iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-027357

Ensembl Protein ID

ENSDARP00000035513.5

UniProt Accession

Q6NV25; SMO3L_DANRE

Genbank Protein ID

AAH68341.1; AAH58303.1

Protein Name

Small ubiquitin-related modifier 3-like; SUMO-3-A

Genbank Nucleotide ID

BC068341; BC058303

Gene Name

sumo3a; sumo3l; sumo3; zgc:65847; zgc:85643

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000028119.7	ENSDART00000035905.5	ENSDARP00000035513.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UBL/SUMO	5.20e-32	111.3	14	92

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UBL/SUMO

   S: 6    kapvslkvagqdGsevlfklklsaqlkklmeavYvkrinldensvrfvfngqkireqetpeelevededkiellcqksGG 85
             +++lkvagqdGs v+fk+k++++l+klm+a Y++r++l+ +++rf+f+gq+i+e++tp++le+eded+i++++q++GG
   Q: 14   NDHINLKVAGQDGSVVQFKIKRHTPLSKLMKA-YCERQGLSIRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGG 92
           689*****************************.**********************************************9 PP

Organism

Danio rerio

Functional Description
(View)

Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex sae1-sae2 and linkage to the E2 enzyme ube2i (By similarity).

Protein Sequence
(Fasta)

MSEDKPKEGV KTENDHINLK VAGQDGSVVQ FKIKRHTPLS KLMKAYCERQ GLSIRQIRFR 60
FDGQPINETD TPAQLEMEDE DTIDVFQQQT GGSC 94

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Nucleotide Sequence
(Fasta)

CTCTCGTGGA CATCACGTGA CCAGAAACCA ACCAATCGTT GATAAAGTAG GTAAAGGAAA 60
GCGCGTCCCC GTCCGCAGCT GTGTTGCTCT ACAGTGTGGA GAGCGCGTCT TGTGTTCTAA 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-1017--Isopeptide bond
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0832--Ubl conjugation
KW-0833--Ubl conjugation pathway

Interpro

IPR022617--Rad60/SUMO-like_dom
IPR033950--Sumo
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50053--UBIQUITIN_2

Pfam

PF11976--Rad60-SLD

SMART

SM00213--UBQ

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0016605--C:PML body
GO:0031386--F:protein tag
GO:0043009--P:chordate embryonic development
GO:0060216--P:definitive hemopoiesis
GO:0016925--P:protein sumoylation

KEGG

dre:406398

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001056	Aegilops tauschii	46.24	1.00e-16	78.60
IUUC-Atr-002794	Amborella trichopoda	57.69	1.00e-20	91.30
IUUC-Ani-009300	Aspergillus nidulans	48.72	3.00e-16	76.30
IUUC-Ame-011304	Astyanax mexicanus	100.00	1.00e-51	193.00
IUUC-Bci-013625	Botrytis cinerea	47.06	3.00e-18	83.20
IUUC-Bdi-014847	Brachypodium distachyon	53.33	2.00e-21	93.60
IUUC-Dse-031390	Dothistroma septosporum	50.55	3.00e-21	92.80
IUUC-Dme-031967	Drosophila melanogaster	72.84	4.00e-33	132.00
IUUC-Itr-048366	Ictidomys tridecemlineatus	94.57	2.00e-47	180.00
IUUC-Lpe-051129	Leersia perrieri	55.56	2.00e-23	100.00
IUUC-Mor-057132	Magnaporthe oryzae	54.43	2.00e-20	90.50
IUUC-Mpu-065686	Mustela putorius furo	97.73	7.00e-48	181.00
IUUC-Mlu-066949	Myotis lucifugus	96.55	2.00e-46	176.00
IUUC-Oan-073080	Ornithorhynchus anatinus	96.63	3.00e-47	179.00
IUUC-Oba-075425	Oryza barthii	61.54	8.00e-23	98.20
IUUC-Ogl-077346	Oryza glaberrima	61.54	8.00e-23	98.20
IUUC-Ogu-078983	Oryza glumaepatula	53.33	6.00e-21	93.20
IUUC-Oin-079503	Oryza indica	61.54	8.00e-23	98.20
IUUC-Olo-080573	Oryza longistaminata	61.54	8.00e-23	98.20
IUUC-Oni-082762	Oryza nivara	61.54	8.00e-23	98.20
IUUC-Oru-084392	Oryza rufipogon	61.54	8.00e-23	98.20
IUUC-Osa-086070	Oryza sativa	61.54	8.00e-23	98.20
IUUC-Oar-089406	Ovis aries	97.70	3.00e-47	179.00
IUUC-Sha-106682	Sarcophilus harrisii	95.45	3.00e-47	179.00
IUUC-Sly-110855	Solanum lycopersicum	55.70	3.00e-21	93.20
IUUC-Tca-120927	Theobroma cacao	57.14	2.00e-20	91.30

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence