iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000008504.3	ENSMMUT00000042642.2	ENSMMUP00000035650.2
ENSMMUG00000008504.3	ENSMMUT00000011888.3	ENSMMUP00000011148.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.10e-35	118.8	184	221
UBD/Beta-Prp	1.10e-54	186.8	286	543

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH + v+c+af  + +++ +GsdD+ +k+W+++ g+ll
   Q: 184  GHLSAVYCVAFdRTgHRIFTGSDDCLVKIWSTHNGRLL 221
           8**********955599***************999987 PP

UBD/Beta-Prp

   S: 22   ksllatgsrdgtikvwdvttgkl......lrslsgheaevtavk..fspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvlsl 100
           +++++++++dgt+  w+++ ++l      l+  ++  ++v+ ++  fs  g +l+tgs+D++i+ +   +++++ +  l+ h+d+v s+
   Q: 286  QRYMVSTGADGTVCFWQWDLESLkfsprpLKFTEKPRPGVQMLCssFSVGGMFLATGSTDHVIRMYflGFEAPEKIAELESHTDKVDSI 374
           689*****************99999988777778888888755522888888**************99999****************** PP
   S: 101  sfspsgdklvsGshdrtirvwdletgqclee...............tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrt 174
           +f+ +gd+++sGs+d t+r+w  e+ ++ +                 ++  +  v++++++++++++v++ +D ++++W++ tg+ll+ 
   Q: 375  QFCNNGDRFLSGSRDGTARIWRFEQLEWRSIlldmatrisgdlsseEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHN 463
           **************************99998999********998877777888*********************************** PP
   S: 175  ltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriW 249
           l g h d v  l+   fds  + ++s+++dg++ +wd+ +g+ ++ + +         v + +fs+++++++++ s+g + i+
   Q: 464  LLG-HADEVFVLEthpFDS--RIMLSAGHDGSIFIWDITKGTKMKHYFNMIegqghGAVFDCKFSQDGQHFACTDSHGHLLIF 543
           **9.*********555555..99****************999977766544444456677789999*****999999998886 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MAEPSSARRP VPLIESELYF LIARYLSAGP CRRAAQVLVQ ELEQYQLLPK RLDWEGNEHN 60
RSYEELVLSN KHVAPDHLLQ ICQRIGPMLD KEIPPSISRV TSLLGAGRQS LLRTAKDCRH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGCGCGCC TGAGGAGAGG GGACGCCAGC CCGGTCAGGC CTCGGCGCGG CCTACACGCT 60
CCGCTCGCTC GCTCGCTCCC GCCTCCCGCC CCGTGTCCGG CCATGGCGGA GCCCTCGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

KEGG

mcc:715714

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001113	Aegilops tauschii	30.52	2.00e-62	235.00
IUUC-Aml-002332	Ailuropoda melanoleuca	84.60	0.00e+00	3316.00
IUUC-Apl-004083	Anas platyrhynchos	69.45	0.00e+00	1962.00
IUUC-Aca-004348	Anolis carolinensis	72.75	0.00e+00	1959.00
IUUC-Aly-006517	Arabidopsis lyrata	30.28	4.00e-73	270.00
IUUC-Ath-006577	Arabidopsis thaliana	30.13	2.00e-72	268.00
IUUC-Ame-010718	Astyanax mexicanus	70.37	0.00e+00	1177.00
IUUC-Bta-013217	Bos taurus	88.50	0.00e+00	3694.00
IUUC-Bdi-014797	Brachypodium distachyon	29.25	2.00e-59	224.00
IUUC-Bol-015737	Brassica oleracea	29.44	1.00e-73	272.00
IUUC-Bra-017961	Brassica rapa	29.40	5.00e-73	270.00
IUUC-Cja-019966	Callithrix jacchus	94.65	0.00e+00	3987.00
IUUC-Cfa-021037	Canis familiaris	88.71	0.00e+00	3622.00
IUUC-Cpo-021934	Cavia porcellus	91.81	0.00e+00	2776.00
IUUC-Cre-023003	Chlamydomonas reinhardtii	34.15	1.00e-34	142.00
IUUC-Csa-023352	Chlorocebus sabaeus	99.31	0.00e+00	3910.00
IUUC-Cho-024690	Choloepus hoffmanni	79.08	0.00e+00	1355.00
IUUC-Dre-028205	Danio rerio	67.33	0.00e+00	1151.00
IUUC-Dno-028938	Dasypus novemcinctus	84.55	0.00e+00	3559.00
IUUC-Dme-031752	Drosophila melanogaster	49.84	0.00e+00	671.00
IUUC-Eca-034349	Equus caballus	89.22	0.00e+00	3523.00
IUUC-Fca-035485	Felis catus	82.62	0.00e+00	3101.00
IUUC-Fal-037307	Ficedula albicollis	77.67	0.00e+00	2299.00
IUUC-Gma-043340	Glycine max	30.22	1.00e-70	262.00
IUUC-Ggo-045500	Gorilla gorilla	97.62	0.00e+00	4087.00
IUUC-Hsa-046350	Homo sapiens	97.89	0.00e+00	4110.00
IUUC-Itr-047962	Ictidomys tridecemlineatus	95.07	0.00e+00	1167.00
IUUC-Lch-049662	Latimeria chalumnae	71.24	0.00e+00	2071.00
IUUC-Lpe-051619	Leersia perrieri	31.09	3.00e-70	261.00
IUUC-Laf-053848	Loxodonta africana	87.06	0.00e+00	3558.00
IUUC-Meu-056739	Macropus eugenii	79.77	0.00e+00	1117.00
IUUC-Mtr-058094	Medicago truncatula	30.52	3.00e-72	267.00
IUUC-Mga-060165	Meleagris gallopavo	77.82	0.00e+00	2307.00
IUUC-Mmr-061227	Microcebus murinus	91.78	0.00e+00	3835.00
IUUC-Mdo-062074	Monodelphis domestica	83.11	0.00e+00	2469.00
IUUC-Mmu-064075	Mus musculus	83.03	0.00e+00	3015.00
IUUC-Mac-065343	Musa acuminata	30.87	3.00e-75	277.00
IUUC-Mpu-066643	Mustela putorius furo	90.25	0.00e+00	3008.00
IUUC-Mlu-067735	Myotis lucifugus	86.13	0.00e+00	3485.00
IUUC-Nle-069402	Nomascus leucogenys	95.80	0.00e+00	3141.00
IUUC-Oan-072954	Ornithorhynchus anatinus	70.54	0.00e+00	2850.00
IUUC-Ocu-074456	Oryctolagus cuniculus	87.85	0.00e+00	3684.00
IUUC-Oba-075709	Oryza barthii	30.03	3.00e-60	228.00
IUUC-Obr-076619	Oryza brachyantha	30.76	1.00e-70	262.00
IUUC-Opu-083233	Oryza punctata	30.32	5.00e-65	243.00
IUUC-Oru-085195	Oryza rufipogon	30.03	2.00e-60	228.00
IUUC-Olu-087745	Ostreococcus lucimarinus	28.38	5.00e-56	213.00
IUUC-Oga-087938	Otolemur garnettii	82.87	0.00e+00	3258.00
IUUC-Oar-090214	Ovis aries	87.47	0.00e+00	3548.00
IUUC-Ptr-091213	Pan troglodytes	97.89	0.00e+00	4084.00
IUUC-Pan-092444	Papio anubis	99.01	0.00e+00	4169.00
IUUC-Psi-093271	Pelodiscus sinensis	60.19	0.00e+00	2216.00
IUUC-Pma-094427	Petromyzon marinus	66.67	2.00e-132	465.00
IUUC-Ppa-095793	Physcomitrella patens	29.70	4.00e-74	274.00
IUUC-Pfo-097318	Poecilia formosa	62.98	0.00e+00	1793.00
IUUC-Pab-097573	Pongo abelii	96.48	0.00e+00	3971.00
IUUC-Pop-099672	Populus trichocarpa	30.89	2.00e-72	268.00
IUUC-Pca-100759	Procavia capensis	71.09	0.00e+00	1164.00
IUUC-Ppe-101849	Prunus persica	29.58	1.00e-74	275.00
IUUC-Pva-102782	Pteropus vampyrus	87.86	0.00e+00	3589.00
IUUC-Rno-105687	Rattus norvegicus	79.14	0.00e+00	3313.00
IUUC-Sly-111348	Solanum lycopersicum	30.41	1.00e-75	278.00
IUUC-Sar-113519	Sorex araneus	80.63	0.00e+00	1783.00
IUUC-Tgu-116513	Taeniopygia guttata	77.55	0.00e+00	2314.00
IUUC-Tsy-118921	Tarsius syrichta	89.74	0.00e+00	2035.00
IUUC-Tca-121615	Theobroma cacao	29.75	1.00e-67	252.00
IUUC-Tae-125478	Triticum aestivum	30.20	1.00e-71	265.00
IUUC-Tur-126809	Triticum urartu	30.25	3.00e-69	257.00
IUUC-Tbe-127663	Tupaia belangeri	79.37	0.00e+00	1332.00
IUUC-Ttr-128561	Tursiops truncatus	92.94	0.00e+00	2658.00
IUUC-Vpa-130444	Vicugna pacos	90.52	0.00e+00	2467.00
IUUC-Vvi-131362	Vitis vinifera	30.85	9.00e-74	273.00
IUUC-Xtr-132278	Xenopus tropicalis	55.18	0.00e+00	1587.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence