iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071433

Ensembl Protein ID

ENSONIP00000011335.1

UniProt Accession

I3JR41; I3JR41_ORENI

Genbank Protein ID

ENSONIP00000011335

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01027855

Gene Name

ube2kb; ube2k

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000009013.1	ENSONIT00000011344.1	ENSONIP00000011335.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	4.60e-46	156.4	8	146
UBD/Alpha-Helix/UBA	5.00e-10	39.6	162	199
UBD/UBC-like/UBD_UBC	1.10e-72	243.0	8	149

Active Site

Position(s)	Description	Evidence
92	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    Rlkkelkel...ekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyen.GkvClsi 85
           R+k+e+ke+   e++++++i++++vde ++te++ +i Gp+dtpYegg ++lei++pe+YPf+PPkv+f+tki+hPn+++  G++Cl+i
   Q: 8    RIKREFKEVlksEETSKNQIKVDLVDE-NFTELRGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSVtGAICLDI 95
           7888888873335556699********.9***************************************************99******* PP
   S: 86   lkeeekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           lk  ++W +a+++++vlls+q+lla ++p++p+++ +a+++k+n+e++k+++r
   Q: 96   LK--DQWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVANQYKQNPEMFKQTAR 146
           *9..**********************************************986 PP

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraannnleaAveyLld 40
           ++ k+++l++MGFd+++++ aL + ++++e A+e+Ll+
   Q: 162  YTRKIDKLCAMGFDKNAVIAALSSKSWDVETATELLLS 199
           6789********************************97 PP

UBD/UBC-like/UBD_UBC

   S: 1    rikkelkdllrdeea...qisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpnins.ngsicldil 85
           rik+e+k++l++ee+   qi++dlvd++++elr++iagppd+pyegg+++l+ik+p++ypf+ppkv+fitki+hpni+s +g+icldil
   Q: 8    RIKREFKEVLKSEETsknQIKVDLVDENFTELRGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSvTGAICLDIL 96
           8*************9999*********************************************************************** PP
   S: 86   rsqwsaaltlskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           ++qw+aa+tl++vllsl++lla+aepddp++a++a++yk+++e++k++ar+w+
   Q: 97   KDQWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVANQYKQNPEMFKQTARLWS 149
           ****************************************************5 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MANIAVQRIK REFKEVLKSE ETSKNQIKVD LVDENFTELR GEIAGPPDTP YEGGRYQLEI 60
KIPETYPFNP PKVRFITKIW HPNISSVTGA ICLDILKDQW AAAMTLRTVL LSLQALLAAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCAACA TTGCGGTCCA AAGGATCAAA CGGGAGTTCA AAGAAGTTCT CAAAAGCGAA 60
GAGGTGCGGT AACGCTACCG GCTTATTTTC ACTTCTACTC AGCTCTTTCT TTAAAATTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR015940--UBA
IPR009060--UBA-like
IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50030--UBA
PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00627--UBA
PF00179--UQ_con

SMART

SM00165--UBA

Gene Ontology

GO:0005524--F:ATP binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-003063	Amborella trichopoda	48.45	4.00e-40	157.00
IUUC-Aca-004565	Anolis carolinensis	91.05	4.00e-96	343.00
IUUC-Aly-006390	Arabidopsis lyrata	48.22	8.00e-45	172.00
IUUC-Acl-008189	Aspergillus clavatus	49.03	2.00e-27	116.00
IUUC-Afl-008489	Aspergillus flavus	40.93	2.00e-28	119.00
IUUC-Afu-008850	Aspergillus fumigatus	41.59	1.00e-29	123.00
IUUC-Ani-009361	Aspergillus nidulans	50.00	3.00e-26	111.00
IUUC-Ang-009548	Aspergillus niger	40.47	3.00e-27	115.00
IUUC-Aor-010105	Aspergillus oryzae	40.93	2.00e-28	119.00
IUUC-Ate-010389	Aspergillus terreus	41.47	1.00e-28	120.00
IUUC-Bgr-012255	Blumeria graminis	47.77	3.00e-33	135.00
IUUC-Bci-013806	Botrytis cinerea	40.09	3.00e-36	145.00
IUUC-Bdi-015024	Brachypodium distachyon	48.73	4.00e-41	160.00
IUUC-Bol-015985	Brassica oleracea	48.22	5.00e-45	174.00
IUUC-Bra-016805	Brassica rapa	48.22	2.00e-45	174.00
IUUC-Cgl-026449	Colletotrichum gloeosporioides	40.96	4.00e-34	138.00
IUUC-Dno-029169	Dasypus novemcinctus	90.00	5.00e-99	353.00
IUUC-Dor-030382	Dipodomys ordii	82.50	2.00e-85	308.00
IUUC-Dse-031335	Dothistroma septosporum	50.32	2.00e-36	145.00
IUUC-Dme-032003	Drosophila melanogaster	69.35	1.00e-72	265.00
IUUC-Ete-032868	Echinops telfairi	87.50	1.00e-85	308.00
IUUC-Fso-038296	Fusarium solani	42.00	1.00e-35	142.00
IUUC-Gga-041018	Gallus gallus	97.00	2.00e-107	381.00
IUUC-Gma-042779	Glycine max	50.77	5.00e-44	170.00
IUUC-Lch-050588	Latimeria chalumnae	69.67	4.00e-77	280.00
IUUC-Lpe-051070	Leersia perrieri	48.73	2.00e-33	135.00
IUUC-Loc-052549	Lepisosteus oculatus	98.00	2.00e-108	384.00
IUUC-Mtr-058002	Medicago truncatula	50.26	2.00e-43	168.00
IUUC-Mga-059254	Meleagris gallopavo	96.11	4.00e-95	340.00
IUUC-Mac-065447	Musa acuminata	48.73	9.00e-42	162.00
IUUC-Mpu-066407	Mustela putorius furo	96.50	3.00e-106	378.00
IUUC-Nfi-068517	Neosartorya fischeri	41.59	1.00e-29	123.00
IUUC-Oba-075530	Oryza barthii	49.49	1.00e-32	132.00
IUUC-Ogl-077606	Oryza glaberrima	49.49	1.00e-32	132.00
IUUC-Ogu-078238	Oryza glumaepatula	49.49	1.00e-32	132.00
IUUC-Oin-079643	Oryza indica	49.49	2.00e-32	131.00
IUUC-Ome-081274	Oryza meridionalis	49.49	1.00e-32	132.00
IUUC-Oni-082651	Oryza nivara	49.49	1.00e-32	132.00
IUUC-Opu-083933	Oryza punctata	49.49	2.00e-32	132.00
IUUC-Oru-085054	Oryza rufipogon	49.49	2.00e-32	132.00
IUUC-Osa-085716	Oryza sativa	49.49	2.00e-32	131.00
IUUC-Ola-087278	Oryzias latipes	99.00	3.00e-109	387.00
IUUC-Oga-088897	Otolemur garnettii	90.40	4.00e-97	347.00
IUUC-Pan-092034	Papio anubis	96.09	1.00e-94	338.00
IUUC-Pma-094115	Petromyzon marinus	82.91	1.00e-89	322.00
IUUC-Pno-095102	Phaeosphaeria nodorum	41.23	4.00e-39	154.00
IUUC-Pfo-096940	Poecilia formosa	100.00	4.00e-110	389.00
IUUC-Pop-099543	Populus trichocarpa	49.75	5.00e-45	174.00
IUUC-Ppe-101789	Prunus persica	48.45	2.00e-37	149.00
IUUC-Pgr-103643	Puccinia graminis	46.75	9.00e-38	150.00
IUUC-Ptt-103772	Puccinia triticina	47.95	2.00e-36	145.00
IUUC-Pte-104370	Pyrenophora teres	40.28	3.00e-37	148.00
IUUC-Pyt-104592	Pyrenophora triticirepentis	39.81	1.00e-36	146.00
IUUC-Sha-106624	Sarcophilus harrisii	90.00	6.00e-101	359.00
IUUC-Ssl-108609	Sclerotinia sclerotiorum	41.94	2.00e-40	158.00
IUUC-Smo-109656	Selaginella moellendorffii	50.00	2.00e-41	161.00
IUUC-Sly-110978	Solanum lycopersicum	48.73	5.00e-45	173.00
IUUC-Stu-112088	Solanum tuberosum	48.73	2.00e-45	174.00
IUUC-Sar-113285	Sorex araneus	80.45	4.00e-73	266.00
IUUC-Tgu-117427	Taeniopygia guttata	95.56	1.00e-94	338.00
IUUC-Tru-118618	Takifugu rubripes	95.00	5.00e-105	373.00
IUUC-Tca-121446	Theobroma cacao	49.75	1.00e-45	176.00
IUUC-Tre-122053	Trichoderma reesei	36.32	3.00e-31	128.00
IUUC-Tvi-122533	Trichoderma virens	37.81	1.00e-31	130.00
IUUC-Tae-124726	Triticum aestivum	49.24	6.00e-34	137.00
IUUC-Tbe-127752	Tupaia belangeri	93.00	8.00e-102	362.00
IUUC-Ttr-128287	Tursiops truncatus	96.09	1.00e-94	338.00
IUUC-Vvi-131429	Vitis vinifera	46.70	5.00e-42	164.00
IUUC-Xtr-132710	Xenopus tropicalis	80.69	2.00e-93	334.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence