iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-035741

Ensembl Protein ID

ENSFCAP00000012531.3

UniProt Accession

M3WIZ8; M3WIZ8_FELCA

Genbank Protein ID

ENSFCAP00000012531

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02009112

Gene Name

PIK3R4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000013508.3	ENSFCAT00000013513.3	ENSFCAP00000012531.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-17	63.4	992	1020

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclafsd.tllvsGsdDgtikvWD 29
           H++ v+ ++ sd + ++++s+Dgt+k+W+
   Q: 992  HKSAVNRIRVSDeHSFATCSNDGTVKIWN 1020
           999999*99978799*************9 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MGNQLAGIAP SQILSVESYF SDIHDFEYDK SLGSTRFFKV ARAKHREGLV VVKVFAIQDP 60
TLPLTSYKQE LEELKIRLHS AQNCLPFQKA AEKASEKAAM LFRQYVRDNL YDRISTRPFL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACGTTTTAT TTTCTTCCTC CAGGCGTCTG CGTGAAGCCA CGCCCCTTCC TCGTTTCCTA 60
GCAACCAACT CCACCACCAT TCGCTTGCTT CCTTAAACCT CTCTCCGTCG TCACTTCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR021133--HEAT_type_2
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR008271--Ser/Thr_kinase_AS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50077--HEAT_REPEAT
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00069--Pkinase
PF00400--WD40

SMART

SM00220--S_TKc
SM00320--WD40

Gene Ontology

GO:0005930--C:axoneme
GO:0005770--C:late endosome
GO:0015630--C:microtubule cytoskeleton
GO:0005643--C:nuclear pore
GO:0071561--C:nucleus-vacuole junction
GO:0034271--C:phosphatidylinositol 3-kinase complex, class III, type I
GO:0034272--C:phosphatidylinositol 3-kinase complex, class III, type II
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0042149--P:cellular response to glucose starvation
GO:0045324--P:late endosome to vacuole transport
GO:0016236--P:macroautophagy
GO:0030242--P:pexophagy
GO:0043552--P:positive regulation of phosphatidylinositol 3-kinase activity
GO:0006468--P:protein phosphorylation
GO:0006623--P:protein targeting to vacuole
GO:0032801--P:receptor catabolic process
GO:0032465--P:regulation of cytokinesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000213	Aegilops tauschii	31.87	6.00e-44	173.00
IUUC-Aml-001659	Ailuropoda melanoleuca	98.23	0.00e+00	2697.00
IUUC-Atr-002968	Amborella trichopoda	45.60	8.00e-45	176.00
IUUC-Apl-003418	Anas platyrhynchos	91.06	0.00e+00	2559.00
IUUC-Aca-004344	Anolis carolinensis	90.56	0.00e+00	2292.00
IUUC-Aly-006107	Arabidopsis lyrata	46.06	7.00e-69	256.00
IUUC-Ath-007260	Arabidopsis thaliana	46.36	2.00e-69	258.00
IUUC-Ago-007721	Ashbya gossypii	24.38	6.00e-57	216.00
IUUC-Acl-008378	Aspergillus clavatus	37.36	6.00e-147	515.00
IUUC-Afl-008632	Aspergillus flavus	35.97	1.00e-140	494.00
IUUC-Afu-009020	Aspergillus fumigatus	36.22	2.00e-140	494.00
IUUC-Ani-009204	Aspergillus nidulans	35.74	7.00e-131	462.00
IUUC-Ang-009811	Aspergillus niger	35.30	2.00e-138	487.00
IUUC-Aor-010168	Aspergillus oryzae	35.97	1.00e-140	494.00
IUUC-Ate-010556	Aspergillus terreus	35.22	1.00e-137	484.00
IUUC-Ame-011955	Astyanax mexicanus	81.20	0.00e+00	1818.00
IUUC-Bgr-012050	Blumeria graminis	36.65	3.00e-139	489.00
IUUC-Bta-012432	Bos taurus	96.54	0.00e+00	2690.00
IUUC-Bci-013846	Botrytis cinerea	34.52	5.00e-141	496.00
IUUC-Bdi-015072	Brachypodium distachyon	42.41	7.00e-65	243.00
IUUC-Bol-015314	Brassica oleracea	46.67	1.00e-69	258.00
IUUC-Bra-017476	Brassica rapa	46.67	1.00e-69	258.00
IUUC-Cel-018550	Caenorhabditis elegans	31.73	1.00e-83	305.00
IUUC-Cja-019538	Callithrix jacchus	96.61	0.00e+00	2695.00
IUUC-Cfa-020483	Canis familiaris	98.23	0.00e+00	2702.00
IUUC-Cpo-021392	Cavia porcellus	96.24	0.00e+00	2677.00
IUUC-Csa-024112	Chlorocebus sabaeus	97.35	0.00e+00	2712.00
IUUC-Cho-025015	Choloepus hoffmanni	90.53	0.00e+00	946.00
IUUC-Cin-025209	Ciona intestinalis	41.37	0.00e+00	1064.00
IUUC-Csv-026334	Ciona savignyi	42.00	0.00e+00	885.00
IUUC-Cgl-026447	Colletotrichum gloeosporioides	35.69	9.00e-142	498.00
IUUC-Cne-026999	Cryptococcus neoformans	39.41	9.00e-114	405.00
IUUC-Dre-028662	Danio rerio	81.65	0.00e+00	2286.00
IUUC-Dno-029545	Dasypus novemcinctus	94.92	0.00e+00	2628.00
IUUC-Dor-030941	Dipodomys ordii	65.06	0.00e+00	701.00
IUUC-Dse-031455	Dothistroma septosporum	36.53	5.00e-136	479.00
IUUC-Dme-031726	Drosophila melanogaster	40.44	0.00e+00	983.00
IUUC-Ete-033147	Echinops telfairi	94.50	0.00e+00	1011.00
IUUC-Eca-034025	Equus caballus	97.79	0.00e+00	2716.00
IUUC-Eeu-034480	Erinaceus europaeus	90.40	0.00e+00	1522.00
IUUC-Fal-037666	Ficedula albicollis	90.02	0.00e+00	2533.00
IUUC-Fox-037818	Fusarium oxysporum	33.75	3.00e-125	443.00
IUUC-Fso-038086	Fusarium solani	34.48	8.00e-129	455.00
IUUC-Gmo-038804	Gadus morhua	81.41	0.00e+00	724.00
IUUC-Ggr-039800	Gaeumannomyces graminis	35.71	1.00e-132	468.00
IUUC-Gga-041251	Gallus gallus	90.37	0.00e+00	2001.00
IUUC-Gac-042376	Gasterosteus aculeatus	78.88	0.00e+00	2209.00
IUUC-Gma-044095	Glycine max	45.30	2.00e-71	264.00
IUUC-Ggo-044506	Gorilla gorilla	96.69	0.00e+00	2687.00
IUUC-Hsa-045871	Homo sapiens	97.28	0.00e+00	2704.00
IUUC-Hvu-047648	Hordeum vulgare	31.01	2.00e-45	178.00
IUUC-Itr-048082	Ictidomys tridecemlineatus	99.00	0.00e+00	1211.00
IUUC-Kpa-049390	Komagataella pastoris	32.57	4.00e-126	446.00
IUUC-Lch-050284	Latimeria chalumnae	85.30	0.00e+00	2310.00
IUUC-Lpe-050880	Leersia perrieri	41.19	9.00e-63	236.00
IUUC-Loc-052815	Lepisosteus oculatus	81.98	0.00e+00	2290.00
IUUC-Lma-053324	Leptosphaeria maculans	36.79	8.00e-145	509.00
IUUC-Laf-054204	Loxodonta africana	85.15	0.00e+00	2280.00
IUUC-Mcc-054612	Macaca mulatta	97.28	0.00e+00	2706.00
IUUC-Meu-056227	Macropus eugenii	86.30	0.00e+00	850.00
IUUC-Mor-057094	Magnaporthe oryzae	36.51	8.00e-134	472.00
IUUC-Mtr-058550	Medicago truncatula	43.37	2.00e-70	261.00
IUUC-Mla-058893	Melampsora laricipopulina	34.60	3.00e-127	450.00
IUUC-Mga-059474	Meleagris gallopavo	90.37	0.00e+00	2414.00
IUUC-Mvi-060227	Microbotryum violaceum	45.01	4.00e-82	300.00
IUUC-Mmr-061543	Microcebus murinus	89.76	0.00e+00	2408.00
IUUC-Mdo-062129	Monodelphis domestica	93.22	0.00e+00	2499.00
IUUC-Mmu-064381	Mus musculus	94.55	0.00e+00	2637.00
IUUC-Mac-064455	Musa acuminata	38.15	5.00e-122	432.00
IUUC-Mpu-066151	Mustela putorius furo	99.59	0.00e+00	998.00
IUUC-Mlu-067824	Myotis lucifugus	97.28	0.00e+00	2702.00
IUUC-Nfi-068241	Neosartorya fischeri	37.43	1.00e-143	504.00
IUUC-Ncr-068964	Neurospora crassa	36.20	1.00e-138	488.00
IUUC-Nle-069152	Nomascus leucogenys	97.35	0.00e+00	2707.00
IUUC-Opr-070870	Ochotona princeps	85.55	0.00e+00	1429.00
IUUC-Ont-071293	Oreochromis niloticus	80.41	0.00e+00	2257.00
IUUC-Oan-072852	Ornithorhynchus anatinus	87.11	0.00e+00	2395.00
IUUC-Ocu-074727	Oryctolagus cuniculus	96.98	0.00e+00	2679.00
IUUC-Oba-075932	Oryza barthii	39.18	2.00e-62	234.00
IUUC-Obr-076424	Oryza brachyantha	47.39	5.00e-60	226.00
IUUC-Ogl-077491	Oryza glaberrima	39.18	2.00e-62	234.00
IUUC-Ogu-078933	Oryza glumaepatula	35.46	9.00e-111	395.00
IUUC-Oin-079604	Oryza indica	43.55	5.00e-68	253.00
IUUC-Olo-080850	Oryza longistaminata	35.81	2.00e-115	410.00
IUUC-Ome-081860	Oryza meridionalis	43.55	6.00e-68	253.00
IUUC-Oni-082895	Oryza nivara	39.18	3.00e-62	234.00
IUUC-Opu-083741	Oryza punctata	43.27	1.00e-66	248.00
IUUC-Oru-084616	Oryza rufipogon	38.87	8.00e-62	233.00
IUUC-Osa-085941	Oryza sativa	27.59	2.00e-34	140.00
IUUC-Ola-087357	Oryzias latipes	84.94	3.00e-156	544.00
IUUC-Olu-087659	Ostreococcus lucimarinus	30.46	1.00e-85	312.00
IUUC-Oga-088555	Otolemur garnettii	97.20	0.00e+00	2682.00
IUUC-Oar-089304	Ovis aries	95.53	0.00e+00	1331.00
IUUC-Ptr-091140	Pan troglodytes	97.35	0.00e+00	2706.00
IUUC-Pan-092413	Papio anubis	96.95	0.00e+00	2596.00
IUUC-Psi-093210	Pelodiscus sinensis	91.11	0.00e+00	2563.00
IUUC-Pma-094674	Petromyzon marinus	56.25	0.00e+00	716.00
IUUC-Pno-094969	Phaeosphaeria nodorum	31.39	8.00e-146	511.00
IUUC-Ppa-096017	Physcomitrella patens	45.56	2.00e-74	274.00
IUUC-Pfo-096077	Poecilia formosa	80.19	0.00e+00	2211.00
IUUC-Pab-098269	Pongo abelii	96.39	0.00e+00	2687.00
IUUC-Pop-100052	Populus trichocarpa	43.67	1.00e-62	235.00
IUUC-Pca-100377	Procavia capensis	90.94	0.00e+00	2412.00
IUUC-Ppe-101445	Prunus persica	46.08	6.00e-71	263.00
IUUC-Pva-102198	Pteropus vampyrus	98.79	0.00e+00	1815.00
IUUC-Pgr-103544	Puccinia graminis	46.86	4.00e-78	286.00
IUUC-Ptt-103964	Puccinia triticina	46.54	5.00e-75	276.00
IUUC-Pte-104196	Pyrenophora teres	37.15	5.00e-137	482.00
IUUC-Pyt-104544	Pyrenophora triticirepentis	37.19	1.00e-135	478.00
IUUC-Rno-105256	Rattus norvegicus	94.55	0.00e+00	2638.00
IUUC-Sce-106295	Saccharomyces cerevisiae	33.25	2.00e-111	397.00
IUUC-Sha-107597	Sarcophilus harrisii	92.44	0.00e+00	2528.00
IUUC-Sja-107781	Schizosaccharomyces japonicus	32.95	1.00e-98	355.00
IUUC-Spo-108031	Schizosaccharomyces pombe	43.84	1.00e-71	265.00
IUUC-Ssl-108579	Sclerotinia sclerotiorum	35.64	5.00e-135	476.00
IUUC-Smo-108679	Selaginella moellendorffii	43.45	4.00e-76	280.00
IUUC-Sit-110765	Setaria italica	41.26	6.00e-62	233.00
IUUC-Sly-111527	Solanum lycopersicum	43.65	3.00e-71	264.00
IUUC-Stu-112899	Solanum tuberosum	43.65	1.00e-71	265.00
IUUC-Sar-112986	Sorex araneus	96.47	0.00e+00	2679.00
IUUC-Sbi-114604	Sorghum bicolor	40.75	5.00e-65	243.00
IUUC-Sre-115191	Sporisorium reilianum	43.38	1.00e-63	239.00
IUUC-Ssc-115440	Sus scrofa	95.66	0.00e+00	2637.00
IUUC-Tgu-116633	Taeniopygia guttata	90.17	0.00e+00	2536.00
IUUC-Tru-118439	Takifugu rubripes	78.77	0.00e+00	2225.00
IUUC-Tsy-119472	Tarsius syrichta	90.60	0.00e+00	1441.00
IUUC-Tni-119808	Tetraodon nigroviridis	74.51	0.00e+00	2024.00
IUUC-Tca-121648	Theobroma cacao	46.99	2.00e-72	268.00
IUUC-Tre-122161	Trichoderma reesei	34.13	1.00e-121	431.00
IUUC-Tvi-122575	Trichoderma virens	33.15	5.00e-113	402.00
IUUC-Tae-123381	Triticum aestivum	45.98	4.00e-65	243.00
IUUC-Tur-126291	Triticum urartu	43.55	6.00e-66	246.00
IUUC-Tme-126979	Tuber melanosporum	37.24	2.00e-147	517.00
IUUC-Tbe-127576	Tupaia belangeri	80.17	0.00e+00	917.00
IUUC-Ttr-129106	Tursiops truncatus	99.24	0.00e+00	1325.00
IUUC-Uma-129633	Ustilago maydis	42.24	8.00e-72	266.00
IUUC-Vda-130001	Verticillium dahliae	34.71	3.00e-128	453.00
IUUC-Vpa-130733	Vicugna pacos	90.30	0.00e+00	1326.00
IUUC-Vvi-131318	Vitis vinifera	44.03	3.00e-69	257.00
IUUC-Xtr-131908	Xenopus tropicalis	86.09	0.00e+00	2433.00
IUUC-Xma-133331	Xiphophorus maculatus	80.04	0.00e+00	2224.00
IUUC-Yli-134651	Yarrowia lipolytica	36.96	2.00e-119	423.00
IUUC-Zma-135850	Zea mays	40.48	7.00e-66	246.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence