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Tag Content
UUCD2 ID IUUC-Aml-001997
UUCD1 version UUC-AiM-00720
Ensembl Protein ID ENSAMEP00000013812.1
UniProt Accession G1M3A0; G1M3A0_AILME
Genbank Protein ID ENSAMEP00000013812
Protein Name Ribosome biogenesis protein WDR12; WD repeat-containing protein 12
Genbank Nucleotide ID ACTA01128338
Gene Name WDR12
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSAMEG00000013091.1 ENSAMET00000014387.1 ENSAMEP00000013812.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 3.00e-43 144.0 341 376
UBD/Beta-Prp 5.00e-47 160.6 246 412
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWDlrtgv 34
           Ht++vt+l++  +    l+sGs D+ +k+WD+r+++
   Q: 341  HTGWVTSLKWspTHeQQLISGSLDNIVKLWDTRSCK 376
           **********9533678**************99876 PP
   

   UBD/Beta-Prp
   S: 83   tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl..ktg 169
           t+++++tl+gh++ v s+ +s   + + s+s+d tirvwd e+g+  + tl+g++ v nc++++p ++ l+sGs+Dr +rlWd   k g
   Q: 246  TRTPIVTLSGHKEAVSSVLWSD-AEEICSASWDHTIRVWDAESGSLKS-TLTGNK-VFNCISYSPLCKRLASGSTDRHIRLWDPrtKDG 331
           67899****************9.99**********************9.***987.99**************************54456 PP
   S: 170  kllrtl.tgghtdsvyslsfdsng.kelvsgsldgtvklwdlq.tgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW 249
           +l+    t+ ht+ v+sl+++++  ++l+sgsld+ vklwd +  +  ++ l +h+d v+sv+ + ++ +l+sg++D+ ++ +
   Q: 332  SLVSLSlTS-HTGWVTSLKWSPTHeQQLISGSLDNIVKLWDTRsCKAPLYDLAAHEDKVLSVDWT-DTGLLLSGGADNKLYSY 412
           666644366.************9889*****************54566****************9.999********998765 PP
   
Organism Ailuropoda melanoleuca
Functional Description
(View)

Functional Description


     Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
 Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
Protein Sequence
(Fasta)
ICRLDLDISF PFHRYAVDDV PFSIPAASEI ADLSNIINKL LEAKNEFHKH VEFDFLIKGQ 60
FLRMPLLKHM ELENISSEEV VELEYVEKYT APQPEQCMFH DDWISSVQGA EEWILTGSYD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Aml-001997|E3,WD_repeat;UBD,Beta-Prp|Ailuropoda melanoleuca
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATCTGTAGAC TTGACTTAGA CATATCATTT CCTTTTCACA GATACGCGGT AGATGATGTT 60
CCCTTCTCAA TTCCTGCAGC CTCGGAAATT GCCGACCTTA GTAACATCAT TAATAAATTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Aml-001997|E3,WD_repeat;UBD,Beta-Prp|Ailuropoda melanoleuca
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR012972--NLE
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR028599--WDR12/Ytm1
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF08154--NLE
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0030687--C:preribosome, large subunit precursor
GO:0043021--F:ribonucleoprotein complex binding
GO:0000466--P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000463--P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000532 Aegilops tauschii 34.16 4.00e-56 212.00
IUUC-Atr-002544 Amborella trichopoda 33.25 4.00e-54 205.00
IUUC-Apl-003981 Anas platyrhynchos 87.50 0.00e+00 647.00
IUUC-Aca-004370 Anolis carolinensis 84.22 0.00e+00 674.00
IUUC-Aly-006455 Arabidopsis lyrata 34.29 1.00e-57 217.00
IUUC-Ath-006669 Arabidopsis thaliana 33.49 4.00e-53 202.00
IUUC-Ago-007864 Ashbya gossypii 30.90 2.00e-35 143.00
IUUC-Acl-008177 Aspergillus clavatus 29.16 3.00e-35 142.00
IUUC-Afl-008617 Aspergillus flavus 29.23 4.00e-35 142.00
IUUC-Afu-008752 Aspergillus fumigatus 28.97 1.00e-31 130.00
IUUC-Ani-009136 Aspergillus nidulans 29.74 4.00e-34 139.00
IUUC-Ang-009701 Aspergillus niger 28.21 1.00e-32 134.00
IUUC-Aor-009884 Aspergillus oryzae 29.49 1.00e-34 140.00
IUUC-Ame-011432 Astyanax mexicanus 76.46 0.00e+00 634.00
IUUC-Bgr-012218 Blumeria graminis 28.57 4.00e-31 129.00
IUUC-Bta-012829 Bos taurus 96.83 0.00e+00 750.00
IUUC-Bci-013953 Botrytis cinerea 30.05 9.00e-34 137.00
IUUC-Bdi-014351 Brachypodium distachyon 37.06 1.00e-55 210.00
IUUC-Bol-016514 Brassica oleracea 33.66 3.00e-52 199.00
IUUC-Bra-017876 Brassica rapa 33.74 9.00e-55 207.00
IUUC-Cel-018569 Caenorhabditis elegans 32.75 2.00e-47 183.00
IUUC-Cja-019468 Callithrix jacchus 96.59 0.00e+00 729.00
IUUC-Cfa-020471 Canis familiaris 97.07 0.00e+00 725.00
IUUC-Cpo-022260 Cavia porcellus 96.10 0.00e+00 728.00
IUUC-Cre-022614 Chlamydomonas reinhardtii 30.83 6.00e-37 148.00
IUUC-Csa-023989 Chlorocebus sabaeus 96.59 0.00e+00 732.00
IUUC-Cho-024426 Choloepus hoffmanni 92.38 3.00e-158 551.00
IUUC-Cin-025789 Ciona intestinalis 43.07 1.00e-91 330.00
IUUC-Cne-027063 Cryptococcus neoformans 24.22 1.00e-19 91.30
IUUC-Dre-027907 Danio rerio 77.56 0.00e+00 644.00
IUUC-Dno-029225 Dasypus novemcinctus 95.37 0.00e+00 740.00
IUUC-Dor-031082 Dipodomys ordii 78.29 3.00e-161 561.00
IUUC-Dse-031308 Dothistroma septosporum 29.46 6.00e-35 141.00
IUUC-Dme-032189 Drosophila melanogaster 41.85 1.00e-89 323.00
IUUC-Ete-032247 Echinops telfairi 88.54 0.00e+00 680.00
IUUC-Eca-034285 Equus caballus 97.32 0.00e+00 752.00
IUUC-Eeu-035322 Erinaceus europaeus 85.71 1.00e-179 622.00
IUUC-Fca-036114 Felis catus 97.80 0.00e+00 752.00
IUUC-Fal-036891 Ficedula albicollis 86.72 7.00e-174 602.00
IUUC-Fox-037965 Fusarium oxysporum 26.13 8.00e-33 134.00
IUUC-Fso-038244 Fusarium solani 27.59 3.00e-33 136.00
IUUC-Gmo-039040 Gadus morhua 75.85 0.00e+00 646.00
IUUC-Gga-040610 Gallus gallus 85.37 0.00e+00 696.00
IUUC-Gac-042117 Gasterosteus aculeatus 75.61 0.00e+00 627.00
IUUC-Gma-043146 Glycine max 36.88 6.00e-63 234.00
IUUC-Ggo-045179 Gorilla gorilla 96.10 0.00e+00 723.00
IUUC-Hsa-046114 Homo sapiens 96.83 0.00e+00 729.00
IUUC-Hvu-047331 Hordeum vulgare 34.10 3.00e-52 199.00
IUUC-Itr-048275 Ictidomys tridecemlineatus 95.85 0.00e+00 742.00
IUUC-Kpa-049304 Komagataella pastoris 29.72 2.00e-39 156.00
IUUC-Lch-050655 Latimeria chalumnae 78.88 2.00e-138 484.00
IUUC-Lpe-051675 Leersia perrieri 35.84 5.00e-57 215.00
IUUC-Loc-052868 Lepisosteus oculatus 80.98 0.00e+00 646.00
IUUC-Lma-053258 Leptosphaeria maculans 28.34 5.00e-30 127.00
IUUC-Laf-053993 Loxodonta africana 95.61 0.00e+00 745.00
IUUC-Mcc-055128 Macaca mulatta 78.78 1.00e-164 572.00
IUUC-Meu-056501 Macropus eugenii 86.20 1.00e-157 548.00
IUUC-Mor-057114 Magnaporthe oryzae 25.94 1.00e-24 107.00
IUUC-Mtr-058367 Medicago truncatula 36.21 5.00e-57 214.00
IUUC-Mla-059107 Melampsora laricipopulina 27.37 6.00e-27 115.00
IUUC-Mga-059745 Meleagris gallopavo 84.67 0.00e+00 684.00
IUUC-Mvi-060362 Microbotryum violaceum 29.39 3.00e-32 132.00
IUUC-Mdo-062257 Monodelphis domestica 85.47 0.00e+00 693.00
IUUC-Mmu-063546 Mus musculus 94.15 0.00e+00 736.00
IUUC-Mac-065540 Musa acuminata 34.47 1.00e-53 203.00
IUUC-Mpu-066284 Mustela putorius furo 98.78 0.00e+00 760.00
IUUC-Mlu-067241 Myotis lucifugus 95.85 0.00e+00 745.00
IUUC-Nfi-068260 Neosartorya fischeri 28.21 2.00e-33 136.00
IUUC-Ncr-068719 Neurospora crassa 27.27 2.00e-25 110.00
IUUC-Nle-068981 Nomascus leucogenys 96.59 0.00e+00 708.00
IUUC-Opr-071218 Ochotona princeps 88.05 0.00e+00 646.00
IUUC-Ont-071646 Oreochromis niloticus 78.36 0.00e+00 649.00
IUUC-Oan-073453 Ornithorhynchus anatinus 89.51 0.00e+00 733.00
IUUC-Ocu-074008 Oryctolagus cuniculus 97.56 0.00e+00 753.00
IUUC-Oba-075712 Oryza barthii 31.31 3.00e-40 159.00
IUUC-Obr-076721 Oryza brachyantha 35.25 1.00e-56 214.00
IUUC-Ogl-077229 Oryza glaberrima 35.34 5.00e-56 211.00
IUUC-Ogu-078977 Oryza glumaepatula 31.31 1.00e-40 160.00
IUUC-Oin-079683 Oryza indica 35.34 4.00e-56 212.00
IUUC-Olo-080291 Oryza longistaminata 30.98 6.00e-28 117.00
IUUC-Ome-081834 Oryza meridionalis 35.59 4.00e-57 215.00
IUUC-Oni-082507 Oryza nivara 34.17 3.00e-52 199.00
IUUC-Opu-083396 Oryza punctata 35.59 3.00e-57 216.00
IUUC-Oru-085220 Oryza rufipogon 34.17 6.00e-52 197.00
IUUC-Osa-085767 Oryza sativa 35.34 4.00e-56 212.00
IUUC-Ola-087420 Oryzias latipes 78.05 0.00e+00 647.00
IUUC-Olu-087740 Ostreococcus lucimarinus 27.74 5.00e-35 142.00
IUUC-Oga-088264 Otolemur garnettii 95.37 0.00e+00 724.00
IUUC-Oar-089335 Ovis aries 96.34 0.00e+00 747.00
IUUC-Ptr-091320 Pan troglodytes 96.83 0.00e+00 729.00
IUUC-Pan-092833 Papio anubis 96.10 0.00e+00 727.00
IUUC-Psi-093504 Pelodiscus sinensis 87.32 0.00e+00 708.00
IUUC-Pma-094189 Petromyzon marinus 69.10 9.00e-165 572.00
IUUC-Pno-094929 Phaeosphaeria nodorum 28.34 6.00e-32 131.00
IUUC-Ppa-095429 Physcomitrella patens 35.64 8.00e-63 234.00
IUUC-Pfo-096337 Poecilia formosa 76.16 0.00e+00 652.00
IUUC-Pab-097571 Pongo abelii 96.34 0.00e+00 728.00
IUUC-Pop-099977 Populus trichocarpa 35.24 2.00e-60 226.00
IUUC-Pca-100394 Procavia capensis 89.73 0.00e+00 671.00
IUUC-Ppe-101848 Prunus persica 36.61 2.00e-59 223.00
IUUC-Pva-102921 Pteropus vampyrus 96.15 8.00e-108 383.00
IUUC-Pgr-103637 Puccinia graminis 28.35 2.00e-32 133.00
IUUC-Ptt-103781 Puccinia triticina 28.35 3.00e-32 132.00
IUUC-Pte-104135 Pyrenophora teres 26.54 3.00e-32 134.00
IUUC-Pyt-104609 Pyrenophora triticirepentis 27.42 9.00e-31 127.00
IUUC-Rno-105114 Rattus norvegicus 93.17 0.00e+00 730.00
IUUC-Sce-106401 Saccharomyces cerevisiae 30.21 1.00e-36 147.00
IUUC-Sha-107122 Sarcophilus harrisii 85.93 0.00e+00 665.00
IUUC-Sja-107766 Schizosaccharomyces japonicus 31.64 2.00e-43 170.00
IUUC-Spo-108134 Schizosaccharomyces pombe 28.91 2.00e-34 140.00
IUUC-Ssl-108398 Sclerotinia sclerotiorum 29.27 1.00e-34 140.00
IUUC-Smo-108720 Selaginella moellendorffii 33.09 2.00e-54 206.00
IUUC-Sit-110311 Setaria italica 35.81 2.00e-55 209.00
IUUC-Sly-111023 Solanum lycopersicum 32.64 6.00e-51 194.00
IUUC-Stu-112778 Solanum tuberosum 35.84 2.00e-57 216.00
IUUC-Sar-113596 Sorex araneus 84.88 5.00e-170 590.00
IUUC-Sbi-114193 Sorghum bicolor 35.48 1.00e-56 213.00
IUUC-Sre-115002 Sporisorium reilianum 25.00 6.00e-11 62.40
IUUC-Ssc-116066 Sus scrofa 97.07 0.00e+00 749.00
IUUC-Tgu-117048 Taeniopygia guttata 85.37 0.00e+00 639.00
IUUC-Tsy-119573 Tarsius syrichta 62.62 2.00e-128 451.00
IUUC-Tni-119820 Tetraodon nigroviridis 76.72 0.00e+00 649.00
IUUC-Tca-121605 Theobroma cacao 35.73 1.00e-58 220.00
IUUC-Tre-121947 Trichoderma reesei 26.80 8.00e-32 131.00
IUUC-Tvi-122481 Trichoderma virens 27.03 2.00e-33 136.00
IUUC-Tae-125861 Triticum aestivum 34.41 4.00e-56 212.00
IUUC-Tur-126586 Triticum urartu 34.36 2.00e-54 206.00
IUUC-Tme-126900 Tuber melanosporum 32.93 5.00e-46 178.00
IUUC-Tbe-127736 Tupaia belangeri 72.47 6.00e-145 506.00
IUUC-Ttr-129041 Tursiops truncatus 84.63 0.00e+00 638.00
IUUC-Uma-129628 Ustilago maydis 36.84 2.00e-06 47.40
IUUC-Vpa-130260 Vicugna pacos 97.32 0.00e+00 753.00
IUUC-Vvi-131009 Vitis vinifera 36.00 5.00e-58 218.00
IUUC-Xtr-132083 Xenopus tropicalis 81.22 0.00e+00 651.00
IUUC-Xma-133094 Xiphophorus maculatus 75.43 0.00e+00 645.00
IUUC-Yli-134531 Yarrowia lipolytica 23.66 4.00e-19 89.40
IUUC-Zma-135509 Zea mays 34.50 1.00e-56 213.00
Created Date 25-Jun-2017

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