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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-063996
Ensembl Protein ID ENSMUSP00000099744.4
UniProt Accession Q5SRX1; A0JP66; Q5SRX7; Q5SRY0; Q6P5D7; Q8C6J0; Q8C935; Q8CB51; Q8R4H1; TM1L2_MOUSE
Genbank Protein ID AAL77033.1; BAC29576.1; BAC31458.1; BAC35813.1; BAE38537.1; CAI24070.1; CAI24070.1; CAI24071.1; CAI24071.1; CAI24072.1; CAI24072.1; CAI25761.1; CAI25761.1; CAI25762.1; CAI25762.1; CAI25763.1; CAI25763.1; AAH62947.2; AAI27267.1
Protein Name TOM1-like protein 2; Target of Myb-like protein 2
Genbank Nucleotide ID AF467887; AK036788; AK043095; AK054531; AK166040; AL596090; AL669954; AL596090; AL669954; AL596090; AL669954; AL669954; AL596090; AL669954; AL596090; AL669954; AL596090; BC062947; BC127266
Gene Name Tom1l2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000000538.18 ENSMUST00000102683.10 ENSMUSP00000099744.4
ENSMUSG00000000538.18 ENSMUST00000093048.12 ENSMUSP00000090736.6
ENSMUSG00000000538.18 ENSMUST00000093046.12 ENSMUSP00000090734.6
ENSMUSG00000000538.18 ENSMUST00000133420.7 ENSMUSP00000117623.1
ENSMUSG00000000538.18 ENSMUST00000143124.7 ENSMUSP00000121936.1
ENSMUSG00000000538.18 ENSMUST00000064019.14 ENSMUSP00000063414.8
ENSMUSG00000000538.18 ENSMUST00000102682.4 ENSMUSP00000099743.4
ENSMUSG00000000538.18 ENSMUST00000095254.11 ENSMUSP00000092884.5
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitecircBasemiRTarBasemicroRNA
TRANSFACRepTarRAID2
Protein-protein Interaction
IIDMentha
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
Phospho.ELMUniProtPHOSIDAmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/Alpha-Helix/VHS 9.10e-47 159.5 20 152
UBD/Alpha-Helix/GAT 4.60e-27 95.7 216 306
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/Alpha-Helix/VHS
   S: 1    atselvtsedwelileicdliqetkegakdalralrkri.nnknphvalraLtlLdscvsnCgkkfhvevaskdllee..lrell.kne 85
           at+ +++sedw+l++eicd+i+et+eg+kda+ral+kr+ +n+n  ++++aLt+L++cv+nCg++fh++va++d++++  ++ +  kn+
   Q: 20   ATDGSLQSEDWTLNMEICDIINETEEGPKDAIRALKKRLsGNRNYREVMLALTVLETCVKNCGHRFHLLVANRDFIDSvlVKIISpKNN 108
           68999**********************************99************************************985666669999 PP
   S: 86   nepkvieKlkalivsWadelknepalslivaliktlkeeGlefp 129
           +++ v +K++ali++Wad+++++p+l+++v+++++lk++G+efp
   Q: 109  PPTIVQDKVLALIQAWADAFRSSPDLTGVVHIYEELKRRGIEFP 152
           9******************************************8 PP
   

   UBD/Alpha-Helix/GAT
   S: 36   dkaekikkliseleevksnvkllnemlselspegeepednellqelyetckaarpkllklieeeedndellaellkanDelnqvlnkyk 124
           +++e+i +l+sel+ v++n+k+++eml+e++p++e+++d ellqel++tc+a+++++++li++ ++n+e+++ell++nD+ln+v+++y+
   Q: 216  ANSEQIARLRSELDIVRGNTKVMSEMLTEMVPGQEDSSDLELLQELNRTCRAMQHRIVELISR-VSNEEVTEELLHVNDDLNNVFLRYE 303
           689************************************************************.************************* PP
   S: 125  qlk 127
           +++
   Q: 304  RFE 306
           997 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Probable role in protein transport. May regulate growth factor-induced mitogenic signaling (By similarity).
 Probable role in protein transport. May regulate growth factor-induced mitogenic signaling (By similarity).
Protein Sequence
(Fasta)
MEFLLGNPFS TPVGQCLEKA TDGSLQSEDW TLNMEICDII NETEEGPKDA IRALKKRLSG 60
NRNYREVMLA LTVLETCVKN CGHRFHLLVA NRDFIDSVLV KIISPKNNPP TIVQDKVLAL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063996|UBD,VHS;UBD,GAT|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGTGGGGCGG GGGCAAGTGT CAGTCAGGGC AGAACGCGGC GCGGGCAGCG GAGACCCGTG 60
GCACACAGGA GTCCGGGCTG GAACGAGGCC CGCCGAGATG GAGTTCCTGC TGGGGAATCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063996|UBD,VHS;UBD,GAT|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0597--Phosphoprotein
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
Interpro

IPR008942--ENTH_VHS
IPR004152--GAT_dom
IPR014645--TOM1
IPR027429--TOM1L2
IPR002014--VHS_dom
PROSITE

PS50909--GAT
PS50179--VHS
Pfam

PF03127--GAT
PF00790--VHS
SMART

SM00288--VHS
Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005622--C:intracellular
GO:0030276--F:clathrin binding
GO:0019901--F:protein kinase binding
GO:0006886--P:intracellular protein transport
GO:0045839--P:negative regulation of mitotic nuclear division
GO:0007165--P:signal transduction
KEGG mmu:216810
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000135 Aegilops tauschii 30.15 5.00e-26 112.00
IUUC-Aml-002171 Ailuropoda melanoleuca 92.28 0.00e+00 836.00
IUUC-Atr-003138 Amborella trichopoda 32.99 4.00e-28 119.00
IUUC-Apl-003931 Anas platyrhynchos 87.12 0.00e+00 785.00
IUUC-Aca-004547 Anolis carolinensis 66.60 1.00e-163 569.00
IUUC-Aly-005656 Arabidopsis lyrata 34.19 2.00e-36 147.00
IUUC-Ath-007359 Arabidopsis thaliana 31.82 2.00e-35 144.00
IUUC-Ame-011059 Astyanax mexicanus 68.07 0.00e+00 661.00
IUUC-Bta-012995 Bos taurus 84.87 0.00e+00 783.00
IUUC-Bdi-015001 Brachypodium distachyon 32.41 7.00e-32 132.00
IUUC-Bol-015832 Brassica oleracea 33.33 2.00e-36 147.00
IUUC-Bra-017805 Brassica rapa 32.47 1.00e-36 147.00
IUUC-Cja-019153 Callithrix jacchus 93.25 0.00e+00 830.00
IUUC-Cfa-020935 Canis familiaris 89.06 0.00e+00 849.00
IUUC-Cpo-021763 Cavia porcellus 89.35 0.00e+00 843.00
IUUC-Cre-022771 Chlamydomonas reinhardtii 34.36 5.00e-16 77.80
IUUC-Csa-023899 Chlorocebus sabaeus 89.37 0.00e+00 864.00
IUUC-Cin-025779 Ciona intestinalis 43.55 3.00e-70 258.00
IUUC-Dre-028784 Danio rerio 69.20 0.00e+00 711.00
IUUC-Dno-029588 Dasypus novemcinctus 88.45 0.00e+00 785.00
IUUC-Dor-030371 Dipodomys ordii 76.13 0.00e+00 645.00
IUUC-Dme-032144 Drosophila melanogaster 43.02 6.00e-101 361.00
IUUC-Eca-033664 Equus caballus 93.06 0.00e+00 831.00
IUUC-Eeu-035062 Erinaceus europaeus 71.01 0.00e+00 657.00
IUUC-Fca-036096 Felis catus 92.53 0.00e+00 879.00
IUUC-Fal-036951 Ficedula albicollis 84.56 0.00e+00 789.00
IUUC-Gmo-038942 Gadus morhua 62.69 7.00e-172 597.00
IUUC-Gga-040378 Gallus gallus 88.95 0.00e+00 803.00
IUUC-Gac-042242 Gasterosteus aculeatus 70.55 0.00e+00 716.00
IUUC-Gma-043428 Glycine max 32.12 2.00e-34 141.00
IUUC-Ggo-045180 Gorilla gorilla 94.87 0.00e+00 882.00
IUUC-Hsa-045697 Homo sapiens 94.87 0.00e+00 882.00
IUUC-Hvu-047560 Hordeum vulgare 30.24 5.00e-31 128.00
IUUC-Itr-048308 Ictidomys tridecemlineatus 79.14 0.00e+00 754.00
IUUC-Lch-049647 Latimeria chalumnae 80.49 0.00e+00 750.00
IUUC-Lpe-051451 Leersia perrieri 33.33 3.00e-32 133.00
IUUC-Loc-052081 Lepisosteus oculatus 80.08 0.00e+00 812.00
IUUC-Laf-053664 Loxodonta africana 79.37 0.00e+00 732.00
IUUC-Mcc-055637 Macaca mulatta 89.55 0.00e+00 865.00
IUUC-Meu-056014 Macropus eugenii 75.54 0.00e+00 700.00
IUUC-Mtr-058035 Medicago truncatula 29.97 2.00e-32 134.00
IUUC-Mga-060056 Meleagris gallopavo 81.47 0.00e+00 681.00
IUUC-Mvi-060415 Microbotryum violaceum 26.37 2.00e-15 77.80
IUUC-Mmr-060929 Microcebus murinus 89.35 0.00e+00 804.00
IUUC-Mdo-061814 Monodelphis domestica 86.59 0.00e+00 863.00
IUUC-Mac-064731 Musa acuminata 32.30 3.00e-35 144.00
IUUC-Mpu-065820 Mustela putorius furo 90.82 0.00e+00 823.00
IUUC-Nle-069131 Nomascus leucogenys 94.30 0.00e+00 809.00
IUUC-Opr-070780 Ochotona princeps 84.98 0.00e+00 722.00
IUUC-Ont-072357 Oreochromis niloticus 69.80 0.00e+00 678.00
IUUC-Oan-072790 Ornithorhynchus anatinus 86.54 1.00e-174 605.00
IUUC-Ocu-074458 Oryctolagus cuniculus 87.44 0.00e+00 721.00
IUUC-Oba-075564 Oryza barthii 32.29 1.00e-33 138.00
IUUC-Obr-076278 Oryza brachyantha 32.42 7.00e-35 142.00
IUUC-Ogl-077758 Oryza glaberrima 32.29 1.00e-33 138.00
IUUC-Ogu-078839 Oryza glumaepatula 32.29 8.00e-34 138.00
IUUC-Oin-079919 Oryza indica 32.29 1.00e-33 138.00
IUUC-Olo-080861 Oryza longistaminata 30.16 1.00e-32 134.00
IUUC-Ome-081795 Oryza meridionalis 32.88 3.00e-33 136.00
IUUC-Oni-082876 Oryza nivara 31.94 3.00e-33 137.00
IUUC-Opu-083285 Oryza punctata 34.03 4.00e-34 139.00
IUUC-Oru-084640 Oryza rufipogon 32.29 9.00e-34 138.00
IUUC-Osa-085855 Oryza sativa 32.29 1.00e-33 138.00
IUUC-Ola-087001 Oryzias latipes 69.27 0.00e+00 656.00
IUUC-Olu-087840 Ostreococcus lucimarinus 34.11 1.00e-15 77.80
IUUC-Oga-088302 Otolemur garnettii 92.90 0.00e+00 850.00
IUUC-Ptr-091081 Pan troglodytes 94.48 0.00e+00 874.00
IUUC-Pan-092566 Papio anubis 89.55 0.00e+00 865.00
IUUC-Psi-093744 Pelodiscus sinensis 88.56 0.00e+00 796.00
IUUC-Pma-094514 Petromyzon marinus 64.09 5.00e-126 443.00
IUUC-Ppa-095533 Physcomitrella patens 32.30 1.00e-32 134.00
IUUC-Pfo-096489 Poecilia formosa 70.06 0.00e+00 684.00
IUUC-Pab-098769 Pongo abelii 89.21 0.00e+00 829.00
IUUC-Pop-099695 Populus trichocarpa 30.28 1.00e-32 134.00
IUUC-Ppe-101305 Prunus persica 32.35 3.00e-35 143.00
IUUC-Pva-102889 Pteropus vampyrus 81.07 0.00e+00 720.00
IUUC-Rno-105379 Rattus norvegicus 94.32 0.00e+00 912.00
IUUC-Smo-109609 Selaginella moellendorffii 35.06 7.00e-20 91.70
IUUC-Sit-109878 Setaria italica 31.85 2.00e-33 137.00
IUUC-Sly-111100 Solanum lycopersicum 33.22 1.00e-35 145.00
IUUC-Stu-112728 Solanum tuberosum 31.33 6.00e-13 68.60
IUUC-Sbi-114813 Sorghum bicolor 31.80 6.00e-36 145.00
IUUC-Tgu-116705 Taeniopygia guttata 88.37 0.00e+00 765.00
IUUC-Tru-117717 Takifugu rubripes 69.64 0.00e+00 673.00
IUUC-Tsy-119063 Tarsius syrichta 83.64 0.00e+00 663.00
IUUC-Tni-120694 Tetraodon nigroviridis 57.03 3.00e-142 498.00
IUUC-Tca-121503 Theobroma cacao 32.89 4.00e-34 139.00
IUUC-Tae-124026 Triticum aestivum 33.22 5.00e-29 122.00
IUUC-Tur-126378 Triticum urartu 29.13 1.00e-27 118.00
IUUC-Tbe-128123 Tupaia belangeri 79.75 2.00e-173 601.00
IUUC-Vvi-131122 Vitis vinifera 31.51 5.00e-34 139.00
IUUC-Xtr-132682 Xenopus tropicalis 81.18 0.00e+00 799.00
IUUC-Xma-134041 Xiphophorus maculatus 66.85 0.00e+00 648.00
Created Date 25-Jun-2017

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