iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Post-translational Modifications (PTMs)
dbPAF	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/ULP	2.10e-43	148.6	1318	1481

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/ULP

   S: 2    svtnedlkcLeegeflnDviidfylkylvlekl.kkekverihifssffykklkqkerrrvktwtrkvdlfekdlifvpinea.aHWslavvcfkk 95
           ++t++d+ +  +ge+lnD ii+fy+  l + +  ++ +++ + ++++ff+ +l q ++  v++wtrkvdlf+kd+i vp++ + +HW++a++ +++
   Q: 1318 QITTDDIFTFVDGEWLNDAIINFYMSMLTERSEkRAGELPATYAMNTFFMPRLLQAGYAGVRRWTRKVDLFSKDIIPVPVHCGnVHWCMAIIHLRN 1413
           79************************665555555678999*****************************************88************ PP
   S: 96   ksilllDSlrgasksnvvkklreylevevkkkskrefskeklkgsnpk.vpqQkNssDCGvyvlqyves 163
           k+i+++DS+ g  ++ ++++l +yl++e+ +k+k+ f+ + +  +n + +p+Q NssDCGv+ ++++e+
   Q: 1414 KTIFYYDSM-GRPNQPALDALVKYLHEESLDKRKQPFDMTGFVVENAQnIPRQGNSSDCGVFSCMFAEY 1481
           *********.999****************************99998888*****************987 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MSLPPEDTDL STNSAYESAL QIASNVSAAR VVGSAVGQRF SPSPAAHPNV IERVASHVDS 60
RRSTFPSWGN PSVAPRGSEE AAANATATQL LWAENQGLPT SHLLPTEQAF ETLNTNAYCS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTATTATAG AGCAATATCT TGTACGGTCA TACTAAGGCA CCAGTACGCC AAAACCGAAA 60
TTTTCTTTCT TTACTCAATT TTCATCGAGC TAAGTTGCGA AAATTTTCTC AAGTCACAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR003653--Peptidase_C48_C

PROSITE

PS50600--ULP_PROTEASE

Pfam

PF02902--Peptidase_C48

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005637--C:nuclear inner membrane
GO:0005643--C:nuclear pore
GO:0005634--C:nucleus
GO:0004175--F:endopeptidase activity
GO:0016929--F:SUMO-specific protease activity
GO:0071456--P:cellular response to hypoxia
GO:0021952--P:central nervous system projection neuron axonogenesis
GO:0060997--P:dendritic spine morphogenesis
GO:0050728--P:negative regulation of inflammatory response
GO:0035204--P:negative regulation of lamellocyte differentiation
GO:0045751--P:negative regulation of Toll signaling pathway
GO:0016926--P:protein desumoylation
GO:0006508--P:proteolysis

KEGG

dme:Dmel_CG12359

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001885	Ailuropoda melanoleuca	50.75	6.00e-58	218.00
IUUC-Atr-003110	Amborella trichopoda	31.82	3.00e-32	132.00
IUUC-Apl-004162	Anas platyrhynchos	50.75	2.00e-57	216.00
IUUC-Aca-005011	Anolis carolinensis	50.25	1.00e-57	217.00
IUUC-Ago-007930	Ashbya gossypii	27.20	7.00e-22	97.80
IUUC-Ate-010312	Aspergillus terreus	34.48	9.00e-16	78.60
IUUC-Bta-012319	Bos taurus	50.75	2.00e-57	216.00
IUUC-Bol-015882	Brassica oleracea	32.62	2.00e-35	142.00
IUUC-Bra-017525	Brassica rapa	33.62	2.00e-34	139.00
IUUC-Cel-018426	Caenorhabditis elegans	46.19	4.00e-53	202.00
IUUC-Cja-019463	Callithrix jacchus	51.26	4.00e-58	218.00
IUUC-Cfa-020654	Canis familiaris	50.75	2.00e-57	216.00
IUUC-Cpo-022243	Cavia porcellus	50.25	8.00e-57	214.00
IUUC-Csa-023353	Chlorocebus sabaeus	30.07	1.00e-30	127.00
IUUC-Cho-024917	Choloepus hoffmanni	50.51	1.00e-56	213.00
IUUC-Cin-025277	Ciona intestinalis	49.73	1.00e-50	191.00
IUUC-Csv-026222	Ciona savignyi	46.23	5.00e-50	189.00
IUUC-Cne-026848	Cryptococcus neoformans	34.03	2.00e-26	112.00
IUUC-Dre-028702	Danio rerio	49.75	1.00e-57	217.00
IUUC-Dno-029507	Dasypus novemcinctus	50.75	2.00e-57	216.00
IUUC-Ete-033044	Echinops telfairi	29.72	1.00e-30	127.00
IUUC-Eca-033511	Equus caballus	51.26	7.00e-58	218.00
IUUC-Eeu-034586	Erinaceus europaeus	51.26	7.00e-58	217.00
IUUC-Fca-036580	Felis catus	50.75	3.00e-56	212.00
IUUC-Fal-037325	Ficedula albicollis	52.20	1.00e-53	201.00
IUUC-Gga-040844	Gallus gallus	51.11	2.00e-52	199.00
IUUC-Gac-042067	Gasterosteus aculeatus	47.24	9.00e-55	206.00
IUUC-Hsa-046229	Homo sapiens	50.75	2.00e-57	216.00
IUUC-Itr-048917	Ictidomys tridecemlineatus	50.75	1.00e-57	217.00
IUUC-Lch-049483	Latimeria chalumnae	51.26	5.00e-59	221.00
IUUC-Lpe-051604	Leersia perrieri	34.97	1.00e-30	127.00
IUUC-Loc-052844	Lepisosteus oculatus	42.72	5.00e-59	221.00
IUUC-Lma-052978	Leptosphaeria maculans	30.30	7.00e-17	81.60
IUUC-Laf-053658	Loxodonta africana	50.75	2.00e-57	216.00
IUUC-Mcc-055432	Macaca mulatta	51.26	2.00e-58	219.00
IUUC-Meu-055923	Macropus eugenii	50.53	1.00e-54	206.00
IUUC-Mor-056912	Magnaporthe oryzae	27.13	3.00e-12	67.40
IUUC-Mpo-057341	Magnaporthe poae	25.26	4.00e-14	73.20
IUUC-Mla-059033	Melampsora laricipopulina	39.02	1.00e-38	152.00
IUUC-Mga-059454	Meleagris gallopavo	51.26	9.00e-58	217.00
IUUC-Mvi-060257	Microbotryum violaceum	33.82	3.00e-31	129.00
IUUC-Mmr-061104	Microcebus murinus	50.75	3.00e-58	219.00
IUUC-Mdo-062439	Monodelphis domestica	50.75	4.00e-58	217.00
IUUC-Mmu-063629	Mus musculus	50.25	1.00e-56	214.00
IUUC-Mac-064839	Musa acuminata	35.68	2.00e-30	126.00
IUUC-Mpu-066790	Mustela putorius furo	45.78	1.00e-57	216.00
IUUC-Mlu-067849	Myotis lucifugus	50.75	1.00e-57	216.00
IUUC-Nle-069931	Nomascus leucogenys	50.75	4.00e-57	215.00
IUUC-Opr-070528	Ochotona princeps	50.00	2.00e-54	206.00
IUUC-Ont-072628	Oreochromis niloticus	47.24	7.00e-57	214.00
IUUC-Oan-073271	Ornithorhynchus anatinus	34.63	4.00e-29	122.00
IUUC-Ocu-074506	Oryctolagus cuniculus	50.75	4.00e-57	214.00
IUUC-Oba-074983	Oryza barthii	34.73	6.00e-33	133.00
IUUC-Obr-076231	Oryza brachyantha	37.56	5.00e-32	130.00
IUUC-Ogu-078658	Oryza glumaepatula	33.04	8.00e-29	120.00
IUUC-Oin-079674	Oryza indica	34.73	3.00e-32	132.00
IUUC-Olo-080443	Oryza longistaminata	34.73	7.00e-33	134.00
IUUC-Ome-081681	Oryza meridionalis	35.00	5.00e-32	131.00
IUUC-Opu-083766	Oryza punctata	35.15	3.00e-30	125.00
IUUC-Oru-084743	Oryza rufipogon	34.73	3.00e-32	132.00
IUUC-Osa-085764	Oryza sativa	34.73	3.00e-32	132.00
IUUC-Oga-088308	Otolemur garnettii	51.41	7.00e-53	201.00
IUUC-Oar-090004	Ovis aries	50.75	2.00e-57	216.00
IUUC-Ptr-091310	Pan troglodytes	50.51	8.00e-57	214.00
IUUC-Pan-092232	Papio anubis	50.75	4.00e-57	215.00
IUUC-Psi-093705	Pelodiscus sinensis	52.26	1.00e-59	223.00
IUUC-Pma-094606	Petromyzon marinus	50.50	3.00e-54	203.00
IUUC-Ppa-095465	Physcomitrella patens	36.18	2.00e-34	139.00
IUUC-Pfo-096571	Poecilia formosa	46.23	2.00e-55	209.00
IUUC-Pab-097640	Pongo abelii	50.75	3.00e-57	216.00
IUUC-Pca-100611	Procavia capensis	50.51	5.00e-57	214.00
IUUC-Pva-102437	Pteropus vampyrus	45.87	7.00e-57	214.00
IUUC-Pgr-103502	Puccinia graminis	34.82	1.00e-34	140.00
IUUC-Pte-104020	Pyrenophora teres	26.87	6.00e-15	75.50
IUUC-Pyt-104575	Pyrenophora triticirepentis	27.36	3.00e-16	79.70
IUUC-Rno-105520	Rattus norvegicus	49.75	4.00e-57	215.00
IUUC-Sce-106442	Saccharomyces cerevisiae	32.88	1.00e-27	117.00
IUUC-Sha-106929	Sarcophilus harrisii	50.75	4.00e-58	217.00
IUUC-Sja-107906	Schizosaccharomyces japonicus	43.14	2.00e-46	179.00
IUUC-Sly-111206	Solanum lycopersicum	35.68	8.00e-32	130.00
IUUC-Sbi-114067	Sorghum bicolor	37.56	3.00e-37	149.00
IUUC-Sre-115071	Sporisorium reilianum	30.91	1.00e-29	124.00
IUUC-Ssc-115376	Sus scrofa	50.25	3.00e-57	215.00
IUUC-Tgu-116621	Taeniopygia guttata	51.26	2.00e-58	218.00
IUUC-Tsy-119028	Tarsius syrichta	45.96	4.00e-46	178.00
IUUC-Tni-120194	Tetraodon nigroviridis	48.24	4.00e-58	218.00
IUUC-Tae-125765	Triticum aestivum	33.45	9.00e-33	134.00
IUUC-Tur-126817	Triticum urartu	33.79	1.00e-32	133.00
IUUC-Tbe-127763	Tupaia belangeri	50.77	8.00e-38	150.00
IUUC-Uma-129373	Ustilago maydis	32.23	4.00e-29	122.00
IUUC-Vpa-130375	Vicugna pacos	50.51	6.00e-57	214.00
IUUC-Vvi-131660	Vitis vinifera	31.84	6.00e-29	121.00
IUUC-Xtr-132587	Xenopus tropicalis	49.75	3.00e-58	219.00
IUUC-Xma-133896	Xiphophorus maculatus	46.23	2.00e-55	209.00
IUUC-Yli-134367	Yarrowia lipolytica	32.20	3.00e-35	142.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence