	305.00
IUUC-Ont-071765	Oreochromis niloticus	48.45	8.00e-92	329.00
IUUC-Oan-073660	Ornithorhynchus anatinus	46.58	1.00e-77	282.00
IUUC-Ocu-074039	Oryctolagus cuniculus	47.83	2.00e-87	315.00
IUUC-Oba-075395	Oryza barthii	75.08	4.00e-142	496.00
IUUC-Obr-076334	Oryza brachyantha	78.82	6.00e-151	525.00
IUUC-Ogl-077751	Oryza glaberrima	82.87	3.00e-162	563.00
IUUC-Ogu-078207	Oryza glumaepatula	82.19	2.00e-160	557.00
IUUC-Oin-079878	Oryza indica	82.55	1.00e-161	561.00
IUUC-Olo-080677	Oryza longistaminata	70.93	7.00e-153	532.00
IUUC-Ome-081228	Oryza meridionalis	60.43	6.00e-79	286.00
IUUC-Oni-082411	Oryza nivara	72.59	2.00e-135	474.00
IUUC-Opu-083136	Oryza punctata	82.55	8.00e-162	561.00
IUUC-Oru-084916	Oryza rufipogon	80.91	4.00e-160	556.00
IUUC-Osa-085776	Oryza sativa	82.87	3.00e-162	563.00
IUUC-Ola-087053	Oryzias latipes	48.45	1.00e-89	322.00
IUUC-Olu-087602	Ostreococcus lucimarinus	60.00	1.00e-119	422.00
IUUC-Oga-088154	Otolemur garnettii	47.52	2.00e-86	311.00
IUUC-Oar-089915	Ovis aries	48.14	1.00e-87	315.00
IUUC-Ptr-091124	Pan troglodytes	38.51	1.00e-59	222.00
IUUC-Pan-092035	Papio anubis	47.83	2.00e-87	315.00
IUUC-Psi-094096	Pelodiscus sinensis	46.12	2.00e-55	207.00
IUUC-Pno-094988	Phaeosphaeria nodorum	44.97	3.00e-72	264.00
IUUC-Ppa-095949	Physcomitrella patens	78.19	3.00e-154	537.00
IUUC-Pfo-096101	Poecilia formosa	47.20	4.00e-90	323.00
IUUC-Pab-097726	Pongo abelii	47.83	2.00e-87	315.00
IUUC-Pop-099617	Populus trichocarpa	85.98	5.00e-170	589.00
IUUC-Pca-101014	Procavia capensis	48.14	8.00e-88	316.00
IUUC-Ppe-101320	Prunus persica	84.74	2.00e-168	584.00
IUUC-Pva-102789	Pteropus vampyrus	44.10	6.00e-75	273.00
IUUC-Pgr-103479	Puccinia graminis	44.55	7.00e-78	283.00
IUUC-Ptt-103981	Puccinia triticina	44.24	2.00e-78	285.00
IUUC-Pte-104278	Pyrenophora teres	46.23	3.00e-79	288.00
IUUC-Pyt-104492	Pyrenophora triticirepentis	46.23	3.00e-79	288.00
IUUC-Rno-105867	Rattus norvegicus	43.47	1.00e-69	256.00
IUUC-Sce-106251	Saccharomyces cerevisiae	41.46	4.00e-73	267.00
IUUC-Sha-107039	Sarcophilus harrisii	47.68	1.00e-87	315.00
IUUC-Sja-107758	Schizosaccharomyces japonicus	45.65	1.00e-80	292.00
IUUC-Spo-108314	Schizosaccharomyces pombe	45.17	2.00e-83	301.00
IUUC-Ssl-108478	Sclerotinia sclerotiorum	45.91	1.00e-81	295.00
IUUC-Smo-108728	Selaginella moellendorffii	76.25	6.00e-151	525.00
IUUC-Sit-110801	Setaria italica	80.06	4.00e-158	549.00
IUUC-Sly-111326	Solanum lycopersicum	82.55	2.00e-164	570.00
IUUC-Stu-112458	Solanum tuberosum	83.80	2.00e-165	573.00
IUUC-Sbi-114063	Sorghum bicolor	78.82	3.00e-156	543.00
IUUC-Sre-115096	Sporisorium reilianum	44.31	6.00e-74	270.00
IUUC-Ssc-116080	Sus scrofa	48.14	1.00e-87	315.00
IUUC-Tgu-116988	Taeniopygia guttata	47.83	2.00e-88	318.00
IUUC-Tru-118766	Takifugu rubripes	47.52	1.00e-89	322.00
IUUC-Tni-120197	Tetraodon nigroviridis	47.83	5.00e-90	323.00
IUUC-Tca-121316	Theobroma cacao	85.67	2.00e-169	587.00
IUUC-Tre-122097	Trichoderma reesei	46.56	7.00e-79	286.00
IUUC-Tvi-122442	Trichoderma virens	45.94	6.00e-78	283.00
IUUC-Tae-125800	Triticum aestivum	80.69	3.00e-158	550.00
IUUC-Tur-126334	Triticum urartu	71.34	6.00e-133	466.00
IUUC-Tme-127038	Tuber melanosporum	46.54	7.00e-82	296.00
IUUC-Ttr-128659	Tursiops truncatus	45.34	2.00e-67	248.00
IUUC-Uma-129464	Ustilago maydis	43.37	3.00e-74	271.00
IUUC-Vda-129841	Verticillium dahliae	46.23	3.00e-77	281.00
IUUC-Vvi-131076	Vitis vinifera	87.23	2.00e-173	600.00
IUUC-Xtr-132395	Xenopus tropicalis	48.45	1.00e-88	319.00
IUUC-Xma-133383	Xiphophorus maculatus	47.20	8.00e-90	323.00
IUUC-Yli-134586	Yarrowia lipolytica	43.75	4.00e-70	257.00
IUUC-Zma-135904	Zea mays	80.06	2.00e-158	550.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence