iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Obr-076886

Ensembl Protein ID

OB02G15380.1

UniProt Accession

J3LA71; J3LA71_ORYBR

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
OB02G15380	OB02G15380.1	OB02G15380.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	1.50e-61	209.3	2	319

Active Site

Position(s)	Description	Evidence
81	Nucleophile	{ECO:0000256\|PIRSR:PIRSR038120-1}
154	Proton donor	{ECO:0000256\|PIRSR:PIRSR038120-1}

Domain Profile

DUB/UCH

   S: 7    ewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqvigNsCatyA 103
           +w ++e dPg+ft+l+++  +k+  qv+elysLd + l+ + +pv+gl+ l+k+ + +e +r +           +d + ++ffa+q i+N+Cat+A
   Q: 2    SWATIENDPGIFTELLQQMQLKGL-QVDELYSLDLDALSDL-QPVYGLIVLYKWRPPEEDERPI-----------KDPVPNLFFANQIINNACATQA 85
           7***********************.****************.9**************9999944...........489******************* PP
   S: 104  llsvllncedklldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsyvningrlyeldglkpfP 200
           +lsvlln       l ++l++lke+ k   pe k+la+ n + ++ + ns+ r+e  +e++      + ++++++hf+syv+++g lyeldglk+ P
   Q: 86   ILSVLLNSPGI--TLSEELKKLKEFAKDLPPELKGLAIVNCESIRLASNSFSRPEVPEEQKS-----STKDDDVYHFISYVPVDGVLYELDGLKEGP 175
           *******8776..8****************************************98777644.....445799************************ PP
   S: 201  ldlgkk....keteelkdklkvvraflerikllesdeirfnllaivadrrviktlrlnvlkid.................keLlkLlkdieseeeki 276
           + lgk+      +  + + ++ v+   e i+  +++eirf+++ai ++rr ++tl l+ l+                     + + l ++ +++e  
   Q: 176  ISLGKCpgsgVGDIGWLKMVRPVI--QEHIDRFSQNEIRFSVMAILKNRREMYTLELKELQRKrenllaqmgdpsanrhgPSVEQSLAEVAAQIEAV 270
           *****9655445678999999999..*****************************99877777899************9945556677778888888 PP
   S: 277  eaqlddekekrkkfkiddirRtenydeficifikdlaregilrklveet 325
            +++  e+ek kk+k ++irR++ny+ f++ f+k+l ++++l+ l e+ 
   Q: 271  TEKIIMEEEKWKKWKTENIRRKHNYVPFLFNFLKMLEEKQQLKPLIEKA 319
           8888889*************************************99984 PP

Organism

Oryza brachyantha

Protein Sequence
(Fasta)

MSWATIENDP GIFTELLQQM QLKGLQVDEL YSLDLDALSD LQPVYGLIVL YKWRPPEEDE 60
RPIKDPVPNL FFANQIINNA CATQAILSVL LNSPGITLSE ELKKLKEFAK DLPPELKGLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTTTGAGAC TGCGCTGTAT ATCTGTAAGT ATATTTGACC TTTCATGAAC TATTCAATTA 60
CAACCTTTGA GAACCTTGTT GTATTGGAAT CAAATTGACA ATAAAGACAA GATTTTTTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR017390--Ubiquitinyl_hydrolase_UCH37

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005622--C:intracellular
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

obr:102713518

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000878	Aegilops tauschii	82.46	7.00e-145	505.00
IUUC-Bdi-014551	Brachypodium distachyon	86.11	2.00e-156	543.00
IUUC-Oba-075354	Oryza barthii	92.42	1.00e-168	585.00
IUUC-Ogu-078511	Oryza glumaepatula	92.38	1.00e-167	581.00
IUUC-Olo-080482	Oryza longistaminata	91.82	5.00e-168	582.00
IUUC-Oni-082729	Oryza nivara	91.52	7.00e-167	578.00
IUUC-Opu-084139	Oryza punctata	92.12	3.00e-169	586.00
IUUC-Oru-084441	Oryza rufipogon	92.73	2.00e-169	587.00
IUUC-Osa-085606	Oryza sativa	92.73	3.00e-169	586.00
IUUC-Sit-110523	Setaria italica	89.31	1.00e-157	547.00
IUUC-Sbi-114404	Sorghum bicolor	86.97	5.00e-150	522.00
IUUC-Tae-123169	Triticum aestivum	85.93	1.00e-148	518.00
IUUC-Tur-126366	Triticum urartu	85.49	6.00e-143	499.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence