iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066617

Ensembl Protein ID

ENSMPUP00000007298.1

UniProt Accession

M3Y7J1; M3Y7J1_MUSPF

Genbank Protein ID

ENSMPUP00000007298

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01016110

Gene Name

ERCC8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000007355.1	ENSMPUT00000007417.1	ENSMPUP00000007298.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.50e-30	101.7	184	218
UBD/Beta-Prp	6.10e-41	140.5	172	361

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd.tllvsGsdDgtikvWDlrt 32
           gH  ++ ++++   +   l+++s D  +k+WD+r+
   Q: 184  GHRQEILAVSWspRCeYVLATASADSRVKLWDVRR 218
           89*********97444669*************986 PP

UBD/Beta-Prp

   S: 80   dlstgkcvhtlkghedsvlslsfsp.sgdklvsGshdrtirvwdletgq.clee..............tlsghdgvvncvvvhpdgnll 152
           dl++g+c h+l+gh +++l++s+sp   ++l+++s+d+ +++wd++  + cl +               ++ h+g vn++++ +dg  l
   Q: 172  DLKSGSCSHILQGHRQEILAVSWSPrCEYVLATASADSRVKLWDVRRASgCLITldqhngkksqavesANTAHNGKVNGLCFTSDGLHL 260
           7899*********************555*****************987636666********************************99* PP
   S: 153  vsGslDrtvrlWdlktgk.llrtltgghtdsvyslsfdsng...kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderl 237
            + ++D+ +rlW++++g+  l    + ++ds + l+f+ +     e+v + + +t+ ++ + +ge +  l+gh + v +  f++n + l
   Q: 261  LTVGTDNRMRLWNSSNGEnTLVNYGKVNNDSRKGLKFTVSCgcsSEFVFVPYGSTIAVYTIYSGEQITMLKGHYKSVDCCVFHSNFQEL 349
           ************996654144444556999999999887657779******************************************** PP
   S: 238  vsgssDgsiriW 249
           +sgs D  i  W
   Q: 350  YSGSRDCNILAW 361
           *********999 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MLGFLLARQA GLDDPLRLRR AESTRRVLGL ELNKDRDVER IHGSGVNTLD IEPVEARYML 60
SGGSDGVIVL YDLENSSRQP YYTCKAVCSV GRSHPDVHKY SVETVQWYPH DTGMFTSSSF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTAGGGT TTTTATTAGC AAGACAGGCG GGTTTGGACG ACCCTCTTCG CCTCCGGAGA 60
GCGGAGTCCA CACGGAGGTA AAGAAAACCT TATTTTTTTC CTCAAACGGG CCATTTCAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0031464--C:Cul4A-RING E3 ubiquitin ligase complex
GO:0016363--C:nuclear matrix
GO:0000109--C:nucleotide-excision repair complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0000209--P:protein polyubiquitination
GO:0006979--P:response to oxidative stress
GO:0009411--P:response to UV
GO:0010165--P:response to X-ray
GO:0006283--P:transcription-coupled nucleotide-excision repair

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001170	Aegilops tauschii	31.03	1.00e-36	148.00
IUUC-Aml-002201	Ailuropoda melanoleuca	96.97	0.00e+00	808.00
IUUC-Atr-002784	Amborella trichopoda	38.16	1.00e-40	160.00
IUUC-Apl-003202	Anas platyrhynchos	80.10	0.00e+00	658.00
IUUC-Aca-004708	Anolis carolinensis	81.90	4.00e-176	610.00
IUUC-Aly-006144	Arabidopsis lyrata	39.61	1.00e-43	171.00
IUUC-Ath-006673	Arabidopsis thaliana	40.67	3.00e-45	176.00
IUUC-Acl-008195	Aspergillus clavatus	38.64	3.00e-42	166.00
IUUC-Afl-008406	Aspergillus flavus	37.30	2.00e-38	153.00
IUUC-Afu-008759	Aspergillus fumigatus	33.83	5.00e-40	158.00
IUUC-Ani-009380	Aspergillus nidulans	35.43	1.00e-40	160.00
IUUC-Ang-009820	Aspergillus niger	37.10	2.00e-38	153.00
IUUC-Aor-010092	Aspergillus oryzae	37.55	9.00e-43	167.00
IUUC-Ate-010491	Aspergillus terreus	34.45	8.00e-44	171.00
IUUC-Bta-012825	Bos taurus	94.96	0.00e+00	781.00
IUUC-Bci-013856	Botrytis cinerea	32.13	1.00e-52	200.00
IUUC-Bdi-014899	Brachypodium distachyon	33.74	5.00e-65	242.00
IUUC-Bol-015337	Brassica oleracea	40.67	1.00e-43	170.00
IUUC-Bra-018089	Brassica rapa	40.67	3.00e-44	172.00
IUUC-Cja-018725	Callithrix jacchus	93.69	0.00e+00	781.00
IUUC-Cfa-021162	Canis familiaris	97.47	0.00e+00	805.00
IUUC-Cpo-022190	Cavia porcellus	92.68	0.00e+00	778.00
IUUC-Cre-022960	Chlamydomonas reinhardtii	37.62	8.00e-40	158.00
IUUC-Csa-023610	Chlorocebus sabaeus	94.19	0.00e+00	789.00
IUUC-Cho-024689	Choloepus hoffmanni	93.24	0.00e+00	717.00
IUUC-Cin-025324	Ciona intestinalis	39.16	1.00e-81	296.00
IUUC-Csv-026059	Ciona savignyi	38.44	2.00e-73	269.00
IUUC-Cgl-026384	Colletotrichum gloeosporioides	34.49	1.00e-38	154.00
IUUC-Cme-027182	Cyanidioschyzon merolae	28.66	6.00e-13	69.30
IUUC-Dre-028696	Danio rerio	73.50	3.00e-178	617.00
IUUC-Dno-029102	Dasypus novemcinctus	94.95	0.00e+00	789.00
IUUC-Dor-030361	Dipodomys ordii	76.77	2.00e-178	618.00
IUUC-Dse-031167	Dothistroma septosporum	30.31	2.00e-44	173.00
IUUC-Ete-032856	Echinops telfairi	77.27	1.00e-178	618.00
IUUC-Eca-033611	Equus caballus	96.15	0.00e+00	680.00
IUUC-Eeu-034583	Erinaceus europaeus	72.98	2.00e-163	568.00
IUUC-Fca-036481	Felis catus	96.46	0.00e+00	800.00
IUUC-Fal-037327	Ficedula albicollis	78.82	3.00e-165	574.00
IUUC-Fox-037684	Fusarium oxysporum	29.67	8.00e-44	171.00
IUUC-Fso-038306	Fusarium solani	31.38	2.00e-54	206.00
IUUC-Gmo-039043	Gadus morhua	69.62	8.00e-167	579.00
IUUC-Ggr-039783	Gaeumannomyces graminis	32.28	8.00e-39	154.00
IUUC-Gga-041085	Gallus gallus	86.78	0.00e+00	638.00
IUUC-Gac-042328	Gasterosteus aculeatus	68.16	2.00e-160	558.00
IUUC-Gma-043004	Glycine max	32.79	6.00e-57	214.00
IUUC-Ggo-045627	Gorilla gorilla	85.32	0.00e+00	704.00
IUUC-Hsa-046028	Homo sapiens	94.19	0.00e+00	789.00
IUUC-Hvu-047678	Hordeum vulgare	32.38	2.00e-35	142.00
IUUC-Itr-048648	Ictidomys tridecemlineatus	94.19	0.00e+00	788.00
IUUC-Kpa-049386	Komagataella pastoris	30.05	6.00e-44	171.00
IUUC-Lch-050590	Latimeria chalumnae	79.60	1.00e-160	558.00
IUUC-Lpe-051725	Leersia perrieri	34.20	2.00e-36	146.00
IUUC-Loc-051788	Lepisosteus oculatus	75.26	2.00e-180	624.00
IUUC-Lma-053082	Leptosphaeria maculans	32.84	9.00e-54	204.00
IUUC-Laf-053809	Loxodonta africana	94.96	0.00e+00	793.00
IUUC-Mcc-054998	Macaca mulatta	94.31	5.00e-161	559.00
IUUC-Meu-055929	Macropus eugenii	77.39	0.00e+00	630.00
IUUC-Mor-057003	Magnaporthe oryzae	33.33	7.00e-47	181.00
IUUC-Mtr-057921	Medicago truncatula	32.33	2.00e-56	213.00
IUUC-Mga-059449	Meleagris gallopavo	65.88	5.00e-125	440.00
IUUC-Mmr-061609	Microcebus murinus	90.79	0.00e+00	729.00
IUUC-Mdo-062564	Monodelphis domestica	85.14	0.00e+00	716.00
IUUC-Mmu-063904	Mus musculus	89.67	0.00e+00	746.00
IUUC-Mac-064716	Musa acuminata	37.50	1.00e-40	160.00
IUUC-Mlu-067054	Myotis lucifugus	92.68	0.00e+00	769.00
IUUC-Nfi-068467	Neosartorya fischeri	36.90	5.00e-34	138.00
IUUC-Nle-069731	Nomascus leucogenys	94.19	0.00e+00	789.00
IUUC-Opr-070297	Ochotona princeps	68.62	5.00e-88	318.00
IUUC-Ont-072558	Oreochromis niloticus	70.57	1.00e-164	572.00
IUUC-Oan-072864	Ornithorhynchus anatinus	87.72	1.00e-27	113.00
IUUC-Ocu-074415	Oryctolagus cuniculus	93.94	0.00e+00	786.00
IUUC-Oba-075759	Oryza barthii	41.05	2.00e-43	169.00
IUUC-Obr-076387	Oryza brachyantha	39.34	1.00e-45	177.00
IUUC-Ogl-077924	Oryza glaberrima	41.13	1.00e-17	83.20
IUUC-Ogu-078186	Oryza glumaepatula	34.72	3.00e-63	235.00
IUUC-Oin-079389	Oryza indica	34.56	9.00e-47	180.00
IUUC-Olo-080916	Oryza longistaminata	28.92	2.00e-17	81.60
IUUC-Ome-081471	Oryza meridionalis	40.00	2.00e-40	160.00
IUUC-Oni-082449	Oryza nivara	40.53	2.00e-40	160.00
IUUC-Opu-083210	Oryza punctata	40.53	3.00e-43	169.00
IUUC-Oru-085159	Oryza rufipogon	41.05	1.00e-43	170.00
IUUC-Osa-085926	Oryza sativa	41.89	5.00e-33	133.00
IUUC-Ola-087084	Oryzias latipes	68.61	5.00e-167	580.00
IUUC-Olu-087853	Ostreococcus lucimarinus	29.55	7.00e-40	157.00
IUUC-Oga-089008	Otolemur garnettii	92.98	0.00e+00	774.00
IUUC-Oar-089259	Ovis aries	94.96	0.00e+00	782.00
IUUC-Ptr-091112	Pan troglodytes	93.64	0.00e+00	779.00
IUUC-Pan-092303	Papio anubis	93.75	7.00e-71	258.00
IUUC-Psi-093050	Pelodiscus sinensis	83.42	0.00e+00	695.00
IUUC-Pma-094259	Petromyzon marinus	58.66	1.00e-130	459.00
IUUC-Pno-094798	Phaeosphaeria nodorum	31.54	2.00e-50	193.00
IUUC-Ppa-095477	Physcomitrella patens	32.03	2.00e-56	213.00
IUUC-Pfo-096855	Poecilia formosa	67.91	1.00e-163	569.00
IUUC-Pab-098096	Pongo abelii	93.43	0.00e+00	782.00
IUUC-Pop-098800	Populus trichocarpa	36.84	2.00e-45	176.00
IUUC-Pca-100187	Procavia capensis	94.66	1.00e-114	405.00
IUUC-Ppe-101759	Prunus persica	38.22	3.00e-44	172.00
IUUC-Pva-102438	Pteropus vampyrus	80.00	5.00e-93	334.00
IUUC-Pte-104197	Pyrenophora teres	32.77	3.00e-48	186.00
IUUC-Pyt-104421	Pyrenophora triticirepentis	33.33	4.00e-48	185.00
IUUC-Rno-106087	Rattus norvegicus	89.92	0.00e+00	750.00
IUUC-Sce-106276	Saccharomyces cerevisiae	27.32	1.00e-12	68.20
IUUC-Sha-106831	Sarcophilus harrisii	82.41	0.00e+00	682.00
IUUC-Sja-107681	Schizosaccharomyces japonicus	34.13	2.00e-57	216.00
IUUC-Spo-108294	Schizosaccharomyces pombe	35.82	8.00e-65	240.00
IUUC-Ssl-108613	Sclerotinia sclerotiorum	32.10	1.00e-50	194.00
IUUC-Smo-109008	Selaginella moellendorffii	40.65	1.00e-76	280.00
IUUC-Sit-110300	Setaria italica	30.07	9.00e-52	197.00
IUUC-Sly-111441	Solanum lycopersicum	31.37	7.00e-48	184.00
IUUC-Stu-111995	Solanum tuberosum	31.28	5.00e-48	185.00
IUUC-Sar-113196	Sorex araneus	84.03	1.00e-128	452.00
IUUC-Sbi-113790	Sorghum bicolor	40.00	2.00e-42	166.00
IUUC-Ssc-115609	Sus scrofa	95.45	0.00e+00	797.00
IUUC-Tgu-116927	Taeniopygia guttata	81.45	0.00e+00	665.00
IUUC-Tru-118164	Takifugu rubripes	69.73	1.00e-171	595.00
IUUC-Tsy-119151	Tarsius syrichta	88.38	0.00e+00	730.00
IUUC-Tni-120896	Tetraodon nigroviridis	69.00	8.00e-162	563.00
IUUC-Tca-121592	Theobroma cacao	38.22	1.00e-44	174.00
IUUC-Tre-122023	Trichoderma reesei	34.85	5.00e-49	188.00
IUUC-Tvi-122507	Trichoderma virens	36.05	7.00e-50	191.00
IUUC-Tae-125276	Triticum aestivum	33.97	1.00e-59	223.00
IUUC-Tur-126092	Triticum urartu	31.27	2.00e-34	140.00
IUUC-Tbe-127422	Tupaia belangeri	71.62	1.00e-151	528.00
IUUC-Ttr-129097	Tursiops truncatus	92.17	0.00e+00	770.00
IUUC-Vda-130014	Verticillium dahliae	36.36	5.00e-49	188.00
IUUC-Vpa-130782	Vicugna pacos	95.21	0.00e+00	791.00
IUUC-Vvi-131494	Vitis vinifera	36.89	4.00e-44	172.00
IUUC-Xtr-132165	Xenopus tropicalis	77.84	9.00e-180	622.00
IUUC-Xma-133205	Xiphophorus maculatus	68.58	3.00e-167	581.00
IUUC-Yli-134614	Yarrowia lipolytica	33.67	3.00e-57	215.00
IUUC-Zma-135861	Zea mays	34.39	2.00e-59	223.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence