iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Csv-026128

UUCD1 version

UUC-CiS-00205

Ensembl Protein ID

ENSCSAVP00000003406.1

UniProt Accession

H2YDK8; H2YDK8_CIOSA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAVG00000002027.1	ENSCSAVT00000003457.1	ENSCSAVP00000003405.1
ENSCSAVG00000002027.1	ENSCSAVT00000003458.1	ENSCSAVP00000003406.1
ENSCSAVG00000002027.1	ENSCSAVT00000003459.1	ENSCSAVP00000003407.1
ENSCSAVG00000002027.1	ENSCSAVT00000003460.1	ENSCSAVP00000003408.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	4.80e-06	26.5	7	57
E3 adaptor/Cullin RING/DCX/DWD	6.70e-28	95.6	406	439
UBD/Beta-Prp	3.00e-50	171.1	366	520

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 10   IslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnlt 60
           +s+e+++  +++p sG +++++ +ek++ ++g+ +P+++qpl+ e+++  +t
   Q: 7    VSGEVPEVACISPvSGCVFEKRLLEKFVFENGT-DPTNNQPLSMEQVIEMKT 57
           699*****************************9.***********9987665 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrt 32
           gH+++vt+++f  ++ +l+++++D  +k+WDlr+
   Q: 406  GHSGPVTAISFseNGYYLATAAGDACVKLWDLRK 439
           8**********976699**************986 PP

UBD/Beta-Prp

   S: 10   ksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk.gheds 96
           k  +tc +f+pd+ ++ tg +d+ i +wd+++ + ++ + gh+++vta++fs++g +l+t++ D+ +k+wdl++ k + tl+ + +++
   Q: 366  KYSLTCAQFHPDGLIFGTGTKDSQIMIWDLKERTNVANFPGHSGPVTAISFSENGYYLATAAGDACVKLWDLRKLKNFKTLTmADDYE 453
           5679******************************************************************************888899 PP
   S: 97   vlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl 166
           v+sl+f++sg++l++G+ d  +rv+  ++ q+l+  +s h++v ++v++ ++++ l+s+s Dr ++++++
   Q: 454  VRSLTFDQSGSYLAVGGTD--VRVYLCKQWQELK-AFSDHTAVATGVRFGKNAKFLASSSMDRSLKFFSI 520
           *****************77..999999999***9.*******************************9975 PP

Organism

Ciona savignyi

Protein Sequence
(Fasta)

ISLHILVSGE VPEVACISPV SGCVFEKRLL EKFVFENGTD PTNNQPLSME QVIEMKTNPI 60
VRPKPPSATS IPAILKSLQD EWDACMLTSF TLRQQLHTTR QELSHALYQH DAACRVIARL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAAACTGCT ATATATGTTT TTATTTTTAG GACATTTTTA AATCCTGCCT TTTTCTGAGA 60
TTATAAAACA TAAATATGTC TCTGGTTTGC TCAAGTAAGT ATTTTTATTT GTTTATTATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR013915--Pre-mRNA_splic_Prp19
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08606--Prp19
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000488	Aegilops tauschii	42.14	1.00e-104	373.00
IUUC-Aml-001230	Ailuropoda melanoleuca	64.08	0.00e+00	657.00
IUUC-Atr-002594	Amborella trichopoda	42.48	3.00e-117	414.00
IUUC-Apl-003686	Anas platyrhynchos	58.31	3.00e-146	509.00
IUUC-Aca-005272	Anolis carolinensis	65.38	0.00e+00	691.00
IUUC-Aly-005586	Arabidopsis lyrata	42.75	5.00e-120	422.00
IUUC-Ath-007693	Arabidopsis thaliana	42.01	1.00e-119	421.00
IUUC-Acl-008335	Aspergillus clavatus	34.30	6.00e-64	236.00
IUUC-Afl-008527	Aspergillus flavus	35.74	2.00e-69	254.00
IUUC-Afu-008957	Aspergillus fumigatus	35.21	2.00e-71	261.00
IUUC-Ani-009280	Aspergillus nidulans	36.78	9.00e-63	232.00
IUUC-Ang-009746	Aspergillus niger	35.27	1.00e-65	242.00
IUUC-Aor-009905	Aspergillus oryzae	35.74	5.00e-73	266.00
IUUC-Ate-010412	Aspergillus terreus	36.48	5.00e-63	233.00
IUUC-Ame-011561	Astyanax mexicanus	62.40	2.00e-80	290.00
IUUC-Bgr-012283	Blumeria graminis	30.20	2.00e-50	191.00
IUUC-Bta-013242	Bos taurus	65.19	0.00e+00	694.00
IUUC-Bci-013901	Botrytis cinerea	33.33	7.00e-63	233.00
IUUC-Bdi-014277	Brachypodium distachyon	43.54	4.00e-122	429.00
IUUC-Bol-016457	Brassica oleracea	43.40	3.00e-121	427.00
IUUC-Bra-017650	Brassica rapa	43.29	2.00e-120	424.00
IUUC-Cel-018271	Caenorhabditis elegans	48.16	1.00e-143	501.00
IUUC-Cja-019879	Callithrix jacchus	65.52	0.00e+00	692.00
IUUC-Cfa-020175	Canis familiaris	65.00	0.00e+00	692.00
IUUC-Cpo-022379	Cavia porcellus	65.38	0.00e+00	694.00
IUUC-Cre-022993	Chlamydomonas reinhardtii	40.66	7.00e-102	362.00
IUUC-Csa-023500	Chlorocebus sabaeus	65.38	0.00e+00	696.00
IUUC-Cho-025065	Choloepus hoffmanni	54.01	5.00e-89	318.00
IUUC-Cin-025699	Ciona intestinalis	85.43	0.00e+00	741.00
IUUC-Cgl-026507	Colletotrichum gloeosporioides	34.17	5.00e-62	229.00
IUUC-Cne-026860	Cryptococcus neoformans	37.24	7.00e-97	345.00
IUUC-Dre-028187	Danio rerio	65.77	0.00e+00	693.00
IUUC-Dno-029453	Dasypus novemcinctus	65.38	0.00e+00	695.00
IUUC-Dor-030150	Dipodomys ordii	60.96	3.00e-80	290.00
IUUC-Dse-031220	Dothistroma septosporum	30.86	9.00e-58	216.00
IUUC-Dme-031906	Drosophila melanogaster	61.19	0.00e+00	634.00
IUUC-Ete-033035	Echinops telfairi	69.26	3.00e-100	357.00
IUUC-Eca-033478	Equus caballus	65.19	0.00e+00	694.00
IUUC-Eeu-034974	Erinaceus europaeus	68.07	2.00e-143	501.00
IUUC-Fca-036194	Felis catus	65.56	0.00e+00	693.00
IUUC-Fal-037417	Ficedula albicollis	65.37	0.00e+00	687.00
IUUC-Fox-037922	Fusarium oxysporum	33.00	1.00e-61	228.00
IUUC-Fso-038256	Fusarium solani	34.12	7.00e-67	246.00
IUUC-Gmo-038713	Gadus morhua	67.69	0.00e+00	717.00
IUUC-Ggr-039854	Gaeumannomyces graminis	30.80	3.00e-49	187.00
IUUC-Gga-041143	Gallus gallus	64.98	0.00e+00	688.00
IUUC-Gac-042129	Gasterosteus aculeatus	65.96	0.00e+00	706.00
IUUC-Gma-043635	Glycine max	43.94	1.00e-120	424.00
IUUC-Ggo-045262	Gorilla gorilla	65.38	0.00e+00	696.00
IUUC-Hsa-046036	Homo sapiens	65.38	0.00e+00	696.00
IUUC-Hvu-047442	Hordeum vulgare	40.62	2.00e-65	240.00
IUUC-Itr-048169	Ictidomys tridecemlineatus	65.58	0.00e+00	688.00
IUUC-Lch-050105	Latimeria chalumnae	66.15	0.00e+00	689.00
IUUC-Lpe-050976	Leersia perrieri	44.66	8.00e-122	429.00
IUUC-Loc-052042	Lepisosteus oculatus	59.50	9.00e-149	518.00
IUUC-Lma-053143	Leptosphaeria maculans	33.08	3.00e-62	232.00
IUUC-Laf-053451	Loxodonta africana	62.94	0.00e+00	683.00
IUUC-Mcc-055786	Macaca mulatta	65.38	0.00e+00	696.00
IUUC-Meu-056161	Macropus eugenii	67.08	2.00e-99	354.00
IUUC-Mor-057215	Magnaporthe oryzae	31.12	1.00e-51	195.00
IUUC-Mpo-057419	Magnaporthe poae	29.57	2.00e-47	182.00
IUUC-Mtr-057756	Medicago truncatula	45.52	3.00e-121	427.00
IUUC-Mla-059085	Melampsora laricipopulina	36.31	9.00e-85	305.00
IUUC-Mga-060158	Meleagris gallopavo	63.27	6.00e-180	622.00
IUUC-Mvi-060441	Microbotryum violaceum	36.07	3.00e-72	264.00
IUUC-Mmr-061085	Microcebus murinus	65.38	0.00e+00	696.00
IUUC-Mdo-061804	Monodelphis domestica	65.38	0.00e+00	697.00
IUUC-Mmu-063608	Mus musculus	62.71	0.00e+00	681.00
IUUC-Mac-064972	Musa acuminata	43.64	9.00e-117	412.00
IUUC-Mpu-065700	Mustela putorius furo	65.00	0.00e+00	693.00
IUUC-Mlu-068223	Myotis lucifugus	62.43	0.00e+00	681.00
IUUC-Nfi-068504	Neosartorya fischeri	34.41	2.00e-70	258.00
IUUC-Ncr-068729	Neurospora crassa	33.98	7.00e-63	233.00
IUUC-Nle-069754	Nomascus leucogenys	65.38	0.00e+00	696.00
IUUC-Opr-070621	Ochotona princeps	63.74	0.00e+00	662.00
IUUC-Ont-071377	Oreochromis niloticus	66.35	0.00e+00	709.00
IUUC-Oan-073498	Ornithorhynchus anatinus	62.22	6.00e-66	242.00
IUUC-Ocu-074182	Oryctolagus cuniculus	62.85	0.00e+00	684.00
IUUC-Oba-075509	Oryza barthii	43.89	7.00e-120	422.00
IUUC-Obr-076480	Oryza brachyantha	44.47	8.00e-122	429.00
IUUC-Ogl-077052	Oryza glaberrima	43.89	6.00e-120	422.00
IUUC-Ogu-078919	Oryza glumaepatula	44.08	2.00e-120	424.00
IUUC-Oin-079357	Oryza indica	42.80	4.00e-113	399.00
IUUC-Olo-080376	Oryza longistaminata	44.04	9.00e-112	395.00
IUUC-Ome-081973	Oryza meridionalis	43.84	6.00e-111	392.00
IUUC-Oni-082849	Oryza nivara	43.89	3.00e-120	423.00
IUUC-Opu-083243	Oryza punctata	43.70	5.00e-120	422.00
IUUC-Oru-084613	Oryza rufipogon	43.89	6.00e-120	422.00
IUUC-Osa-085407	Oryza sativa	44.06	7.00e-120	422.00
IUUC-Ola-086566	Oryzias latipes	65.90	0.00e+00	704.00
IUUC-Olu-087757	Ostreococcus lucimarinus	37.82	2.00e-90	324.00
IUUC-Oga-089010	Otolemur garnettii	64.93	0.00e+00	676.00
IUUC-Oar-089638	Ovis aries	65.19	0.00e+00	694.00
IUUC-Ptr-091141	Pan troglodytes	65.38	0.00e+00	696.00
IUUC-Pan-092662	Papio anubis	65.38	0.00e+00	696.00
IUUC-Psi-093777	Pelodiscus sinensis	64.83	1.00e-165	573.00
IUUC-Pno-095115	Phaeosphaeria nodorum	33.54	5.00e-60	223.00
IUUC-Ppa-095841	Physcomitrella patens	44.83	2.00e-122	431.00
IUUC-Pfo-096390	Poecilia formosa	66.15	0.00e+00	705.00
IUUC-Pab-098250	Pongo abelii	65.64	0.00e+00	651.00
IUUC-Pop-099854	Populus trichocarpa	44.26	9.00e-123	432.00
IUUC-Pca-100553	Procavia capensis	65.00	0.00e+00	687.00
IUUC-Ppe-101383	Prunus persica	44.21	1.00e-115	408.00
IUUC-Pva-102189	Pteropus vampyrus	65.00	0.00e+00	693.00
IUUC-Pgr-103304	Puccinia graminis	34.57	1.00e-81	295.00
IUUC-Ptt-103984	Puccinia triticina	34.70	7.00e-85	306.00
IUUC-Pte-104385	Pyrenophora teres	33.20	8.00e-62	229.00
IUUC-Pyt-104697	Pyrenophora triticirepentis	33.47	1.00e-61	229.00
IUUC-Rno-105581	Rattus norvegicus	65.00	0.00e+00	692.00
IUUC-Sha-107071	Sarcophilus harrisii	62.55	0.00e+00	683.00
IUUC-Sja-107697	Schizosaccharomyces japonicus	30.69	1.00e-27	115.00
IUUC-Spo-108315	Schizosaccharomyces pombe	30.02	4.00e-37	147.00
IUUC-Ssl-108628	Sclerotinia sclerotiorum	33.53	1.00e-62	232.00
IUUC-Smo-109648	Selaginella moellendorffii	42.72	8.00e-116	409.00
IUUC-Sit-109873	Setaria italica	43.51	3.00e-120	424.00
IUUC-Sly-111673	Solanum lycopersicum	44.76	2.00e-114	404.00
IUUC-Stu-112125	Solanum tuberosum	44.19	2.00e-113	400.00
IUUC-Sbi-114696	Sorghum bicolor	41.89	2.00e-107	381.00
IUUC-Sre-115134	Sporisorium reilianum	32.60	1.00e-74	272.00
IUUC-Ssc-116260	Sus scrofa	65.38	0.00e+00	696.00
IUUC-Tgu-116533	Taeniopygia guttata	65.37	0.00e+00	687.00
IUUC-Tru-117800	Takifugu rubripes	66.35	0.00e+00	706.00
IUUC-Tsy-118980	Tarsius syrichta	62.25	0.00e+00	632.00
IUUC-Tni-120334	Tetraodon nigroviridis	67.13	5.00e-149	518.00
IUUC-Tca-121807	Theobroma cacao	43.32	4.00e-120	423.00
IUUC-Tre-121920	Trichoderma reesei	33.27	1.00e-63	235.00
IUUC-Tvi-122294	Trichoderma virens	31.37	1.00e-49	189.00
IUUC-Tae-125794	Triticum aestivum	44.11	1.00e-122	432.00
IUUC-Tur-126664	Triticum urartu	41.05	1.00e-116	412.00
IUUC-Tme-127026	Tuber melanosporum	34.42	2.00e-71	261.00
IUUC-Tbe-127582	Tupaia belangeri	68.37	4.00e-144	503.00
IUUC-Ttr-128313	Tursiops truncatus	64.81	0.00e+00	684.00
IUUC-Uma-129626	Ustilago maydis	32.35	1.00e-72	265.00
IUUC-Vda-129699	Verticillium dahliae	32.96	2.00e-62	231.00
IUUC-Vpa-130593	Vicugna pacos	65.74	0.00e+00	629.00
IUUC-Vvi-131668	Vitis vinifera	45.08	1.00e-123	435.00
IUUC-Xtr-132186	Xenopus tropicalis	64.62	7.00e-169	585.00
IUUC-Xma-133212	Xiphophorus maculatus	65.96	0.00e+00	700.00
IUUC-Yli-134607	Yarrowia lipolytica	53.91	1.00e-36	143.00
IUUC-Zma-135662	Zea mays	43.70	4.00e-121	426.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence