iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-118735

Ensembl Protein ID

ENSTRUP00000041884.1

UniProt Accession

H2UY55; H2UY55_TAKRU

Protein Name

Non-specific serine/threonine protein kinase

Gene Name

PRKAA2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000016384.1	ENSTRUT00000042028.1	ENSTRUP00000041884.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	48.78	2.00e-126	449.00	IUUC-Ath-007014
UBD/Alpha-Helix/UBA	40.53	6.00e-108	385.00	IUUC-Spo-108202

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MAERQQQKHE GRVKIGHYIL GDTLGVGTFG KVKIGEHQLT GHKVAVKILN RQKIRSLDVV 60
GKIKREIQNL KLFRHPHIIK LYQVISTPTD FFMVMEYVSG GELFDYICKH GRVEDTEARR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGAGC GGCAACAACA GAAGCACGAA GGCAGGGTAA AGATCGGCCA TTACATCCTC 60
GGAGACACGC TCGGAGTGGG GACATTCGGG AAAGTGAAGA GTTAAGTCAC GCTTTTTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR032270--AMPK_C
IPR028375--KA1/Ssp2_C
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF16579--AdenylateSensor
PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0031588--C:nucleotide-activated protein kinase complex
GO:0005634--C:nucleus
GO:0004679--F:AMP-activated protein kinase activity
GO:0005524--F:ATP binding
GO:0035174--F:histone serine kinase activity
GO:0042149--P:cellular response to glucose starvation
GO:0035404--P:histone-serine phosphorylation
GO:0035556--P:intracellular signal transduction
GO:0032007--P:negative regulation of TOR signaling

KEGG

tru:101076074

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000713	Aegilops tauschii	47.47	6.00e-124	437.00
IUUC-Aml-001907	Ailuropoda melanoleuca	72.99	0.00e+00	768.00
IUUC-Atr-002770	Amborella trichopoda	49.39	1.00e-126	446.00
IUUC-Apl-003395	Anas platyrhynchos	86.29	0.00e+00	928.00
IUUC-Aca-004480	Anolis carolinensis	88.48	0.00e+00	950.00
IUUC-Aly-006289	Arabidopsis lyrata	48.67	2.00e-127	449.00
IUUC-Ath-007014	Arabidopsis thaliana	48.78	1.00e-127	449.00
IUUC-Ago-007957	Ashbya gossypii	42.83	8.00e-116	410.00
IUUC-Acl-008103	Aspergillus clavatus	61.87	1.00e-102	367.00
IUUC-Afl-008555	Aspergillus flavus	61.87	3.00e-103	369.00
IUUC-Afu-008949	Aspergillus fumigatus	61.87	1.00e-102	367.00
IUUC-Ani-009408	Aspergillus nidulans	61.45	4.00e-102	365.00
IUUC-Ang-009551	Aspergillus niger	61.87	3.00e-102	366.00
IUUC-Aor-010176	Aspergillus oryzae	61.87	3.00e-103	369.00
IUUC-Ate-010287	Aspergillus terreus	61.87	4.00e-102	365.00
IUUC-Ame-011019	Astyanax mexicanus	89.91	0.00e+00	1021.00
IUUC-Bgr-012045	Blumeria graminis	60.49	2.00e-102	366.00
IUUC-Bta-012786	Bos taurus	73.17	0.00e+00	769.00
IUUC-Bci-013774	Botrytis cinerea	60.84	1.00e-103	370.00
IUUC-Bdi-014319	Brachypodium distachyon	48.35	5.00e-125	441.00
IUUC-Bol-016242	Brassica oleracea	49.59	2.00e-131	462.00
IUUC-Bra-016750	Brassica rapa	49.59	1.00e-131	462.00
IUUC-Cel-018518	Caenorhabditis elegans	57.42	5.00e-180	624.00
IUUC-Cja-019386	Callithrix jacchus	84.41	0.00e+00	972.00
IUUC-Cfa-020177	Canis familiaris	72.30	0.00e+00	739.00
IUUC-Cpo-021805	Cavia porcellus	84.59	0.00e+00	974.00
IUUC-Cre-022915	Chlamydomonas reinhardtii	54.83	3.00e-95	341.00
IUUC-Csa-024267	Chlorocebus sabaeus	84.41	0.00e+00	969.00
IUUC-Cho-024859	Choloepus hoffmanni	70.74	0.00e+00	727.00
IUUC-Cin-025550	Ciona intestinalis	60.18	0.00e+00	666.00
IUUC-Csv-026139	Ciona savignyi	60.44	0.00e+00	674.00
IUUC-Cne-027044	Cryptococcus neoformans	51.03	9.00e-109	387.00
IUUC-Cme-027289	Cyanidioschyzon merolae	45.66	4.00e-112	398.00
IUUC-Dre-027749	Danio rerio	70.19	0.00e+00	772.00
IUUC-Dno-030006	Dasypus novemcinctus	72.99	0.00e+00	769.00
IUUC-Dor-030578	Dipodomys ordii	83.87	0.00e+00	969.00
IUUC-Dse-031507	Dothistroma septosporum	60.50	2.00e-102	367.00
IUUC-Dme-031704	Drosophila melanogaster	58.61	0.00e+00	649.00
IUUC-Ete-033055	Echinops telfairi	70.96	0.00e+00	780.00
IUUC-Eca-034016	Equus caballus	84.38	0.00e+00	917.00
IUUC-Fca-035754	Felis catus	71.55	0.00e+00	759.00
IUUC-Fal-037363	Ficedula albicollis	72.58	0.00e+00	756.00
IUUC-Fox-038073	Fusarium oxysporum	41.88	2.00e-103	370.00
IUUC-Fso-038236	Fusarium solani	41.60	7.00e-100	358.00
IUUC-Gmo-039633	Gadus morhua	68.90	0.00e+00	797.00
IUUC-Ggr-039987	Gaeumannomyces graminis	48.90	1.00e-101	363.00
IUUC-Gga-040546	Gallus gallus	86.54	0.00e+00	990.00
IUUC-Gac-041822	Gasterosteus aculeatus	91.76	0.00e+00	1005.00
IUUC-Gma-042712	Glycine max	48.37	5.00e-127	447.00
IUUC-Ggo-045303	Gorilla gorilla	84.59	0.00e+00	976.00
IUUC-Hsa-045746	Homo sapiens	84.59	0.00e+00	976.00
IUUC-Hvu-047406	Hordeum vulgare	47.40	9.00e-127	446.00
IUUC-Itr-048134	Ictidomys tridecemlineatus	84.41	0.00e+00	974.00
IUUC-Kpa-049190	Komagataella pastoris	44.77	2.00e-121	429.00
IUUC-Lch-049623	Latimeria chalumnae	71.89	0.00e+00	752.00
IUUC-Lpe-051392	Leersia perrieri	47.68	3.00e-126	445.00
IUUC-Loc-052928	Lepisosteus oculatus	89.59	0.00e+00	1015.00
IUUC-Lma-053054	Leptosphaeria maculans	56.41	7.00e-106	378.00
IUUC-Laf-053459	Loxodonta africana	84.59	0.00e+00	974.00
IUUC-Mcc-055862	Macaca mulatta	84.59	0.00e+00	976.00
IUUC-Mor-057170	Magnaporthe oryzae	58.10	2.00e-100	360.00
IUUC-Mpo-057302	Magnaporthe poae	49.45	1.00e-102	367.00
IUUC-Mtr-058309	Medicago truncatula	48.64	4.00e-126	444.00
IUUC-Mla-059058	Melampsora laricipopulina	41.37	2.00e-104	373.00
IUUC-Mga-059206	Meleagris gallopavo	86.26	0.00e+00	931.00
IUUC-Mvi-060337	Microbotryum violaceum	41.52	7.00e-106	378.00
IUUC-Mmr-061619	Microcebus murinus	84.59	0.00e+00	968.00
IUUC-Mdo-062160	Monodelphis domestica	85.66	0.00e+00	963.00
IUUC-Mmu-063406	Mus musculus	84.05	0.00e+00	967.00
IUUC-Mac-064518	Musa acuminata	46.41	9.00e-121	427.00
IUUC-Mpu-066326	Mustela putorius furo	84.38	0.00e+00	919.00
IUUC-Mlu-067968	Myotis lucifugus	84.02	0.00e+00	893.00
IUUC-Nfi-068493	Neosartorya fischeri	61.87	8.00e-103	368.00
IUUC-Ncr-068665	Neurospora crassa	60.63	1.00e-105	377.00
IUUC-Nle-070158	Nomascus leucogenys	84.41	0.00e+00	974.00
IUUC-Opr-070272	Ochotona princeps	70.45	0.00e+00	756.00
IUUC-Ont-071395	Oreochromis niloticus	96.59	0.00e+00	1083.00
IUUC-Oan-073322	Ornithorhynchus anatinus	67.13	0.00e+00	730.00
IUUC-Ocu-074188	Oryctolagus cuniculus	71.73	0.00e+00	761.00
IUUC-Oba-075436	Oryza barthii	47.36	5.00e-127	447.00
IUUC-Obr-076507	Oryza brachyantha	47.87	9.00e-127	446.00
IUUC-Ogl-077718	Oryza glaberrima	47.36	1.00e-125	442.00
IUUC-Ogu-078349	Oryza glumaepatula	47.70	8.00e-127	447.00
IUUC-Oin-079889	Oryza indica	47.66	2.00e-126	445.00
IUUC-Olo-080521	Oryza longistaminata	47.70	6.00e-127	447.00
IUUC-Ome-081630	Oryza meridionalis	47.49	1.00e-126	446.00
IUUC-Oni-082211	Oryza nivara	47.70	3.00e-127	448.00
IUUC-Opu-083617	Oryza punctata	47.40	2.00e-126	446.00
IUUC-Oru-084252	Oryza rufipogon	47.70	6.00e-127	447.00
IUUC-Osa-085548	Oryza sativa	47.70	6.00e-127	447.00
IUUC-Ola-087169	Oryzias latipes	94.43	0.00e+00	1060.00
IUUC-Olu-087861	Ostreococcus lucimarinus	48.96	7.00e-119	421.00
IUUC-Oga-088003	Otolemur garnettii	73.17	0.00e+00	770.00
IUUC-Oar-089933	Ovis aries	73.17	0.00e+00	769.00
IUUC-Ptr-090741	Pan troglodytes	84.59	0.00e+00	976.00
IUUC-Pan-092526	Papio anubis	73.17	0.00e+00	769.00
IUUC-Psi-094034	Pelodiscus sinensis	72.81	0.00e+00	753.00
IUUC-Pno-095030	Phaeosphaeria nodorum	60.71	1.00e-103	369.00
IUUC-Ppa-095615	Physcomitrella patens	50.91	5.00e-123	434.00
IUUC-Pfo-096295	Poecilia formosa	95.69	0.00e+00	1075.00
IUUC-Pab-098023	Pongo abelii	84.59	0.00e+00	976.00
IUUC-Pop-100042	Populus trichocarpa	48.88	1.00e-128	453.00
IUUC-Pca-101104	Procavia capensis	75.55	1.00e-167	583.00
IUUC-Ppe-101642	Prunus persica	47.46	4.00e-124	437.00
IUUC-Pva-102470	Pteropus vampyrus	84.23	0.00e+00	966.00
IUUC-Pgr-103406	Puccinia graminis	60.07	4.00e-91	329.00
IUUC-Ptt-103713	Puccinia triticina	50.85	2.00e-72	267.00
IUUC-Pte-104259	Pyrenophora teres	54.30	2.00e-106	380.00
IUUC-Pyt-104752	Pyrenophora triticirepentis	54.93	5.00e-107	382.00
IUUC-Rno-104960	Rattus norvegicus	84.41	0.00e+00	977.00
IUUC-Sce-106290	Saccharomyces cerevisiae	42.24	2.00e-114	405.00
IUUC-Sha-107603	Sarcophilus harrisii	72.81	0.00e+00	766.00
IUUC-Sja-107772	Schizosaccharomyces japonicus	40.38	9.00e-109	387.00
IUUC-Spo-108202	Schizosaccharomyces pombe	40.53	3.00e-108	385.00
IUUC-Ssl-108535	Sclerotinia sclerotiorum	60.48	4.00e-104	372.00
IUUC-Smo-109309	Selaginella moellendorffii	46.59	4.00e-124	438.00
IUUC-Sit-109745	Setaria italica	49.49	2.00e-128	452.00
IUUC-Sly-110890	Solanum lycopersicum	48.70	1.00e-127	449.00
IUUC-Stu-112144	Solanum tuberosum	46.41	4.00e-119	421.00
IUUC-Sar-113521	Sorex araneus	63.62	8.00e-177	613.00
IUUC-Sbi-114764	Sorghum bicolor	48.89	7.00e-129	454.00
IUUC-Sre-115141	Sporisorium reilianum	66.19	1.00e-114	407.00
IUUC-Ssc-115732	Sus scrofa	72.43	0.00e+00	738.00
IUUC-Tgu-117190	Taeniopygia guttata	72.58	0.00e+00	756.00
IUUC-Tsy-119503	Tarsius syrichta	81.87	0.00e+00	870.00
IUUC-Tni-119880	Tetraodon nigroviridis	95.17	0.00e+00	1079.00
IUUC-Tca-121386	Theobroma cacao	48.98	9.00e-129	453.00
IUUC-Tre-122070	Trichoderma reesei	48.13	1.00e-103	370.00
IUUC-Tvi-122305	Trichoderma virens	48.33	2.00e-103	370.00
IUUC-Tae-124621	Triticum aestivum	48.05	8.00e-126	443.00
IUUC-Tur-126416	Triticum urartu	47.31	1.00e-125	443.00
IUUC-Tbe-127791	Tupaia belangeri	82.61	4.00e-108	384.00
IUUC-Ttr-129224	Tursiops truncatus	71.55	0.00e+00	761.00
IUUC-Uma-129372	Ustilago maydis	66.19	4.00e-114	405.00
IUUC-Vda-129819	Verticillium dahliae	53.47	4.00e-84	305.00
IUUC-Vpa-130220	Vicugna pacos	84.54	0.00e+00	917.00
IUUC-Vvi-131649	Vitis vinifera	49.19	9.00e-127	447.00
IUUC-Xtr-132954	Xenopus tropicalis	86.94	0.00e+00	984.00
IUUC-Xma-134119	Xiphophorus maculatus	95.51	0.00e+00	1075.00
IUUC-Yli-134422	Yarrowia lipolytica	45.20	1.00e-116	413.00
IUUC-Zma-135621	Zea mays	61.06	5.00e-121	428.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence