iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090345

Ensembl Protein ID

ENSOARP00000008977.1

UniProt Accession

W5PEW2; W5PEW2_SHEEP

Genbank Protein ID

ENSOARP00000008977

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01057231

Gene Name

USP48

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000008364.1	ENSOART00000009107.1	ENSOARP00000008977.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.70e-73	247.3	44	375
ULD/UDP/UBQ/UBQ_Other	1.00e-10	41.5	904	966

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle........kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkea 81
           +Gl+Nlg+tCY+N  LQ+ +   elr++l               ++ee+ + + ++++++lq lf+ l++s++++++p+ ++kal+   
   Q: 44   VGLTNLGATCYVNTFLQVWFLNLELRQALYLcpstctdyMMGDGIQEEKVDYEPQTICEHLQYLFALLQNSNRRYIDPSGFVKALG--- 129
           6*****************************9777777776666666666688899******************************9... PP
   S: 82   eefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfl 170
             +++ +qqDaqEf + +++ le++l                       +++k+   ++++++ F g++   ++c++c+++s+  ++f+
   Q: 130  --LDTGQQQDAQEFSKLFMSLLEDTL-----------------------SKQKNPDVRNIVQQQFCGEYAYVTVCNQCGRESKLLSKFY 193
           ..78899*******************.......................457889999******************************* PP
   S: 171  dlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleL 259
           +l+l+++g++     +l+dc+++f kee+leg+n+y+ce+c++kq+a++k++l +lP +L l+L+Rf f++++++++k+n+++ f + L
   Q: 194  ELELNIQGHK-----QLTDCISEFLKEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFVFDRQTGHKKKLNTYIGFSEIL 277
           **********.....9************************************************************************* PP
   S: 260  dlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn.ekgkWllfdDskVtevkeeevleetg................... 327
           d++p+++++      ++ YeL+av++H G s+ sGHY+a+vk+ ++g+W++f+D+ +++++ ++ +   +                   
   Q: 278  DMEPYVEHKGG----SYVYELSAVLIHRGvSAYSGHYIAHVKDpQSGEWYKFNDEDIEKMEGKKLQLGIEedlaepsksqtrkpkcgkg 362
           ******99554....79**************************44555************9999998665999**************** PP
   S: 328  ....staYvlfYk 336
               ++aY+l+Y+
   Q: 363  thcsRNAYMLVYR 375
           ************8 PP

ULD/UDP/UBQ/UBQ_Other

   S: 16   k...vnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglkdgstihllekks 74
           k   v+   t +eLK +i +++++ p +q+L ++GkiL +d+ tL+ +g+ ++s+i+l  +++
   Q: 904  KallVSANQTLKELKIQIMHAFSVAPFDQNLSIDGKILsDDCATLGTLGVIPESVILLKADEP 966
           344489999************************************************988775 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

RNCKGNPNCL VGIGEHIWLG EIDENSFHNI DDPNCERRKK NSFVGLTNLG ATCYVNTFLQ 60
VWFLNLELRQ ALYLCPSTCT DYMMGDGIQE EKVDYEPQTI CEHLQYLFAL LQNSNRRYID 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGTGGGG GCTCCGGTTG GGGTGGGGAA GGAAGACGGC GACCCATTGC GTGCCTCTCT 60
CCGGCTTGGA GACAACCGGG TGGAGGGCTT CCTCCTCTCC GCCTTCTGGG CGACCCGGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR033841--USP48
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS50053--UBIQUITIN_2
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005739--C:mitochondrion
GO:0005654--C:nucleoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000130	Aegilops tauschii	31.77	3.00e-76	280.00
IUUC-Aml-001357	Ailuropoda melanoleuca	98.19	0.00e+00	1961.00
IUUC-Atr-002976	Amborella trichopoda	31.85	4.00e-75	276.00
IUUC-Apl-003773	Anas platyrhynchos	87.47	0.00e+00	1688.00
IUUC-Aca-004466	Anolis carolinensis	80.43	0.00e+00	862.00
IUUC-Aly-006249	Arabidopsis lyrata	30.08	3.00e-67	250.00
IUUC-Ath-006700	Arabidopsis thaliana	31.11	3.00e-76	280.00
IUUC-Ame-011554	Astyanax mexicanus	68.40	0.00e+00	1372.00
IUUC-Bta-012573	Bos taurus	98.59	0.00e+00	1993.00
IUUC-Bdi-014149	Brachypodium distachyon	32.56	4.00e-79	290.00
IUUC-Bol-016289	Brassica oleracea	32.24	2.00e-75	278.00
IUUC-Bra-017494	Brassica rapa	32.13	2.00e-79	291.00
IUUC-Cel-018662	Caenorhabditis elegans	27.65	7.00e-29	123.00
IUUC-Cja-019991	Callithrix jacchus	95.92	0.00e+00	1955.00
IUUC-Cfa-020294	Canis familiaris	97.89	0.00e+00	1992.00
IUUC-Cpo-021706	Cavia porcellus	94.47	0.00e+00	1921.00
IUUC-Cre-022636	Chlamydomonas reinhardtii	32.50	2.00e-42	169.00
IUUC-Csa-023931	Chlorocebus sabaeus	97.08	0.00e+00	1967.00
IUUC-Cho-024566	Choloepus hoffmanni	98.19	2.00e-160	560.00
IUUC-Cin-025307	Ciona intestinalis	49.24	5.00e-68	250.00
IUUC-Csv-026006	Ciona savignyi	37.16	9.00e-143	501.00
IUUC-Cne-027065	Cryptococcus neoformans	28.19	1.00e-68	255.00
IUUC-Dre-027624	Danio rerio	68.81	0.00e+00	1416.00
IUUC-Dno-029633	Dasypus novemcinctus	97.32	0.00e+00	1312.00
IUUC-Dor-030809	Dipodomys ordii	73.08	0.00e+00	1100.00
IUUC-Ete-032818	Echinops telfairi	90.73	0.00e+00	949.00
IUUC-Eca-033692	Equus caballus	97.59	0.00e+00	1972.00
IUUC-Eeu-035185	Erinaceus europaeus	74.55	0.00e+00	794.00
IUUC-Fca-035676	Felis catus	97.28	0.00e+00	1984.00
IUUC-Fal-036913	Ficedula albicollis	87.14	0.00e+00	1761.00
IUUC-Gmo-038532	Gadus morhua	65.25	0.00e+00	1325.00
IUUC-Gga-041041	Gallus gallus	87.14	0.00e+00	1756.00
IUUC-Gac-042570	Gasterosteus aculeatus	66.12	0.00e+00	1356.00
IUUC-Gma-044136	Glycine max	29.85	1.00e-86	314.00
IUUC-Ggo-045367	Gorilla gorilla	92.17	0.00e+00	1830.00
IUUC-Hsa-046019	Homo sapiens	97.28	0.00e+00	1971.00
IUUC-Hvu-047303	Hordeum vulgare	32.75	2.00e-61	229.00
IUUC-Itr-048319	Ictidomys tridecemlineatus	94.67	0.00e+00	1945.00
IUUC-Lch-049989	Latimeria chalumnae	76.29	0.00e+00	1568.00
IUUC-Lpe-051612	Leersia perrieri	32.84	5.00e-77	283.00
IUUC-Loc-052756	Lepisosteus oculatus	70.27	0.00e+00	1468.00
IUUC-Laf-054043	Loxodonta africana	95.85	0.00e+00	1961.00
IUUC-Mcc-054986	Macaca mulatta	95.83	0.00e+00	1955.00
IUUC-Meu-056228	Macropus eugenii	77.44	0.00e+00	868.00
IUUC-Mtr-058762	Medicago truncatula	29.44	3.00e-83	303.00
IUUC-Mga-059896	Meleagris gallopavo	86.41	0.00e+00	1735.00
IUUC-Mvi-060269	Microbotryum violaceum	36.93	4.00e-62	233.00
IUUC-Mmr-060887	Microcebus murinus	97.38	0.00e+00	1967.00
IUUC-Mdo-062506	Monodelphis domestica	93.06	0.00e+00	1894.00
IUUC-Mmu-063642	Mus musculus	91.40	0.00e+00	1882.00
IUUC-Mac-064896	Musa acuminata	32.41	4.00e-74	273.00
IUUC-Mpu-066194	Mustela putorius furo	98.19	0.00e+00	1976.00
IUUC-Mlu-067233	Myotis lucifugus	96.40	0.00e+00	1964.00
IUUC-Nle-069052	Nomascus leucogenys	96.22	0.00e+00	1957.00
IUUC-Opr-070890	Ochotona princeps	94.39	0.00e+00	1153.00
IUUC-Ont-071450	Oreochromis niloticus	64.75	0.00e+00	1294.00
IUUC-Oan-073252	Ornithorhynchus anatinus	89.95	0.00e+00	1059.00
IUUC-Ocu-073796	Oryctolagus cuniculus	96.60	0.00e+00	1763.00
IUUC-Oba-075563	Oryza barthii	33.92	1.00e-78	288.00
IUUC-Obr-076394	Oryza brachyantha	32.84	1.00e-79	291.00
IUUC-Ogl-077339	Oryza glaberrima	39.26	3.00e-39	155.00
IUUC-Ogu-079007	Oryza glumaepatula	33.33	2.00e-72	268.00
IUUC-Oin-079997	Oryza indica	33.92	6.00e-79	289.00
IUUC-Olo-080364	Oryza longistaminata	33.92	7.00e-79	288.00
IUUC-Ome-081165	Oryza meridionalis	33.33	5.00e-73	269.00
IUUC-Oni-083026	Oryza nivara	33.92	5.00e-79	289.00
IUUC-Opu-083284	Oryza punctata	34.19	1.00e-72	268.00
IUUC-Oru-084797	Oryza rufipogon	33.92	7.00e-79	289.00
IUUC-Osa-086221	Oryza sativa	39.26	3.00e-39	155.00
IUUC-Ola-086568	Oryzias latipes	66.18	0.00e+00	1363.00
IUUC-Oga-088687	Otolemur garnettii	95.52	0.00e+00	1946.00
IUUC-Ptr-090734	Pan troglodytes	97.18	0.00e+00	1970.00
IUUC-Pan-091704	Papio anubis	93.58	0.00e+00	1878.00
IUUC-Psi-092937	Pelodiscus sinensis	87.16	0.00e+00	1610.00
IUUC-Ppa-095808	Physcomitrella patens	28.78	4.00e-67	250.00
IUUC-Pab-098129	Pongo abelii	97.18	0.00e+00	1970.00
IUUC-Pop-099738	Populus trichocarpa	32.07	8.00e-74	272.00
IUUC-Pca-100647	Procavia capensis	97.90	2.00e-169	590.00
IUUC-Ppe-102091	Prunus persica	27.26	3.00e-83	303.00
IUUC-Pva-102719	Pteropus vampyrus	96.78	0.00e+00	1952.00
IUUC-Rno-105363	Rattus norvegicus	93.16	0.00e+00	1907.00
IUUC-Sha-107620	Sarcophilus harrisii	89.94	0.00e+00	1847.00
IUUC-Smo-109487	Selaginella moellendorffii	27.77	2.00e-83	303.00
IUUC-Sit-110683	Setaria italica	32.57	5.00e-78	286.00
IUUC-Sly-111377	Solanum lycopersicum	30.97	5.00e-76	279.00
IUUC-Stu-111969	Solanum tuberosum	31.47	3.00e-67	249.00
IUUC-Sar-113099	Sorex araneus	95.89	0.00e+00	1731.00
IUUC-Sbi-113833	Sorghum bicolor	42.33	3.00e-57	215.00
IUUC-Ssc-115279	Sus scrofa	91.13	0.00e+00	1371.00
IUUC-Tgu-117519	Taeniopygia guttata	84.14	0.00e+00	1680.00
IUUC-Tru-117651	Takifugu rubripes	65.10	0.00e+00	1342.00
IUUC-Tsy-119201	Tarsius syrichta	93.76	0.00e+00	1811.00
IUUC-Tni-120840	Tetraodon nigroviridis	66.54	0.00e+00	1363.00
IUUC-Tca-121674	Theobroma cacao	30.64	4.00e-82	299.00
IUUC-Tae-125814	Triticum aestivum	32.35	2.00e-76	281.00
IUUC-Tur-126599	Triticum urartu	32.13	1.00e-75	278.00
IUUC-Tbe-127782	Tupaia belangeri	87.89	0.00e+00	1078.00
IUUC-Ttr-128312	Tursiops truncatus	96.38	0.00e+00	1941.00
IUUC-Vpa-130348	Vicugna pacos	97.59	0.00e+00	1968.00
IUUC-Vvi-131353	Vitis vinifera	31.99	8.00e-80	292.00
IUUC-Xtr-132172	Xenopus tropicalis	70.84	0.00e+00	1346.00
IUUC-Xma-133263	Xiphophorus maculatus	67.95	0.00e+00	1340.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence