iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003867

Ensembl Protein ID

ENSAPLP00000004777.1

UniProt Accession

R0LSQ0; R0LSQ0_ANAPL

Genbank Protein ID

EOB08784.1

Protein Name

E3 ubiquitin-protein ligase MIB1

Genbank Nucleotide ID

ADON01003154

Gene Name

MIB1; Anapl_02292

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000005158.1	ENSAPLT00000005397.1	ENSAPLP00000004777.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	92.13	0.00e+00	1918.00	IUUC-Dre-028261
E3 activity/RING/RING	66.26	0.00e+00	1305.00	IUUC-Dme-031616
E3 activity/RING/RING	99.09	0.00e+00	1999.00	IUUC-Hsa-046439
E3 activity/RING/RING	98.89	0.00e+00	1995.00	IUUC-Mmu-063520

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

ARVVRGPDWK WGKQDGGEGH VGTVRSFESP EEVVVVWDNG TAANYRCSGA YDLRILDSAP 60
TGIKHDGTMC DTCRQQPIIG IRWKCAECTN YDLCTVCYHG DKHHLRHRFY RITTPGSERV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCCGGGTGG TGCGGGGCCC CGACTGGAAG TGGGGGAAGC AGGACGGCGG CGAGGGCCAC 60
GTGGGCACGG TGCGCAGCTT CGAGAGCCCC GAGGAGGTGG TGGTGGTGTG GGACAACGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0040--ANK repeat
KW-0181--Complete proteome
KW-0436--Ligase
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR001370--BIR_rpt
IPR010606--Mib_Herc2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR000433--Znf_ZZ

PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS51416--MIB_HERC2
PS50089--ZF_RING_2
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF12796--Ank_2
PF06701--MIB_HERC2
PF00569--ZZ

PRINTS

PR01415--ANKYRIN

SMART

SM00248--ANK
SM00184--RING
SM00291--ZnF_ZZ

Gene Ontology

GO:0005813--C:centrosome
GO:0031410--C:cytoplasmic vesicle
GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0001568--P:blood vessel development
GO:0001947--P:heart looping
GO:0045665--P:negative regulation of neuron differentiation
GO:0001841--P:neural tube formation
GO:0007219--P:Notch signaling pathway
GO:0045807--P:positive regulation of endocytosis
GO:0001756--P:somitogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001993	Ailuropoda melanoleuca	99.19	0.00e+00	1977.00
IUUC-Atr-002913	Amborella trichopoda	27.54	1.00e-21	99.00
IUUC-Aca-004471	Anolis carolinensis	99.29	0.00e+00	2000.00
IUUC-Aly-006101	Arabidopsis lyrata	28.67	3.00e-18	86.30
IUUC-Ath-007301	Arabidopsis thaliana	29.46	6.00e-20	92.00
IUUC-Ang-009817	Aspergillus niger	36.24	5.00e-31	128.00
IUUC-Ame-011923	Astyanax mexicanus	87.43	0.00e+00	1804.00
IUUC-Bta-012972	Bos taurus	99.19	0.00e+00	2000.00
IUUC-Cel-018156	Caenorhabditis elegans	23.46	1.00e-23	104.00
IUUC-Cja-019044	Callithrix jacchus	94.47	0.00e+00	1807.00
IUUC-Cfa-020049	Canis familiaris	97.28	0.00e+00	1952.00
IUUC-Cpo-022228	Cavia porcellus	98.71	0.00e+00	1865.00
IUUC-Csa-023228	Chlorocebus sabaeus	98.99	0.00e+00	1997.00
IUUC-Cho-024456	Choloepus hoffmanni	86.82	0.00e+00	794.00
IUUC-Cin-025506	Ciona intestinalis	71.83	0.00e+00	872.00
IUUC-Csv-026037	Ciona savignyi	65.24	0.00e+00	1196.00
IUUC-Dre-028261	Danio rerio	92.13	0.00e+00	1922.00
IUUC-Dno-029816	Dasypus novemcinctus	99.19	0.00e+00	1999.00
IUUC-Dor-030678	Dipodomys ordii	79.09	0.00e+00	1417.00
IUUC-Dme-031616	Drosophila melanogaster	60.25	0.00e+00	1196.00
IUUC-Eca-033837	Equus caballus	99.14	0.00e+00	1871.00
IUUC-Eeu-034896	Erinaceus europaeus	84.56	0.00e+00	681.00
IUUC-Fca-036568	Felis catus	99.24	0.00e+00	1858.00
IUUC-Fal-037586	Ficedula albicollis	99.60	0.00e+00	2005.00
IUUC-Gmo-038802	Gadus morhua	90.42	0.00e+00	1875.00
IUUC-Gga-040131	Gallus gallus	100.00	0.00e+00	2013.00
IUUC-Gac-042052	Gasterosteus aculeatus	91.15	0.00e+00	1922.00
IUUC-Ggo-044970	Gorilla gorilla	99.09	0.00e+00	1999.00
IUUC-Hsa-046439	Homo sapiens	99.09	0.00e+00	1999.00
IUUC-Itr-048363	Ictidomys tridecemlineatus	98.48	0.00e+00	808.00
IUUC-Lch-049434	Latimeria chalumnae	91.44	0.00e+00	1839.00
IUUC-Lpe-051464	Leersia perrieri	26.46	8.00e-16	80.10
IUUC-Loc-052278	Lepisosteus oculatus	90.95	0.00e+00	1867.00
IUUC-Laf-054292	Loxodonta africana	98.49	0.00e+00	1854.00
IUUC-Meu-056752	Macropus eugenii	80.00	4.00e-147	515.00
IUUC-Mpo-057569	Magnaporthe poae	36.90	5.00e-33	135.00
IUUC-Mga-059408	Meleagris gallopavo	99.57	0.00e+00	1892.00
IUUC-Mmr-061628	Microcebus murinus	99.19	0.00e+00	2001.00
IUUC-Mdo-062055	Monodelphis domestica	99.39	0.00e+00	2003.00
IUUC-Mmu-063520	Mus musculus	98.89	0.00e+00	2032.00
IUUC-Mac-065553	Musa acuminata	26.59	7.00e-17	82.80
IUUC-Mpu-065864	Mustela putorius furo	99.19	0.00e+00	2001.00
IUUC-Mlu-067802	Myotis lucifugus	99.25	0.00e+00	1872.00
IUUC-Nle-069568	Nomascus leucogenys	97.68	0.00e+00	1958.00
IUUC-Opr-071018	Ochotona princeps	78.11	1.00e-171	597.00
IUUC-Ont-072079	Oreochromis niloticus	91.84	0.00e+00	1941.00
IUUC-Oan-073346	Ornithorhynchus anatinus	99.84	0.00e+00	1284.00
IUUC-Ocu-073932	Oryctolagus cuniculus	99.29	0.00e+00	2002.00
IUUC-Oba-075968	Oryza barthii	27.08	8.00e-16	80.10
IUUC-Obr-076548	Oryza brachyantha	26.77	3.00e-20	94.70
IUUC-Ogl-077477	Oryza glaberrima	27.08	8.00e-16	80.10
IUUC-Oin-079705	Oryza indica	27.08	9.00e-16	79.70
IUUC-Ome-081845	Oryza meridionalis	27.08	3.00e-16	81.30
IUUC-Oni-082073	Oryza nivara	28.17	8.00e-19	88.20
IUUC-Opu-083740	Oryza punctata	26.40	1.00e-16	82.40
IUUC-Osa-085560	Oryza sativa	28.17	8.00e-19	88.20
IUUC-Ola-087184	Oryzias latipes	91.63	0.00e+00	1905.00
IUUC-Oga-089002	Otolemur garnettii	96.46	0.00e+00	1979.00
IUUC-Oar-089440	Ovis aries	99.14	0.00e+00	1875.00
IUUC-Ptr-090690	Pan troglodytes	98.59	0.00e+00	1982.00
IUUC-Pan-092295	Papio anubis	98.99	0.00e+00	1997.00
IUUC-Psi-093118	Pelodiscus sinensis	99.60	0.00e+00	1991.00
IUUC-Pma-094438	Petromyzon marinus	89.33	0.00e+00	673.00
IUUC-Pfo-096302	Poecilia formosa	87.63	0.00e+00	1815.00
IUUC-Pab-097804	Pongo abelii	98.52	0.00e+00	1095.00
IUUC-Pca-101028	Procavia capensis	90.38	0.00e+00	826.00
IUUC-Pva-102890	Pteropus vampyrus	92.47	0.00e+00	873.00
IUUC-Rno-105470	Rattus norvegicus	98.28	0.00e+00	1990.00
IUUC-Sha-106650	Sarcophilus harrisii	99.08	0.00e+00	1957.00
IUUC-Sly-111367	Solanum lycopersicum	25.74	9.00e-21	96.30
IUUC-Sar-113247	Sorex araneus	85.47	0.00e+00	773.00
IUUC-Ssc-115706	Sus scrofa	99.29	0.00e+00	2002.00
IUUC-Tgu-116863	Taeniopygia guttata	99.70	0.00e+00	2003.00
IUUC-Tru-117733	Takifugu rubripes	91.16	0.00e+00	1908.00
IUUC-Tsy-119313	Tarsius syrichta	99.00	0.00e+00	1383.00
IUUC-Tni-120601	Tetraodon nigroviridis	92.67	0.00e+00	1891.00
IUUC-Tbe-127979	Tupaia belangeri	94.21	0.00e+00	1536.00
IUUC-Ttr-128673	Tursiops truncatus	99.09	0.00e+00	1998.00
IUUC-Vda-129784	Verticillium dahliae	35.21	5.00e-32	133.00
IUUC-Vpa-130332	Vicugna pacos	95.36	0.00e+00	1916.00
IUUC-Xtr-132423	Xenopus tropicalis	96.67	0.00e+00	1961.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence