iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-060188

UUCD1 version

UUC-MeG-00281

Ensembl Protein ID

ENSMGAP00000005776.1

UniProt Accession

G1N2C7; G1N2C7_MELGA

Protein Name

Uncharacterized protein

Gene Name

MUL1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000005830.1	ENSMGAT00000006519.1	ENSMGAP00000005776.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	73.08	4.00e-143	505.00	IUUC-Hsa-046597

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

GARRLRLDGE LRAVLLEAPG RCVPYAVIEG VVRTVKDTLS SQFVENCKGV VQRLTLQEHK 60
MVWNRTTHLW NDYEKIIHQR TNTTAFDLAP LEDGAGVAVR VMKPLEAAEL SLETVHEKFH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGCCCGGA GGCTGCGGCT GGACGGGGAG CTGCGGGCCG TGCTGCTGGA GGCGCCGGGC 60
CGCTGCGTGC CCTATGCTGT CATCGAAGGT ATTGGCATGG CAAAACCCTG GGCCTCTTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR022170--GIDE
IPR001841--Znf_RING

PROSITE

PS50089--ZF_RING_2

Pfam

PF12483--GIDE

SMART

SM00184--RING

Gene Ontology

GO:0030424--C:axon
GO:0031307--C:integral component of mitochondrial outer membrane
GO:0043025--C:neuronal cell body
GO:0005777--C:peroxisome
GO:0004871--F:signal transducer activity
GO:0019789--F:SUMO transferase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007257--P:activation of JUN kinase activity
GO:0071360--P:cellular response to exogenous dsRNA
GO:0000266--P:mitochondrial fission
GO:0051646--P:mitochondrion localization
GO:0030308--P:negative regulation of cell growth
GO:0071650--P:negative regulation of chemokine (C-C motif) ligand 5 production
GO:0050689--P:negative regulation of defense response to virus by host
GO:0010637--P:negative regulation of mitochondrial fusion
GO:0051898--P:negative regulation of protein kinase B signaling
GO:0060339--P:negative regulation of type I interferon-mediated signaling pathway
GO:1903861--P:positive regulation of dendrite extension
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0090141--P:positive regulation of mitochondrial fission
GO:1904925--P:positive regulation of mitophagy in response to mitochondrial depolarization
GO:0033235--P:positive regulation of protein sumoylation
GO:0031648--P:protein destabilization
GO:0050821--P:protein stabilization
GO:0051881--P:regulation of mitochondrial membrane potential
GO:1901028--P:regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000342	Aegilops tauschii	25.00	1.00e-11	64.70
IUUC-Aml-002287	Ailuropoda melanoleuca	72.76	6.00e-138	483.00
IUUC-Atr-002698	Amborella trichopoda	27.69	2.00e-11	62.80
IUUC-Aca-005039	Anolis carolinensis	41.21	1.00e-59	222.00
IUUC-Aly-006181	Arabidopsis lyrata	25.79	2.00e-17	82.80
IUUC-Ath-007438	Arabidopsis thaliana	26.42	9.00e-19	87.00
IUUC-Ame-010671	Astyanax mexicanus	60.45	2.00e-121	428.00
IUUC-Bta-012407	Bos taurus	67.09	7.00e-124	436.00
IUUC-Bdi-014735	Brachypodium distachyon	29.32	3.00e-16	79.00
IUUC-Bol-015493	Brassica oleracea	25.91	5.00e-20	91.30
IUUC-Bra-016933	Brassica rapa	25.72	5.00e-19	88.20
IUUC-Cja-019709	Callithrix jacchus	73.40	2.00e-145	507.00
IUUC-Cfa-020818	Canis familiaris	73.08	1.00e-141	495.00
IUUC-Cpo-022490	Cavia porcellus	72.76	4.00e-133	466.00
IUUC-Csa-023259	Chlorocebus sabaeus	73.08	1.00e-144	505.00
IUUC-Cho-024730	Choloepus hoffmanni	73.72	3.00e-144	503.00
IUUC-Cin-025301	Ciona intestinalis	33.65	4.00e-47	181.00
IUUC-Dre-028644	Danio rerio	61.74	3.00e-122	431.00
IUUC-Dno-028925	Dasypus novemcinctus	73.72	7.00e-146	509.00
IUUC-Dor-030692	Dipodomys ordii	71.79	1.00e-136	478.00
IUUC-Dme-031761	Drosophila melanogaster	30.82	3.00e-30	125.00
IUUC-Ete-032329	Echinops telfairi	73.31	6.00e-119	419.00
IUUC-Eca-034008	Equus caballus	72.76	2.00e-141	494.00
IUUC-Eeu-034895	Erinaceus europaeus	67.31	4.00e-105	373.00
IUUC-Fca-036104	Felis catus	71.15	4.00e-138	483.00
IUUC-Fal-036900	Ficedula albicollis	83.71	3.00e-143	500.00
IUUC-Gmo-039049	Gadus morhua	57.88	2.00e-93	335.00
IUUC-Gga-040254	Gallus gallus	95.41	2.00e-177	614.00
IUUC-Gac-042277	Gasterosteus aculeatus	62.18	3.00e-125	441.00
IUUC-Gma-043979	Glycine max	25.17	2.00e-16	79.30
IUUC-Ggo-045509	Gorilla gorilla	73.08	1.00e-144	505.00
IUUC-Hsa-046597	Homo sapiens	73.08	1.00e-144	505.00
IUUC-Hvu-047335	Hordeum vulgare	26.64	2.00e-19	89.40
IUUC-Itr-048691	Ictidomys tridecemlineatus	72.44	3.00e-135	474.00
IUUC-Lch-050344	Latimeria chalumnae	67.20	1.00e-127	448.00
IUUC-Lpe-051343	Leersia perrieri	25.99	4.00e-12	65.10
IUUC-Loc-052376	Lepisosteus oculatus	65.92	8.00e-134	469.00
IUUC-Laf-054414	Loxodonta africana	74.36	2.00e-146	511.00
IUUC-Mcc-054604	Macaca mulatta	73.08	2.00e-144	504.00
IUUC-Meu-056087	Macropus eugenii	76.60	6.00e-144	503.00
IUUC-Mtr-057779	Medicago truncatula	26.71	1.00e-16	80.50
IUUC-Mmr-060704	Microcebus murinus	74.36	6.00e-146	509.00
IUUC-Mdo-062842	Monodelphis domestica	76.92	2.00e-138	484.00
IUUC-Mmu-064324	Mus musculus	71.15	1.00e-133	469.00
IUUC-Mpu-065940	Mustela putorius furo	71.15	6.00e-134	469.00
IUUC-Mlu-067028	Myotis lucifugus	71.79	4.00e-144	503.00
IUUC-Nle-069254	Nomascus leucogenys	66.56	1.00e-129	455.00
IUUC-Opr-070827	Ochotona princeps	70.51	5.00e-139	486.00
IUUC-Ont-072008	Oreochromis niloticus	62.06	1.00e-123	435.00
IUUC-Oan-072935	Ornithorhynchus anatinus	71.15	3.00e-135	474.00
IUUC-Ocu-074526	Oryctolagus cuniculus	73.40	1.00e-133	468.00
IUUC-Oba-075954	Oryza barthii	24.28	8.00e-13	67.40
IUUC-Obr-076592	Oryza brachyantha	25.64	6.00e-21	94.40
IUUC-Ogl-077732	Oryza glaberrima	25.96	1.00e-21	96.70
IUUC-Ogu-078565	Oryza glumaepatula	24.55	2.00e-13	69.30
IUUC-Oin-080188	Oryza indica	25.96	1.00e-21	96.70
IUUC-Olo-080705	Oryza longistaminata	26.94	8.00e-17	81.30
IUUC-Ome-081154	Oryza meridionalis	24.55	1.00e-13	70.50
IUUC-Oni-082201	Oryza nivara	24.28	8.00e-13	67.40
IUUC-Opu-083497	Oryza punctata	24.55	2.00e-13	69.70
IUUC-Oru-084332	Oryza rufipogon	24.28	8.00e-13	67.40
IUUC-Osa-086059	Oryza sativa	25.99	2.00e-12	65.90
IUUC-Ola-087288	Oryzias latipes	61.09	3.00e-114	404.00
IUUC-Oga-088402	Otolemur garnettii	73.40	5.00e-145	506.00
IUUC-Oar-089851	Ovis aries	75.41	1.00e-54	204.00
IUUC-Ptr-091226	Pan troglodytes	73.08	2.00e-144	504.00
IUUC-Pan-092575	Papio anubis	72.76	4.00e-144	503.00
IUUC-Psi-094062	Pelodiscus sinensis	78.53	4.00e-150	523.00
IUUC-Pma-094501	Petromyzon marinus	38.66	1.00e-39	156.00
IUUC-Ppa-095285	Physcomitrella patens	22.87	9.00e-10	57.40
IUUC-Pfo-096146	Poecilia formosa	57.88	3.00e-108	384.00
IUUC-Pab-098524	Pongo abelii	73.08	2.00e-144	504.00
IUUC-Pop-099864	Populus trichocarpa	25.70	2.00e-17	82.40
IUUC-Pca-100314	Procavia capensis	74.04	4.00e-146	510.00
IUUC-Ppe-101663	Prunus persica	25.45	4.00e-15	75.10
IUUC-Pva-102947	Pteropus vampyrus	72.44	4.00e-142	496.00
IUUC-Rno-105024	Rattus norvegicus	70.51	6.00e-134	469.00
IUUC-Sha-107500	Sarcophilus harrisii	64.10	2.00e-107	381.00
IUUC-Smo-109194	Selaginella moellendorffii	26.50	4.00e-19	88.20
IUUC-Sit-109922	Setaria italica	28.97	1.00e-19	90.10
IUUC-Sly-111826	Solanum lycopersicum	27.56	3.00e-19	88.60
IUUC-Stu-112907	Solanum tuberosum	27.80	2.00e-18	86.30
IUUC-Sar-113522	Sorex araneus	71.15	4.00e-136	476.00
IUUC-Sbi-114536	Sorghum bicolor	26.60	5.00e-23	101.00
IUUC-Ssc-115445	Sus scrofa	73.08	5.00e-133	466.00
IUUC-Tgu-116551	Taeniopygia guttata	83.33	3.00e-144	503.00
IUUC-Tru-118407	Takifugu rubripes	60.77	2.00e-109	387.00
IUUC-Tsy-118794	Tarsius syrichta	71.47	4.00e-138	483.00
IUUC-Tni-120128	Tetraodon nigroviridis	64.80	1.00e-77	282.00
IUUC-Tca-121508	Theobroma cacao	26.58	5.00e-19	88.20
IUUC-Tae-125185	Triticum aestivum	26.05	6.00e-20	91.30
IUUC-Tur-126470	Triticum urartu	25.72	8.00e-20	90.50
IUUC-Tbe-127432	Tupaia belangeri	72.44	1.00e-131	462.00
IUUC-Ttr-128573	Tursiops truncatus	73.08	5.00e-138	483.00
IUUC-Vpa-130583	Vicugna pacos	72.12	2.00e-141	494.00
IUUC-Vvi-131710	Vitis vinifera	24.72	5.00e-17	81.30
IUUC-Xtr-132009	Xenopus tropicalis	61.34	4.00e-119	420.00
IUUC-Xma-134121	Xiphophorus maculatus	57.88	2.00e-114	404.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence