iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020994

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03011498

Gene Name

AMBRA1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000009193.4	ENSCAFT00000039701.2	ENSCAFP00000035586.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.50e-08	32.9	93	126

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd..tllvsGsdDgtikvWDlr 31
           gH    +c+ f ++  +l++sG+ Dg +++WDl+
   Q: 93   GHRRTPWCVTFhPTisGLIASGCLDGEVRIWDLH 126
           6777779*****76779***************97 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MKVVPEKNAV RILWGRERGT RAFGAQRLLQ ELVEDKTRWM KWEGKRVELP DSPRSTFLLA 60
FSPDRTLLAS THVNHNIYIT EVKTGKCVHS LIGHRRTPWC VTFHPTISGL IASGCLDGEV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCATACTTG AGGTCTCAGG CTTTTGGAAT AAAATTAAAA AGCATGTTTT TTTTTTTTTT 60
TTTGCTTTTT GTCCTGCCTT AGGTCAGCCT ACAAAACCGA GTTTTCCCAG CTTCTCTTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

SMART

SM00320--WD40

Gene Ontology

GO:0005930--C:axoneme
GO:0005829--C:cytosol
GO:0043231--C:intracellular membrane-bounded organelle
GO:0005739--C:mitochondrion
GO:0045335--C:phagocytic vesicle
GO:0006914--P:autophagy
GO:0008285--P:negative regulation of cell proliferation
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0021915--P:neural tube development
GO:0098779--P:positive regulation of macromitophagy in response to mitochondrial depolarization
GO:0043552--P:positive regulation of phosphatidylinositol 3-kinase activity
GO:2000785--P:regulation of autophagosome assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001917	Ailuropoda melanoleuca	97.43	0.00e+00	1143.00
IUUC-Atr-002557	Amborella trichopoda	37.74	5.00e-30	126.00
IUUC-Apl-004186	Anas platyrhynchos	81.26	0.00e+00	1335.00
IUUC-Aca-004419	Anolis carolinensis	77.87	0.00e+00	1285.00
IUUC-Aly-006308	Arabidopsis lyrata	37.85	1.00e-28	122.00
IUUC-Ath-007656	Arabidopsis thaliana	36.92	3.00e-28	120.00
IUUC-Ame-011354	Astyanax mexicanus	58.34	0.00e+00	857.00
IUUC-Bta-012455	Bos taurus	92.05	0.00e+00	1547.00
IUUC-Bdi-014580	Brachypodium distachyon	42.33	5.00e-30	126.00
IUUC-Bol-016094	Brassica oleracea	40.22	9.00e-29	122.00
IUUC-Bra-017308	Brassica rapa	40.76	1.00e-29	125.00
IUUC-Cja-019073	Callithrix jacchus	98.31	0.00e+00	1096.00
IUUC-Cpo-022101	Cavia porcellus	92.09	0.00e+00	1513.00
IUUC-Csa-023273	Chlorocebus sabaeus	95.38	0.00e+00	2110.00
IUUC-Cin-025567	Ciona intestinalis	52.43	4.00e-56	212.00
IUUC-Csv-026005	Ciona savignyi	51.26	5.00e-56	210.00
IUUC-Dre-028282	Danio rerio	57.64	0.00e+00	844.00
IUUC-Dno-029948	Dasypus novemcinctus	93.55	0.00e+00	1541.00
IUUC-Dor-030568	Dipodomys ordii	94.35	1.00e-162	567.00
IUUC-Ete-032864	Echinops telfairi	81.99	0.00e+00	725.00
IUUC-Eca-034392	Equus caballus	96.12	0.00e+00	2147.00
IUUC-Eeu-034440	Erinaceus europaeus	82.26	0.00e+00	633.00
IUUC-Fca-035359	Felis catus	93.68	0.00e+00	1536.00
IUUC-Fal-037483	Ficedula albicollis	80.82	0.00e+00	1367.00
IUUC-Gmo-039343	Gadus morhua	74.86	0.00e+00	776.00
IUUC-Gga-040787	Gallus gallus	79.71	0.00e+00	632.00
IUUC-Gac-041321	Gasterosteus aculeatus	61.90	0.00e+00	1312.00
IUUC-Gma-044022	Glycine max	36.63	3.00e-29	124.00
IUUC-Ggo-044775	Gorilla gorilla	97.80	0.00e+00	1071.00
IUUC-Hsa-045708	Homo sapiens	94.28	0.00e+00	1574.00
IUUC-Hvu-047536	Hordeum vulgare	41.57	2.00e-29	124.00
IUUC-Itr-048376	Ictidomys tridecemlineatus	96.86	2.00e-170	592.00
IUUC-Lch-050255	Latimeria chalumnae	74.52	0.00e+00	1067.00
IUUC-Lpe-050684	Leersia perrieri	41.76	2.00e-30	127.00
IUUC-Loc-052881	Lepisosteus oculatus	65.84	0.00e+00	999.00
IUUC-Laf-053342	Loxodonta africana	95.69	0.00e+00	1315.00
IUUC-Mcc-055848	Macaca mulatta	91.36	0.00e+00	1554.00
IUUC-Meu-056320	Macropus eugenii	93.26	1.00e-149	524.00
IUUC-Mtr-058685	Medicago truncatula	39.68	3.00e-29	123.00
IUUC-Mga-059401	Meleagris gallopavo	85.19	0.00e+00	1070.00
IUUC-Mmr-061037	Microcebus murinus	94.69	0.00e+00	1567.00
IUUC-Mdo-062484	Monodelphis domestica	72.61	0.00e+00	1135.00
IUUC-Mmu-064090	Mus musculus	92.20	0.00e+00	1533.00
IUUC-Mac-065675	Musa acuminata	35.32	2.00e-29	124.00
IUUC-Mpu-066165	Mustela putorius furo	97.19	0.00e+00	2077.00
IUUC-Mlu-068038	Myotis lucifugus	92.93	0.00e+00	1565.00
IUUC-Nle-069361	Nomascus leucogenys	97.57	0.00e+00	1284.00
IUUC-Opr-070360	Ochotona princeps	84.14	0.00e+00	1156.00
IUUC-Ont-071277	Oreochromis niloticus	60.91	0.00e+00	1194.00
IUUC-Oan-073623	Ornithorhynchus anatinus	83.68	0.00e+00	1482.00
IUUC-Ocu-074600	Oryctolagus cuniculus	95.76	0.00e+00	1936.00
IUUC-Oba-075024	Oryza barthii	34.30	4.00e-32	133.00
IUUC-Obr-076172	Oryza brachyantha	34.71	6.00e-33	135.00
IUUC-Ogl-077411	Oryza glaberrima	34.30	6.00e-32	132.00
IUUC-Ogu-078025	Oryza glumaepatula	38.19	7.00e-32	132.00
IUUC-Oni-082463	Oryza nivara	34.30	4.00e-32	133.00
IUUC-Opu-084041	Oryza punctata	38.19	1.00e-31	131.00
IUUC-Oru-085075	Oryza rufipogon	38.19	1.00e-31	131.00
IUUC-Osa-085781	Oryza sativa	34.30	6.00e-32	132.00
IUUC-Ola-086729	Oryzias latipes	62.36	0.00e+00	931.00
IUUC-Olu-087735	Ostreococcus lucimarinus	40.32	7.00e-24	105.00
IUUC-Oga-089113	Otolemur garnettii	94.48	0.00e+00	1492.00
IUUC-Oar-090171	Ovis aries	94.82	0.00e+00	1412.00
IUUC-Ptr-090970	Pan troglodytes	94.38	0.00e+00	1576.00
IUUC-Pan-092778	Papio anubis	95.21	0.00e+00	2124.00
IUUC-Psi-093571	Pelodiscus sinensis	78.95	0.00e+00	1352.00
IUUC-Pma-094563	Petromyzon marinus	73.75	2.00e-105	374.00
IUUC-Ppa-095832	Physcomitrella patens	36.70	3.00e-30	127.00
IUUC-Pfo-097365	Poecilia formosa	60.34	0.00e+00	840.00
IUUC-Pab-098647	Pongo abelii	91.95	0.00e+00	905.00
IUUC-Pop-099742	Populus trichocarpa	40.32	2.00e-29	124.00
IUUC-Pca-101035	Procavia capensis	77.83	4.00e-156	546.00
IUUC-Ppe-101783	Prunus persica	42.22	2.00e-29	124.00
IUUC-Pva-103187	Pteropus vampyrus	99.13	0.00e+00	705.00
IUUC-Rno-105701	Rattus norvegicus	92.40	0.00e+00	1522.00
IUUC-Sha-107612	Sarcophilus harrisii	83.42	0.00e+00	1385.00
IUUC-Smo-109107	Selaginella moellendorffii	39.66	4.00e-27	116.00
IUUC-Sit-110786	Setaria italica	38.12	2.00e-32	134.00
IUUC-Sly-110859	Solanum lycopersicum	38.10	6.00e-32	132.00
IUUC-Stu-112031	Solanum tuberosum	38.57	5.00e-32	132.00
IUUC-Sar-113242	Sorex araneus	78.17	3.00e-173	602.00
IUUC-Ssc-116094	Sus scrofa	94.80	0.00e+00	1563.00
IUUC-Tru-118308	Takifugu rubripes	54.39	0.00e+00	1049.00
IUUC-Tsy-119552	Tarsius syrichta	99.66	2.00e-174	607.00
IUUC-Tca-121616	Theobroma cacao	37.80	6.00e-31	129.00
IUUC-Tae-124768	Triticum aestivum	42.17	5.00e-30	125.00
IUUC-Tur-126480	Triticum urartu	42.17	2.00e-30	127.00
IUUC-Tbe-127902	Tupaia belangeri	81.42	0.00e+00	663.00
IUUC-Ttr-129278	Tursiops truncatus	99.44	0.00e+00	704.00
IUUC-Vpa-130741	Vicugna pacos	87.93	0.00e+00	837.00
IUUC-Vvi-131437	Vitis vinifera	45.45	6.00e-29	122.00
IUUC-Xtr-132247	Xenopus tropicalis	60.09	0.00e+00	823.00
IUUC-Xma-134277	Xiphophorus maculatus	60.48	0.00e+00	942.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence