iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cin-025578

Ensembl Protein ID

ENSCINP00000017585.3

UniProt Accession

Q1RL49; Q1RL49_CIOIN

Genbank Protein ID

FAA00216.1

Protein Name

Zinc finger protein

Genbank Nucleotide ID

EAAA01001471

Gene Name

zf(ring/c6hc)-7; Ci-ZF(RING/C6HC)-7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000008622.3	ENSCINT00000017585.3	ENSCINP00000017585.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	1.20e-44	153.2	203	416

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpekleeseikellveeelykryekllleevveadaalkw 90
           C++C++ ++ ++++++  C h++Ck+C+++y+e++i+eg++t++ cp+++c +++ ++++ke  v+++ly+ryeklll++++++++++ +
   Q: 203  CNICFVDKKGTDCLQFKDCGHVYCKQCITSYFEIHISEGTITSLICPEPDCDTTALPNQVKE-AVNKDLYERYEKLLLQTTLDTMTDIVF 291
           **************************************************************.8************************** PP
   S: 91   cpapdCslvvllekeaeklevecekcgkefCveCkeewHeglsCkelkeklakteeek........................eeaeskel 156
           cp  +C+ +v++e+  e+   +c++c  +fCv+Ck ++H  + Ck ++++  k  +e+                        ++ +++ +
   Q: 292  CPLMHCQSAVIIEP--EASIGQCPSCAYAFCVHCKLAYHGVSPCKIASHEIIKLCKEYesaneekkkqmekkygrkvlckalDDRATQAW 379
           **************..577778***********************9988877777677799*********************99****** PP
   S: 157  leanskkCpkCkvyieknegCnhmtCakCkaefCwlC 193
           +++n+k+Cp C++ iek +gCn+mtC kC+a+fCw+C
   Q: 380  MNNNTKPCPGCNASIEKLDGCNKMTCYKCRAYFCWIC 416
           ************************************* PP

Organism

Ciona intestinalis

Protein Sequence
(Fasta)

MNKEDRENEL LALESILDPC SFAFNETTGR IDVFPQLQTN YIKLTSEVKS EKSCDDSHNK 60
EHFVSFLPPI QLNFALSDGY PSDEPPQFNL SCVWLSPSQL YELCLKLDEI WQKEEGNVIL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGTTTACAT CTGCGGAGTT TCATTAACCA CTTAAAAGGT GCTGTGTGCA TTTAAAATGA 60
ATAAAGAAGA TAGGGAAAAC GAACTTCTAG CCTTGGAAAG CATTCTGGAT CCTTGCTCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR006575--RWD-domain
IPR016135--UBQ-conjugating_enzyme/RWD
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50908--RWD
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR
PF05773--RWD

SMART

SM00647--IBR
SM00591--RWD

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0007165--P:signal transduction

KEGG

cin:100169999

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001130	Aegilops tauschii	32.33	2.00e-54	205.00
IUUC-Aml-001458	Ailuropoda melanoleuca	41.95	2.00e-98	351.00
IUUC-Atr-002560	Amborella trichopoda	31.81	1.00e-51	196.00
IUUC-Apl-003680	Anas platyrhynchos	41.34	2.00e-103	368.00
IUUC-Aca-005000	Anolis carolinensis	41.36	3.00e-99	353.00
IUUC-Aly-006288	Arabidopsis lyrata	30.66	2.00e-54	205.00
IUUC-Ath-006719	Arabidopsis thaliana	30.75	3.00e-54	204.00
IUUC-Acl-008213	Aspergillus clavatus	25.32	1.00e-38	153.00
IUUC-Afl-008433	Aspergillus flavus	24.50	8.00e-37	147.00
IUUC-Afu-008772	Aspergillus fumigatus	25.21	4.00e-42	164.00
IUUC-Ani-009249	Aspergillus nidulans	24.95	6.00e-36	144.00
IUUC-Ang-009757	Aspergillus niger	28.93	1.00e-42	166.00
IUUC-Aor-009963	Aspergillus oryzae	24.50	1.00e-36	146.00
IUUC-Ate-010460	Aspergillus terreus	26.14	1.00e-40	159.00
IUUC-Ame-011312	Astyanax mexicanus	42.13	5.00e-98	350.00
IUUC-Bgr-012052	Blumeria graminis	24.88	8.00e-36	144.00
IUUC-Bta-013529	Bos taurus	41.54	2.00e-100	357.00
IUUC-Bci-013729	Botrytis cinerea	23.84	8.00e-38	150.00
IUUC-Bdi-014940	Brachypodium distachyon	30.02	6.00e-48	184.00
IUUC-Bra-016998	Brassica rapa	29.91	1.00e-51	196.00
IUUC-Cel-018547	Caenorhabditis elegans	30.16	2.00e-55	208.00
IUUC-Cja-019791	Callithrix jacchus	41.79	3.00e-101	360.00
IUUC-Cfa-020403	Canis familiaris	42.13	2.00e-101	360.00
IUUC-Cpo-022229	Cavia porcellus	41.31	4.00e-95	340.00
IUUC-Cre-022601	Chlamydomonas reinhardtii	28.50	6.00e-27	112.00
IUUC-Csa-024115	Chlorocebus sabaeus	41.86	5.00e-102	363.00
IUUC-Cho-024911	Choloepus hoffmanni	41.91	3.00e-101	360.00
IUUC-Csv-026355	Ciona savignyi	65.34	8.00e-150	521.00
IUUC-Cgl-026439	Colletotrichum gloeosporioides	20.81	2.00e-31	129.00
IUUC-Cne-026782	Cryptococcus neoformans	24.58	4.00e-38	151.00
IUUC-Dre-027380	Danio rerio	43.38	3.00e-106	377.00
IUUC-Dno-029640	Dasypus novemcinctus	41.54	2.00e-100	357.00
IUUC-Dor-030681	Dipodomys ordii	41.54	4.00e-100	357.00
IUUC-Dse-031208	Dothistroma septosporum	24.49	4.00e-38	151.00
IUUC-Ete-033122	Echinops telfairi	37.77	2.00e-77	281.00
IUUC-Eca-033755	Equus caballus	42.83	3.00e-103	367.00
IUUC-Eeu-035034	Erinaceus europaeus	48.60	9.00e-26	109.00
IUUC-Fca-036461	Felis catus	42.13	3.00e-101	360.00
IUUC-Fal-037516	Ficedula albicollis	40.93	3.00e-104	370.00
IUUC-Fso-038307	Fusarium solani	22.05	1.00e-32	133.00
IUUC-Gmo-039563	Gadus morhua	39.74	6.00e-101	359.00
IUUC-Ggr-039920	Gaeumannomyces graminis	22.70	6.00e-30	124.00
IUUC-Gga-040331	Gallus gallus	41.60	9.00e-105	372.00
IUUC-Gac-042164	Gasterosteus aculeatus	40.55	6.00e-105	372.00
IUUC-Gma-044080	Glycine max	29.71	2.00e-58	219.00
IUUC-Ggo-045257	Gorilla gorilla	41.86	8.00e-102	362.00
IUUC-Hsa-046887	Homo sapiens	41.85	5.00e-100	356.00
IUUC-Hvu-047317	Hordeum vulgare	28.13	6.00e-47	180.00
IUUC-Itr-048199	Ictidomys tridecemlineatus	41.97	3.00e-101	360.00
IUUC-Lch-050155	Latimeria chalumnae	43.39	4.00e-106	376.00
IUUC-Lpe-051669	Leersia perrieri	30.16	1.00e-31	130.00
IUUC-Loc-051779	Lepisosteus oculatus	43.61	2.00e-104	370.00
IUUC-Lma-052969	Leptosphaeria maculans	22.85	5.00e-33	134.00
IUUC-Laf-053488	Loxodonta africana	42.24	6.00e-105	373.00
IUUC-Mcc-054701	Macaca mulatta	42.06	1.00e-100	358.00
IUUC-Meu-056577	Macropus eugenii	31.21	8.00e-34	136.00
IUUC-Mor-057157	Magnaporthe oryzae	22.29	2.00e-33	135.00
IUUC-Mpo-057518	Magnaporthe poae	23.01	2.00e-35	142.00
IUUC-Mtr-058125	Medicago truncatula	27.84	3.00e-49	188.00
IUUC-Mga-059906	Meleagris gallopavo	41.58	2.00e-103	368.00
IUUC-Mvi-060374	Microbotryum violaceum	30.47	1.00e-28	119.00
IUUC-Mmr-061786	Microcebus murinus	42.13	3.00e-101	360.00
IUUC-Mdo-062453	Monodelphis domestica	42.24	1.00e-103	368.00
IUUC-Mmu-063521	Mus musculus	41.74	1.00e-95	342.00
IUUC-Mac-065119	Musa acuminata	30.27	6.00e-48	183.00
IUUC-Mpu-066274	Mustela putorius furo	42.18	2.00e-101	361.00
IUUC-Mlu-067202	Myotis lucifugus	42.48	5.00e-97	346.00
IUUC-Nfi-068564	Neosartorya fischeri	24.36	2.00e-38	152.00
IUUC-Ncr-068823	Neurospora crassa	22.73	2.00e-32	132.00
IUUC-Nle-068987	Nomascus leucogenys	41.79	1.00e-100	358.00
IUUC-Opr-070453	Ochotona princeps	41.54	5.00e-100	356.00
IUUC-Ont-072611	Oreochromis niloticus	41.95	2.00e-109	387.00
IUUC-Oan-073738	Ornithorhynchus anatinus	41.21	1.00e-102	365.00
IUUC-Ocu-074396	Oryctolagus cuniculus	41.11	1.00e-98	352.00
IUUC-Oba-075472	Oryza barthii	28.73	4.00e-43	167.00
IUUC-Obr-076277	Oryza brachyantha	28.41	6.00e-48	184.00
IUUC-Ogl-077046	Oryza glaberrima	28.51	8.00e-42	163.00
IUUC-Ogu-078634	Oryza glumaepatula	28.73	3.00e-43	168.00
IUUC-Oin-080080	Oryza indica	28.27	4.00e-47	181.00
IUUC-Olo-080828	Oryza longistaminata	27.97	3.00e-45	176.00
IUUC-Ome-081387	Oryza meridionalis	27.67	5.00e-49	187.00
IUUC-Oni-082934	Oryza nivara	28.73	2.00e-43	169.00
IUUC-Opu-083719	Oryza punctata	28.53	7.00e-41	160.00
IUUC-Oru-084518	Oryza rufipogon	28.73	3.00e-43	168.00
IUUC-Ola-087312	Oryzias latipes	42.89	7.00e-104	369.00
IUUC-Olu-087661	Ostreococcus lucimarinus	34.21	1.00e-57	216.00
IUUC-Oga-089129	Otolemur garnettii	41.74	1.00e-100	358.00
IUUC-Oar-089839	Ovis aries	41.54	3.00e-100	357.00
IUUC-Ptr-091626	Pan troglodytes	42.06	1.00e-100	358.00
IUUC-Pan-092798	Papio anubis	42.06	1.00e-100	358.00
IUUC-Psi-093253	Pelodiscus sinensis	41.04	8.00e-104	369.00
IUUC-Pma-094512	Petromyzon marinus	40.13	2.00e-102	364.00
IUUC-Pno-094937	Phaeosphaeria nodorum	22.45	1.00e-32	132.00
IUUC-Ppa-095211	Physcomitrella patens	27.23	3.00e-48	185.00
IUUC-Pfo-097049	Poecilia formosa	38.68	9.00e-86	309.00
IUUC-Pab-097911	Pongo abelii	42.06	1.00e-100	358.00
IUUC-Pop-099841	Populus trichocarpa	30.02	5.00e-50	191.00
IUUC-Pca-100814	Procavia capensis	37.26	2.00e-70	258.00
IUUC-Ppe-101972	Prunus persica	28.78	2.00e-49	188.00
IUUC-Pva-103038	Pteropus vampyrus	41.11	2.00e-98	351.00
IUUC-Pgr-103277	Puccinia graminis	27.34	1.00e-38	152.00
IUUC-Ptt-103855	Puccinia triticina	26.17	7.00e-41	160.00
IUUC-Pte-104113	Pyrenophora teres	24.11	1.00e-32	132.00
IUUC-Pyt-104619	Pyrenophora triticirepentis	24.83	9.00e-33	133.00
IUUC-Rno-106003	Rattus norvegicus	40.31	2.00e-95	341.00
IUUC-Sce-106287	Saccharomyces cerevisiae	29.02	9.00e-23	99.80
IUUC-Sha-106652	Sarcophilus harrisii	42.22	2.00e-105	374.00
IUUC-Spo-108167	Schizosaccharomyces pombe	28.04	1.00e-42	165.00
IUUC-Smo-109393	Selaginella moellendorffii	30.75	2.00e-51	194.00
IUUC-Sit-110529	Setaria italica	28.60	4.00e-46	177.00
IUUC-Sly-111829	Solanum lycopersicum	30.14	2.00e-53	202.00
IUUC-Stu-112811	Solanum tuberosum	29.18	8.00e-53	200.00
IUUC-Sar-113259	Sorex araneus	36.75	2.00e-41	162.00
IUUC-Sbi-114591	Sorghum bicolor	30.63	2.00e-37	149.00
IUUC-Sre-115227	Sporisorium reilianum	25.78	6.00e-32	131.00
IUUC-Ssc-115293	Sus scrofa	41.97	1.00e-101	362.00
IUUC-Tgu-117335	Taeniopygia guttata	40.85	3.00e-105	373.00
IUUC-Tru-118458	Takifugu rubripes	42.09	1.00e-106	378.00
IUUC-Tsy-119475	Tarsius syrichta	39.29	2.00e-78	284.00
IUUC-Tni-119827	Tetraodon nigroviridis	41.70	5.00e-105	373.00
IUUC-Tca-121023	Theobroma cacao	31.29	2.00e-54	205.00
IUUC-Tre-121965	Trichoderma reesei	24.83	4.00e-38	150.00
IUUC-Tvi-122564	Trichoderma virens	23.00	4.00e-35	141.00
IUUC-Tae-124793	Triticum aestivum	28.67	2.00e-42	165.00
IUUC-Tur-126258	Triticum urartu	26.67	7.00e-44	170.00
IUUC-Tbe-127227	Tupaia belangeri	47.01	3.00e-32	131.00
IUUC-Ttr-128984	Tursiops truncatus	34.59	1.00e-73	269.00
IUUC-Uma-129565	Ustilago maydis	26.50	2.00e-33	135.00
IUUC-Vpa-130301	Vicugna pacos	42.18	6.00e-101	359.00
IUUC-Vvi-131244	Vitis vinifera	27.98	2.00e-51	196.00
IUUC-Xtr-132880	Xenopus tropicalis	40.35	3.00e-96	344.00
IUUC-Xma-134055	Xiphophorus maculatus	42.27	2.00e-105	374.00
IUUC-Yli-134342	Yarrowia lipolytica	28.31	9.00e-50	189.00
IUUC-Zma-135021	Zea mays	28.80	4.00e-43	168.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence